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Carbon-based nanomaterials cause toxicity by oxidative stress to the liver and brain in Sprague-Dawley rats

Nuclear Science and Techniques 2024年第6期35卷 54-64页

作者： Ying-Ying Xu Chan Jin Meng Wu Jian-Ye Zhou hui-ling wei Department of Gastroenterology China-Japan Friendship HospitalBeijing 100029China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Institute of Particle and Nuclear Physics College of PhysicsHenan Normal UniversityXinxiang 453007China

Carbon-based nanomaterials have important research significance in various disciplines,such as composite materials,nanoelectronic devices,biosensors,biological imaging,and drug ***,the human and ecological risks associated with carbon-based nanomaterials have received increasing ***,the biological safety of carbon based nanomaterials has not been systematically *** this study,we used different types of carbon materials,namely,graphene oxide(GO),single-walled carbon nanotubes(SWCNTs),and multiwalled carbon nanotubes(MWCNTs),as models to observe their distribution and oxidative damage in *** results of Histopathological and ultrastructural examinations indicated that the liver and lungs were the main accumulation targets of these ***-μ-XRF analysis revealed that SWCNTs and MWCNTs might be present in the *** shows that the three types of carbon-based nanomaterials could cross the gas-blood barrier and eventually reach the liver *** addition,SWCNTs and MWCNTs could cross the blood-brain barrier and accumulate in the cerebral *** increase in ROS and MDA levels and the decrease in GSH,SOD,and CAT levels indicated that the three types of nanomaterials might cause oxidative stress in the *** suggests that direct instillation of these carbon-based nanomaterials into rats could induce ROS *** addition,iron(Fe)contaminants in these nanomaterials were a definite source of free ***,these nanomaterials did not cause obvious damage to the rat brain *** deposition of selenoprotein in the rat brain was found to be related to oxidative stress and Fe *** information may support the development of secure and reasonable applications of the studied carbon-based nanomaterials.

关键词： Carbon-based nanomaterials Oxidative stress Trace element distribution TEM SR-μ-XRF

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A possible probe to neutron-skin thickness by fragment parallel momentum distribution in projectile fragmentation reactions

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Nuclear Science and Techniques 2024年第6期35卷 114-119页

作者： Chun-Wang Ma Yi-Jie Duan Ya-Fei Guo Chun-Yuan Qiao Yu-Ting Wang Jie Pu Kai-Xuan Cheng hui-ling wei College of Physics Henan Normal UniversityXinxiang 453007China Institute of Nuclear Science and Technology Henan Academy of SciencesZhengzhou 450015China

Neutron-skin thickness is a key parameter for a neutron-rich nucleus;however,it is difficult to *** the framework of the Lanzhou Quantum Molecular Dynamics(LQMD)model,a possible probe for the neutron-skin thickness(δ_(np))of neutron-rich ^(48)Ca was studied in the 140A MeV ^(48)Ca+^(9)Be projectile fragmentation reaction based on the parallel momentum distribution(p∥)of the residual fragments.A Fermi-type density distribution was employed to initiate the neutron density distributions in the LQMD simulations.A combined Gaussian function with different width parameters for the left side(Γ_(L))and the right side(Γ_(R))in the distribution was used to describe the p∥of the residual *** neutron-rich sulfur isotopes as examples,Γ_(L) shows a sensitive correlation withδ_(np) of ^(48)Ca,and is proposed as a probe for determining the neutron skin thickness of the projectile nucleus.

关键词： Neutron-skin thickness Projectile fragmentation Parallel momentum distribution Neutron-rich nucleus Quantum molecular dynamics model

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Isoscaling properties for neutron-rich fragments in highly asymmetric heavy ion collision systems

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Chinese Physics C 2024年第6期48卷 136-144页

作者：彭丹马春旺乔春源刘星泉魏慧玲 Institute of Particle and Nuclear Physics College of PhysicsHenan Normal UniversityXinxiang 453007China Institute of Nuclear Science and Technology Henan Academy of SciencesZhengzhou 450046China Key Laboratory of Radiation Physics and Technology of the Ministry of Education Sichuan UniversityChengdu 610064China

Traditionally,isoscaling has been interpreted and applied within the framework of the grand canonical ensemble,based on the assumption that fragment production occurs following the attainment of a statistical equilibrium ***,the influence of the symmetry energy can lead to differences in the neutron and density distribution in neutron-rich *** in turn may impact the iso scaling parameters(usually denoted byαandβ).We examine the isoscaling properties for neutron-rich fragments produced in highly asymmetric systems on inverse kinematics,namely^(40,48)Ca and ^(58,64)Ni+^(9)Be at 140 MeV per *** evaluate α and β values and sort them as a function of the neutron excess I≡*** significant differences in a extracted from fragments within different ranges of I emphasize the importance of understanding the dependence of isoscaling parameters on fragments generated in various collision ***,the|β(N)|/α(Z)value for a specific fragment in small size and highly iso spin asymmetry systems can serve as a probe to detect the variations in neutron density and proton density in different regions of the nucleus and indicate the limitations of theoretical models in investigating these issues.

关键词： isoscaling symmetry energy nuclear density neutron-rich fragment heavy ion collision

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Configurational information entropy analysis of fragment mass cross distributions to determine the neutron skin thickness of projectile nuclei

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Nuclear Science and Techniques 2022年第9期33卷 21-27页

作者： hui-ling wei Xun Zhu Chen Yuan College of Physics Henan Normal UniversityXinxiang 453007China

Configurational information entropy(CIE)analysis has been shown to be applicable for determining the neutron skin thickness(δnp)of neutron-rich nuclei from fragment production in projectile fragmentation *** BNN+FRACS machine learning model was adopted to predict the fragment mass cross-sections(σ_(A))of the projectile fragmentation reactions induced by calcium isotopes from ^(36)Ca to ^(56)Ca on a ^(9)Be target at 140MeV/*** fast Fourier transform was adopted to decompose the possible information compositions inσA distributions and determine the quantity of CIE(S_(A)[f]).It was found that the range of fragments significantly influences the quantity of S_(A)[f],which results in different trends of S_(A)[f]~δnp *** linear S_(A)[f]~δnp correlation in a previous study[***.33,6(2022)]could be reproduced using fragments with relatively large mass fragments,which verifies that S_(A)[f]determined from fragmentσAis sensitive to the neutron skin thickness of neutron-rich isotopes.

关键词： Neutron skin thickness Mass cross-section distribution Configurational information entropy Projectile fragmentation reaction

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A scaling phenomenon for the cross section of fragment produced in projectile fragmentation reactions

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Science China(Physics,Mechanics & Astronomy) 2019年第9期62卷 60-69页

作者： Yi-Dan Song hui-ling wei Chun-Wang Ma Institute of Particle and Nuclear Physics Henan Normal University

A scaling phenomenon has been found for the cross section of a fragment, which is defined as a "square" cross section(SCS).This phenomenon can unify the cross sections of fragments in projectile fragmentation(PF) reactions. An empirical formula is proposed to calculate SCSfor a fragment with parameters determined by an extensive investigation of measured reactions ranging from Fermi energies to relativistic energies. The scaling phenomenon of SCShas been verified using different techniques,showing that the scaling of SCSgenerally exists in PF reactions. The concept of SCS, which can be assumed as a standard value for a fragment, is shown to accurately predict the cross sections of isotopes in PF reactions with incident energies ranging from tens of A MeV to approximately 1000 A MeV.

关键词： scaling phenomenon cross section prediction intermediate mass fragments projectile fragmentation

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Binding energies of near proton-drip line Z = 22-28 isotopes determined from measured isotopic cross section distributions

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Science China(Physics,Mechanics & Astronomy) 2019年第1期62卷 63-68页

作者： Chun-Wang Ma Yi-Dan Song hui-ling wei College of Physics and Materials Science Henan Normal University Institute of Particle and Nuclear Physics Henan Normal University

A new method is proposed to determine the binding energy(B)of near proton-drip line isotopes from isotopic cross section *** determine B of Z=22-28 isotopes(with T_z=-2 and-5/2),the lack of cross sections for proton-rich isotopes in the 345A MeV^(78)Kr+~9Be is overcome by predicting the proton-rich isotopes from a newly discovered scaling phenomenon found in the proton-rich isotopes measured in the 140A MeV^(40,48)Ca(^(58,64)Ni)+~9Be *** cross sections for proton-rich isotopes are verified to exponentially depend on the average binding energy per nucleon,based on which B of the Z=22-28 isotopes with T_z=-2 and-5/2 are determined from cross *** determined B of the isotopes are justified from obeying the scaling phenomenon of the difference between the mass of mirror *** cross sections for the Z=22-28 isotopes with T_z=-1 and-3/2,which in potential can be experimentally studied in mass storage ring,are also predicted.

关键词： proton drip line binding energy mirror nuclei scaling phenomenon

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Improved FRACS parameterizations for cross sections of isotopes near the proton drip line in projectile fragmentation reactions

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Nuclear Science and Techniques 2018年第7期29卷 133-137页

作者： Yi-Dan Song hui-ling wei Chun-Wang Ma Jian-Hua Chen Institute of Particle and Nuclear Physics Henan Normal University Shanghai Institute of Applied Physics Chinese Academy of Sciences College of Information and Electronic Engineering Shangqiu Institute of Technology

The FRACS parameterizations,labeled as FRACS-C,have been improved in order to predict the presence of isotopes near the proton drip line produced in projectile fragmentation *** investigating the cross sections for proton-rich isotopes in a series of reactions with energies ranging from intermediate to relativistic,it is shown that the FRACS-C parameterizations can predict isotopes near the proton drip line considerably *** FRACS-C parameterizations are suggested to serve as an effective tool for predicting the presence of proton-rich isotopes with large asymmetry in a projectile fragmentation *** reactions have been investigated to check these results.

关键词：同位素质子反应破碎射弹滴线不对称现象有效工具

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Multiple-models predictions for drip line nuclides in projectile fragmentation of^(40,48)Ca,^(58,64)Ni,and^(78,86)Kr at 140 MeV/u

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Nuclear Science and Techniques 2022年第12期33卷 49-58页

作者： Xiao-Bao wei hui-ling wei Yu-Ting Wang Jie Pu Kai-Xuan Cheng Ya-Fei Guo Chun-Wang Ma College of Physics Henan Normal UniversityXinxiang 453007China

Modern rare isotope beam(RIB)factories will significantly enhance the production of extremely rare isotopes(ERI)at or near drip *** one of the most important methods employed in RIB factories,the production of ERIs in projectile fragmentation reactions should be theoretically improved to provide better guidance for experimental *** cross-sections of ERIs produced in 140 MeV/u^(78,86)Kr/^(58,64)Ni/^(40,48)Ca+9Be projectile fragmentation reactions were predicted using the newly proposed models[i.e.,Bayesian neural network(BNN),BNN+FRACS,and FRACS,see ***.C,46:074104(2022)]and the frequently used EPAX3 *** a minimum cross-section of 1015 mb,the possibilities of ERIs discovery in a new facility for rare isotope beams(FRIB)are discussed.

关键词： Bayesian neural network(BNN) FRACS Drip line Extremely rare isotope Projectile fragmentation

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A Bayesian-neural-network prediction for fragment production in proton induced spallation reaction

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Chinese Physics C 2020年第12期44卷 163-170页

作者： Chun-Wang Ma Dan Peng hui-ling wei Yu-Ting Wang Jie Pu Institute of Particle and Nuclear Physics Henan Normal UniversityXinxiang 453007China School of Physics Henan Normal UniversityXinxiang 453007China

Fragment production in spallation reactions yields key infrastructure data for various *** on the empirical SPACS parameterizations,a Bayesian-neural-network(BNN)approach is established to predict the fragment cross sections in proton-induced spallation reactions.A systematic investigation has been performed for the measured proton-induced spallation reactions of systems ranging from intermediate to heavy nuclei systems and incident energies ranging from 168 MeV/u to 1500 MeV/*** learning the residuals between the experimental measurements and SPACS predictions,it is found that the BNN-predicted results are in good agreement with the measured *** established method is suggested to benefit the related research on nuclear astrophysics,nuclear radioactive beam sources,accelerator driven systems,proton therapy,etc.

关键词： Bayesian neural network(BNN) spallation reaction cross sections

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Predictions for cross sections of light proton-rich isotopes in the ^(40)Ca + ~9Be reaction

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Chinese Physics C 2018年第7期42卷 59-64页

作者： Yi-Dan Song hui-ling wei Chun-Wang Ma Institute of Particle and Nuclear Physics Henan Normal University Xinxiang 453007 China Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai 201800 China

The cross sections for Z=10-19 with isotopes Tz=-3/2 to -5 in the 140A MeV 40Ca ＋ 9Be projectile fragmentation reaction have been predicted. An empirical formula based on the correlation between the cross section and average binding energy of an isotope has been adopted to predict the cross section. The binding energies in the AME16, WS4, and the theoretical prediction by the spherical relativistic continuum Hartree-Bogoliubov theory have been used. Meanwhile, the FRACS parametrization and the modified statistical abrasion-ablation model are also used to predict the cross sections for the proton-rich isotopes. The predicted cross sections for the Tz=-3 isotopes are close to 10-10 mb, which hopefully can be studied experimentally. In addition, based on the predicted cross sections, Z=14 is suggested to be a new magic number in the light proton-rich nuclei with Tz ≤ -3/2, for which the phenomenon is much more evident than it is from the average binding energy per nucleon.

关键词： proton-drip line proton-rich isotopes proton magic number binding energy projectile fragmentation

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