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Immunomodulation of artemisinin and its derivatives

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Science Bulletin 2016年第18期61卷 1399-1406页

作者： Wenbo Yao Feng wang hui wang Key Laboratory of Food Safety Research Institute for Nutritional Sciences Shanghai Institutes for Biological SciencesChinese Academy of Sciences University of Chinese Academy of Sciences School of Life Science and Technology ShanghaiTech University Key Laboratory of Food Safety Risk Assessment Ministry of Health

In the 1970 s, artemisinin(‘‘qinghaosu'' in Chinese), a sesquiterpene lactone with an unusual peroxide bridge, was isolated from Artemisia annua L. It showed promising antimalarial activity, particularly by eliminating parasites resistant to chloroquine. For more than 30 years,artemisinin has contributed to worldwide health as a new type of antimalarial drug. Artemisinin and its analogs, such as dihydroartemisinin, artemether, artesunate, artemiside,artemisone, and arteether, possess not only potent antimalarial activity but also anti-viral, antifungal, anticancer,and anti-inflammatory properties. In this review, we discuss the current understanding of how artemisinin and its analogs affect the immune system and immune-related diseases.

关键词： Artemisinin Immune system Immune-related diseases Macrophage T-cell B-cell

Light People:Professor Guangming Tao

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Light(Science & Applications) 2022年第11期11卷 2574-2578页

作者： hui wang Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of Sciences3888 Dong Nan Hu RoadChangchun 130033China

Editorial'In the short but hot summer nights,only by opening doors and windows can the room be cooled down slightly'complained the famous Chinese poet Fu Du in his poem Summer Night Lament more than 1000 years ***,people are suffering from the summer heat,with ambient temperatures around or exceeding 40℃.Phrases such as"killer hot days"are no longer exaggerated *** weather can not only frustrate people,but also make people sick or even endanger lives owing to ***,scientists have come up with a great invention,which will provide us with some much-needed relief in hot summers-the optical *** magic of this innovation is that,although it feels just like a normal fabric and has all the necessary properties of a wearable fabric,a garment made with it can cool down one's body by nearly 5℃even under direct sunlight,making it ideal for summer *** the last few years,a team led by *** Tao of Huazhong University of Science and Technology has achieved remarkable progress in the area of optical metafabrics,finding new applications for this material and making it more ***,please follow our Light Science Editor as he explores this amazing new material and finds how it has been used in the industry,society,and Winter Olympics.

关键词： please exceeding suffering

Vibration attenuation performance of wind turbine tower using a prestressed tuned mass damper under seismic excitation

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Earthquake Engineering and Engineering Vibration 2024年第2期23卷 511-524页

作者： Lei Zhenbo Liu Gang wang hui hui Yi School of Civil Engineering Chongqing UniversityChongqing 400045China Key Laboratory of New Technology for Construction of Cities in Mountain Area Chongqing UniversityMinistry of EducationChongqing 400045China

With the rapid development of large megawatt wind turbines,the operation environment of wind turbine towers(WTTs)has become increasingly *** particular,seismic excitation can create a resonance response and cause excessive vibration of the *** investigate the vibration attenuation performance of the WTT under seismic excitations,a novel passive vibration control device,called a prestressed tuned mass damper(PS-TMD),is presented in this ***,a mathematical model is established based on structural dynamics under seismic ***,the mathematical analytical expression of the dynamic coefficient is deduced,and the parameter design method is obtained by system tuning ***,based on a theoretical analysis and parameter design,the numerical results showed that the PS-TMD was able to effectively mitigate the resonance under the harmonic basal ***,the time-history analysis method is used to verify the effectiveness of the traditional pendulum tuned mass damper(PTMD)and the novel PS-TMD device,and the results indicate that the vibration attenuation performance of the PS-TMD is better than the *** addition,the PS-TMD avoids the nonlinear effect due to the large oscillation angle,and has the potential to dissipate hysteretic energy under seismic excitation.

关键词： wind turbine tower prestressed tuned mass damper vibration control seismic excitation numerical simulation

Zero Dissipation Limit to Rarefaction Waves for the p-System

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Acta Mathematica Sinica,English Series 2005年第5期21卷 1229-1240页

作者： hui Ying wang Center of Mathematical Science Zhejiang University Hangzhou 310027 P. R. China

We study the zero-dissipation problem for a one-dimensional model system for the isentropic flow of a compressible viscous gas, the so-called p-system with viscosity. When the solution of the inviscid problem is a rarefaction wave with finite strength, there exists unique solution to the viscous problem with the same initial data which converges to the given inviscid solution as c goes to zero. The proof consists of a scaling argument and elementary energy analysis, based on the underlying wave structure.

关键词： Zero dissipation problem p-system Centered rarefaction wave

The validity of carbon emission trading policies:Evidence from a quasi-natural experiment in China

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Advances in Climate Change Research 2020年第2期11卷 102-109页

作者： DONG Zhi-Qing wang hui wang Shi-Xiang wang Lin-hui Faculty of Economics and Management East China Normal UniversityShanghai200241China School of Statistics Jilin University of Finance and EconomicsJilin130117China

This study focuses on the validity of carbon emission trading policies(CETP).CETP aims to adjusting the consumption structure of clean energy and promoting the transformation of green technology to achieve regional CO2 and SO2 *** difference-in-difference(DID)and spatial panel model,we estimated the abatement effect of CETP,the influence mechanism of regional CO2 and SO2 policies,environmental and economic compatibility with provincial panel data in China from 2005 to *** results show that the CETP can effectively decrease regional CO2 and SO2 emissions in pilot areas by 19.1%and 37.0%respectively when considering spatial correlation of CO2 and SO2 *** 2014 to 2017,the values of CO2 reduction effect are−0.139,−0.146,−0.187 and−0.206 respectively,indicating the abatement effect increases *** can promote 6.1%of the ratio of clean energy consumption and 4.6%of the rate of green *** addition,further benefit analysis shows that CETP can improve 12.4%of regional economic output and residents'health by reducing regional CO2 and SO2 emissions,and effectively benefit high-quality economic growth.

关键词： Carbon emission trading Clean energy Green technology High-quality economic growth

Light people:Nobel Laureate *** Betzig

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Light(Science & Applications) 2023年第9期12卷 1718-1726页

作者： hui wang Cun Yu Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of Sciences130033ChangchunChina

Super-resolution microscopy illuminated the hazy molecular world like a beacon,bringing significant changes to the fields of biology,optics and *** Betzig,who shared the 2014 Nobel Prize of Chemistry with Stefan Hell and William Moerner,is one of the inventors of this fantastic scientific *** originally on near field optics,*** made a series of stunning achievements at Bell Labs before turning *** he quit,seemingly at the top of his game,to become a hands-on dad and joined the machinery ***,he missed science so much that he made a comeback and wowed everyone instantly with his work.

关键词： optics turning instant

Light People:Elizabeth Rogan

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Light(Science & Applications) 2022年第2期11卷 138-144页

作者： hui wang Cun Yu Department of International Cooperation Changchun Institute of OpticsFine Mechanics and PhysicsChinese Academy of Sciences3888 Dong Nan Hu RoadChangchun 130033China

Throughout history,there have been many outstanding women whose achievements continue to impress and amaze us *** example,in the field of science,Madame Marie Curie was the first woman Nobel Prize winner and the only person to be awarded a Nobel Prize in two scientific *** China,Tu Youyou is a Nobel laureate who discovered artemisinin and dihydroartemisinin,used to treat malaria,a breakthrough in twentiethcentury tropical medicine,saving millions of lives around the *** such as Angela Ahrendts,a former fashion executive who helped revitalize Apple,Inc.,and Sheryl Sandberg,Chief Operating Officer of Meta Platforms(formerly Facebook),are recognized as two of the world’s most influential business ***,more than ever,women are at the forefront of developments in optics and photonics research and *** of those leaders is Elizabeth Rogan,CEO of Optica(formerly the Optical Society and the Optical Society of America.)As the executive in charge of an organization devoted to promoting the generation,application,archiving,and dissemination of knowledge in optics and photonics worldwide,*** has successfully expanded the depth and breadth of Optica’s technical and global *** education and expertise are in industry,finance,and *** utilizes these skills in partnership with a large and technically diverse group of *** and staff *** the efforts of these many talented people with a unity of purpose has proven to be a highly effective approach for Rogan and the association she has led for nearly two *** is a strong advocate for *** instance,the association’s“Faces of Optica”campaign features a wide range of accomplished women in research and *** she was an enthusiastic participant in the“Rose in Science,”which celebrates the extraordinary accomplishments of women *** Special Correspondents interviewed Elizabeth Rogan about Optica’s legacy,culture,

关键词： finance dents utilize

Rogue waves for the(2+1)-dimensional Myrzakulov–Lakshmanan-Ⅳ equation on a periodic background

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Communications in Theoretical Physics 2024年第4期76卷 32-42页

作者： Xiao-hui wang Zhaqilao College of Mathematics Science Inner Mongolia Normal UniversityHohhot 010022China Laboratory of Infinite-dimensional Hamiltonian System and Its algorithm Application Hohhot 010022China Center for Applied Mathematical Science Inner MongoliaHohhot 010022China

In this paper, the rogue wave solutions of the(2+1)-dimensional Myrzakulov–Lakshmanan(ML)-Ⅳ equation, which is described by five component nonlinear evolution equations, are studied on a periodic background. By using the Jacobian elliptic function expansion method, the Darboux transformation(DT) method and the nonlinearization of the Lax pair, two kinds of rogue wave solutions which are expressed by Jacobian elliptic functions dn and cn, are *** relationship between these five kinds of potential is summarized systematically. Firstly, the periodic rogue wave solution of one potential is obtained, and then the periodic rogue wave solutions of the other four potentials are obtained directly. The solutions we find present the dynamic phenomena of higher-order nonlinear wave equations.

关键词： rogue waves on a periodic background (2+1)-dimensional Myrzakulov-Lakshmanan-IV equation Darboux transformation Jacobian elliptic function

A Zone Plate as a Tunable Terahertz Filter

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Chinese Physics Letters 2010年第6期27卷 97-99页

作者： FENG hui wang Li Laboratory of Optical Physics Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing 100190

A broadband tunable terahertz filter based on a zone plate is demonstrated in our terahertz time domain spec- trometer. The central bandpass frequency covers the whole spectral range of the terahertz wave emitted from a ZnTe emitter, from 0.5 THz to 2.5 THz, and can be tuned continuously by simply moving the zone plate along the terahertz beam path. The peak transmission is about 40% and the bandwidth varies from 0.16 THz to 0.25 THz at different bandpass frequencies when the aperture size is kept constant.

关键词： Zoning A Zone Plate Tunable Terabertz Filter