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Electroacupuncture promotes the recovery of motor neuron function in the anterior horn of the injured spinal cord

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Neural Regeneration Research 2015年第12期10卷 2033-2039页

作者： Jian-hui Yang Jian-guo Lv hui Wang hui-yong nie Rehabilitation Center First Affiliated Hospital of Health Science CenterXi’an Jiaotong University

Acupuncture has been shown to lessen the inflammatory reaction after acute spinal cord injury and reduce secondary ***,the mechanism of action remains *** this study,a rat model of spinal cord injury was established by compressing the T8-9 segments using a modified Nystrom ***-four hours after injury,Zusanli（ST36）,Xuanzhong（GB39）,Futu（ST32）and Sanyinjiao（SP6）were stimulated with *** with spinal cord injury alone were used as *** 2,4 and 6 weeks after injury,acetylcholinesterase（ACh E）activity at the site of injury,the number of medium and large neurons in the spinal cord anterior horn,glial cell line-derived neurotrophic factor（GDNF）m RNA expression,and Basso,Beattie and Bresnahan locomotor rating scale scores were greater in the electroacupuncture group compared with the control *** results demonstrate that electroacupuncture increases ACh E activity,up-regulates GDNF m RNA expression,and promotes the recovery of motor neuron function in the anterior horn after spinal cord injury.

关键词： nerve regeneration spinal cord injury electroacupuncture spine injury secondaryinjury acupoint motor neurons acetylcholinesterase glial cell line-derived neurotrophic factor inclined board test Basso, Beattie and Bresnahan locomotor rating scale functional recovery neuralregeneration

Effects of 7-methylxanthine on form-deprivation myopia in pigmented rabbits

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International Journal of Ophthalmology(English edition) 2012年第2期5卷 133-137页

作者： Hao-hui nie, Dong-Mei Cui State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center SunYat-sen University Guangzhou 510060 Guangdong Province China Trier Research Laboratories Tingskiftevej 6 DK-2900 Hellerup Denmark

AIM: To determine the effect of 7-methylxanthine (7-MX) on the posterior sclera of form-deprivation myopia (FDM) in pigmented rabbits. METHODS: Sixteen pigmented rabbits were monocularly deprived (MD) by suturing the right eyelids after natural eye opening (ten-day old) for a period of 30 days. Two groups of pigmented rabbits were fed either 7-MX (30 mg per kg body weight; n=8) or vehicle control (saline equal volume with 7-MX; n=8). Ocular refractions, axial lengths and body weights were measured at the start and the end of the experiment 30 days later. Electron microscopy was used to measure and determine the collagen fibril diameters in the posterior pole of sclera. RESULTS: In vehicle control MD pigmented rabbits, 30 days of MD produced -1.10D+/- 0.78D of myopia and the axial length increased 0.51mm+/- 0.09mm. In MD pigmented rabbits fed with 7-MX, 30 days of MD induced only -0.21D+/- 0.11D of myopia and the axial length increased 0.07mm+/- 0.10mm. There was significant change in axial length of vehicle control MD pigmented rabbits (13.11mm +/- 0.19mm versus 12.60mm+/- 0.06mm; P =0.03). The changes in refraction and axial length of two MD groups' contalateral eyes during the 30 days were not significantly different (2.75D+/- 0.27D versus 2.75D 0.35D, P>0.05; 12.60mm+/- 0.06mm versus 12.45mm +/- 0.14mm, P >0.05). The weights of the two groups pigmented rabbits had no significant changes (187g+/- 22.1g versus 189g+/- 19.3g, P>0.05). The diameter cif scleral collagen fibers increased in both eyes of 7-MX treated pigmented rabbits. There was significant difference in collagen fibril diameters of inner layer (111.34nm+/- 28.30nm versus 94.80nm +/- 27.52nm, P =0.002) and outer layer (167.92nm +/- 55.82nm versus 144.04nm +/- 47.02nm P =0.016) in the posterior sclera between the myopic eyes of vehicle control MD group and contralateral eyes of 7-MX treated MD group. CONCLUSION: 7-MX appears to prevent FDM in pigmented rabbits by remodeling the posterior sclera.

关键词： 7-methylxanthine pigmented rabbits myopia

Microstructure and Dynamic Compression Properties of PM Al6061/B_4C Composite

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Acta Metallurgica Sinica(English Letters) 2015年第10期28卷 1214-1221页

作者： Hong-Sheng Chen Wen-Xian Wang hui-hui nie Yu-Li Li Qiao-Chu Wu Peng Zhang College of Materials Science and Engineering Taiyuan University of Technology Key Laboratory of Interface Science and Engineering in Advanced Materials Ministry of Education Taiyuan University of Technology Shanxi Key Laboratory of Advanced Magnesium-Based Materials Taiyuan University of Technology

Aluminum 6061 matrix composite reinforced by 35 wt% B4 C particle was fabricated by power metallurgy method. Then, the as-deformed composite was tested by quasi-static（0.001 s-1） and dynamic（760-1150 s-1） compression experiments. The Johnson-Cook plasticity model was employed to model the flow behavior. The damage mechanism of composite was analyzed through the microstructure observations. The results showed that the B4 C particles exhibited uniform distribution and no deleterious reaction product Al4C3 was found in the composite. Al6061/B4 C composite showed high yield strength, moderate strain rate sensitivity and strain hardening under the dynamic loading, and a constitutive model under dynamic compression was established based on Johnson-Cook model, and accorded well with experimental results. The microstructure damage was dominated by particle fracture and interface debonding, and the dislocation was observed in the composite at a higher strain rate.

关键词： Power metallurgy Dynamic compression Johnson-Cook model AI6061/B4C composite

Green revolution in electronic displays expected to ease energy and health crises

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Light(Science & Applications) 2021年第3期10卷 327-340页

作者： Yuyang Wang hui nie Jinsong Han Yaxun An Yu-Mo Zhang Sean Xiao-An Zhang State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012China Department of Chemistry and Biochemistry University of CaliforniaSanta BarbaraSanta BarbaraCalifornia 93106USA State Grid Heilongjiang Electric Power Co. LtdHeihe Power Supply CompanyHeihe 164300China Jiaxing IrS Display Technology Co. LtdJiashan 314113China

The technological revolution of long-awaited energy-saving and vision-friendly displays represented by bistable display technology is *** we discuss methods,challenges,and opportunities for implementing bistable displays in terms of molecular design,device structure,further expansion,and required criteria,hopefully benefiting the light-related community.

关键词： energy electronic revolution

Characterization of suspended solids and particle-bound heavy metals in a first flush of highway runoff

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第11期9卷 1567-1575页

作者： Fa-hui nie Tian LI Hai-feng YAO Man FENG Guang-kai ZHANG State Key Laboratory of Pollution Control and Resource Reuse Tongji University Shanghai 200092 China Institute of Environment Engineering Research East China Jiaotong University Nanchang 330013 China

To investigate the dynamic characteristics of total suspended solids (TSS) and their particle-bound heavy metals in a first flush, the runoff sampling together with its flow rate measuring was conducted for three rainfall events at outfalls of highway in Shanghai from June to September 2007. Field samples were analyzed to determine the concentrations of TSS and particle-bound heavy metals, such as Zn, Pb, and Cu. Results show that the wash off behavior of TSS under varying runoff rate condition can be explained by different antecedent dry weather period (ADWP). Contribution of fine fraction (45 μm). When the runoff flow increased obviously, a significant contribution of the coarse fraction was observed for a certain rainfall events with long antecedent dry weather condition. The changes of total metals concentration and particle-bound metal concentrations were strongly dependent on the TSS variation. TSS was generally well correlated with most particulate-bound heavy metals. Of the heavy metals, the concentration of Zn was found considerably high and that of Pb was significantly low at North Zhongshan 2 Road, in Shanghai, China, but they are still within the range reported in the literature. Fluctuation of heavy metal contents in the coarse fraction during a first flush period was more significant compared with that in the fine fraction. The results will assist in the development of effective control strategies to minimize heavy metals and solids in highway runoff.

关键词： Heavy metals Highway runoff First flush Suspended solids (SS)

Establishment and management of neurosurgery emergency observation ward during the COVID‑19 epidemic period

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Journal of Integrative Nursing 2020年第3期2卷 138-143页

作者： hui‑Ting nie Zong‑Ying ZOU hui ZHANG Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

During the COVID‑19 epidemic period,the front‑line antiepidemic departments have attracted much ***,to meet people’s daily needs for the diagnosis and treatment,emergency department and intensive care unit are also the focus of work to control the source of infection,cut off the transmission route,and reduce the risk of novel coronavirus transmission while treating *** order to further strengthen the management,our department of neurosurgery took active measures in the emergency treatment for patients and summarized the coping strategies and relevant experience from the aspects of establishment of emergency observation wards,medical staff management,patients and family management,daily environment and object surface disinfection management,material management,and nursing quality management,hoping to provide reference for the nursing management of emergency wards after the outbreak of public health emergencies.

关键词： COVID‑19 neurosurgery emergency observation wards nursing management public health emergencies

An analytical approach to modeling stress-strain relationship of particle-reinforced metal matrix composites

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Rare Metals 2022年第11期41卷 3903-3910页

作者： Zhao-Bing Xiang Jun-hui nie Shao-Hua Wei Tao Zuo Jian-Zhong Fan National Engineering Technology Research Center for Nonferrous Metals Composites General Research Institute for Nonferrous MetalsBeijing100088China

An analytical model was established to simulate the stress-strain curves of particle-reinforced metal matrix composites by the classical stress equilibrium equation and secant modulus method,where particle cracking and matrix tearing were taken into *** stress-strain curves of the composites predicted by the model fit the experimental curves very *** stressstrain relationship of the matrix affected by the particles is predicted exactly,and it is found that the yield stress of the matrix is influenced obviously by the particle *** yield strength of the composites is also predicted by the model,and the results fit the experimental data very well.

关键词： Strengthening mechanism Yield strength Particle fracture Matrix stress-strain curve

Aluminum matrix composites reinforced by molybdenum-coated carbon nanotubes

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International Journal of Minerals,Metallurgy and Materials 2011年第6期18卷 695-702页

作者： Jun-hui nie Cheng-chang Jia Na Shi Ya-feng Zhang Yi Li XianJia School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China

To extend the application of carbon nanotubes （CNTs） and explore novel aluminum matrix composites,CNTs were coated by molybdenum layers using metal organic chemical vapor deposition,and then Mo-coated CNT （Mo-CNT）/Al composites were prepared by the combination processes of powder mixing and spark plasma *** influences of powder mixing and Mo-CNT content on the mechanical properties and electrical conductivity of the composites were *** results show that magnetic stirring is better than mechanical milling for mixing the Mo-CNTs and Al *** electrical conductivity of the composites decreases with increasing Mo-CNT *** the Mo-CNT content is 0.5wt%,the tensile strength and hardness of Mo-CNT/Al reach their maximum *** tensile strength of 0.5wt% Mo-CNT/Al increases by 29.9%,while the electrical conductivity only decreases by 7.1%,relative to sintered pure *** phase analysis of Mo-CNT/Al composites reveals that there is no formation of Al carbide in the composites.

关键词： carbon nanotubes aluminum matrix composites molybdenum layer mechanical properties electrical conductivity

Synthesis and Properties of Hydroxide Conductive Polymers Carrying Dense Aromatic Side-chain Quaternary Ammonium Groups

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Chinese Journal of Polymer Science 2017年第7期35卷 823-836页

作者： Guang-hui nie Wen-Jun Wu Xi Yue Shi-jun Liao 李秀华 School of Chemistry&Chemical Engineering South China University of TechnologyGuangzhou 510641China The Key Laboratory of Fuel Cell Technology of Guangdong Province South China University of TechnologyGuangzhou 510641China

A series of hydroxide conductive polymers QTBMs carrying dense aromatic side-chain quaternary ammonium groups has been synthesized by using a new monomer of 3,3＇-di（3＂,5＂-dimethylphenyl）-4,4＇-difluorodiphenyl sulfone and other commercial monomers via polycondensation reaction, and subsequent bromination, quaternization and alkalization. The chemical structures of the ionomers were confirmed by 1H- and 13C-NMR spectroscopy. Water uptake, swelling ratio, hydroxide conductivity, the number of bonded water per ammonium group （A）, volumetric ion exchange capacity （IECvwet）, mechanical and thermal properties, and chemical stability were systematically evaluated for the series of QTBMs membranes. QTBMs showed IECs ranging from 1.02 meq·g-1 to 2.11 meq·g-1; in particular, QTBM-60 membrane with the highest IEC （2.11 meq·g-1） had very high hydroxide ion conductivity of 131.9 mS·cm-1 at 80 ℃, which was attributed to the well assembled nano-channels with distinct phase separation evidenced by small-angle X-ray scattering （SAXS）. It was found that the hydrated QTBMs membranes were mechanically stable with moderate water uptakes and swelling ratios, high chemical stability under the harsh alkaline conditions. This work provides a facile way to prepare anion exchange membranes （AEMs） with high performances for the application in alkaline fuel cells.

关键词： Aromatic side-chain quaternary ammonium Bromination Alkaline anion exchange membrane Poly(aryleneether sulfone)s