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Nuclear Science and Techniques 2024年第8期35卷 101-113页

作者： hui‑yin shen Jing‑Long Zhang Jie Zhang Jian‑Hang Zhou College of Nuclear Technology and Automation Engineering Chengdu University of TechnologyChengdu 610059China Southwestern Institute of Physics P.O.Box 432Chengdu 610041China

Fast neutron flux measurements with high count rates and high time resolution have important applications in equipment such as *** this study,real-time neutron and gamma discrimination was implemented on a self-developed 500-Msps,12-bit digitizer,and the neutron and gamma spectra were calculated directly on an FPGA.A fast neutron flux measurement system with BC-501A and EJ-309 liquid scintillator detectors was developed and a fast neutron measurement experiment was successfully performed on the HL-2 M tokamak at the Southwestern Institute of Physics,*** experimental results demonstrated that the system obtained the neutron and gamma spectra with a time accuracy of 1 *** count rates of up to 1 Mcps,the figure of merit was greater than 1.05 for energies between 50 keV and 2.8 MeV.

关键词： Neutron-gamma discrimination Liquid scintillation detector Real-time spectrum analyzer

Mpox(formerly monkeypox):pathogenesis,prevention,and treatment

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Signal Transduction and Targeted Therapy 2024年第1期9卷 234-248页

作者： Junjie Lu hui Xing Chunhua Wang Mengjun Tang Changcheng Wu Fan Ye Lijuan yin Yang Yang Wenjie Tan Liang shen Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and ScienceHubei ProvinceXiangyang 441021China NHC Key Laboratory of Biosafety National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China College of Biotechnology Tianjin University of Science&TechnologyTianjin 300457China shenzhen Key Laboratory of Pathogen and Immunity National Clinical Research Center for infectious diseaseState Key Discipline of Infectious DiseaseShenzhen Third People’s HospitalSecond Hospital Affiliated to Southern University of Science and TechnologyShenzhen 518112China

In 2022,a global outbreak of Mpox(formerly monkeypox)occurred in various countries across Europe and America and rapidly spread to more than 100 countries and *** World Health Organization declared the outbreak to be a public health emergency of international concern due to the rapid spread of the Mpox ***,nations intensified their efforts to explore treatment strategies aimed at combating the infection and its ***,the available therapeutic options for Mpox virus infection remain *** far,only a few numbers of antiviral compounds have been approved by regulatory *** the high mutability of the Mpox virus,certain mutant strains have shown resistance to existing pharmaceutical *** highlights the urgent need to develop novel antiviral drugs that can combat both drug resistance and the potential threat of ***,there is a lack of comprehensive literature on the pathophysiology and treatment of *** address this issue,we conducted a review covering the physiological and pathological processes of Mpox infection,summarizing the latest progress of anti-Mpox *** analysis encompasses approved drugs currently employed in clinical settings,as well as newly identified small-molecule compounds and antibody drugs displaying potential antiviral efficacy against ***,we have gained valuable insights from the process of Mpox drug development,including strategies for repurposing drugs,the discovery of drug targets driven by artificial intelligence,and preclinical drug *** purpose of this review is to provide readers with a comprehensive overview of the current knowledge on Mpox.

关键词： prevention treatment intensified

A universal multifunctional dual cation doping strategy towards stabilized ultra-high nickel cobalt-free lithium layered oxide cathode

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Journal of Energy Chemistry 2024年第8期95卷 296-305,I0007页

作者： Yabin shen Dongming yin Limin Wang Gang Huang Yong Cheng Henan Institute of Advanced Technology Zhengzhou UniversityZhengzhou 450002HenanChina State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022JilinChina

Ultra-high nickel cobalt-free lithium layered oxides are promising cathode material for lithium-ion batteries(LIBs)because of their relatively high capacity and low ***,the high nickel content would induce bulk structure degradation and interfacial environment deterioration,and the absence of Co element reduces the lithium diffusion kinetics,severely limiting the performance liberation of this kind of ***,a multifunctional Ti/Zr dual cation co-doping strategy has been employed to improve the lithium storage performance of LiNi_(0.9)Mn_(0.1)O_(2)(NM91)*** the one hand,the Ti/Zr co-doping weakens the Li^(+)/Ni^(2+)mixing through magnetic interactions due to the inexistence of unpaired electrons for Ti^(4+)and Zr^(4+),increasing the lithium diffusion rate and suppressing the harmful coexistence of H1 and H2 *** the other hand,they enhance the lattice oxygen stability because of the strong Ti-O and Zr-O bonds,inhibiting the undesired H3 phase transition and lattice oxygen loss,improving the bulk structure and cathode-electrolyte interface *** a result,the Ti/Zr co-doped NM91(NMTZ)exhibits a 91.2%capacity retention rate after 100 cycles,while that of NM91 is only82.9%.Also,the NMTZ displays better rate performance than NM91 with output capacities of 115 and93 mA h g^(-1)at a high current density of 5 C,***,the designed NMTZ could enable the full battery to deliver an energy density up to 263 W h kg^(-1),making the ultra-high nickel cobaltfree lithium layered oxide cathode closer to practical applications.

关键词： Lithium-ion battery Ultra-high nickel cobalt-free cathode Ti/Zr co-doping Li^(+)/Ni^(2+)mixing Lattice oxygen stability

Effect of solvent on the initiation mechanism of living anionic polymerization of styrene:A computational study

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Chinese Journal of Chemical Engineering 2024年第5期69卷 135-142页

作者： shen Li yin-Ning Zhou Zhong-Xin Liu Zheng-Hong Luo School of Chemical Engineering and Technology Hainan UniversityHaikou 570228China Department of Chemical Engineering School of Chemistry and Chemical EngineeringState Key Laboratory of Metal Matrix CompositesShanghai Jiao Tong UniversityShanghai 200240China

For living anionic polymerization(LAP),solvent has a great influence on both reaction mechanism and *** this work,by using the classical butyl lithium-styrene polymerization as a model system,the effect of solvent on the mechanism and kinetics of LAP was revealed through a strategy combining density functional theory(DFT)calculations and kinetic *** terms of mechanism,it is found that the stronger the solvent polarity,the more electrons transfer from initiator to solvent through detailed energy decomposition analysis of electrostatic interactions between initiator and solvent ***,we also found that the stronger the solvent polarity,the higher the monomer initiation energy barrier and the smaller the initiation rate ***,initiation is more favorable at lower temperatures based on the calculated results ofΔG_(TS).Finally,the kinetic characteristics in different solvents were further examined by kinetic *** is found that in benzene and n-pentane,the polymerization rate exhibits first-order ***,slow initiation and fast propagation were observed in tetrahydrofuran(THF)due to the slow free ion formation rate,leading to a deviation from first-order kinetics.

关键词： Living anionic polymerization Solvent effect Reaction kinetics Computational chemistry Mathematical modeling Kinetic modeling

Grain boundary engineering for enhancing intergranular damage resistance of ferritic/martensitic steel P92

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Nuclear Science and Techniques 2024年第5期35卷 186-199页

作者： Lei Peng Shang-Ming Chen Jing-Yi Shi Yong-Jie Sun Yi-Fei Liu yin-Zhong shen Hong-Ya He hui-Juan Wang Jie Tian State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China School of Materials Engineering Shanghai University of Engineering Science333 Long Teng RoadShanghai 201620China Experimental Center of Engineering and Material Science University of Science and Technology of ChinaHefei 230026China

Ferritic/martensitic(F/M)steel is widely used as a structural material in thermal and nuclear power ***,it is susceptible to intergranular damage,which is a critical issue,under service *** this study,to improve the resistance to intergranular damage of F/M steel,a thermomechanical process(TMP)was employed to achieve a grain boundary engineering(GBE)microstructure in F/M steel *** TMP,including cold-rolling thickness reduction of 6%,9%,and 12%,followed by austenitization at 1323 K for 40 min and tempering at 1053 K for 45 min,was applied to the as-received(AR)P92 *** prior austenite grain(PAG)size,prior austenite grain boundary character distribution(GBCD),and connectivity of prior austenite grain boundaries(PAGBs)were *** to the AR specimen,the PAG size did not change *** fraction of coincident site lattice boundaries(CSLBs,3≤Σ≤29)and Σ3^(n) boundaries along PAGBs decreased with increasing reduction ratio because the recrystallization fraction increased with increasing reduction *** PAGB connectivity of the 6%deformed specimen slightly deteriorated compared with that of the AR ***,potentiodynamic polarization studies revealed that the intergranular damage resistance of the studied steel could be improved by increasing the fraction of CSLBs along the PAGBs,indicating that the TMP,which involves low deformation,could enhance the intergranular damage resistance.

关键词： Grain boundary engineering Ferritic/martensitic steel Prior austenite grain boundary character distribution Grain boundary connectivity Intergranular damage resistance

Research on a Monte Carlo global variance reduction method based on an automatic importance sampling method

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Nuclear Science and Techniques 2024年第5期35卷 200-215页

作者： Yi-sheng Hao Zhen Wu shen-shen Gao Rui Qiu hui Zhang Jun-Li Li Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Particle and Radiation Imaging of Ministry of Education Beijing 100084China Nuctech Company Limited Beijing 100084China

Global variance reduction is a bottleneck in Monte Carlo shielding *** global variance reduction problem requires that the statistical error of the entire space is *** study proposed a grid-AIS method for the global variance reduction problem based on the AIS method,which was implemented in the Monte Carlo program *** proposed method was validated using the VENUS-Ⅲ international benchmark problem and a self-shielding calculation *** results from the VENUS-Ⅲ benchmark problem showed that the grid-AIS method achieved a significant reduction in the variance of the statistical errors of the MESH grids,decreasing from 1.08×10^(-2) to 3.84×10^(-3),representing a 64.00% *** demonstrates that the grid-AIS method is effective in addressing global *** results of the selfshielding calculation demonstrate that the grid-AIS method produced accurate computational ***,the grid-AIS method exhibited a computational efficiency approximately one order of magnitude higher than that of the AIS method and approximately two orders of magnitude higher than that of the conventional Monte Carlo method.

关键词： Monte Carlo Global variance reduction Reactor shielding Automatic importance sampling

Wood use and forest management by Neolithic millet farmers at the Xinglong site,northern China

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Science China Earth Sciences 2024年第6期67卷 1910-1921页

作者： hui shen Zhenwei QIU Keliang ZHAO Xinying ZHOU Xiaoqiang LI Key Laboratory of Vertebrate Evolution and Human Origins Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijing 100044China National Museum of China Beijing 100006China University of Chinese Academy of Sciences Beijing 100049China

The origin and development of agriculture and its relationship with climate change are hotly debated topics among environmental *** this study,we analyzed wood charcoal materials from the Neolithic Xinglong site in northern China in order to understand the woody vegetation around the site and how early millet farmers shaped local *** results suggest that the area around the Xinglong sites during 8700-7000 yr BP was primarily woodlands,including Prunus sibirica shrubs,Ulmus and Acer forests,and Populus stands near *** 8000 to 7000 yr BP,the warm and humid climate probably contributed to the expansion of Acer,Rhamnus,and Juniperus,and may have facilitated the development of early millet *** these ancient wood fragments that we studied,the high percent of Prunus charcoal appears to indicate an abundance of fruit trees,which might have constituted the main component of local ***,the wood taxa illustrate the existence of a variety of ecological habitats,and it is logical to assume that people made full use of the locally available wood ***,Populus and Ulmus were the dominant sources of *** results of tree-ring curvature analyses indicate that people mainly collected trunks or large branches of Ulmus,Populus,Acer,and Juniperus *** interpret the increasing use of Prunus twigs and the declining percentage of Prunus charcoal in the period between 8000-7000 yr BP as indicating that people started to protect and manage wild fruit *** may have started pruning to acquire more food resources as part of the cultural responses and adaptation strategies employed by these early millet cultivators.

关键词： Xinglong site Wood charcoal Wood use Woodland management

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A review of traffic behaviour and intelligent driving at roundabouts based on a microscopic perspective

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Transportation Safety and Environment 2024年第3期6卷 1-16页

作者： Haobin Jiang Qingyuan shen Aoxue Li Chenhui yin Automotive Engineering Research Institute Jiangsu UniversityZhenjiang 212013JiangsuChina School of Automotive and Traffic Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina

The contradiction between increasing traffic and the relatively poor roundabout infrastructure is getting *** control and optimization of the macroscopic traffic flow needs to be improved to resolve congestion and safety problems at roundabouts and the connected road *** order to better understand the gaps and trends in this field,we have systematically reviewed the main research and developments in traffic phenomena,driving behaviour,autonomous vehicles(AVs),intelligent connected vehicles and real vehicle trajectory data sets at *** study is based on 388 papers about roundabouts,selected through a comprehensive literature *** review demonstrates that based on a microscopic perspective,sensing,prediction,decision-making,planning and control aspects of AVs and intelligent connected vehicles can be designed and optimized to fundamentally and significantly improve traffic capacity and driving safety at ***,the generation mechanism of traffic conflicts among traffic participants at roundabouts is complex,which is a tremendous challenge for the systematic design of ***,based on naturalistic driving data and machine learning theory,it is an important research direction to build driver models by learning and imitating human driver decision-making and driving behaviours.

关键词： autonomous vehicles driving behaviour naturalistic driving data roundabout traffic capacity

Effect of moxibustion on expression profile of miRNAs in Tripterygium glycoside-induced decreased ovarian reserve

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Journal of Traditional Chinese Medicine 2024年第4期44卷 745-752页

作者： shen Jie yin Yaoli LI Hongxiao LU Ge ZHU Yaoyao QIN Yantong JIN Xun CHENG Jie shen Meihong College of Acupuncture and Tuina Nanjing University of Chinese Medicine

OBJECTIVE: To explore the possible regulatory mechanism of microRNA(miRNA) in moxibustion treatment for decreased ovarian reserve(DOR). METHODS: The DOR model was constructed by intragastrical Tripterygium glycoside suspension administration, and moxibustion therapy was simultaneously given. The morphological ovarian changes were observed by hematoxylin and eosin staining. The miRNA expression profile was detected by RNA sequencing, and bioinformatics analysis was performed. Cytoscape software 3.6.1 was used to establish a regulatory network and differentially expressed miRNAs were verified by reverse transcription quantitative polymerase chain reaction(RT-qPCR). RESULTS: Decreased number of mature follicles, increased atresia follicles, and abnormal granulosa cell morphology were observed in the model group compared with the control group. The moxibustion group demonstrated increased mature follicles, decreased atretic follicles, and significantly decreased abnormal morphology of granulosa cells compared with the model group. Additionally, RNA sequencing results manifested significantly up-regulated miRNA expressions(miR-92b-3p, miR-26-5p＿R + 1＿1ss10TC, miR-206-3p, miR-9993b-3p＿1ss6GA, miR-7857-3p＿R-1, miR-219a-2-3p＿1ss10GC, miR-3968-p5＿1ss10AT, and PC-5p-6478＿1795) and down-regulated miR-664-2-5p＿R + 1 in the model group, compared with the control group, and the moxibustion group reversed abnormal disorder levels of these miRNAs. Moreover, these differentially expressed miRNAs were mainly involved in the phosphatidylinositol-3-kinase/protein kinase B signaling pathway and nuclear factor erythropoietin-2-related factor 2/heme oxygenase 1 signaling pathway. Finally, network and RT-qPCR verification revealed miR-9993b-3p＿1ss6GA as the most critical miRNA. CONCLUSION: This experiment proved the effectiveness of moxibustion in improving the ovarian reserve of rats by regulating miRNA expression, especially miR-9993b-3p＿1ss6GA.

关键词： mechanics microRNAs moxibustion ovarian reserve

Vibration Suppression for Active Magnetic Bearings Using Adaptive Filter with Iterative Search Algorithm

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CES Transactions on Electrical Machines and Systems 2024年第1期8卷 61-71页

作者： Jin-hui Ye Dan Shi Yue-sheng Qi Jin-hui Gao Jian-Xin shen IEEE Department of Electrical Engineering Zhejiang UniversityHangzhou 310027China CES and IEEE

Active Magnetic Bearing(AMB) is a kind of electromagnetic support that makes the rotor movement frictionless and can suppress rotor vibration by controlling the magnetic force. The most common approach to restrain the rotor vibration in AMBs is to adopt a notch filter or adaptive filter in the AMB controller. However, these methods cannot obtain the precise amplitude and phase of the compensation current. Thus, they are not so effective in terms of suppressing the vibrations of the fundamental and other harmonic orders over the whole speed range. To improve the vibration suppression performance of AMBs,an adaptive filter based on Least Mean Square(LMS) is applied to extract the vibration signals from the rotor displacement signal. An Iterative Search Algorithm(ISA) is proposed in this paper to obtain the corresponding relationship between the compensation current and vibration signals. The ISA is responsible for searching the compensating amplitude and shifting phase online for the LMS filter, enabling the AMB controller to generate the corresponding compensation force for vibration suppression. The results of ISA are recorded to suppress vibration using the Look-Up Table(LUT) in variable speed range. Comprehensive simulations and experimental validations are carried out in fixed and variable speed range, and the results demonstrate that by employing the ISA, vibrations of the fundamental and other harmonic orders are suppressed effectively.

关键词： Active Magnetic Bearing(AMB) Adaptive filter Iterative search algorithm Least mean square(LMS) Vibration suppression