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基于泥鳅体表的水稻直播机仿生滑板设计与试验

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吉林大学学报（工学版） 2024年第5期54卷 1482-1492页

作者：张国忠丁凯权李正博陈龙唐楠锐刘婉茹黄海东周勇王洪昌华中农业大学工学院武汉430070 农业农村部长江中下游农业装备重点实验室武汉430070

针对水稻直播机滑板在扰动饱和水田环境中黏附重和阻力大的问题,显微观测得到泥鳅体表非光滑表面;利用Fluent软件进行仿真分析,揭示了该非光滑表面减黏降阻的原理;采用Box-Behnken响应面法设计试验,得到沟槽非光滑表面总阻力FB与沟宽w... 详细信息

针对水稻直播机滑板在扰动饱和水田环境中黏附重和阻力大的问题,显微观测得到泥鳅体表非光滑表面;利用Fluent软件进行仿真分析,揭示了该非光滑表面减黏降阻的原理;采用Box-Behnken响应面法设计试验,得到沟槽非光滑表面总阻力FB与沟宽w、沟深h和来流速度v的回归方程,最优化分析结果表明,当w为4.5 mm、h为4mm、v为1.25 m/s时,最大减阻率达10.052%;基于最优参数试制了水稻直播机仿生滑板,开展了室内水田土槽试验,最终减阻率达10.23%。本研究可为水田触土部件减黏降阻技术开发提供新思路。

关键词：农业机械化工程泥鳅仿生非光滑表面水田土壤减黏降阻

Computational tools for plant genomics and breeding

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Science China(Life Sciences) 2024年第8期67卷 1579-1590页

作者： hai Wang Mengjiao Chen Xin Wei Rui Xia dong Pei Xuehui huang Bin Han State Key Laboratory of Maize Bio-breeding Frontiers Science Center for Molecular Design BreedingJoint International Research Laboratory of Crop Molecular BreedingNational Maize Improvement CenterCollege of Agronomy and BiotechnologyChina Agricultural UniversityBeijing 100193China Sanya Institute of China Agricultural University Sanya 572025China hainan Yazhou Bay Seed Laboratory Sanya 572025China State Key Laboratory of Tree Genetics and Breeding Key Laboratory of Tree Breeding and Cultivation of the State Forestry and Grassland AdministrationResearch Institute of ForestryChinese Academy of ForestryBeijing 100091China Shanghai Key Laboratory of Plant Molecular Sciences College of Life SciencesShanghai Normal UniversityShanghai 200234China College of Horticulture South China Agricultural UniversityGuangzhou 510640China National Center for Gene Research CAS Center for Excellence in Molecular Plant SciencesChinese Academy of SciencesShanghai 200233China

Plant genomics and crop breeding are at the intersection of biotechnology and information *** by a combination of highthroughput sequencing,molecular biology and data science,great advances have been made in omics technologies at every step along the central dogma,especially in genome assembling,genome annotation,epigenomic profiling,and transcriptome *** advances further revolutionized three directions of *** is genetic dissection of complex traits in crops,along with genomic prediction and *** second is comparative genomics and evolution,which open up new opportunities to depict the evolutionary constraints of biological sequences for deleterious variant *** third direction is the development of deep learning approaches for the rational design of biological sequences,especially proteins,for synthetic *** three directions of development serve as the foundation for a new era of crop breeding where agronomic traits are enhanced by genome design.

关键词： bioinformatics plant genomics breeding by design

Multi-systemic melioidosis in a patient with type 2 diabetes in nonendemic areas:A case report and review of literature

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World Journal of Clinical Cases 2024年第9期12卷 1669-1676页

作者： Huan-Yu Ni Ying Zhang dong-hai huang Feng Zhou Department of Endocrinology Puren HospitalWuhan University of Science and TechnologyWuhan 430080Hubei ProvinceChina School of Medicine Wuhan University of Science and TechnologyWuhan 430080Hubei ProvinceChina Department of Critical Care Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071Hubei ProvinceChina Department of Rheumatology and Immunology Puren HospitalWuhan University of Science and TechnologyWuhan 430080Hubei ProvinceChina

BACKGROUND Melioidosis,an infectious disease caused by Burkholderia pseudomallei(***),occurs endemically in Southeast Asia and Northern Australia and is a serious opportunistic infection associated with a high mortality *** SUMMARY A 58-year-old woman presented with scattered erythema on the skin of her limbs,followed by fever and *** was isolated successively from the patient’s urine,blood,and *** resonance imaging showed abscess formation involving the right forehead and the right frontal ***,abscess resection and drainage were *** patient showed no signs of relapse after 4 months of follow-up visits *** We present here a unique case of multi-systemic melioidosis that occurs in nonendemic regions in a patient who had no recent travel ***,it is critical to enhance awareness of melioidosis in non-endemic regions.

关键词： Melioidosis Burkholderia pseudomallei Endemic Diabetes Case report

城市轨道交通正交异性钢桥面板疲劳损伤系数研究

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河南城建学院学报 2024年第1期33卷 72-78页

作者：曾勇周新六向中富何孟松黄海东马虎张兴健重庆交通大学山区桥梁及隧道工程国家重点实验室重庆400074 重庆市轨道交通(集团)有限公司重庆401120

基于城市轨道交通正交异性钢桥面板疲劳性能的重要性,对国内多个城市的轨道交通的交通荷载进行了调研,发现各线路各时段的客流量差异较大,各线路的载客平均轴重与空车平均轴重的比值不同,比值为1.02~1.51。轨道交通因乘客流量带来的轴... 详细信息

基于城市轨道交通正交异性钢桥面板疲劳性能的重要性,对国内多个城市的轨道交通的交通荷载进行了调研,发现各线路各时段的客流量差异较大,各线路的载客平均轴重与空车平均轴重的比值不同,比值为1.02~1.51。轨道交通因乘客流量带来的轴重比例变化相对较小,因此每一列车都对钢桥结构的疲劳有一定影响。研究了疲劳损伤系数的组成,基于不同的应力循环次数,提出了基于列车荷载作用频次的城市轨道交通桥梁的3个疲劳损伤系数。研究结果可为城市轨道交通钢桥的疲劳设计提供参考,并为规范的修订提供技术依据,对完善城市轨道交通钢桥疲劳设计具有理论意义。

关键词：疲劳损伤系数城市轨道交通列车荷载正交异性钢桥面板

下调miR-223表达对脓毒症心肌病小鼠心肌的保护作用及机制研究

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现代生物医学进展 2024年第2期24卷 234-239,263页

作者：董玉杰王晓景阮国然任浩进陈诗阳黄海东张美春武汉科技大学医学院湖北武汉430080 武汉科技大学附属普仁医院心血管内科湖北武汉430080 武汉科技大学附属普仁医院风湿免疫科湖北武汉430080

目的:探讨下调miR-223表达对脓毒症心肌病(SCM)小鼠心肌的保护作用及其机制。方法:按随机数字表法将27只8-10周龄SPF级雄性C57BL/6小鼠分配至SCM模型(0 h,6 h,12 h,18 h,24 h)时相组、Normal组、SCM组、miR-223 antagomir NC组、miR-223... 详细信息

目的:探讨下调miR-223表达对脓毒症心肌病(SCM)小鼠心肌的保护作用及其机制。方法:按随机数字表法将27只8-10周龄SPF级雄性C57BL/6小鼠分配至SCM模型(0 h,6 h,12 h,18 h,24 h)时相组、Normal组、SCM组、miR-223 antagomir NC组、miR-223 antagomir组,每组3只。腹腔注射脂多糖(lipopolysaccharide,LPS)15 mg/kg构建SCM小鼠模型。miR-223 antagomir NC组与miR-223 antagomir组分别于建模前连续3天鼠尾静脉注射miR-223 antagomir NC、miR-223 antagomir预处理。采用反转录-聚合酶链反应(RT-PCR)研究SCM模型各个时相组小鼠心肌组织miR-223的表达情况。采用苏木素伊红(HE)染色法观察Normal组、SCM组、miR-223 antagomir NC组和miR-223 antagomir组小鼠心肌病理形态变化。采用酶联免疫吸附实验(ELISA)测定Normal组、SCM组、miR-223 antagomir NC组和miR-223 antagomir组小鼠血清cTnI、BNP、CK-MB、IL-6、IL-1β、TNF-α的含量并进行相关性分析。结果:SCM模型时相组小鼠随刺激时间延长,心肌组织miR-223表达水平逐渐升高。与Normal组比较,SCM组、miR-223 antagomir NC组、miR-223 antagomir组小鼠心肌组织出现不同程度损伤;血清心肌损伤标记物cTnI、BNP、CK-MB及炎性因子IL-6、IL-1β、TNF-α的表达水平均上升,差异具有统计学意义(P0.05);miR-223 antagomir组小鼠心肌组织病理损伤程度有所减轻,心肌损伤标记物cTnI、BNP、CK-MB及炎性因子IL-6、IL-1β、TNF-α水平下降,差异具有统计学意义(P<0.05)。相关性分析结果显示小鼠miR-223表达与心肌损伤标记物cTnI、BNP、CK-MB及炎性因子IL-6、IL-1β、TNF-α的表达呈正相关。结论:下调miR-223表达可通过减轻炎症反应对SCM小鼠心肌产生保护作用。

关键词：脓毒症脓毒症心肌病 miR-223 miRNA 炎症反应

Broncholithiasis-induced bronchial artery fistula and pulmonary artery fistula in an aged female： a case report

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Chinese Medical Journal 2010年第4期123卷 507-509页

作者： SHANG Yan BAI Chong huang hai-dong dong Yu-chao huang Yi YAO Xiao-peng LI Qiang Department of Respiratory Medicine Changhai Hospital Second Military Medical University Shanghai 200433 China

Broncholithiasis, a rare disorder of the respiratory system, is usually caused by pulmonary fungal infection and tuberculosis occurring in the early years of its victims. Pulmonary fungal infection and tuberculosis can lead to calcification of the hilar and mediastinal lymph nodes; the calcified lymph nodes erode the nearby bronchi and cause clinical and imaging abnormalities. When the calcified lymph nodes press or invade the bronchial lumens, changing the bronchial lumen shape, stimulating the mucous membrane and eroding the luminal wall, clinical manifestations of penetrating broncholithiasis, such as cough, sputum, hemoptysis, lithoptysis, recurrent pneumonia, peribronchial fistula,

关键词： broncholithiasis clinical manifestations diagnosis treatment

Energy-information trade-off induces continuous and discontinuous phase transitions in lateral predictive coding

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Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 79-85页

作者： Zhen-Ye huang Ruyi Zhou Miao huang hai-Jun Zhou Key Laboratory for Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China School of Optics and Photonics Beijing Institute of TechnologyBeijing 100081China Minjiang Collaborative Center for Theoretical Physics Minjiang UniversityFuzhou 350108China

Lateral predictive coding is a recurrent neural network that creates energy-efficient internal representations by exploiting statistical regularity in sensory ***,we analytically investigate the trade-off between information robustness and energy in a linear model of lateral predictive coding and numerically minimize a free energy *** observed several phase transitions in the synaptic weight matrix,particularly a continuous transition that breaks reciprocity and permutation symmetry and builds cyclic dominance and a discontinuous transition with the associated sudden emergence of tight balance between excitatory and inhibitory *** optimal network follows an ideal gas law over an extended temperature range and saturates the efficiency upper bound of energy *** results provide theoretical insights into the emergence and evolution of complex internal models in predictive processing systems.

关键词： predictive coding recurrent neural network phase transition internal model free energy

桌面毛细管快放电X射线实验装置电压测量系统的研究

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中国激光 2005年第7期32卷 894-898页

作者：黄东海 Kim dong-Eon 华侨大学信息科学与工程学院福建泉州362021 韩国浦项科技大学

桌面毛细管快放电X射线激光实验装置,是研究高压大电流放电直接激励X射线激光放大技术的快脉冲发生器。其特点是电压高、电流大、脉冲陡、干扰强、空间小。常规绝缘结构的高压无感电阻测量系统难以满足其高电压脉冲测量的要求。研究了... 详细信息

桌面毛细管快放电X射线激光实验装置,是研究高压大电流放电直接激励X射线激光放大技术的快脉冲发生器。其特点是电压高、电流大、脉冲陡、干扰强、空间小。常规绝缘结构的高压无感电阻测量系统难以满足其高电压脉冲测量的要求。研究了一种新型绝缘结构高压无感电阻电压测量传感器及两级分压测量系统,介绍了传感器的绝缘结构原理、测量系统的组成以及高电压测量结果,并从理论上验证和分析了测量系统的测量结果及相对误差。实验结果表明,新型绝缘结构高压无感电阻能同时具有较高电位梯度和较小电感的优点,设计的电压测量系统峰值误差小,抗干扰能力强,可以较好地满足毛细管快放电X射线激光实验装置中的高电压测量。

关键词：激光技术高电压测量电压传感器与测量系统新型绝缘结构高压无感电阻 X射线激光毛细管快放电

Design optimization of a hexapod vibration isolation system for electro-optical payload

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Chinese Journal of Aeronautics 2024年第2期37卷 330-342页

作者： Jing LI Weipeng LI Xiaoyan ZHANG hai huang School of Astronautics Beihang UniversityBeijing 100191China

The electro-optical payloads on mobile platforms generally suffer undesirable vibrations generated by maneuvers and *** vibrations are in six degrees of freedom and cause line-of-sight jitters,resulting in image blurring and loss of tracking *** this paper,a Hexapod Vibration Isolation System(HVIS)is proposed and optimized to solve this *** optimization aims to centralize and minimize the natural frequencies of HVIS,for expanding the vibration isolation bandwidth and improving the vibration isolation in the higher frequency *** that the design space for HVIS is limited and interfered with the frames of the mobile platform,a non-collision algorithm is proposed and applied in the optimization to obtain the feasible optimal *** optimization result shows that the natural frequency bandwidth has been reduced by 42.9%,and the maximum natural frequency is reduced by 30.2%.The prototypes of initial and optimal designs are manufactured and *** simulated and experimental results demonstrate the validity of the optimization,and the optimal design provides a maximum of 15 dB more isolation in rotation direction than the initial design.

关键词： Electro-optical payload Vibrations Isolation system Hexapod Optimization Non-collision design