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Preventing prolonged post-operative ileus in gastric cancer patients undergoing gastrectomy and intra-peritoneal chemotherapy

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World Journal of Gastroenterology 2005年第31期11卷 4776-4781页

作者： De-Chuan Chan Yao-Chi Liu Cheng-Jueng Chen Jyh-Cherng Yu Heng-Cheng Chu fa-Chang Chen Teng-Wei Chen huan-fa hsieh Tzu-Ming Chang Kuo-Liang Shen Division of General Surgery Tri-Service General Hospital National Defense Medical Center National Defense University Taipei Taiwan China Division of Gastroenterology and Hepatology Department of Internal Medicine Tri-Service General HospitalNational Defense Medical Center National Defense UniversityTaipei Taiwan China Department of Anesthesiology Tfi-Service General Hospital National Defense Medical Center National Defense University Taipei Taiwan China Yee-Zen General Hospital Taoyuan Taiwan China Department of Surgery Shalu Tungs' Memorial Hospital Tai-Chung Taiwan China

AIM： To assess the efficacy of metoclopramide （Met） for prevention of prolonged post-operative ileus in advanced gastric cancer patients undergoing D2 gastrectomy and intra-peritoneal chemotherapy （IPC）. METHODS： Thirty-two advanced gastric cancer patients undergoing D2 gastrectomy and IPC were allocated to two groups. Sixteen patients received Met immediately after operation （group A）, and 16 did not （group B）. Another 16 patients who underwent D2 gastrectomy without IPC were enrolled as the control group （group C）. All patients had received epidural pain control. The primary endpoints were time to first post-operative flatus and time until oral feeding with a soft diet without discomfort. Secondary endpoints were early complications during hospitalization. RESULTS： Gender, the type of resection, operating time, blood loss, tumor status and amount of narcotics were comparable in the three groups. However, the group C patients were older than those in groups A and B （67.5±17.7 vs 56.8±13.2, 57.5±11.7 years, P= 0.048）. First bowel flatus occurred after 4.35±0.93 d in group A, 4.94±1.37 d in group B, and 4.71±1.22 d in group C （P〉0.05）. Oral feeding of a sore diet was tolerated 7.21±1.92 d after operation in group A, 10.15±2.17 d in group B, and 7.53±1.35 d in group C （groups A and C vsgroup B, P〈0.05）. There was no significant difference in respect to the first flatus among the three groups. However, the time of tolerating oral intake with soft food in groups A and C patients was significantlyshorter than that in group B patients. Levels of C-reactive protein （CRP） were significantly lower in group C and there was a more prominent and prolonged response in CRP level in patients undergoing IPC. The incidence of post-operative complications was similar in the three groups except for prolonged post-operative ileus. There was no increased risk of anastomotic leakage in patients receiving Met. CONCLUSION： The results suggest that a combination of intravenous Met and epidu

关键词： Metoclopramide C-reactive protein Gastric cancer Intraperitoneal chemotherapy

Diverticulosis of the jejunum with intestinal obstruction: A case report

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World Journal of Gastroenterology 2005年第34期11卷 5416-5417页

作者： Chien-Hua Lin huan-fa hsieh Chih-Yung Yu Jyh-Chemg Yu De-Chuan Chan Teng-Wei Chen Peng-Jen Chen Yao-Chi Liu Division of General Surgery Department ofSurgery Tri-Service General Hospital National Defense Medical Center Taipei Taiwan China Department of Radiology Tri-Service GeneralHospital National Defense Medical Center Taipei Taiwan China Division of Gastroenterology Department ofInternal Medicine Tri-Service General Hospital National Defense Medical Center Taipei Taiwan China Department of Surgery Yee-Zen General HospitalTauyan Taiwan China

A diagnosis of intestinal diverticulosis is difficult to make pre-operatively because the clinical symptoms are usually non-specific. We report the case of a 70-year-old man who had suffered from three episodes of intestinal obstruction in 1 year. He experienced dull pain and a sensation of fullness over the whole abdomen. The symptoms did not improve after conservative *** presumptive diagnosis was intestinal obstruction, and an exploratory laparotomy found diverticulosis of the proximal jejunum, with an adhesion band formed from the base of one diverticulum. Strangulation of a segment of the jejunum resulted from the internal herniation caused by the band. The band was removed and the proximal jejunum segmentally resected. His postoperative course was uneventful.

关键词： Diverticulosis of jejunum Intestinal obstruction

Y–Z deformable magnetic ring for the treatment of rectal stricture: A case report and review of literature

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World Journal of Gastroenterology 2024年第6期30卷 599-606页

作者： Miao-Miao Zhang huan-Chen Sha Yuan-fa Qin Yi Lyu Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina

BACKGROUND Treatment of postoperative anastomotic stenosis for colorectal cancer is often challenging,especially for patients who do not respond well to *** cases where patients have undergone an enterostomy,the stenosis can be easily resolved through magnetic ***,common magnetic compre-ssion techniques cannot be performed on those without *** design-ed a novel Y–Z deformable magnetic ring(Y–Z DMR)and successfully applied it to a patient with a stenosis rectal anastomosis and without enterostomy after rectal cancer *** SUMMARY We here report the case of a 57-year-old woman who had undergone a laparo-scopic radical rectum resection(Dixon)for rectal ***,she started facing difficulty in defecation 6 months after *** colonoscopy indicated stenosis of the rectal *** balloon dilation was performed six times on ***,the stenosis still showed a trend of gradual *** the patient did not undergo an enterostomy,the conventional endoscopic magnetic compression technique could not be ***,we imple-mented a Y–Z DMR implemented through the anus under single *** magnetic ring fell off nine days after the operation and the rectal stenosis was *** patient was followed up for six months and reported good *** The Y–Z DMR deformable magnetic ring is an excellent treatment strategy for patients with rectal stenosis and without enterostomy.

关键词： Anastomotic stenosis Colorectal cancer Magnetosurgery Magnetic compression technique Magnetic surgery clinic Case report

Drug delivery with Mn-doped MoO_(2) for photothermalenhanced chemotherapy in fighting cancers

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Rare Metals 2024年第5期43卷 2230-2240页

作者： Ping Zhao Hai-fa Zheng Ju Peng Xing-Long Li fazal Raziq Xiao-Jun Liu Hao-Quan Yu Jin-Lu Tang Yi-fan Kang Wen-huan huang School of Chemistry and Chemical Engineering Guangdong Pharmaceutical UniversityGuangzhou 510006China KAUST Catalysis Center King Abdullah University of Science and Technology23955-6900 ThuwalKingdom of Saudi Arabia Key Laboratory of Chemical Additives for China National Light Industry College of Chemistry and Chemical EngineeringShaanxi University of Science and TechnologyXi'an 710021China

Although chemotherapy has been intensively applied in cancer treatments,its inadequate therapeutic efficacy and severe side effects are still under constant *** used as anti-tumor drug delivery system(DDS)have attracted tremendous attentions owing to their various intriguing ***,Mn-doped MoO_(2)nanoparticles coated with ZrO_(2)and capped with Bi_(2)O_(3)have been designed as a DDS,namely *** possesses good magnetic properties,great photothermal conversion ability,sensitive tumor microenvironment(TME)responsiveness,and good biocompatibility in hemocompatibility in ***,MMZB has been utilized to load the chemotherapeutic agent daunomycin(DNM)(MMZB@DNM)for chemo-photothermal combined ***@DNM demonstrates a more impressive anti-cancer effect than the individual photothermal or chemotherapy both in vitro and in ***,the analysis of tumor specimen sections and serum levels after the treatment indicates negligible side effects for MMZB@DNM in *** contribution provides a valuable concept in designing therapeutic agents for achieving significantly enhanced tumor treatments,which benefits from the synergistic combination of chemotherapy and photothermal therapy in one single nanoagent.

关键词： Mn-doped MoO_(2) Bi_(2)O_(3) Nanocarrier Photothermal Chemotherapy

Treatment of anastomotic stricture after rectal cancer operation by magnetic compression technique:A case report

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1443-1448页

作者： Miao-Miao Zhang huan-Chen Sha Hai-Rong Xue Yuan-fa Qin fang-fang Dong Li Zhang Yi Lyu Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Shaanxi Provincial Key Laboratory of Magnetic Medicine The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Department of Gastroenterology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina

BACKGROUNDThe treatment of postoperative anastomotic stenosis(AS)after resection of colorectalcancer is *** balloon dilation is used to treat stenosisin such cases,but some patients do not show improvement even after multipleballoon *** compression technique(MCT)has been used for gastrointestinalanastomosis,but its use for the treatment of postoperative AS aftercolorectal cancer surgery has rarely been *** SUMMARYWe report a 72-year-old man who underwent radical resection of colorectal cancerand ileostomy one year *** ileostomy closure was prepared six months ago,but colonoscopy revealed a narrowing of the rectal *** balloondilation was performed three times,but colonoscopy showed no significantimprovement in *** AS was successfully treated using *** is a minimally invasive method that can be used for the treatment of postoperativeAS after colorectal cancer surgery.

关键词： Rectostenosis Magnetic surgery Magnetic Surgery Clinic Rectal cancer Magnetic compression technique Case report

Novel magnetic compression technique for the treatment of postoperative anastomotic stenosis in rectal cancer:A case report

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1926-1932页

作者： Miao-Miao Zhang huan-Chen Sha Hai-Rong Xue Yuan-fa Qin Xiao-Gang Song Yun Li Yu Li Zheng-Wu Deng Yu-Lin Gao fang-fang Dong Yi Lyu Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Department of Shaanxi Provincial Key Laboratory of Magnetic Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina

BACKGROUND The treatment of postoperative anastomotic stenosis after excision of rectal cancer is *** balloon dilation and radial incision are not effective in all *** present a new endoscopy-assisted magnetic compression technique(MCT)for the treatment of rectal anastomotic *** successfully applied this MCT to a patient who developed an anastomotic stricture after radical resection of rectal cancer.A 50-year-old man had undergone laparoscopic radical rectal cancer surgery at a local hospital 5 months ago.A colonoscopy performed 2 months ago indicated that the rectal anastomosis was narrow due to which ileostomy closure could not be *** patient came to the Magnetic Surgery Clinic of the First Affiliated Hospital of Xi'an Jiaotong University after learning that we had successfully treated patients with colorectal stenosis using *** performed endoscopy-assisted magnetic compression surgery for rectal *** magnets were removed 16 d later.A follow-up colonoscopy performed after 4 months showed good anastomotic patency,following which,ileostomy closure surgery was *** MCT is a simple,non-invasive technique for the treatment of anastomotic stricture after radical resection of rectal *** technique can be widely used in clinical settings.

关键词： Rectal cancer Magnetic compression technique Magnetosurgery Anastomotic stricture Magnetic surgery clinic Case report

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附石生物营养质量对干旱胁迫的响应及机制

水生态学杂志 2024年第3期45卷 21-31页

作者：李唤唤谭香张全发西藏大学生态环境学院西藏拉萨850000 中国科学院武汉植物园水生植物与流域生态重点实验室湖北武汉430074 中国科学院&湖北省丹江口湿地生态系统野外科学观测研究站湖北武汉430074

探讨河流附石生物营养质量对干旱的响应及机制,为河流生物膜研究和对全球气候变暖大背景下的脆弱水域保护提供科学支持。基于脂肪酸和化学计量学2种食物营养质量指示方法,利用中宇宙控制实验模拟野外干旱情景,研究了干旱对附石生物营养... 详细信息

探讨河流附石生物营养质量对干旱的响应及机制,为河流生物膜研究和对全球气候变暖大背景下的脆弱水域保护提供科学支持。基于脂肪酸和化学计量学2种食物营养质量指示方法,利用中宇宙控制实验模拟野外干旱情景,研究了干旱对附石生物营养质量的影响,并从宏观的附石生物膜藻类群落结构和微观的宏基因组技术2个层面探索其影响机制。结果表明,干旱后多不饱和脂肪酸(polyunsaturated fatty acid,PUfa)中的二十二碳六烯酸(docosahexaenoic acid,DHA)和二十碳五烯酸(eicosapentaenoic acid,EPA)等含量减少;附石生物中磷(P)含量显著减少(P<0.05),C/P、N/P增加。硅藻是附石生物膜中的优势类群,优质脂肪酸的生产者,富含EPA、DHA,干旱后硅藻密度和丰度显著减少(P<0.05)。基于宏基因组分析结果,附石生物脂质代谢通路中脂肪酸生物合成显著减少(P<0.05),脂肪酸降解显著增加(P<0.05),进而影响EPA、DHA的含量。干旱导致河流生态系统基础资源营养质量下降,进而可能对整个河流生态系统中消费者的生长和繁殖产生影响。研究结果从基础资源碳质量新视角为水生态系统食物网的碳源及传递研究提供了重要依据。

关键词：干旱胁迫附石生物脂肪酸营养质量宏基因组

Magnetic and electrical transport properties in GdAlSi and SmAlGe

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Chinese Physics B 2024年第7期33卷 554-560页

作者：巩静王欢马小平曾祥雨林浚发韩坤王乙婷夏天龙 Department of Physics Renmin University of ChinaBeijing 100872China Beijing Key Laboratory of Opto-electronic Functional Materials&Micro-nano Devices Renmin University of ChinaBeijing 100872China Key Laboratory of Quantum State Construction and Manipulation(Ministry of Education) Renmin University of ChinaBeijing 100872China Laboratory for Neutron Scattering Renmin University of ChinaBeijing 100872China

We conduct a detailed examination of the magnetic and electrical transport properties in GdAlSi and SmAlGe crystals,which possess a LaPtSi-type structure(space group I4_(1)md).The magnetic susceptibility data unambiguously reveal magnetic ordering below a characteristic transition temperature(T_(N)).For GdAlSi,a hysteresis loop is observed in the magnetization and magnetoresistance curves within the ab plane when the magnetic field is applied below T_(N),which is around32 *** specific heat anomalies are detected at 32 K for GdAlSi and 6 K for SmAlGe,confirming the occurrence of magnetic *** addition,the extracted magnetic entropy at high temperatures is consistent with the theoretical value of Rln(2J+1) for J=7/2 in Gd^(3+) and J=5/2 in Sm^(3+),*** also exhibits Schottky-like specific heat ***,both GdAlSi and SmAlGe exhibit positive magnetoresistance and a normal Hall effect.

关键词： crystal growth magnetism magnetotransport properties specific heat

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基于句法依赖增强图的方面级情感分析

计算机工程与设计 2024年第6期45卷 1857-1864页

作者：廖列法夏卫欢杨翌虢江西理工大学信息工程学院江西赣州341000 江西现代职业技术学院院长办公室江西南昌330095 上海大学计算机工程与科学学院上海200444

方面级情感分析旨在分析句子中特定方面的情感极性,现有研究侧重于利用图神经网络建模上下文与方面的依赖信息,忽略了对上下文中情感词及其词性的挖掘和利用。为此,提出一种基于句法依赖的增强图(syntactic dependency enhancement grap... 详细信息

方面级情感分析旨在分析句子中特定方面的情感极性,现有研究侧重于利用图神经网络建模上下文与方面的依赖信息,忽略了对上下文中情感词及其词性的挖掘和利用。为此,提出一种基于句法依赖的增强图(syntactic dependency enhancement graph, SDEG)模型,在原始句法依赖图上引入情感知识和词性信息,增强情感词权重和相关词性单词在上下文中的作用。使用双向长短期记忆网络和卷积神经网络捕捉句子的重点语义信息,通过图卷积神经网络建模句法依赖增强图,通过交互注意力机制生成特定方面的上下文语义和语法表示以进行情感极性分类。在多个公共基准数据集上的实验结果表明,所提模型在性能上有明显提升。

关键词：方面级情感分析情感知识词性双向长短期记忆网络卷积神经网络图卷积神经网络交互注意力机制