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Relationship between self-reported residential indoor remodeling and semen quality： a case-control study

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Asian Journal of Andrology 2015年第6期17卷 981-984,I0009,I0010页

作者： Mao-Hua Miao zheng Li De-Kun Li bei Yan Hong Liang Er-Lei Zhi Hong-Wei Du Wei Yuan Department of Reproductive Epidemiology and Social Science National Population and Family Planning Key Laboratory of Contraceptive Drugs and Devices ShanghaiI~stitue of Planned Pa[enthood Rese.arch Shanghai China Department of Urology Shanghai Human Sperm Bank Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China Division of Reseaich Kaiser Foundation Research Institute Kaiser Permanente Northern California CA USA.

The present study examined the association between residential indoor remodeling and poor semen quality. Sperm donors aged 18-45 years old were recruited in Shanghai, China. Semen specimens were collected and analyzed. An in-person interview was conducted to obtain information on the history of indoor remodeling and potential confounders. A total of 70 participants with abnormal semen quality （case group） and 68 controls were examined. A total of 20 subjects reported indoor remodeling in the recent 24 months, and among them 17 subjects reported indoor remodeling in the recent 12 months. Compared with participants with no history of indoor remodeling, participants with a history of indoor remodeling in the recent 24 months were more than three times as likely to have poor sperm quality （adjusted odds ratio = 3.8, 95% confidence interval： 1.3-12.0） after controlling for potential confounders. The association was strengthened when the analysis was restricted to those who had indoor remodeling in the recent 12 months. Our findings provide preliminary evidence that indoor remodeling has an adverse effect on semen quality.

关键词： case-control study chemicals health effect indoor remodeling semen quality

Developments in the study of Chinese herbal medicine's assessment index and action mechanism for diabetes mellitus

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Animal Models and Experimental Medicine 2024年第4期7卷 433-443页

作者： Xin-Yue Liu Han-Wen zheng Feng-Zhong Wang Tul-Wahab Atia bei Fan Qiong Wang Institute of Food Science and Technology Chinese Academy of Agricultural SciencesBeijingChina Sino-Portugal TCM International Cooperation Center the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical UniversityLuzhouChina Dr.Panjwani Center for Molecular Medicine and Drug Research International Center for Chemical and Biological SciencesUniversity of KarachiKarachiPakistan

In traditional Chinese medicine(TCM),based on various pathogenic symptoms and the‘golden chamber’medical text,Huangdi Neijing,diabetes mellitus falls under the category‘collateral disease’.TCM,with its wealth of experience,has been treating diabetes for over two *** antidiabetic Chinese herbal medicines re-duce blood sugar,with their effective ingredients exerting unique *** well as a glucose lowering effect,TCM also regulates bodily functions to prevent diabetes associated complications,with reduced side effects compared to western synthetic *** herbal medicine is usually composed of polysaccharides,saponins,al-kaloids,flavonoids,and *** active ingredients reduce blood sugar via various mechanism of actions that include boosting endogenous insulin secretion,enhancing insulin sensitivity and adjusting key enzyme activity and scavenging free *** actions regulate glycolipid metabolism in the body,eventually achiev-ing the goal of normalizing blood *** different animal models,a number of molecular markers are available for the detection of diabetes induction and the molecular pathology of the disease is becoming ***,there is a dearth of scientific data about the pharmacology,dose-effect relationship,and structure-activity relationship of TCM and its *** research into the efficacy,toxicity and mode of action of TCM,using different metabolic and molecular markers,is key to developing novel TCM antidiabetic formulations.

关键词： animal model Chinese herbal medicine diabetes mellitus evaluation index mechanism of action

黄酮配合物抗自由基活性的亚甲基蓝光谱测定体系的研究

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光谱学与光谱分析 2006年第12期26卷 2294-2297页

作者：李方郑怀礼四川大学化学学院四川成都610064 重庆大学化学化工学院重庆400044

亚甲基蓝(MB)可捕获Fenton反应产生的羟自由基生成无色加合物,选用亚甲基蓝为槲皮素(Que)及其配合物抗羟自由基活性测定体系的指示剂。实验优化测试条件为:体系pH 8.0,加入H2O2溶液(0.3%)0.50 mL,FeSO4溶液(5 mmol.L-1)0.50 mL和MB溶液(... 详细信息

亚甲基蓝(MB)可捕获Fenton反应产生的羟自由基生成无色加合物,选用亚甲基蓝为槲皮素(Que)及其配合物抗羟自由基活性测定体系的指示剂。实验优化测试条件为:体系pH 8.0,加入H2O2溶液(0.3%)0.50 mL,FeSO4溶液(5 mmol.L-1)0.50 mL和MB溶液(2.56×10-5mol.L-1)1.0 mL。由此建立了测定槲皮素配合物抗.OH活性的光谱测定方法。方法简便,尤其适合于配合物体系抗自由基活性的分析。测定了槲皮素及Que-Zn(Ⅱ),Que-Cu(Ⅱ),Que-Fe(Ⅲ)配合物的抗.OH活性。结果表明3种槲皮素配合物的抗羟自由基活性均比槲皮素高,配合物活性Que-Cu(Ⅱ)>Que-Zn(Ⅱ)>Que-Fe(Ⅲ),表现出金属离子与有机活性配体协同作用可提高其抗氧化活性的能力。

关键词：亚甲基蓝光谱法槲皮素配合物羟自由基

Quantum state and process tomography via adaptive measurements

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Science China(Physics,Mechanics & Astronomy) 2016年第10期59卷 25-32页

作者： HengYan Wang WenQiang zheng NengKun Yu KeRen Li DaWei Lu Tao Xin Carson Li zhengFeng Ji David Kribs bei Zeng XinHua Peng JiangFeng Du Hefei National Laboratory for Physical Sciences at Microscale and Department of Modern Physics University of Science and Technology of ChinaHefei 230026China Department of Applied Physics Zhejiang University of TechnologyHangzhou 310023China Institute for Quantum Computing University of WaterlooWaterloo N2L 3G1Canada 4Department of Mathematics&Statistics University of GuelphGuelph N1G 2W1Canada Centre for Quantum Computation&Intelligent Systems Faculty of Engineering and Information TechnologyUniversity of Technology SydneySydney NSW 2007Australia State Key Laboratory of Low-Dimensional Quantum Physics and Department of Physics Tsinghua UniversityBeijing 100084China Department of Physics University of GuelphGuelph N1G 2W1Canada State Key Laboratory of Computer Science Institute of SoftwareChinese Academy of SciencesBeijing 100190China Canadian Institute for Advanced Research Toronto M5G 1Z8Canada

We investigate quantum state tomography(QST) for pure states and quantum process tomography(QPT) for unitary channels via adaptive measurements. For a quantum system with a d-dimensional Hilbert space, we first propose an adaptive protocol where only 2d. 1 measurement outcomes are used to accomplish the QST for all pure states. This idea is then extended to study QPT for unitary channels, where an adaptive unitary process tomography(AUPT) protocol of d2+d.1measurement outcomes is constructed for any unitary channel. We experimentally implement the AUPT protocol in a 2-qubit nuclear magnetic resonance system. We examine the performance of the AUPT protocol when applied to Hadamard gate, T gate(/8 phase gate), and controlled-NOT gate,respectively, as these gates form the universal gate set for quantum information processing purpose. As a comparison, standard QPT is also implemented for each gate. Our experimental results show that the AUPT protocol that reconstructing unitary channels via adaptive measurements significantly reduce the number of experiments required by standard QPT without considerable loss of fidelity.

关键词： quantum tomography state reconstruction nuclear magnetic resonance

Single-center Experience in the Diagnosis and Treatment of Hepatic Perivascular Epithelioid Cell Neoplasm

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Journal of Clinical and Translational Hepatology 2022年第1期10卷 72-79页

作者： Junjun Jia Jia Luo Cheng-Gen Pan Guomei Ge Meibao Feng bei Zou Li Liu Shusen zheng Jun Yu Division of Hepatobiliary and Pancreatic Surgery Department of SurgeryThe First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiangChina Key Laboratory of Organ Transplantation Research Center for Diagnosis and Treatment of Hepatobiliary DiseasesHangzhouZhejiangChina Department of Pathology The First Affiliated Hospi-talCollege of MedicineHangzhouZhejiangChina Department of Library The First Affiliated HospitalZhejiang Univer-sity School of MedicineHangzhouZhejiangChina

Background and Aims:Perivascular epithelioid cell neo-plasms(PEComas)are a rare type of mesenchymal neo-plasm and their preoperative diagnosis is *** this study,we summarized the experience from a single medical center to study the examinations,clinical presen-tations,and pathological and histological characteristics of PEComas in the liver in order to optimize overall un-derstanding of the diagnosis and treatment of these ***:We conducted a retrospective analysis to investigate the clinical and pathological characteristics as well as imaging presentations of 75 patients diagnosed with hepatic PEComa in The First Affiliated Hospital of Zhe-jiang University between April 2010 and April ***-sults:Among the 75 patients,52 were women,and the median age was 48 *** patients had no specific symptoms,and two were admitted to the hospital for a second time owing to *** patients underwent surgi-cal ***,38 patients had classical angio-myolipoma(AML)and 37 had epithelioid *** PECo-mas were accompanied by positive immunohistochemical expression of HMB45,Melan-A,and smooth muscle ***-up data were obtained from 47 of the total 75 pa-tients,through October *** patients had metastasis after ***:AML is the most common type of hepatic *** are no specific symptoms of he-patic PEComa,and serological examinations and imaging modalities for accurate preoperative diagnosis are *** AML should be considered a tumor of uncertain malignant potential;however,the prognosis of PEComa af-ter resection is promising.

关键词： Liver Perivascular epithelioid cell neoplasms Diagnosis Treatment

C–C motif chemokine ligand 16 inhibits the progression of liver cirrhosis via inactivating hepatic stellate cells

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Hepatobiliary & Pancreatic Diseases International 2020年第5期19卷 440-448页

作者： Jian-Yong Zhuo Di Lu Zu-Yuan Lin bei-Ni Cen Xu-Yong Wei Hai-Yang Xie Shu-Sen zheng Xiao Xu Department of Hepatobiliary and Pancreatic Surgery the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China NHC Key Laboratory of Combined Multi-organ Transplantation Key Laboratory of the Diagnosis and Treatment of Organ TransplantationCAMSHangzhou 310003China Department of Hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalHangzhou 310003China

Background:Liver cirrhosis results from many forms of chronic damage,characterized by accumulation of extracellular *** present study aimed to explore a potential non-invasive biomarker and its mechanism in the progression of liver ***:Gene Expression Omnibus(GEO)dataset(GSE15654,n=216)was analyzed to screen genes associated with progression of liver cirrhosis.A total of 181 plasma samples,including healthy control(HC,n=20),chronic hepatitis B(CHB,n=77)and HBV-related liver cirrhosis(LC,n=84),were enrolled for *** vitro and in vivo experiments were employed for the mechanistic ***:GEO dataset analysis showed that relatively low mRNA-expression of C–C motif chemokine ligand 16(CCL16)was associated with elevated Child-Pugh score(P=0.034)and worse prognosis(P=0.025).Plasma CCL16 level decreased in a stepwise pattern,with a median concentration of 10.29,6.57 and 4.47 ng/mL in the HC,CHB and LC groups,respectively(P<0.001).Low plasma CCL16 was significantly related to hepatic dysfunction both in the CHB and LC groups(P<0.05).Combination of CCL16 and ALT showed improved distinguishing capability for LC compared to either *** vitro,CCL16 expression was downregulated by lipopolysaccharide and *** of CCL16 from human normal liver cell line(LO2)reduced the extracellular matrix associated proteins(Col1 and Col4)in human hepatic stellate cell line(LX-2).In vivo,the pathological feature of cirrhosis was alleviated by the hepatocytespecific expression of ***:CCL16 could be a feasible plasma marker to predict the occurrence and progression of liver ***16 might impact liver cirrhosis through inactivating hepatic stellate cells.

关键词： C-C motif chemokine ligand 16 Liver cirrhosis Hepatitis B virus infection

Broad Cell Tropism of SADS-CoV In Vitro Implies Its Potential Cross-Species Infection Risk

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Virologica Sinica 2021年第3期36卷 559-563页

作者： Yun Luo Ying Chen Rong Geng bei Li Jing Chen Kai Zhao Xiao-Shuang zheng Wei Zhang Peng Zhou Xing-Lou Yang zheng-Li Shi CAS Key Laboratory of Special Pathogens and Biosafety Wuhan Institute of VirologyCenter for Biosafety Mega-ScienceChinese Academy of SciencesWuhan 430071China University of Chinese Academy of Sciences Beijing 100049China

Dear Editor,Swine acute diarrhoea syndrome coronavirus (SADS-Co V)is a novel swine enteric coronavirus belonged to the Coronaviridae family,Alphacoronavirus genus (Zhou P et al.2018).The clinical signs of SADS include acute diarrhoea and vomiting,which was similar with the infection of porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCo V)(Wang et al.2019).

关键词： Swine swine PEDV

Accurate correction of arbitrary spin fermion quantum tunneling from non-stationary Kerr-de Sitter black hole based on corrected Lorentz dispersion relation

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Chinese Physics C 2020年第12期44卷 226-233页

作者： bei Sha Zhi-E Liu Yu-Zhen Liu Xia Tan Jie Zhang Shu-zheng Yang School of Physics and Electronic Engineering Qilu Normal UniversityJinan 250200China College of Physics and Space Science China West Normal UniversityNanchong 637002China

According to a corrected dispersion relation proposed in the study on the string theory and quantum gravity theory,the Rarita-Schwinger equation was precisely modified,which resulted in the Rarita-Schwinger-Hamilton-Jacobi *** this equation,the characteristics of arbitrary spin fermion quantum tunneling radiation from non-stationary Kerr-de Sitter black holes were determined.A number of accurately corrected physical quantities,such as surface gravity,chemical potential,tunneling probability,and Hawking temperature,which describe the properties of black holes,were *** research has enriched the research methods and enabled increased precision in black hole physics research.

关键词： black hole rermions tunneling radiation Lorentz dispersion relation

MATHEMATICAL MODEL FOR THE FLOW WITH SUBMERGED AND EMERGED RIGID VEGETATION

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Journal of Hydrodynamics 2009年第5期21卷 722-729页

作者： huai Wen-xin CHEN zheng-bing HAN Jie ZHANG Li-xiang ZENG Yu-hong State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan University Wuhan430072 China Department of Engineering Mechanics Kunming University of Science and Technology Kunming 650051 China

The article summarizes previous studies on the flow in open channels with rigid vegetation, and constructs a mathematical model for submerged and emerged rigid vegetation. The model involves the forces balance in the control volume in one-dimensional steady uniform flow. For submerged vegetation, the whole flow is divided into four regions： external region, upper vegetated region, transition region and viscous region. According to the Karrnan similarity theory, the article improves the mixing length expression, and then gives an analytical solution to predict the vertical distribution of stream-wise velocity in the external region. For emerged vegetation, the flow is divided into two region： outer region and viscous region. In the two circumstances, the thicknesses of each region are determined respectively. The comparison between the calculated results and our experimental data and other researchers＇ data proves that the proposed model is effective.

关键词： Karman similarity theory mixing length submerged and emerged rigid vegetation velocity distribution