检索结果-南通市图书馆

Influence of Hypertension, Lipometabolism Disorders,Obesity and Other Lifestyles on SpontaneousIntracerebral Hemorrhage

引用

Biomedical and Environmental Sciences 2003年第3期16卷 295-303页

作者： JUN-FUZHOU JI-YUEWANG YAN-ERLUO huai-hongchen SecondAffiliatedHospitalofCollegeofMedicine ZhejiangUniversity88JiefangRoadHangzhou310009ZhejiangChina AffiliatedChildren‘sHospital MedicalCollegeZhejiangUniversity57ZhuganLaneHangzhou310003ZhejiangChina FuyangMunicipalHospitalofTraditionalChineseMedicine 4BeimenRoadFuyang311400ZhejiangChina BrainMedicineResearchInstituteofZhejiangUniversity 88JiefangRoadHangzhou310009ZhejiangChina

Objective To investigate whether hypertension, abnormal lipometabolism, obesity, cigarette smoking and alcohol drinking affect the intracerebral hemorrhagic volumes (IHV) in patients with spontaneous intracerebral hemorrhage (SIHP), and to explore the roles of these factors in spontaneous intracerebral hemorrhage (SIH). Methods Five hundred patients with acute SIH and 200 healthy adult volunteers (HAV) were enrolled in a study of independently randomized controlled design, in which the levels of systolic pressure (SP) and diastolic pressure (DP), and total cholesterol (TCH), triacylglycerols (triglycerides, TG), high density lipoprotein cholesterol (HDL-CH), low density lipoprotein cholesterol (LDL-CH) in serum as well as the level of erythrocytic membrane cholesterol (EM-CH) were measured, and the body mass index (BMI), daily cigarette smoking consumption (DCSC) and daily pure alcohol consumption (DPAC) were calculated. Results Compared with the average parameters in the HAV group, those of SP, DP, TG, LDL-CH and BMI in the SIHP group were significantly increased (P<0.0001), while those of HDL-CH and EM-CH were significantly decreased (P<0.0001). The linear regression and correlation analysis showed that with increased SP, DP, LDL-CH, BMI, DCSC, DPAC and aging as well as decreased HDL-CH and EM-CH, the IHV levels in SIHP were increased gradually (P<0.0001-0.01). The linear stepwise regression analysis suggested that there existed a close correlation among the values of SP, DP, TCH, TG, HDL-CH, LDL-CH, EM-CH, BMI, DCSC, DPAC, age and fflV of the SIH patients, and that Y = - 12.4583 + 0.1127SP -1.1977EM-CH + 0.9788LDL-CH + 0.2477BMI + 0.0382DCSC + 0.0248DP,P<0.0001-0.05. Conclusions The findings in the present study suggest that significantly increased systolic and diastolic pressure, low density lipoprotein cholesterol, body mass index and daily cigarette smoking consumption, and significantly decreased erythrocytic membrane cholesterol may be likely the main factor

关键词： Blood pressure Lipids Cigarette smoking Alcohol drinking Body mass index Spontaneous intracerebral hemorrhage Intracerebral hemorrhagic volume

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

3,4-Methylenedioxymethamphetamine(MDMA)Abuse Markedly Inhibits Acetylcholinesterase Activity and Induces Severe Oxidative Damage and Liperoxidative Damage

引用

Biomedical and Environmental Sciences 2003年第1期16卷 53-61页

作者： JUN-FUZHOU YE-ZHOU LINAGZHANG huai-hongchen DONGCAI SecondAffiliatedHospital CollegeofMedicineZhejiangUniversity88JiefangRoadHangzhou310009ZhejiangProvinceChina HangzhouMunicipalPublicSecurityBureau 35HuaguangRoadHangzhou310002ZhejiangProvinceChina. ZhejiangSurveillanceStationofDrugAbuse 88JiefangRoadHangzhou310009ZhejiangprovinceChina

Objective To investigate whether 3,4-methylenedioxymethamphetamine (MDMA) abuse produces another neurotoxicity which may significantly inhibit the acetylcholinesterase activity and result in severe oxidative damage and liperoxidative damage to MDMA abusers. Methods 120 MDMA abusers (MA) and 120 healthy volunteers (HV) were enrolled in an independent sample control design, in which the levels of lipoperoxide (LPO) in plasma and erythrocytes as well as the activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and acetylcholinesterase (AChE) in erythrocytes were determined by spectrophotometric methods. Results Compared with the average values of biochemical parameters in the HV group, those of LPO in plasma and erythrocytes in the MA group were significantly increased (P<0.0001), while those of SOD, CAT, GPX and AChE in erythrocytes in the MA group were significantly decreased (P<0.0001). The Pearson product-moment correlation analysis between the values of AChE and biochemical parameters in 120 MDMA abusers showed that significant linear negative correlation was present between the activity of AChE and the levels of LPO in plasma and erythrocytes (P<0.0005-0.0001), while significant linear positive correlation was observed between the activity of AchE and the activities of SOD, CAT and GPX (P<0.0001). The reliability analysis for the above biochemical parameters reflecting oxidative and lipoperoxidative damages in MDMA abusers suggested that the reliability coefficient (alpha) was 0.8124, and that the standardized item alpha was 0.9453. Conclusion The findings in the present study suggest that MDMA abuse can induce another neurotoxicity that significantly inhibits acetylcholinesterase activity and aggravates a series of free radical chain reactions and oxidative stress in the bodies of MDMA abusers, thereby resulting in severe neural, oxidative and lipoperoxidative damages in MDMA abusers.

关键词： 3,4-Methylenedioxymethamphetamine MDMA Drug abuse Acetylcholinesterase Free radicals Lipoperoxide Antioxidase Oxidative stress Oxidative damage Lipoperoxidative damage

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Oxidative Stress and Free Radical Damage in Patients With Acute Dipterex Poisoning

引用

Biomedical and Environmental Sciences 2004年第2期17卷 223-233页

作者： JUN-FuZHOU WENZHOU SHU-MEIZHANG YAN-ERLUO huai-hongchen SecondAffiliatedHospitalofCollegeofMedicine ZhejiangUniversity88JiefangRoadHangzhou310009ZhejiangChina FuyangMunicipalHospitalofTraditionalChineseMedicine 4BeimenRoadFuyang311400ZhejiangChina ZhejiangSurveillanceStationofDrugAbuse 88JiefangRoadHangzhou310009ZhejiangChina

Objective To investigate whether acute dipterex poisoning (ADP) may cause oxidative stress and free radical damage in the bodies of acute dipterex poisoning patients (ADPPs), and to explore the mechanisms by which ADP may cause oxidative stress and free radical damage. Methods Fifty ADPPs and fifty healthy adult volunteers (HAVs) whose ages, gender and others were matched with the ADPPs were enrolled in a randomized controlled study, in which concentrations of nitric oxide (NO), vitamin C (VC), vitamin E (VE) and P-carotene (P-CAR) in plasma as well as concentration of lipoperoxide (LPO), and activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and acetylcholinesterase (AChE) in erythrocytes were determined by spectrophotometric analytical methods. Results Compared with the average values of experimental parameters in the HAVs group, the average values of plasma NO and erythrocyte LPO in the ADPPs group were significantly increased (P<0.0001), while those of plasma VC, VE and P-CAR as well as erythrocyte SOD, CAT, GPX and AChE in the ADPPs group were significantly decreased (P<0.0001). Bivariate correlation analysis and partial correlation analysis suggested that when NO and LPO values were increased, and VC, VE, β-CAR, SOD, CAT and GPX values were decreased in the ADPPs, AChE value was decreased gradually in the ADPPs (P<0.001-0.0001). Reliability analysis of experimental parameters reflecting oxidative stress and free radical damage in the ADPPs showed that the reliability coefficient (8 items) alpha=0.6909, and the standardized item alpha=0.8574. Conclusion The findings in the present study suggest that ADP can cause oxidative stress and free radical damage, and inhibit markedly erythrocyte acetylcholinesterase activity in ADPPs.

关键词： Dipterex Dipterex poisoning Oxidative stress Free radical damage Free radicals Oxidation Lipoperoxidation Acetylcholinesterase

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of Local-Lag Mechanism on Task Performance in a Desktop CVE System

引用

Journal of Computer Science & Technology 2005年第3期20卷 396-401页

作者： hongchen LingChen Gen-CaiChen CollegeofComputerScience ZhejiangUniversityHangzhou310027P.R.China

Consistency maintenance is a kernel problem in Collaborative VirtualEnvironment (CVE) research. The approaches used in Networked Virtual Environments (e.g., DRalgorithm) could not be used in CVEs, for they could not prevent short-term ***, local-lag mechanism has been proposed to eliminate short-term inconsistency in *** a proper lag value is a key problem in local-lag mechanism. This paper studied the effectsof lag value (0ms-900ms) on task performance in a desktop CVE system. Experimental results indicatethat the effect of lag value on task performance is not linear. The effect could be separated intofour segments by three dividing points: 150ms, 300ms and 600ms. Lag has no effect on taskperformance while ranging from 0ms to 150ms. From 150ms to 300ms, lag slightly affects taskperformance. Lag deteriorates task performance seriously while ranging from 300ms to 600ms. When lagis longer than 600ms, the task cannot be accomplished sometimes.

关键词： CVE consistency lag response time task performance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

An energy-consistent fracture model for ferroelectrics

引用

Acta Mechanica Sinica 2017年第1期33卷 106-119页

作者： hongchen Miao Faxin Li LTCS and Department of Mechanics and Engineering Science College of Engineering Peking UniversityBeijing 100871 China Center for Applied Physics and Techniques Peking University Beijing 100871 China

The fracture behavior of ferroelectrics has been intensively studied in recent decades, though currently a widely accepted fracture mechanism is still lacking. In this work, enlightened by previous experimental observations that crack propagation in ferroelectrics is always accompanied by domain switching, we propose a micromechanical model in which both crack propagation and domain switching are controlled by energy-based criteria. Both electric energy and mechanical energy can induce domain switching, while only mechanical energy can drive crack propagation. Furthermore, constrained domain switching is considered in this model, leading to the gradient domain switching zone near the crack tip. Analysis results show that stress-induced ferroelastic switching always has a toughening effect as the mechanical energy release rate serves as the driving force for both fracture and domain switching. In comparison, the electric-field-induced switching may have either a toughening or detoughening effect. The proposed model can qualitatively agree with the existing experimental results.

关键词： Fracture Ferroelectrics Domain switching Energy release rate

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A cellulose-based lithium-ion battery separator with regulated ionic transport and high thermal stability for extreme environments

引用

Nano Research 2025年第1期18卷 315-322页

作者： Kun-Peng Yang Song Xie Zi-Meng Han Hao-Cheng Liu Chong-Han Yin Wen-Bin Sun Zhang-Chi Ling huai-Bin Yang De-Han Li Qing-Fang Guan Shu-Hong Yu Department of Chemistry New Cornerstone Science LaboratoryInstitute of Biomimetic Materials&ChemistryAnhui Engineering Laboratory of Biomimetic MaterialsDivision of Nanomaterials&ChemistryHefei National Research Center for Physical Sciences at the MicroscaleUniversity of Science and Technology of ChinaHefei 230026China Institute of Innovative Materials Department of Materials Science and EngineeringDepartment of ChemistrySouthern University of Science and TechnologyShenzhen 518055China

Separators play a critical role in lithium-ion ***,the restrictions of thermal stability and inferior electrical performance in commercial polyolefin separators significantly limit their applications under harsh ***,we report a cellulose-assisted self-assembly strategy to construct a cellulose-based separator massively and *** an ultrahigh ionic conductivity in electrolytes of 3.7 mS·cm^(-1) and the ability to regulate ion transport,the obtained separator is a promising alternative for high-performance lithium-ion *** addition,integrated with high thermal stability,the cellulose-based separator endows batteries with high safety at high temperatures,greatly expanding the application scenarios of energy storage devices in extreme environments.

关键词： lithium-ion batteries bio-inspired materials battery separators cellulose nanofiber ultrahigh ionic conductivity high safety

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Preparation of Perovskite Nano Powder by Sol-gel from DTPA and the Mechanism of Thermal Decomposition

引用

Chinese Chemical Letters 2004年第6期15卷 721-724页

作者： ZunLiMO hongchen KunJieWANG ZhengHaiSHI HeJunLI CollegeofMaterialscienceandEngineering NorthwesternPolitechnicalUniversityXi＇an710072 CollegeofChemistryandChemicalEngineering NorthwestNormalUniversityLanzhou730070 CollegeofMaterialscienceandEngineering NorthwesternPolitechnicalUniversityXi＇an710072

Dy0.8Sr0.2FeO3 nano powder, a synthetic oxide, is made by sol-gel method from metal nitrate and diethylenetriaminepentaacetic acid (DTPA), and the processing parameters are optimized. The process of the preparation, thermal decomposition and the property of the powder are studied by TG-DTA, IR, TEM, and XRD. The diameter of the average grain is about 70 nm. This new technique can be used in the preparation and the studying of na'no materials in the complex oxide system.

关键词： Nano powder sol-gel perovskite diethylenetriaminepentaacetic acid.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Au-Fe_3O_4 heterostructures for catalytic, analytical, and biomedical applications

引用

Chinese Chemical Letters 2018年第12期29卷 1725-1730页

作者： Baoling Liu hongchen Zhang Ya Ding Key Laboratory of Drug Quality Control and Pharmacovigilance China Pharmaceutical University Beijing Key Laboratory of Magnetoelectric Materials and Devices (BKL-MEMD) Beijing Innovation Center for Engineering Science and Advanced Technology(BIC-ESAT)Department of Materials Science and EngineeringCollege of EngineeringPeking University

Heterostructures are a series of nanomaterials combining different components into a single nanostructure. Au-FeOheterostructures have received considerable attentions because of their superior properties coming from both individual and combinational features of gold and iron oxide nanoparticles. Their intrinsically peculiar magnetic, optical properties, and structure designability greatly enhance and broaden their potential applications in catalysis, assay, multimodal imaging, and synergistic treatment for tumor. In this review, we systematically introduce the preparation methods of Au-FeOheterostructures and their potential applications in the biomedical field, focusing on the unique synergistic effect caused by the combination of gold and iron oxide structures. This review will provide insights into the structure control in adjusting the function of heterogeneous or hybrid material, such as Au-FeOheterostructures, to implement their biomedical applications.

关键词： Au-Fe_3O_4 heterostructures Janus nanoparticles Catalyst Multimodal imaging Synergistic treatment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An Empiric Linear Formula between the Internal Tetrahedron Symmetric Stretch Frequency and the Al Content in the Framework of KL Molecular Sieves

引用

Chinese Chemical Letters 2003年第8期14卷 870-873页

作者： JianXinTANG PengFengXIAO hongchen NongYueHE ChunYANG KeyLabofNewMaterialsandTechnologyofChinaNationalPackagingCorporation ZhnzhnuEngineeringCollegeZhnzhnu412008 KeyLaboratoryforMolecularandBiomoleeularElectronicsofMinistryofEducation SoutheastUniversityNanjing2 KeyLabofNewMaterialsandTechnologyofChinaNationalPackagingCorporation ZhnzhnuEngineeringCollegeZhnzhnu412008 KeyLaboratoryforMolecularandBiomoleeularElectronicsofMinistryofEducation SoutheastUniversityNanjing2 DepartmentofChemistry NanjingNormalUniversityNanjing210097

KL molecular sieves with different framework compositions were secondarily synthesized by substituting Si for Al with a solution of (NH 4)2SiF6. The internal tetrahedron symmetric stretch frequency, at ∼770 cm-1, is linear with the molar fraction of Al (XAl= Al/(Si+Al)) in the framework of KL samples: XAl = -7.309 × 10-3 (ν770-760) + 0.3242.

关键词： KL molecular sieve infrared spectroscopy linearity framework composition.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Biogeochemistry and geomicrobiology in extreme environments:Preface

引用

Geoscience Frontiers 2012年第3期3卷 269-271页

作者： hongchen Jiang hongchen.jiang@*** (Guest Editor) State Key Laboratory of Biogeology and Environmental Geology China University of Geosciences Wuhan 430074 China

1. IntroductionGeomicrobiology as an interdisciplinary area has achieved great progress during the past two decades （Dong and Yu, 2007）. Geomicrobiology involves the study of microbes in a number of fundamental geological processes, both in the past and present （Gadd, 2010）. Biogeochemistry in extreme geological environments is one of the key topics under this theme. The extreme environments include alkaline, acidic,

关键词： Zhang Li Biogeochemistry and geomicrobiology in extreme environments

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：