检索结果-南通市图书馆

Microstructure and Mechanical Properties in Friction Stir Welded Thick Al–Zn–Mg–Cu Alloy Plate

Acta Metallurgica Sinica(English Letters) 2022年第8期35卷 1329-1342页

作者： Fei Qiang Wen Wang Ke Qiao Pai Peng Ting Zhang xiao-Hu Guan Jun Cai Qiang Meng hua-xia zhao Kuai-She Wang School of Metallurgical Engineering National and Local Joint Engineering Research Center for Functional Materials ProcessingXi'an University of Architecture and TechnologyXi'an 710055China Northwest Institute for Non-Ferrous Metal Research Xian 710016China AVIC Manufacturing Technology Institute Bejing 100024China Beijing FSW Technology Co.Ltd Bejing 101107China

In this work, 20-mm-thick aluminum-alloy plates were joined via friction stir welding. The temperature gradient was reduced by reducing the surface welding heat input to achieve uniformity of the mechanical properties across the thick plate joints. The welding temperature was measured using thermocouples. The microstructures were observed via electron backscatter diff raction and transmission electron microscopy. The tensile properties of the samples sliced along the thickness direction of the joint were evaluated. The results show that the highest welding peak temperature is 430℃ on the advancing side on the top surface of the joint. The grain size gradually decreased along the thickness direction, and grain refi nement was due to the combination of continuous, discontinuous, and geometric dynamic recrystallization. The tensile properties of the sliced samples were found to be uniform, and the ultimate tensile strength reached 62% of that of the base metal. The main strengthening mechanism of the Al–Zn–Mg–Cu alloy joints consists of precipitation strengthening. In addition, the η ` → η phase transition and grain coarsening in the heat-affected zone were found to be responsible for the fracture of the joints.

关键词： Friction stir welding Aluminum alloy thick plate Dynamic recrystallization Mechanical properties Precipitated phase

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Subretinal fibrosis secondary to neovascular age-related macular degeneration:mechanisms and potential therapeutic targets

引用

Neural Regeneration Research 2025年第2期20卷 378-393页

作者： Jingxiang Zhang xia Sheng Quanju Ding Yujun Wang Jiwei zhao Jingfa Zhang Department of Ophthalmology People’s Hospital of Huangdao DistrictQingdaoShandong ProvinceChina Department of Urology People’s Hospital of Huangdao DistrictQingdaoShandong ProvinceChina Department of Ophthalmology Shanghai General Hospital(Shanghai First People’s Hospital)Shanghai Jiao Tong University School of MedicineShanghaiChina National Clinical Research Center for Eye Diseases Shanghai Key Laboratory of Ocular Fundus DiseasesShanghai Engineering Center for Visual Science and PhotomedicineShanghai Engineering Center for Precise Diagnosis and Treatment of Eye DiseasesShanghaiChina

Subretinal fibrosis is the end-stage sequelae of neovascular age-related macular *** causes local damage to photoreceptors,retinal pigment epithelium,and choroidal vessels,which leads to permanent central vision loss of patients with neovascular age-related macular *** pathogenesis of subretinal fibrosis is complex,and the underlying mechanisms are largely ***,there are no effective treatment options.A thorough understanding of the pathogenesis of subretinal fibrosis and its related mechanisms is important to elucidate its complications and explore potential *** current article reviews several aspects of subretinal fibrosis,including the current understanding on the relationship between neovascular age-related macular degeneration and subretinal fibrosis;multimodal imaging techniques for subretinal fibrosis;animal models for studying subretinal fibrosis;cellular and non-cellular constituents of subretinal fibrosis;pathophysiological mechanisms involved in subretinal fibrosis,such as aging,infiltration of macrophages,different sources of mesenchymal transition to myofibroblast,and activation of complement system and immune cells;and several key molecules and signaling pathways participating in the pathogenesis of subretinal fibrosis,such as vascular endothelial growth factor,connective tissue growth factor,fibroblast growth factor 2,platelet-derived growth factor and platelet-derived growth factor receptor-β,transforming growth factor-βsignaling pathway,Wnt signaling pathway,and the axis of heat shock protein 70-Toll-like receptors 2/*** review will improve the understanding of the pathogenesis of subretinal fibrosis,allow the discovery of molecular targets,and explore potential treatments for the management of subretinal fibrosis.

关键词： choroidal neovascularization epithelial-mesenchymal transition mesenchymal transition myofibroblast neovascular age-related macular degeneration submacular fibrosis subretinal fibrosis therapeutic targets transforming growth factor-β vascular endothelial growth factor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

农村宅基地使用权流转价格评估研究

引用

土壤通报 2018年第5期49卷 1054-1059页

作者：赖夏华赵小敏郭熙周丙娟江西农业大学江西南昌330045

在农村宅基地改革背景下,评估宅基地使用权流转价格,可为农村宅基地合理有序流转提供价格依据,是我国城乡建设用地价格体系研究的重要内容之一。剩余法、路线价法和基准地价修正系数法,不适用于目前余江县农村宅基地流转价格;成本法和... 详细信息

在农村宅基地改革背景下,评估宅基地使用权流转价格,可为农村宅基地合理有序流转提供价格依据,是我国城乡建设用地价格体系研究的重要内容之一。剩余法、路线价法和基准地价修正系数法,不适用于目前余江县农村宅基地流转价格;成本法和市场比较法适用于农村宅基地价格评估,收益还原法可辅助成本法使用。运用成本法评估宅基地使用权流转价格在建筑成本、相关税费和投资利润等参数上有别于城镇住宅用地评估。成本法和市场比较法评估的宅基地使用权流转价格与实际交易价格误差在10%以内,估算的价格浮动于余江县村集体100元m^(-2)的择位竞价。成本法评估会造成宅基地使用权流转价格偏低,结合市场比较法最终确定宅基地使用权流转价格时,可根据地区市场发育程度适当调整市场法权重。

关键词：农村宅基地使用权流转价格评估成本法市场比较法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rapid and scalable preparation of highly quaternized polymer networks to achieve efficient simultaneous adsorption of iodide and pertechnetate

引用

Science China Chemistry 2025年第01期 337-349页

作者： Meiyun Xu Song Gu Fulong Chen Zhe zhao Peng Liu Daoben hua State Key Laboratory of Radiation Medicine and Protection School of Radiological and Interdisciplinary Sciences (RAD-X) Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions Soochow University

The efficient separation of fission products,such as TcO4-and I-,holds strategic significance for the management of radioactive wastes and environmental *** this study,we propose an ultrafast strategy for scalable preparation of a highly quaternized organic network to facilitate efficient and synchronous separation of iodide and *** network can be prepared within a few minutes at room temperature,using polyethylenimine and 1,2,4,5-tetrakis（bromomethyl）benzene as building *** chlorine replacement,the network,abundantly decorated with quaternary ammonium groups （Cl@QPN）,exhibits an ultrahigh positive charge density of 7.6 mmol/*** enables the rapid and efficient enrichment of target anions through strong electrostatic Coulomb *** a result,Cl@QPN exhibits significantly higher adsorption rate constants of 0.830 g/（mg min） for ReO4-（a nonradioactive surrogate of TcO4-） and 0.677 g/（mg min） for I-compared to other ***,it possesses high adsorption capacities,reaching 1,681 mg/g for ReO4-and 917.4 mg/g for I-.Cl@QPN also demonstrates good selectivity towards target ions and shows efficient adsorption for99TcO4-.Additionally,Cl@QPN exhibits high dynamic processing capacities,handling up to 3,100 and 7,400 kg of simulated streams per kilogram of material for I-and ReO4-,respectively.

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Purification and Characterization of Alginate Lyase from Marine Vibrio ***

引用

Acta Biochimica et Biophysica Sinica 2006年第9期38卷 633-638页

作者： Yuan-Hong WANG* Guang-Li YU Xin-Min WANG Zhi-hua LV xia zhao Zhi-Hong WU Wei-Shang JI Marine Drug and Food Institute,Key Laboratory of Marine Drugs of Shandong Province,Key Laboratory of Marine Drugs,Ministry of Education,Ocean University of China,Qingdao 266003,China Marine Drug and Food Institute Key Laboratory of Marine Drugs of Shandong Province Key Laboratory of Marine Drugs Ministry of Education Ocean University of China Qingdao 266003 China. yhwang@***

Extracellular alginate lyase secreted by marine Vibrio ***,isolated from decayedLaminaria japonica,was purified by a combination of ammonium sulfate precipitation and diethylaminoethyl-Sephacel column *** results show that the molecular mass of alginate lyase wasapproximately 62.5 kDa,with an optimal pH and temperature at pH 7.0 and 25℃,*** wasapproximately 72.73 g/*** activity of the enzyme was enhanced by EDTA and Zn2+,but inhibited by Ba2+.The substrates specificity analysis shows that it was specific for hydrolyzing poly-β-D-1,4-mannuronate inalginate.

关键词： marine Vibrio alginate alginate lyase purification characterization

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Analysis of 5-year survival rate and risk factors in systemic lupus erythematosus

Analysis of 5-year survival rate and risk factors in systemi...

引用

The 8th International Congress on SLE

作者： Li-min Ren hua Ye Jin-xia zhao Zhan-guo Li Department of Rheumatoiogy & Immunology The People’s Hospital Peking University Beijing China 100044

＜正＞Purpose:To analyze the 5 years survival rate,cause of death and risk factors of systemic lupus erythematosus（SLE）. Methods:A retrospective analysis was performed on 138 SLE patients attending our department fr...

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

The complex roles of m^(6)A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases

引用

Neural Regeneration Research 2025年第6期20卷 1582-1598页

作者： Yanxi Li Jing Xue Yuejia Ma Ke Ye Xue zhao Fangliang Ge Feifei Zheng Lulu Liu Xu Gao Dayong Wang Qing xia Department of Biochemistry and Molecular Biology College of Basic Medical SciencesHarbin Medical UniversityHarbinHeilongjiang ProvinceChina College of Basic Medical Sciences Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Basic Medical Institute Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Key Laboratory of Heilongjiang Province for Genetically Modified Animals Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Translational Medicine Research and Cooperation Center of Northern China Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijingChina

N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis and neural regeneration, where it is highly concentrated and actively involved in these processes. Changes in m^(6)A modification levels and the expression levels of related enzymatic proteins can lead to neurological dysfunction and contribute to the development of neurological diseases. Furthermore, the proliferation and differentiation of neural stem cells, as well as nerve regeneration, are intimately linked to memory function and neurodegenerative diseases. This paper presents a comprehensive review of the roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, as well as its implications in memory and neurodegenerative diseases. m^(6)A has demonstrated divergent effects on the proliferation and differentiation of neural stem cells. These observed contradictions may arise from the time-specific nature of m^(6)A and its differential impact on neural stem cells across various stages of development. Similarly, the diverse effects of m^(6)A on distinct types of memory could be attributed to the involvement of specific brain regions in memory formation and recall. Inconsistencies in m^(6)A levels across different models of neurodegenerative disease, particularly Alzheimer's disease and Parkinson's disease, suggest that these disparities are linked to variations in the affected brain regions. Notably, the opposing changes in m^(6)A levels observed in Parkinson's disease models exposed to manganese compared to normal Parkinson's disease models further underscore the complexity of m^(6)A's role in neurodegenerative processes. The roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, and its implications in memory and neurodegenerative diseases, appear contradictory. These inconsistencies may be a

关键词： Alzheimer's disease cell self-renewal central nervous system memory microglia nerve regeneration neurodegenerative diseases neurogenesis RNA methylation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

2型糖尿病患者的焦虑、抑郁情绪分析

引用

复旦学报（医学版） 2004年第6期31卷 615-617,636页

作者：李娜江孙芳高鑫季建林花霞赵耐青复旦大学公共卫生学院卫生统计与社会医学教研室附属中山医院上海200032 复旦大学公共卫生学院卫生统计与社会医学教研室附属中山医院内分泌科上海200032 复旦大学公共卫生学院卫生统计与社会医学教研室附属中山医院心理科上海200032

目的　探讨心理因素与糖尿病患者的关系。方法　选择上海市 16 4例社区糖尿病病例和 6 2例社区正常人群进行病例对照研究 ,并采用Zung焦虑自评量表和抑郁自评量表测量研究对象的心理状况。结果　通过多元Logistic回归分析校正混杂因素... 详细信息

目的　探讨心理因素与糖尿病患者的关系。方法　选择上海市 16 4例社区糖尿病病例和 6 2例社区正常人群进行病例对照研究 ,并采用Zung焦虑自评量表和抑郁自评量表测量研究对象的心理状况。结果　通过多元Logistic回归分析校正混杂因素后 ,焦虑或抑郁为因变量时糖尿病OR分别为 15 .87(95 %CI:2 .0 0～ 12 5 .95 )和 3.18(95 %CI:1.5 9～ 6 .36 )。结论　焦虑、抑郁等心理状况与 2型糖尿病有一定关联性。

关键词： 2型糖尿病 Zung焦虑自评量表抑郁情绪患者心理状况正常人群抑郁自评量表因果关系社区目的

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Lipomatous ependymoma with ZFTA:RELA fusion-positive:A case report

引用

World Journal of Clinical Cases 2025年第1期13卷 48-55页

作者： xiao-Yu zhao Juan-Han Yu Yi-hua Wang Yi-Xin Liu Lu Xu Lin Fu Ning Yi China Medical University The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Pathology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Anshan Cancer Hospital Anshan 114000Liaoning ProvinceChina

BACKGROUND Ependymoma with lipomatous differentiation is a rare type of *** ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system *** fusion-positive lipomatous ependymoma has not been reported to *** SUMMARY We reported a case of a 15-year-old Chinese male who had a sudden convulsion lasting approximately six *** resonance imaging showed a round cystic shadow of approximately 1.9 cm×1.5 cm×1.9 cm under the right parieto-occipital *** examination showed characteristic perivascular pseudorosettes and adipose differentiation in the ***-chemical staining showed that the tumor cells were negative for cytokeratin,NeuN,Syn and p53,but positive for GFAP,vimentin and S-100 ***-ficant punctate intracytoplasmic EMA immunoreactivity was *** level of Ki-67 was about 5%.Genetic analysis revealed ZFTA:RELA fusion.A cranio-tomy with total excision of the tumor was *** follow-up time was 36 months,no evidence of disease recurrence was found in magnetic resonance *** Based on these findings,the patient was diagnosed as a ependymoma with ZFTA fusion and lipomatous *** case report provides information on the microscopic morphological features of ependymoma with ZFTA fusion and lipomatous differentiation,which can help pathologists to make a definitive diagnosis of this tumor.

关键词： Ependymoma Lipomatous Molecular classification Supratentorial ZFTA:RELA fusion Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Efficient and Stable Photoassisted Lithium-Ion Battery Enabled by Photocathode with Synergistically Boosted Carriers Dynamics

引用

NANO-MICRO LETTERS 2025年第1期17卷 1-15页

作者： Ma, Zelin Wang, Shiyao Ma, Zhuangzhuang Li, Juan zhao, Luomeng Li, Zhihuan Wang, Shiyuan Shuang, Yazhou Wang, Jiulong Wang, Fang xia, Weiwei Jian, Jie He, Yibo Wang, Junjie Guo, Pengfei Wang, Hongqiang Northwestern Polytech Univ Ctr Nano Energy Mat State Key Lab Solidificat Proc Sch Mat Sci & Engn Xian 710072 Peoples R China NPU Shaanxi Joint Lab Graphene Xian 710072 Peoples R China Northwestern Polytech Univ Sch Mat Sci State Key Lab Solidificat Proc Xian 710072 Peoples R China Northwestern Polytech Univ Engn Dept Xian 710072 Peoples R China Northwestern Polytech Univ Ctr Adv Lubricat & Seal Mat Sch Mat Sci & Engn State Key Lab Solidificat Proc Xian 710072 Peoples R China Northwestern Polytech Univ Shenzhen Res & Dev Inst Shenzhen 518063 Peoples R China Shaanxi Normal Univ Key Lab Appl Surface & Colloid Chem Shaanxi Engn Lab Adv Energy Technol Shaanxi Key Lab Adv Energy DevicesSch Mat Sci & E Xian 710119 Peoples R China

Efficient and stable photocathodes with versatility are of significance in photoassisted lithium-ion batteries (PLIBs), while there is always a request on fast carrier transport in electrochemical active photocathodes. Present work proposes a general approach of creating bulk heterojunction to boost the carrier mobility of photocathodes by simply laser assisted embedding of plasmonic nanocrystals. When employed in PLIBs, it was found effective for synchronously enhanced photocharge separation and transport in light charging process. Additionally, experimental photon spectroscopy, finite difference time domain method simulation and theoretical analyses demonstrate that the improved carrier dynamics are driven by the plasmonic-induced hot electron injection from metal to TiO2, as well as the enhanced conductivity in TiO2 matrix due to the formation of oxygen vacancies after Schottky contact. Benefiting from these merits, several benchmark values in performance of TiO2-based photocathode applied in PLIBs are set, including the capacity of 276 mAh g(-1 ) at 0.2 A g(-1 )under illumination, photoconversion efficiency of 1.276% at 3 A g(-1 ), less capacity and Columbic efficiency loss even through 200 cycles. These results exemplify the potential of the bulk heterojunction strategy in developing highly efficient and stable photoassisted energy storage systems.

关键词： Photoassisted lithium-ion batteries Bulk heterojunction Carrier dynamics TiO2 nanofiber Plasmonic metal nanocrystals

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：