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Chinese Physics B 2018年第9期27卷 128-136页

作者： Zhi-hua shao Xue-Guang Qiao feng-Yi Chen and Qiang-Zhou Rongt School of Physics Northwest UniversityXi an 710069China

An ultrasonic sensitivity-improved fiber-optic Fabry-Perot interferometer （FPI） is proposed and employed for ultra- sonic imaging of seismic physical models （SPMs）. The FPI comprises a flexible ultra-thin gold film and the end face of a graded-index multimode fiber （MMF）, both of which are enclosed in a ceramic tube. The MMF in a specified length can collimate the diverged light beam and compensate for the light loss inside the air cavity, leading to an increased spectral fringe visibility and thus a steeper spectral slope. By using the spectral sideband filtering technique, the collimated FP1 shows an improved ultrasonic response. Moreover, two-dimensional images of two SPMs are achieved in air by recon- structing the pulse-echo signals through using the time-of-flight approach. The proposed sensor with easy fabrication and compact size can be a good candidate for high-sensitivity and high-precision nondestructive testing of SPMs.

关键词： fiber-optic sensor Fabry-Perot interferometer seismic physical model

Research status and prospect of direct strip casting manufactured lowcarbon microalloyed steel

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Journal of Iron and Steel Research International 2022年第1期29卷 17-33页

作者： Shuai Xu shao-hua Li Shui-ze Wang Jun-heng Gao Rui Cao Qing-xiao feng hua-long Li Xin-ping Mao Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijing 100083China Jiangsu(ShaGang)Iron and Steel Research Institute Zhangjiagang 215625JiangsuChina

Direct strip casting(DSC)is one of the cutting-edge technologies for the steel industry in the twenty-first *** the background of carbon peak and carbon neutrality,DSC technology has a bright future of applications as it requires less production time and space with reduced energy *** to its sub-rapid cooling rate during solidification and low reduction during hot rolling,DSC process exhibits a series of unique physical metallurgy *** process characteristics of DSC process and the microstructural evolution during the thermomechanical processing of low-carbon microalloyed steel are *** effects of hot rolling,cooling,coiling temperatures and microalloying elements on the microstructure and mechanical properties are then ***,the future development orientations of DSC technology are suggested to fully utilize its unique features for the enhancement of its competitiveness and for the promotion of carbon neutrality of the steel industry.

关键词： Direct strip casting Low-carbon microalloyed steel Hot rolling Coiling Acicular ferrite

Decreased levels of phosphorylated synuclein in plasma are correlated with poststroke cognitive impairment

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Neural Regeneration Research 2025年第9期20卷 2598-2610页

作者： Yi Wang Yuning Li Yakun Gu Wei Ma Yuying Guan Mengyuan Guo Qianqian shao Xunming Ji Jia Liu Department of Clinical Laboratory Beijing Bo’ai HospitalChina Rehabilitation Research CenterCapital Medical UniversityBeijingChina Beijing Institute of Brain Disorders Laboratory of Brain DisordersMinistry of Science and TechnologyCollaborative Innovation Center for Brain DisordersBeijing Advanced Innovation Center for Big Data-based Precision MedicineCapital Medical UniversityBeijingChina Department of Neurosurgery Xuanwu HospitalCapital Medical UniversityBeijingChina

Poststro ke cognitive impairment is a major secondary effect of ischemic stroke in many patients;however,few options are available for the early diagnosis and treatment of this *** aims of this study were to(1)determine the specific relationship between hypoxic andα-synuclein during the occur of poststroke cognitive impairment and(2)assess whether the serum phosphorylatedα-synuclein level can be used as a biomarker for poststro ke cognitive *** found that the phosphorylatedα-synuclein level was significantly increased and showed pathological aggregation around the cerebral infa rct area in a mouse model of ischemic *** addition,neuronalα-synuclein phosphorylation and aggregation were observed in the brain tissue of mice subjected to chronic hypoxia,suggesting that hypoxia is the underlying cause ofα-synuclein-mediated pathology in the brains of mice with ischemic *** phosphorylatedα-synuclein levels in patients with ischemic stroke were significantly lower than those in healt hy subjects,and were positively correlated with cognition levels in patients with ischemic ***,a decrease in serum high-density lipoprotein levels in stroke patie nts was significantly correlated with a decrease in phosphorylatedα-synuclein *** ischemic stroke mice did not show significant cognitive impairment or disrupted lipid metabolism 14 days after injury,some of them exhibited decreased cognitive function and reduced phosphorylatedα-synuclein *** together,our results suggest that serum phosphorylatedα-synuclein is a potential biomarker for poststroke cognitive impairment.

关键词： biomarker high-density lipoprotein ischemic stroke phosphorylatedα-synuclein poststroke cognitive impairment

Selective killing effect of oxytetracycline,propafenone and metamizole on A549 or Hela cells

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Chinese Journal of Cancer Research 2013年第6期25卷 662-670页

作者： Jinhui shao Guihua feng Department of Histology and Embryology School of MedicineHubei University of Art and Science

Objective： To determine the selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells. Methods： Proliferation assay, lactate dehydrogenase （LDH） assay, apoptosis detecting, flow cytometry and western blot were performed. Results： It was found that treatment with propafenone at the concentration of 0.014 g/L or higher for 48 h could induce apoptosis in Hela cells greatly, while it was not observed in oxytetracycline and metamizole at the concentration of 0.20 g/L for 48 h. Oxytetracycline, propafenone and metamizole all displayed evident inhibitory effects on the proliferation of A549 cells. The results of LDH assay demonstrated that the drugs at the test range of concentration did not cause necrosis in the cells. Propafenone could elevate the protein level of P53 effectively （P〈0.01）. Conclusions： Oxytetracycline, propafenone and metamizol （dipyrone） all displayed evident inhibitory effects on the proliferation of A549 cells. Propafenone also displayed evident inhibitory effects on the proliferation of Hela cells.

关键词： Cancer drug oxytetracycline propafenone metamizol

Effect of silk sericin on morphology and structure of calcium carbonate crystal

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Frontiers of Materials Science 2013年第2期7卷 177-183页

作者： Rui-Bo ZHAO hua-feng HAN shao DING Ze-Hao LI Xiang-Dong KONG Xinyuan Institute of Medicine and Biotechnology College of Life Sciences Zhejiang Sci-Tech University Hangzhou 310018 China College of Materials and Textile Zhejiang Sci-Tech University Hangzhou 310018 China

In this paper, silk sericin was employed to regulate the mineralization of calcium carbonate （CaC03）. CaCO3 composite particles were prepared by the precipita- tion reaction of sodium carbonate with calcium chloride solution in the presence of silk sericin. The as-prepared samples were collected at different reaction time to study the crystallization process of CaCO3 by scanning electron microscopy （SEM）, Fourier transform infrared spectroscopy （FTIR）, thermogravimetric analysis （TGA） and X-ray diffraction （XRD）. The results showed that silk sericin significantly affected the morphology and crystallographic polymorph of CaCO3. With increasing the reaction time, the crystal phase of CaCO3 transferred from calcite dominated to vaterite dominated mixtures, while the morphology of CaCO3 changed from disk-like calcite crystal to spherical vaterite crystal. These studies showed the potential of silk sericin used as a template molecule to control the growth of inorganic crystal.

关键词： silk sericin calcium carbonate (CaC03) calcite vaterite biomineralization

Magnetic Reconnection Under Solar Coronal Conditions with the 2.5D AMR Resistive MHD Model

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Chinese Physics Letters 2011年第8期28卷 348-351页

作者： ZHANG shao hua feng Xue-Shang WANG Yi YANG Li-Ping SIGMA Weather Group State Key Laboratory for Space WeatherCenter for Space Science and Applied ResearchChinese Academy of SciencesBeijing 100190 College of Earth Sciences Graduate University of Chinese Academy of SciencesBeijing 100049

The evolutionary process of magnet ic reconnect ion under solar coronal conditions is investigated with our recently developed 2.5D adaptive mesh refinerment(AMR)resistive magneto hydrodynamics (MHD)*** reveal the successive fragmentation and merging of plasmoids in a long-thin current sheet with Lundquist nurmber Rm=5.0× 10^(4).It is found that several big magnetic islands are formed event ually,with many slow-mode shocks bounding around the outflow *** multi-scale hier archicallike struct ures of the magnetic reconnect ion are well resolved by the model and the AMR technique of the model can capture many fine pictures(e.g,the near-singular difusion regions)of the development and simultaneously it can save a great deal of computing resources.

关键词： 2.5D Solar MHD

Nonlinear Internal Damping of Wave Equations with Variable Coefficients

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Acta Mathematica Sinica,English Series 2004年第6期20卷 1057-1072页

作者： shao Ji feng De Xing feng Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100080P.R.China Institute of Systems Science Academy of Mathematics and Systems ScienceChinese Academy of Sciences

For wave equations with variable coefficients on regions which are not necessarily smooth, we study the energy decay rate when a nonlinear damping is applied on a suitable subrigion.

关键词： Wave equations Energy decay rate Nonlinear internal damping Riemannian manifold

Effect of Nitric Oxide on Alleviating Cadmium Toxicity in Rice (Oryza sativa L.)

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Journal of Integrative Agriculture 2013年第9期12卷 1540-1550页

作者： ZHAO Xiu-feng CHEN Lin Muhammad I A Rehmani WANG Qiang-sheng WANG shao-hua HOU Peng-fu LI Gang-hua DING Yan-feng College of Agriculture Nanjing Agricultural University/Key Laboratory of Crop Physiology and Ecology in Southern ChinaMinistry of Agriculture

Nitric oxide （NO） is a gaseous signaling molecule in plants that plays a key role in mediating a wide range of physiological processes and responses to biotic and abiotic stresses. The present study was conducted to investigate the effects of the exogenous application of sodium nitroprusside （SNP）, an NO donor, on cadmium （Cd）-induced oxidative stress and Cd uptake in rice plants. Rice plants were exposed to Cd stress （0.2 mmol L^-1 CdC12） and different concentrations of SNP （0.05, 0.1, 0.2, and 0.4 mmol L^-1）. A SNP concentration of 0.1 mmol L^-1 （SNP 10） significantly reduced the Cd-induced decrease in shoot and root dry weights and leaf chlorophyll concentrations. The addition of NO also reduced the malondialdehyde （MDA）, hydrogen peroxide （H202） and ascorbic acid （ASA） concentrations. However, the reduction in glutathione （GSH） concentration was inhibited by NO treatment. Moreover, NO prevented the Cd-induced increase in antioxidative enzyme activity. The amount of Cd accumulation in rice plants was also influenced by the addition of NO. The NO supplied by the SNP enhanced the Cd tolerance of the rice by increasing the Cd uptake by the roots and decreasing the Cd accumulation by the shoots. However, the application of potassium ferrocyanide （Cd＋Fe） or sodium nitrate and nitrite （Cd＋N）（without NO release）, did not exhibit the effects of the SNP. Furthermore, the effects of the SNP were reversed by the addition of hemoglobin （an NO scavenger）. Our results suggested that exogenous NO was involved in the resistance of rice to Cd-toxicity.

关键词： cadmium toxicity nitric oxide oxidative stress Oryza sativa L.

基质金属蛋白酶-1与冠状动脉斑块稳定性的相关研究

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中国心血管病研究 2007年第12期5卷 889-891页

作者：侯旭敏刘华关韶峰仇兴标陈晖方唯一上海胸科医院心内科上海市200030

目的探讨冠心病患者血基质金属蛋白酶-1(MMP-1)的浓度及与冠状动脉斑块特点的相关性。方法127例患者通过冠脉造影,分为稳定斑块组(72例)和不稳定斑块组(100例),比较两组患者基本特征(年龄、性别)、危险因素(高血压、高脂血症、糖尿病、... 详细信息

目的探讨冠心病患者血基质金属蛋白酶-1(MMP-1)的浓度及与冠状动脉斑块特点的相关性。方法127例患者通过冠脉造影,分为稳定斑块组(72例)和不稳定斑块组(100例),比较两组患者基本特征(年龄、性别)、危险因素(高血压、高脂血症、糖尿病、吸烟、家族史)以及实验室和辅助检查(心脏超声、血脂指标、C-反应蛋白、MMP-1)的差异。结果两组间的性别、年龄、危险因素差异无统计学意义。不稳定斑块组与稳定斑块组比较,左室射血分数(EF)较低(0.55±0.08和0.60±0.04),CRP水平较高[(16.2±3.60)mmol/L和(1.82±2.09)mmol/L],MMP-1浓度较大[(3.14±2.76)ng/ml和(2.17±1.04)ng/ml],差异有统计学意义(P<0.05)。多因素分析显示,CRP(β系数=0.193,P=0.049)和MMP-1(β系数=0.216,P=0.046)的水平为独立预测因素。结论MMP-1与冠脉斑块不稳定密切相关,可作为评价冠脉斑块不稳定性的独立预测因素,具有良好的临床应用前景。

关键词：金属内肽酶类斑块稳定性冠状动脉疾病

A Fast Solution Method to Economic Dispatch Type Problem

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Journal of Modern Power Systems and Clean Energy 2021年第5期9卷 1227-1232页

作者： Chenjia feng Chengcheng shao Xifan Wang Life School of Electrical Engineering Xi’an Jiaotong UniversityXi’an 710049China

Economic dispatch(ED)aims to minimize the generation cost subject to power balance *** is extensively used in power system operation and *** problem as well as other problems with the same formulation are named as ED-type problems in this letter and a fast solution method is *** proposed method is achieved by solving a series of relaxed *** a closed-form solution for the relaxed ED-type problems,it is demonstrated that the proposed method consumes far less computing time and memory space than the off-the-shelf solvers and other quadratic programming(QP)***,the effectiveness and computational efficiency of the proposed method are verified by the case studies,which shows the great potential in power system planning and operation.

关键词： Fast solution economic dispatch closed-form solution quadratic programming