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“以本为本,四个回归”为原则的“新能源技术”课程教学模式探索

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教育教学论坛 2025年第2期 145-148页

作者：周丹丹胡广涛李国杰李凡榆林学院能源工程学院陕西榆林719000

“新能源技术”课程是电厂能源与动力工程专业的专业拓展课,课程具有前沿性、应用性、多样性、实践性和开放性的特点。为培养能源专业的复合创新型人才,课程以“以本为本,四个回归”为出发点,通过改变传统教学方式、师生共建新能源课件... 详细信息

“新能源技术”课程是电厂能源与动力工程专业的专业拓展课,课程具有前沿性、应用性、多样性、实践性和开放性的特点。为培养能源专业的复合创新型人才,课程以“以本为本,四个回归”为出发点,通过改变传统教学方式、师生共建新能源课件、理论结合实践等方式提高学生的学习积极性和主动性。通过教学实践表明,以学生为中心的教学模式能够激发学生在学习过程中的主动性与学习兴趣,能够明显提升“新能源技术”课程教学效果。

关键词：新能源技术 “以本为本” “四个回归” 教学改革思政

High-precision tip positioning composite feedforward control of linear colocated motion systems with Bi-Loop iterative feedforward tuning

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Science China(Technological Sciences) 2025年第2期68卷 153-166页

作者： Junyu hu Yourui tao Shanhu LI Xu HAN College of Mechanical and Vehicle Engineering Hunan UniversityChangsha 410082China State Key Laboratory of Reliability and Intelligence of Electrical Equipment Hebei University of TechnologyTianjin 300130China

To enhance the tip positioning accuracy and robustness against disturbances of linear colocated motion systems,a novel composite feedforward(COMFF)control with Bi-Loop iterative feedforward tuning(IFFT)is *** tip positioning error consists of the coupled tip residual vibration and linear motor tracking *** the influence of nonlinear friction and load flexibility,the topology of COMFF is designed as decoupled structures so that COMFF can suppress the tip residual vibration and compensate for the linear motor tracking error ***,Bi-Loop IFFT is built to improve the robustness of COMFF in high-precision motor tracking *** the state space of the linear motor tracking error based on the projection theorem,two loops are performed in parallel along the iteration *** is the P-type iteration loop that drives linear motor tracking errors to converge to the zero *** other is the observation loop constructed by the recursive least square with forgetting factors to accelerate the P-type iteration *** by the P-type iteration loop with the aid of the observation loop,the proposed COMFF is integrated with fast convergence and high robustness when confronted with model *** effectiveness of the proposed COMFF combined with Bi-Loop IFFT is validated by experiments.

关键词： composite feedforward(COMFF)control Bi-Loop iterative feedforward tuning(Bi-Loop IFFT) colocated motion systems nonlinear friction flexible load

Unraveling brain aging through the lens of oral microbiota

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Neural Regeneration Research 2025年第7期20卷 1930-1943页

作者： Qinchao hu Si Wang Weiqi Zhang Jing Qu guang-hui Liu State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Hospital of Stomatology Guanghua School of StomatologyGuangdong Provincial Key Laboratory of StomatologySun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Advanced Innovation Center for human Brain Protection and National Clinical Research Center for Geriatric Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Aging Translational Medicine Center International Center for Aging and CancerBeijing Municipal Geriatric Medical Research CenterXuanwu HospitalCapital Medical UniversityBeijingChina CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijingChina University of Chinese Academy of Sciences BeijingChina Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijingChina Aging Biomarker Consortium BeijingChina State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Beijing Institute for Stem Cell and Regenerative Medicine BeijingChina

The oral cavity is a complex physiological community encompassing a wide range of *** of oral microbiota can lead to various oral infectious diseases,such as periodontitis and tooth decay,and even affect systemic health,including brain aging and neurodegenerative *** studies have highlighted how oral microbes might be involved in brain aging and neurodegeneration,indicating potential avenues for intervention *** this review,we summarize clinical evidence demonstrating a link between oral microbes/oral infectious diseases and brain aging/neurodegenerative diseases,and dissect potential mechanisms by which oral microbes contribute to brain aging and *** also highlight advances in therapeutic development grounded in the realm of oral microbes,with the goal of advancing brain health and promoting healthy aging.

关键词： Alzheimer's disease brain aging multiple sclerosis neurodegeneration neurodegenerative diseases oral microbiota Parkinson's disease periodontitis bacteria Porphyromonas gingivalis

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一种在线自适应控制马氏链的强化学习算法

云南大学学报（自然科学版） 2000年第1期22卷 9-12页

作者：胡光华胡光涛云南大学数学系云南昆明650091 云南大学统计系云南昆明650091

讨论平均准则控制马氏链的强化学习算法.目的是寻找使得长期每阶段期望平均报酬最大的最优控制策略.由于事先未知状态转移矩阵及报酬向量,故必需使用自适应控制方法.通过引入称之为行动器和评判器的神经网络构造,使得学习单元在不断学习... 详细信息

讨论平均准则控制马氏链的强化学习算法.目的是寻找使得长期每阶段期望平均报酬最大的最优控制策略.由于事先未知状态转移矩阵及报酬向量,故必需使用自适应控制方法.通过引入称之为行动器和评判器的神经网络构造,使得学习单元在不断学习中,最终能发现最优策略.行动器的参数在学习中不断被修正,每一时刻的参数的值均对应着一个随机控制策略.

关键词：强化学习自适应评判马氏链控制问题

Health risks of rare earth elements exposure:Impact on mitochondrial DNA copy number and micronucleus frequency

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Journal of Environmental Sciences 2025年第5期151卷 150-160页

作者： Shiyi Hong Yali Zhang Qiaojian Zhang Zekang Su Guiping hu Li Wang Shanfa Yu Xiaojun Zhu guang Jia Department of Occupational and Environmental Health Sciences School of Public HealthPeking UniversityBeijing 100083China School of Engineering Medicine and Beijing Advanced Innovation Center for Big Data-Based Precision Medicine Beihang UniversityBeijing 100083China Department of Toxicology School of Public HealthBaotou Medical CollegeBaotouInner Mongolia 014040China Henan Institute for Occupational Medicine Zhengzhou 450052China National Center for Occupational Safety and Health Beijing 102308China Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety School of Public HealthPeking UniversityBeijing 100083China

Toxic effects in terms of mitochondria and hereditary substances have been characterized in vitro for individual rare earth elements,while,the joint effects of mixed elements exposure in the population remain *** on the Occupational Chromate Exposure Dynamic Cohort of China,this study investigated the relationship between 15 blood rare earth elements(cerium,dysprosium,erbium,europium,gadolinium,holmium,lanthanum,lutetium,neodymium,praseodymium,samarium,terbium,thulium,yttrium,and ytterbium)and mitochondrial DNA copy number(MtDNACN)as well as peripheral blood lymphocyte micronucleus frequency(MNF).The elastic net was used to select elements highly correlated with effect indicators,whose dose-response relationships were further illustrated by restricted cubic *** kernel regressionwas employed to explore the combined effects of elements and the contributions of single *** results showed that most rare earth elementswere positively correlatedwith effect indicators,with yttrium showing the strongest association(β(95%CI):0.139(0.1089–0.189)for MtDNACN,0.937(0.345–1.684)for MNF).In the mixed exposure model,with the exposure level fixed at the 50th percentile as the reference,the effect estimates on MtDNACN and MNF increased by 0.228 and 0.598 units,respectively,at the 75th *** single effect analysis implied that yttrium,lanthanum and terbium contributed the most to the elevation of MtDNACN,while yttrium posed the highest risk for genetic damage,accordingly,we provided recommendations to prioritize these elements of *** addition,we observed a chief mediating effect of MtDNACN on the elevation of MNF caused by lanthanum,whereas further mechanistic exploration is required to confirm this finding.

关键词： Rare earth elements Mitochondrial DNA copy number Micronucleus frequency Mixed effect

Bioaccessibility and health risk assessment of hydrophobic organic pollutants in soils from four typical industrial contaminated sites in China

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Journal of Environmental Sciences 2025年第1期147卷 282-293页

作者： Shi-Ping Ou Xiao-Liang Liao Zi-tao huang Yan-Cong hu Zongwei Cai Zhi-Feng Chen guangdong Key Laboratory of Environmental Catalysis and Health Risk Control Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and HealthSchool of Environmental Science and EngineeringGuangdong University of TechnologyGuangzhou 510006China State Key Laboratory of Environmental and Biological Analysis Department of ChemistryHong Kong Baptist UniversityHong Kong 999077China

There have been reports of potential health risks for people from hydrophobic organic pollutants,such as polycyclic aromatic hydrocarbons(PAHs),polychlorinated hydrocarbons(PCHs),and organophosphate flame retardants(OPFRs).When a contaminated site is used for residential housing or public utility and recreation areas,the soil-bound organic pollutantsmight pose a threat to human *** this study,we investigated the contamination profiles and potential risks to human health of 15 PAHs,6 PCHs,and 12 OPFRs in soils from four contaminated sites in *** used an in vitro method to determine the oral bioaccessibility of soil *** PAHswere found at concentrations ranging from26.4 ng/g to 987 ng/***(0.27-14.3 ng/g)and OPFRs(6.30-310 ng/g)were detected,but at low levels compared to earlier *** levels of PAHs,PCHs,and OPFRs released from contaminated soils into simulated gastrointestinal fluids ranged from 1.74%to 91.0%,2.51%to 39.6%,and 1.37%to 96.9%,*** on both spiked and unspiked samples,we found that the oral bioaccessibility of pollutantswas correlated with their logKow andmolecularweight,and the total organic carbon content and pH of *** in 13 out of 38 contaminated soil samples posed potential high risks to *** considering oral bioaccessibility,nine soils still posed potential risks,while the risks in the remaining soils became *** contribution of this paper is that it corrects the health risk of soil-bound organic pollutants by detecting bioaccessibility in actual soils from different contaminated sites.

关键词： Contaminated soil Hydrophobic organic pollutant Polycyclic aromatic hydrocarbon Oral bioaccessibility Risk assessment

Construction of 3D porous Cu_(1.81)S/nitrogen-doped carbon frameworks for ultrafast and long-cycle life sodium-ion storage

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 191-200页

作者： Chen Chen Hongyu Xue Qilin hu Mengfan Wang Pan Shang Ziyan Liu tao Peng Deyang Zhang Yongsong Luo Key Laboratory of Microelectronics and Energy of Henan Province Henan Joint International Research Laboratory of New Energy Storage TechnologyCollege of Physics and Electronic EngineeringXinyang Normal UniversityXinyang 464000China School of Physics and Electronic Engineering Nanyang Normal UniversityNanyang 473061China

Transition metal sulfides have great potential as anode mterials for sodium-ion batteries(SIBs)due to their high theoretical specific ***,the inferior intrinsic conductivity and large volume variation during sodiation-desodiation processes seriously affect its high-rate and long-cyde performance,unbeneficial for the application as fast-charging and long-cycling SIBs ***,the three-dimensional porous Cu_(1.81)S/nitrogen-doped carbon frameworks(Cu_(1.81)S/NC)are synthesized by the simple and facile sol-gel and annealing processes,which can accommodate the volumetric expansion of Cu_(1.81)S nanoparticles and accelerate the transmission of ions and electrons during Na^(+)insertion/extraction processes,exhibiting the excellent rate capability(250.6 mA·g^(-1)at 20.0 A·g^(-1))and outstanding cycling stability(70% capacity retention for 6000 cycles at 10.0 A·g^(-1))for ***,the Na-ion full cells coupled with Na_(3)V_(2)(PO_(4))_(3)/C cathode also demonstrate the satisfactory reversible specific capacity of 330.5 mAh·g^(-1)at 5.0 A·g^(-1)and long-cycle performance with the 86.9% capacity retention at 2.0 A·g^(-1)after 750 *** work proposes a promising way for the conversionbased metal sulfides for the applications as fast-charging sodium-ion battery anode.

关键词： copper sulfide nanoparticles porous carbon framework fast charging long-cycle performance sodium-ion full batteries

17α-methyltestosterone induced hepatocyte apoptosis through endoplasmic reticulum stress in Takifugu fasciatus

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Journal of Oceanology and Limnology 2025年第1期43卷 219-231页

作者： Xuanyin CHEN Sheng LUO Yanfang LI Rui LI Xiaojun LI Zhengyang hu Shaowu YIN tao WANG College of Marine Science and Engineering Jiangsu Province Engineering Research Center for Aquatic Animals Breeding and Green Efficient Aquacultural TechnologyNanjing Normal UniversityNanjing 210023China Co-Innovation Center for Marine Bio-Industry Technology of Jiangsu Province Lianyungang 222005China

17α-methyltestosterone(17α-MT)is an emerging pollutant,which is harmful to the endocrine system and reproduction of *** investigated the effects of different concentrations of 17α-MT(0,5,30,60,and 100 mg/kg)on endoplasmic reticulum stress(ERS)and apoptosis in the liver of Takifugu *** show that:(1)with the increase of 17α-MT treatment concentration,liver transaminases(alanine aminotransferase;aspartate aminotransferase)and the mRNA expression of ERS marker genes(glucose-regulated protein 78;calreticulin)of *** were significantly increased compared with the control group(P<0.05);(2)the activity of succinate dehydrogenase(SDH),Caspase3 and Caspase9 in the liver of *** increased with the increase of 17α-MT concentration compared with the control group(P<0.05);(3)by using 4-phenylbutyricacid(4-PBA)inhibitors to stimulate ERS through in vitro experiments,the expression of ERS and apoptosis-related genes significantly decreased(P<0.05),and the apoptosis rate of *** hepatocytes was significantly inhibited(P<0.05)under 17α-MT *** study confirmed that ERS played an important role in the induction of apoptosis in the hepatocytes of ***,which enriched the ecotoxicological information of environmental androgens.

关键词： 17α-methyltestosterone Takifugu fasciatus liver endoplasmic reticulum stress apoptosis

Polymer-based smart fibers and textiles for wearable electronics

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Science China(Technological Sciences) 2025年第1期68卷 81-116页

作者： Sanming hu Li WANG Zaixian YUAN Kun CHEN Wei PENG Hai YIN Zhijun SHI guang YANG School of Biomedical Engineering and Imaging Xianning Medical CollegeHubei University of Science and TechnologyXianning 437100China College of Life Science and Technology Huazhong University of Science and TechnologyWuhan 430074China Wuhan Branch of the National Science Library Chinese Academy of SciencesWuhan 430071China

Smart fibers and textiles have attracted considerable interest for application in wearable devices because of their advantages of being human-friendly,lightweight,flexible,and *** addition,they are considered to have potential applications in health monitoring,energy management,and human-machine interaction *** and polymer fibers,with excellent mechanical strength,wrinkle resistance,and heat resistance,are widely used to fabricate smart fibers and ***,a comprehensive overview of polymer-based fibers and textiles is ***,we review the design principles of various polymer-based smart textiles,including textile-based sensors,energy capture and storage textiles,and computation and display ***,materials used for preparing polymer-based smart fibers,such as metals,carbon-based materials,and natural and synthetic polymers,particularly conductive polymers,are *** addition,this review summarizes key technologies used for preparing smart fibers and the conventional structures of smart ***,the applications of smart textiles in personal health monitoring,thermal management,energy capture and storage,and computation and displays are ***,the current challenges,limitations,and future trends of smart fibers and textiles are discussed.

关键词： polymers smart fibers smart textiles wearable electronics health management