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从瘀论治盆腔炎性疾病后遗症

中医学报 2024年第7期39卷 1437-1441页

作者：王草胡小芳河南中医药大学第一临床医学院河南郑州450000 河南中医药大学第一附属医院河南郑州450000

盆腔炎性疾病后遗症是妇科常见疾病,是由盆腔炎性疾病反复发作进展而来。虽然盆腔炎性疾病后遗症的中医病因病机较为复杂,但总以“瘀”为疾病之根本,瘀血既是盆腔炎性疾病的病理产物,亦是致病因素,贯穿疾病发展的始终。在临床诊疗盆腔... 详细信息

盆腔炎性疾病后遗症是妇科常见疾病,是由盆腔炎性疾病反复发作进展而来。虽然盆腔炎性疾病后遗症的中医病因病机较为复杂,但总以“瘀”为疾病之根本,瘀血既是盆腔炎性疾病的病理产物,亦是致病因素,贯穿疾病发展的始终。在临床诊疗盆腔炎性疾病后遗症的过程中,应辨证论治,重视活血化瘀之法的应用,并将其贯穿于疾病防治的始终,以活血化瘀为主,配合清热利湿、疏肝行气、温经散寒、益气健脾、补肾活血等方法治疗,不仅能有效缓解患者临床症状,同时能提高患者免疫力,降低盆腔炎性疾病的复发率。

关键词：盆腔炎性疾病后遗症从瘀论治清热利湿化瘀疏肝行气化瘀温经化瘀益气化瘀补肾化瘀

Bayesian neural network enhancing reliability against conductance drift for memristor neural networks

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Science China(Information Sciences) 2021年第6期64卷 100-111页

作者： Yue ZHOU xiaofang hu Lidan WANG Shukai DUAN College of Electronics and Information Engineering Southwest University College of Artificial Intelligence Southwest University

The hardware implementation of neural networks based on memristor crossbar array provides a promising paradigm for neuromorphic computing. However, the existence of memristor conductance drift harms the reliability of the deployed neural network, which seriously hinders the practical application of memristor-based neuromorphic computing. In this paper, the impact of different types of conductance drift on the weight realized by memristors is investigated and analyzed. Then, utilizing the weight uncertainty introduced by conductance drift, we propose a weight optimization method based on the Bayesian neural network, which can greatly improve the network performance. Furthermore, an ensemble approach is proposed to enhance network reliability without increasing training cost or crossbar array resources. Finally, the effectiveness of the proposed scheme is verified through a series of experiments. In addition, the proposed scheme can be easily integrated into the implementation of neuromorphic computing, which can provide a better guarantee for its large-scale application.

关键词： conductance drift neuromorphic computing Bayesian neural network memristor crossbar array network reliability

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基于数字体积相关的应变先验损伤识别方法

实验力学 2024年第4期39卷 413-422页

作者：仓娇青肖宇苏勇王鸿翰胡小方许峰中国科学技术大学中国科学院材料力学行为和设计重点实验室安徽合肥230026 安徽医科大学生物医学工程学院安徽合肥230032

研究材料内部的破坏失效过程,揭示内部损伤演化机制,是预防断裂失效的关键。计算机断层扫描技术(Computed tomography, CT)可以进行内部损伤演化过程的三维表征,为研究材料内部损伤演化机制提供支撑。然而CT图像中损伤演化的定量识别提... 详细信息

研究材料内部的破坏失效过程,揭示内部损伤演化机制,是预防断裂失效的关键。计算机断层扫描技术(Computed tomography, CT)可以进行内部损伤演化过程的三维表征,为研究材料内部损伤演化机制提供支撑。然而CT图像中损伤演化的定量识别提取,面临着损伤特征弱信号被图像中复杂结构信号湮没的难题。本文提出引入力学参量引导神经网络的思路,将基于数字体积相关(Digital volume correlation, DVC)获得的三维应变场作为力学参量先验信息,引导并约束网络训练,从而实现裂纹的识别提取。通过实际CT实验数据定量评价并验证了该方法可以提高微小裂纹识别精确率,减少识别错误率。

关键词： CT图像数字体积相关应变内部损伤识别神经网络

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山水人和:王跃文乡土小说的“人居”叙事

衡阳师范学院学报 2024年第4期45卷 98-105页

作者：胡晓芳任美衡衡阳师范学院文学院湖南衡阳421008

王跃文的乡土小说反映了当代湖南农村的社会面貌,揭示了湖南乡民的内心世界。王跃文乡土小说的“人居”叙事展现了人与自然、人与社会、人与自我的复杂关系,体现了“山、水、人”三者和合共处的显著特点。王跃文乡土小说的“人居”叙事... 详细信息

王跃文的乡土小说反映了当代湖南农村的社会面貌,揭示了湖南乡民的内心世界。王跃文乡土小说的“人居”叙事展现了人与自然、人与社会、人与自我的复杂关系,体现了“山、水、人”三者和合共处的显著特点。王跃文乡土小说的“人居”叙事既有充分的现实基础,也是对中国文化传统的“山水情结”和湖南文学传统的“山水基因”的眷恋与传承。王跃文乡土小说的“人居”叙事具有鲜明的时代价值:引发人们对现代社会人的生存状态的关切;延续人们对理想的社会图景的追慕;启发人们对舶来的“现代性”构想的反思。对王跃文乡土小说的“人居”叙事进行研究,有助于我们进一步理解王跃文乡土小说的文学价值与思想价值。

关键词：王跃文乡土小说 “人居”叙事山水人和

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游离DNA检测在结核性胸膜炎中的诊断价值

中国热带医学 2024年第2期24卷 162-165,195页

作者：程亮华少鹏姜艳平贾秀杰胡小芳赵新国无锡市第五人民医院结核科江苏无锡214005

目的评价结核分枝杆菌游离核酸检测技术(cell-free Myobacterium tuberculosis DNA test,CF-TB)在结核性胸膜炎中的诊断价值。方法对2022年无锡市第五人民医院住院的71例结核性胸膜炎患者和35例非结核性胸膜炎患者的相关检测数据分析,... 详细信息

目的评价结核分枝杆菌游离核酸检测技术(cell-free Myobacterium tuberculosis DNA test,CF-TB)在结核性胸膜炎中的诊断价值。方法对2022年无锡市第五人民医院住院的71例结核性胸膜炎患者和35例非结核性胸膜炎患者的相关检测数据分析,将胸腔积液样本行结核分枝杆菌培养、结核分枝杆菌及利福平耐药实时荧光定量核酸扩增检测技术(GeneXpert Mycobacterium tuberculosis/rifampicin resistance,GeneXpert MTB/RIF)、CF-TB和腺苷脱氨酶(adenosine deaminase,ADA)检测,血样本行结核感染T细胞斑点试验(T-cell spotting test,***)检测,应用受试者工作特征曲线(receiver operator characteristic curve,ROC)取胸水CF-TB最佳临界值,并比较CF-TB与其他检测方法的诊断性能。使用SPSS 22.0软件进行数据分析,以P<0.05为差异具有统计学意义。结果通过ROC曲线分析发现胸水CF-TB诊断结核性胸膜炎的最佳Ct值为38.489,其灵敏度、特异度分别为91.5%和97.1%,而***与胸水ADA诊断结核性胸膜炎的灵敏度、特异度、阳性预测值、阴性预测值、准确度分别为86.0%、71.4%、86.0%、71.4%、81.1%和55.0%、91.4%、92.9%、50.8%、67.0%,均低于CF-TB的诊断效能。此外,胸水CF-TB诊断结核性胸膜炎的特异度(97.1%)低于GeneXpert MTB/RIF(100.0%)和结核分枝杆菌培养(100.0%),差异无统计学意义,但其灵敏度(91.5%)高于GeneXpert MTB/RIF(19.7%)和结核分枝杆菌培养(28.2%),差异有统计学意义(P<0.001)。结论CF-TB与传统的结核性胸膜炎诊断金标准相比,其灵敏度更高,且特异度优于结核免疫学检查法,因此,CF-TB可以与其他传统检测方法互补,用于结核性胸膜炎的辅助诊断。

关键词：结核性胸膜炎游离DNA 诊断

Preparation and Characterization of Single-Phase Perovskite La_(0.6)Sr_(0.4)Co_(0.8)Fe_(0.2)O_(3-δ)

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Journal of Natural Gas Chemistry 2006年第1期15卷 58-62页

作者： Wenhui Yuan xiaofang hu Li Li College of Chemical Engineering and Energy South China University of Technology Guangdong Key Laboratory of Green Chemicals Guangzhou 510640 China

Single-phase perovskite La0.6Sr0.4Co0.8Fe0.2O3-δ has been successfully prepared by using citrate-EDTA complexation method at relatively low calcination temperature. The structure and thermal decomposition process of the complex precursor have been investigated by means of differential scanning calorimetry-thermal gravimetric analysis （DSC/TGA）, X-ray diffraction （XRD）, and Fourier transform infrared spectroscopic （FT-IR） measurements. The precursor decomposed completely and started to form perovskite-type oxide above 420 ℃ according to the differential scanning calorimetry （DSC） and thermal gravimetric analysis （TGA） results. Single-phase perovskite La0.6Sr0.4Co0.8Fe0.2O3-δ obtained has been confirmed from the XRD pattern, and no peak of SrCO3 was found by XRD of the oxides synthesized at a relatively low temperature of 800℃. The reducibility of La0.6Sr0.4Co0.8Fe0.2O3-δ was also characterized by the temperature programmed reduction （TPR） technique. Disk shaped dense La0.6Sr0.4Co0.8Fe0.2O3-δ membrane was prepared by the isostatical pressing method. The oxygen flux rate of dense La0.6Sr0.4Co0.8Fe0.2O3-δ membrane was （2.8-18）× 10^-8 mol/（cm^2.s） in the temperature range of 800-1000 ℃.

关键词： perovskite La0.6Sr0.4Co0.8Fe0.2O3-δ oxygen permeation preparation characterization

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艾灸治疗排卵障碍性疾病的作用机制研究概述

环球中医药 2024年第3期17卷 551-557页

作者：付雅琪魏伟峰胡小芳河南中医药大学第一临床医学院郑州450000 河南中医药大学第一附属医院普罗门诊

排卵障碍包括稀发排卵及无排卵,是生殖医学科的常见病种。中医认为本病根本责之肾虚,治疗以补肾为主。笔者查阅相关资料,发现艾灸对本病的治疗有其独特疗效,其起效机制包含以下五个方面:(1)调节生殖激素、甲状腺激素、肾上腺皮质激素水... 详细信息

排卵障碍包括稀发排卵及无排卵,是生殖医学科的常见病种。中医认为本病根本责之肾虚,治疗以补肾为主。笔者查阅相关资料,发现艾灸对本病的治疗有其独特疗效,其起效机制包含以下五个方面:(1)调节生殖激素、甲状腺激素、肾上腺皮质激素水平,改善内分泌紊乱;(2)调控氧化应激及颗粒细胞凋亡,改善因卵巢功能衰退导致的排卵障碍;(3)调节卵泡液中细胞因子的表达,促进颗粒细胞的分裂及卵母细胞的发育成熟;(4)改善卵巢血液微循环,缓解卵泡缺氧;(5)改善卵巢组织形态,恢复卵巢排卵功能。本文从艾灸治疗排卵障碍性疾病的实验研究与临床研究两方面出发,总结近年来艾灸治疗本病的作用机制的一手文献,并分析目前研究优势及不足点,以期为未来临床应用提供理论基础和应用思路。

关键词：艾灸排卵障碍下丘脑-垂体-卵巢轴甲状腺激素氧化应激颗粒细胞凋亡炎症因子卵巢动脉血流

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Analog memristive memory with applications in audio signal processing

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Science China(Information Sciences) 2014年第4期57卷 243-257页

作者： DUAN ShuKai hu xiaofang WANG LiDan LI ChuanDong School of Electronics and Information Engineering Southwest University Department of Mechanical and Biomedical Engineering City University of Hong Kong

Since the development of the HP memristor,much attention has been paid to studies of memristive devices and applications,particularly memristor-based nonvolatile semiconductor *** to its unique properties,theoretically,one could restart a memristor-based computer immediately without the need for reloading the ***,current memories are mainly binary and can store only ones and zeros,whereas memristors have multilevel states,which means a single memristor unit can replace many binary transistors and realize higher-density *** is believed that memristors can also implement analog storage besides binary and multilevel information *** this paper,an implementation scheme for analog memristive memory is considered.A charge-controlled memristor model is derived and the corresponding SPICE model is *** write and read operations are demonstrated through numerical analysis and circuit *** addition,an audio analog record/play system using a memristor crossbar array is *** system can provide great storage capacity(long recording time)and high audio quality with a simple small circuit structure.A series of computer simulations and analyses verify the effectiveness of the proposed scheme.

关键词： memristor analog memory circuit simulation record/play system audio signal storage

Fixed-time stabilization of discontinuous spatiotemporal neural networks with time-varying coefficients via aperiodically switching control

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Science China(Information Sciences) 2023年第5期66卷 182-195页

作者： xiaofang hu Leimin WANG Chuan-Ke ZHANG Xiongbo WAN Yong HE School of Automation China University of Geosciences hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex Systems Engineering Research Center of Intelligent Technology for Geo-Exploration Ministry of Education

This paper focuses on the challenge of fixed-time control for spatiotemporal neural networks(SNNs) with discontinuous activations and time-varying coefficients. A novel fixed-time convergence lemma is proposed, which facilitates the handling of time-varying coefficients of SNNs and relaxes the restriction on the non-positive definiteness of the derivative of the Lyapunov function. Besides, a more flexible and economical aperiodically switching control technique is presented to stabilize SNNs within a fixed time,efectively reducing the amount of information transmission and control costs. Under the newly established fixed-time convergence lemma and aperiodically switching controller, many more general algebraic conditions are deduced to ensure the fixed-time stabilization of SNNs. Numerical examples are provided to manifest the validity of the results.

关键词： spatiotemporal neural networks discontinuous activations time-varying coefficients fixed-time stabilization aperiodically switching control