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World Journal of Gastroenterology 2009年第7期15卷 860-864页

作者： Hong Cheng Fu-lian hu Department of Gastroenterology Peking University First Hospital Beijing 100034 China

AIM： To compare the efficacy and side effect profiles of three furazolidone and amoxicillin-based quadruple rescue therapies for the eradication of Helicobacter pylori （H pylonS. METHODS： Patients who failed in the Hpylori eradication therapy for at least one course were randomly allocated into three groups. Group A received rebaprazole 10 mg＋ amoxicillin 1 g ＋ furazolidone 100 mg, and bismuth subcitrate 220 mg, twice daily for 1 wk; group B received the same regimen of group A but for 2 wk; and group C received the same regimen of group B, but furazolidone was replaced by furazolidone 100 mg three times daily. To record the side effect profiles at the end of the treatment, Hpylori eradication was assessed with 13C-urea breath test 4 wk after therapy. RESULTS： Sixty patients were enrolled including 28 males, and 20 patients in each group. The average age of the patients was 49.2 years, ranging from 18 to 84 years. H pylori eradication rates with per-protocol analysis were 82%, 89% and 90% in the three groups, respectively. Side effects were found in 11 patients, including mild dizziness, nausea, diarrhea and increased bowel movement. None of the 11 patients needed treatment for their side effects. CONCLUSION： One- or two-week furazolidone and amoxicillin-based quadruple rescue therapy with a low dose furazolidone （100 mg bid） for the eradication of Hpylori is effective. Extending the antibiotic course to 14 d could improve the eradication rates.

关键词： Helicobacter pylori Rescue therapy Quadruple therapy Furazolidone Low dose

Effect of Seasonality on Distribution of Macroalgae in a Stream System(Xin'an Spring) in Shanxi Province,North China

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Journal of Integrative Plant Biology 2006年第8期48卷 889-896页

作者： Bian-Fang hu Shu-lian Xie School of Life Science and Technology Shanxi University Taiyuan 030006 China

A survey of the seasonal distribution of macroalgae in a stream system in Shanxi Province, north China, was undertaken from July 2004 to April 2005. The relative abundance and percentage cover of macroalgae, and several environmental factors were monitored along a 20-m stretch at each of four sites, at intervals of approximately three months （one sampling per season）. Several stream conditions were relatively constant over the sampling period （pH, maximum width and maximum depth）, whereas others exhibited a distinct seasonal pattern （water temperature and specific conductance）, and some fluctuated with no discernable seasonal pattern （current velocity and dissolved oxygen）. Forty-two species of macroalgae were found, with a predominance of Chlorophyta （26 species, 61.9%）. Rhodophyts and Charophyta represented the smallest proportion （1 species each, 2.38%）. Six macroalgae species were the most widespread, occurring in all four sampling sites. Twelve species were found at only one site each. In terms of seasonality, eight species occurred throughout the year, whereas 16 species were found in only one season each. The macroalgal community at Xin＇an Spring was species rich relative to other streams. Species richness per sampling site was negatively correlated with pH. Principal component analysis revealed that no single variable had much influence on the macroalgal seasonal dynamics. We calculated Sorensen similarity indices to compare our study with other continent-wide surveys of stream macroalgae, but the similarity indices were all very low. This study also shows that macroalgae in different locations have significant reproductive isolation.

关键词： China distribution environmental factors seasonality stream macroalgae.

Distribution of gyrA mutations in fluoroquinolone-resistant Helicobacter pylori strains

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World Journal of Gastroenterology 2010年第18期16卷 2272-2277页

作者： Wang, Li-hui Cheng, Hong hu, Fu-lian Li, Jiang Peking Univ First Hosp Dept Gastroenterol Beijing 100034 Peoples R China

AIM:To investigate the resistance of Helicobacter pylori(***) to ciprofloxacin(CIP),levofloxacin(LVX) and moxifloxacin(MOX) in the Beijing area and to elucidate the resistance ***:Seventy-nine *** clinical strains,isolated from patients who had undergone upper gastrointestinal endoscopy in Peking University First Hospital from 2007 to 2009,were tested for their susceptibility to CIP,LVX and MOX using the E-test *** strain 26695 was included in the susceptibility testing as a control *** to the minimal inhibitory concentration(MIC) values,a strain was classified as resistant to CIP,LVX or MOX when the MIC was > 1 μg/*** amplified by polymerase chain reaction(PCR) and sequenced the quinolone resistance-determining regions of the gyrA and gyrB genes from 29 quinolone-resistant and 16 quinolone-susceptible *** strains selected at ***:In this study,the resistance rates of *** to CIP,LVX or MOX were 55.7%(44/79),and the primary resistance rates were 26.6%(21/79).Patients with secondary resistance had received LVX in previous eradication treatments,but not MOX or ***-five strains,including 29 CIP,LVX or MOX-resistant strains(MIC:1.5-32 μg/mL) and 16 susceptible strains,were selected randomly from the 79 strains and used in PCR *** these 45 strains,27 resistant strains had mutations in the gyrA gene,including 11 strains with mutations corresponding to Asp-91(MIC:2-32 μg/mL),one of which also had a mutation corresponding to Val-150,and 16 strains had mutations at Asn-87(MIC:4-32 μg/mL),three of which also had mutations corresponding to Arg-140 or *** addition,Arg-140,Val-150 or Ala-97 mutations were separately detected in three susceptible *** of the gyrB gene showed that one strain of low resistance had a mutation corresponding to Ser-457 that coexisted with an Asp-91 *** was a significant difference in the occurrence of mutations in the gyrA gene between

关键词： Helicobacter pylori Antibiotic resistance Quinolones Mutation gyrA

Influence of Strong Electron-Electron Interaction on the Peierls Transition

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Chinese Physics Letters 1997年第1期14卷 63-66页

作者： hu lian K.Y.Szeto SUN Xin Department of Physics South China Normal UniversityGuangzhou 510631 Department of Physics The Hong Kong University of Science and TechnologyHong Kong Department of Physics Fudan UniversityShanghai 200433

The influence of short-ranged Coulomb repulsion of strongly correlated electrons on the Peierls transition for a quasi-one-dimensional system is *** shows that the influence varies with the band filling and proves that the condition of single-occupation leads to a singularity on the density of states at half-filling which enhances *** also shows that dimerization is suppressed by the increase of U in the region of large-U and proves that increasing nearest-neighbor interaction V will suppress the Peierls transition temperature at half-filling,and strongly enhance it for band-filling at n≈1/4,which means the enhancement of tetramer-ization for a quarter-filled band.

关键词： Electron Peierls singularity

Meropenem as an Alternative Antibiotic Agent for Suppression of Agrobacterium in Genetic Transformation of Orchid

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Agricultural Sciences in China 2006年第11期5卷 839-846页

作者： CAO Ying Niimi Yoshiyuki hu Shang-lian School of Life Science and Engineering Southwest University of Science and Technology Mianyang 621000 P.R. China Department of Plant Resources Hiroshima Prefectural University Hiroshima 727-0027 Japan

A case of Meropenem as a novel antibacterial agent to suppress and eliminate Agrobacterium tumefaciens in the Agrobacterium-mediated transformation of orchid protocorm-like bodies （PLBs） has been reported in this article. The in vitro activities of meropenem and four comparator antibacterial agents against three Agrobacterium tumefaciens strains, LBA4404, EHA101, and GV3101, were assessed. In addition, the effect of meropenem on the growth of Dendrobium phalaenopsis PLBs was determined. Compared with other commonly used antibiotics （including ampicillin, carbenicillin, cefotaxime, and cefoperazone）, meropenem showed the highest activity in suppressing all tested A. tumefaciens strains （minimum inhibitory concentration [MIC] 〈 0.5 mg L^-1, which is equal to minimum bactericidal concentration [MBC]）. Meropenem, at all tested concentrations, except for 10 mg L^-1 concentration, had little negative effect on the growth of orchid tissues. The A. tumefaciens strain EHA101 in genetic transformation with vector plG121Hm in infected PLBs of the orchid was visually undetectable after a two-month subculture in 1/2 MS medium with 50 mg L^-1 meropenem and 25 mg L^-1 hygromacin. The expression and incorporation of the transgenes were confirmed by GUS histochemical assay and PCR analysis. Meropenem may be an alternative antibiotic for the effective suppression of A. tumefaciens in genetic transformation.

关键词： antibiotics meropenem Agrobacterium tumefaciens antibacterial activity genetic transformation protocormlike bodies (PLBs)

Thermoelectric properties of Al substituted misfit cobaltite Ca_3(Co_(1-x)Al_x)_4O_9 at low temperature

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International Journal of Minerals,Metallurgy and Materials 2014年第7期21卷 720-725页

作者： Yi Liu Hong-mei Chen Jin-lian hu Xu-bing Tang Hai-jin Li Wei Wang School of Mathematics and Physics Anhui University of Technology Institute of Optoelectronic Information Materials and Technologies Anhui University of Technology School of Materials Science & Engineering Anhui University of Technology

Thermoelectric properties of Al substituted compounds Ca3（Co1-xAlx）4O9 （x=0, 0.03, 0.05）, prepared by a sol-gel process, have been investigated in the temperature range 305-20 K. The results indicate that after Al substitution for Co in Ca3（Co1-xAlx）4O9, the direct current electrical resistivity and thermopower increase due to the reduction of carrier concentration. Experiments show that Al substitution results in decreased lattice thermal conductivity. The figure of merit of temperature behavior suggests that Ca3（Co0.97Al0.03）4O9 would be a promising candidate thermoelectric material for high-temperature thermoelectric application.

关键词： transition metal oxides sol-gel process thermoelectricity electrical properties substitution

Use of the N-alkanes to Estimate Intake, Apparent Digestibility and Diet Composition in Sheep Grazing on Stipa brevifl ora Desert Steppe

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Journal of Integrative Agriculture 2014年第5期13卷 1065-1072页

作者： hu Hong-lian LIU Yong-zhi LI Ya-kui LU De-xun GAO Min Institute of Animal Nutrition and Feed Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences Inner Mongolia Prataculture Research Center Chinese Academy of Sciences Institute of Botany Chinese Academy of Sciences College of Animal and Technology Hebei North University

The application of n-alkane as markers to estimate herbage intake, apparent digestibility and species composition of diet consumed by grazing sheep was studied. Six local Mongolian sheep were used to determine dry matter （DM） intake, apparent DM digestibility and species composition of diet during summer, autumn and winter. Animals were orally dosed twice daily with n-alkane gelatin capsules containing 60 mg C32-alkane as an external marker. Diet composition was estimated by comparing the odd-chain n-alkanes pattern profile （C27-C31） of the consumed plant species with the n-alkanes fecal concentrations of grazing animals, using a non-negative least squares algorithm called EATWHAT software package. The alkane pair C32：C33 and C33 alkane were used to estimate DM intake and diet apparent DM digestibility, respectively. The results showed that daily dry matter intake of the sheep were 1.77, 1.61 and 1.18 kg d-1 in summer, autumn and winter, respectively. Apparent DM digestibility, crude protein （CP）, metabolizable energy （ME） and neutral detergent fiber （NDF） intake of diet consumed by sheep decreased significantly （P〈0.01） from summer to winter, with no evident changes in ADF and ADL intake. Diet composition indicated Artemisia frigida Willd was the most dominant diet component, contributed 79.68, 68.12 and 86.26% of sheep＇s diets in summer, autumn and winter, respectively. Cleistogenes songorica Ohwi and Convolvulus arnmannii Desr were the important components of the diet. Although Stipa breviflora Griseb is one of the main plant species in the study area, the sheep rarely choosed it. The study indicated that CP and ME in diet consumed by sheep were deficient in winter. Therefore, appropriate supplementation strategies should be indispensable during this period.

关键词： n-alkanes diet composition intake apparent digestibility sheep

Analysis of the track system in bumpy unstructured hard road environment by vibration test

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International Journal of Agricultural and Biological Engineering 2022年第4期15卷 163-171页

作者： Mutong Li Junlue Li Lin He Jie He lian hu Chengxu Lyu Key Laboratory of Modern Agricultural Intelligent Equipment in South China Ministry of Agriculture and Rural AffairsChina/Guangdong Institute of Modern Agricultural EquipmentGuangzhou 510630China College of Engineering South China Agricultural UniversityGuangzhou 510642China Chinese Academy of Agricultural Mechanization Sciences Beijing 100083China

The complex terrain environment in the hilly land directly affects the operational reliability of agricultural *** order to study the impact of road irregularity on walking chassis vibration,the 3CYLZ-750 remote-controlled weeding machine which is applied to orchards was taken as the object of study,and the rear roller was selected as the object of observation to reveal the rules under which the vibration of the track chassis changes as there is a sudden change in road surface elevation.A column-type test-to-pass method based on unit excitation was proposed in this *** excitation behavior and action process were analyzed by category.A critical acceleration prediction model was built and verified by virtual simulation and hard road surface excitation *** results showed that at the forward velocity of 0-2.5 km/h and exciter height of 20-100 mm,the vertical vibration acceleration of the target roller was significantly affected by Track Contact Point Centrifugal Acceleration(TCPCA).As TCPCA increased,the change rate of vertical vibration acceleration decreased,reaching a minimum of[−13.8,28.8];as TCPCA decreased,the vertical vibration acceleration tended to increase positively at a maximum variation range of[−13.3,42.2].The measured and simulated macroscopic change rules were consistent with the theoretical analysis,further verifying the correctness of variable extraction,and providing a research basis for the accurate modification and improvement of the *** research conclusions can lay a theoretical foundation for analyzing the walking reliability of the track chassis,and provide a design basis and technical support for the development of a tracked agricultural robot chassis for the hilly land in the future.

关键词： track system unstructured road vibration test simulation analysis hilly land agricultural robot

Large-scale synthesis of nickel sulfide micro/nanorods via a hydrothermal process

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International Journal of Minerals,Metallurgy and Materials 2015年第7期22卷 762-769页

作者： Peng-fei Yin Xiang-yu Han Chao Zhou Chuan-hui Xia Chun-lian hu Li-li Sun College of Science Chongqing Jiaotong University Department of Materials Science Chongqing Jiaotong University Department of Physics Third Military Medical University

Rhombohedral-phase NiS micro/nanorods were synthesized on a large scale through a hydrothermal method using NiCl2·6H2O and thiourea crystals as starting precursors. Recrystallized thiourea was observed to play an important role in the formation of mi- cro/nanosized rods and flower-like structures. The molar ratio and reaction temperature of the precursors influenced the morphology and phase of NiS products. Pure rhombohedral NiS micro/nanorods were obtained on a large scale when the molar ratio between NiCl2·6H2O and thiourea crystals was fixed at 2：1, and the mixture was heated at 250℃ for 5 h. Flower-like NiS nanostructures were formed when the molar ratio between NiCl2·6H2O and thiourea crystals was maintained at 1：1. The Raman and Fourier-transform infrared （FTIR） spectra of the as-prepared rhombohedral NiS micro/nanorods were collected, and their magnetic properties were investigated. The results showed that the FTIR absorption peaks of the as-prepared product are located at 634 cm^-1 and their Raman peaks are located at 216 and 289 cm^-1; the as-prepared NiS micro/nanorods exhibited weak ferromagnetic behavior due to the size effect.

关键词： nickel sulfide nanorods hydrothermal synthesis optical properties magnetic measurement

Grain refining and property improvement of AZ31 Mg alloy by hot rolling

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Transactions of Nonferrous Metals Society of China 2009年第S02期19卷 326-330页

作者： MIAO Qing hu lian-xi SUN Hong-fei WANG Er-de School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China

Hot rolling of AZ31 Mg alloy was performed by using as-cast alloy ingot as the starting *** microstructures and mechanical properties of the as-rolled alloy subjected to various rolling passes were *** results show that the grain size of the alloy can be refined steadily with increasing rolling passes by dynamic *** the steady refining of the grain size,both the mechanical strength and the plasticity of the alloy are improved *** particular,when the grain size is reduced to about 5μm after 5 rolling passes,the yield strength,ultimate tensile strength and tensile fracture strain of the alloy are 211 MPa,280 MPa and 0.28 in the transverse direction,they are 200 MPa,268 MPa and 0.32 in the rolling direction,respectively.

关键词： AZ31 Mg alloy hot rolling grain refining mechanical properties