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FCSR PERIODIC MULTISEQUENCES WITH MAXIMAL JOINT N-ADIC COMPLEXITY AND LARGE k-ERROR JOINT N-ADIC COMPLEXITY OVER Z/(N)

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Journal of Systems Science & Complexity 2014年第2期27卷 370-381页

作者： LI Fulin hu honggang Zhu Shixin Department of Applied Mathematics Hefei University of Technology School of Information Science and Technology University of Science and Technology of China

Complexity measures for keystream multisequences over Z/(N) play a crucial role in designing good stream cipher systems. This correspondence shows a general upper bound on k-error joint N-adic complexity of periodic multisequences over Z/(N), and establishes the existence of periodic N-adic multisequences over Z/(N) which simultaneously possess maximal joint N-adic complexity and large k-error joint N-adic complexity. Under some conditions the overwhelming majority of all T-periodic N-adic multisequences over Z/(N) with maximal joint N-adic complexity logN(NT- 1)have a k-error joint N-adic complexity close to logN(NT- 1).

关键词： Cryptography N-adic numbers joint N-adie complexity k-error joint N-adic complexity stream cipher.

Generalized cryptanalysis of RSA with small public exponent

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Science China(Information Sciences) 2016年第3期59卷 97-106页

作者： Mengce ZHENG honggang hu Zilong WANG Key Laboratory of Electromagnetic Space Information Chinese Academy of Sciences (CAS) School of Information Science and Technology University of Science and Technology of China

In this paper, we demonstrate that there exist weak keys in the RSA public-key cryptosystem with the public exponent e = NαN0.5. In 1999, Boneh and Durfee showed that when α≈ 1 and the private exponent d = Nβ< N0.292, the system is insecure. Moreover, their attack is still effective for 0.5 < α < *** propose a generalized cryptanalytic method to attack the RSA cryptosystem with α≤0.5. For c = [（1-α）/α] and eγc≡ d（mod ec）, when γ, β satisfy γ < 1+1/c-1/（2αc） and β < αc +7/6- αγc-1/3（6α + 6αc + 1- 6αγc）1/2, we can perform cryptanalytic attacks based on the LLL algorithm. The basic idea is an application of Coppersmith's techniques and we further adapt the technique of unravelled linearization, which leads to an optimized *** advantage is that we achieve new attacks on RSA with α 0.5 and consequently, there exist weak keys in RSA for most α.

关键词： cryptanalysis RSA LLL algorithm Coppersmith’s techniques unravelled linearization

Efficient Pairing Computation on Twisted Weierstrass Curves

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Chinese Journal of Electronics 2018年第4期27卷 739-745页

作者： WANG Bei OUYANG Yi hu honggang School of Mathematical Sciences University of Science and Technology of China School of Information Science and Technology University of Science and Technology of China

In this paper, we construct the twists of twisted Edwards curves in Weierstrass form. Then we define a new twisted Ate pairing on twisted Weierstrass curves named the Tx-Ate pairing. Following Miller’s algorithm, we give a computation of the Tx-Ate pairing on high degree twisted Weierstrass curves, where the point operations are over Edwards form, and the computation of Miller function is over Weierstrass form. Although, in one doubling loop, our method to compute the Tx-Ate pairing is a litter slower than the previously fastest *** twists, the Tx-Ate pairing can be calculated on more twisted Weierstrass curves with short loop length. The TxAte pairing is even competitive with optimal Ate pairing when they have the same short loop length.

关键词： Weierstrass curves Twisted Ate pairing Twisted Edwards curves Miller function

Efficient beyond-birthday-bound secure authenticated encryption modes

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Science China(Information Sciences) 2018年第9期61卷 285-296页

作者： Ping ZHANG honggang hu Peng WANG School of Information Science and Technology University of Science and Technology of China Key Laboratory of Electromagnetic Space Information Chinese Academy of Sciences Institute of Information Engineering Chinese Academy of Sciences

The privacy and authenticity of user information have received increasing attention,because information security incidents have occurred more frequently in recent years,such as the PRISM scandal and blackmail *** this... 详细信息

关键词： IV Efficient beyond-birthday-bound secure authenticated encryption modes FK

Tryptophan-specific peptide modification through metal-free photoinduced N-H alkylation employing N-aryl glycines

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Chinese Chemical Letters 2024年第6期35卷 316-319页

作者： Jianhui Yin Wenjing huang Changyong Guo Chao Liu Fei Gao honggang hu School of Medicine or Institute of Translation Medicine Shanghai UniversityShanghai 200444China

Tryptophan(Trp)carries a unique heteroaromatic indole side chain and plays a critical role in peptide or protein ***,we have reported a metal-free photoinduced N-H alkylation strategy using N-aryl glycines for specific modification of tryptophan-containing *** robustness of our approach is demonstrated by its wide substrate scope,excellent isolated yields,as well as almost unobservable side *** this highly efficiently metal-free condition,alkylated Trp-containing peptides can be smoothly *** study provides a reliable and practical tool for the chemo-selective modification of various tryptophan containing oligopeptides.

关键词： Tryptophan Peptide Modification Glycine Photoinduced

Total synthesis of TRADD death domain with arginine N-GlcNAcylation by hydrazide-based native chemical ligation

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Chinese Chemical Letters 2020年第1期31卷 107-110页

作者： Ye Wu Yulei Li Wei Cong Yan Zou Xiang Li honggang hu Institute of Translational Medicine Shanghai UniversityShanghai 200436China School of Pharmacy Second Military Medical UniversityShanghai 200433China Key Laboratory of Marine Drugs Ministry of EducationSchool of Medicine and PharmacyOcean University of ChinaQingdao 266003China

TNFR1-associated death domain protein(TRADD)with arginine N-GlcNAcylation is a novel and structurally unique posttranslational modification(PTM)glycoprotein that blocks the formation of death-inducing signaling complex(DISC),orchestrating host nuclear factorκB(NF-κB)signaling in entero-pathogenic Escherichia coli(EPEC)-infected *** particular glycosylated modification plays an extremely vital role for the effective colonization and pathogenesis of pathogens in the *** we describe the total synthesis of TRADD death domain(residues 195-312)with arginine235 NGlcNAcylation(Arg-GIcNAc TRADD(195-312)).Two longish peptidyl fragments of the wild-type primary sequence were obtained by robust,microwave-assisted,highly efficient,solid-phase peptide synthesis(SPPS),the N-GlcNAcylated sector was built by total synthesis and attached specifically to resinbound peptide with an unprotected ornithine residue via silver-promoted on-resin guanidinylation,ArgGlcNAc TRADD(195-312)was constructed by hydrazide-based native chemical ligation(NCL).The facile synthetic strategy is expected to be generally applicable for the rapid synthesis of other proteins with Arg-GIcNAc modification and to pave the way for the related chemically biological study.

关键词： TRADD death domain Posttranslational modification Protein chemical synthesis Solid-phase peptide synthesis Native chemical ligation Peptide hydrazide

Multi-user security of the tweakable Even-Mansour cipher

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Science China(Information Sciences) 2021年第5期64卷 223-225页

作者： Ping ZHANG Qian YUAN honggang hu Peng WANG School of Computer Science Nanjing University of Posts and Telecommunications School of Economics and Management Southeast University School of Information Science and Technology University of Science and Technology of China Institute of Information Engineering Chinese Academy of Sciences

Dear editor,Data security, including data privacy security and data integrity security, are usually achieved by a cryptographic algorithm. Block ciphers are widely used to design the cryptographic scheme. However, in some special environments, block ciphers are no longer applicable. A tweakable blockcipher(TBC) is an improved version of a conventional block cipher, which adds an extra input, called tweak,

关键词： Information Systems and Communication Service

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Peptide stapling with the retention of double native side-chains

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Chinese Chemical Letters 2021年第12期32卷 4045-4048页

作者： Ye Wu Yan Zou Lingling Sun Alfredo Garzino-Demo honggang hu Weidong Zhang Xiang Li Institute of Interdisciplinary Integrative Medicine Research Shanghai University of Traditional Chinese MedicineShanghai 201203China School of Pharmacy Second Military Medical UniversityShanghai 200433China Institute of human Virology and Department of Microbiology and Immunology University of Maryland School of MedicineBaltimore MD 21201United States Department of Molecular Medicine University of PadovaPadova 35121Italy Institute of Translational Medicine Shanghai UniversityShanghai 200444China

All-hydrocarbon stapling strategy has been widely applied for enhancing the proteolytic stability of peptides. However, two major technical hurdles to some extent limit the development of stapled peptides for therapeutic usage: rational selection of the stapling sites and the corresponding deletion of the native side chains. Previously we described the development of the olefin-terminated amino acids with the retention of native side chains and successfully applied them in the synthesis of hydrocarbon stapled peptides with single side-chain retention. Here, we explored the feasibility and effectiveness of hydrocarbon stapling strategy characterized as double side-chains retention. Modeled after a lengthy human immunodeficiency virus-1(HIV-1) fusion inhibitor SC34 EK, Leu^(i), Ser^(i+4)and Lys^(i), Leu^(i+4)stapled peptides with the retention of double side-chains were effectively obtained. Our complementary study provided a convenient alternative to address where to install the staple in sequence for conventional all-hydrocarbon peptide stapling. Furthermore, this method not only conferred conformational reinforcement for SC34 EK with high α-helicity and protease resistance, but also preserved the structural characteristic(key peripheral residues, charge and solubility) of the linear peptide to the maximum, which are crucial for anti-HIV-1 activity.

关键词： Stapling strategy Stapled peptide Native side chain Peptide drug design HIV-1 fusion inhibitor SC34EK

Development, chromosome location and genetic mapping of EST-SSR markers in wheat

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Chinese Science Bulletin 2005年第20期50卷 2328-2336页

作者： CHEN Haimei LI Linzhi WEI Xianyun LI Sishen LEI Tiandong hu Haizhou WANG honggang ZHANG Xiansheng College of Agronomy Shandong Agricultural University/Shandong KeyLab of Crop Biology Tai'an 271018 China

A number of 151695 wheat expression sequence tags (ESTs) that originated from GenBank/dbEST from July 14, 2003 to August 24, 2004 were used to search for simple sequence repeats (SSRs) with motif 2―5 bp, and 2038 simple sequence repeats (EST-SSRs), which accounted for 1.34% of EST database, were identified. Based on these SSR sequences, 249 EST-SSR primer pairs and 166 amplified clear bands in various wheat cultivars were designed. These EST-SSR markers can be used as new molecular markers in wheat and related species. Using Chinese Spring nulli-tetrasomic lines, 93 EST-SSR primer pairs and 193 EST-SSR loci were located on 19 wheat chromosomes except for 4A and 4B. Forty-three loci were mapped on 11 chromosomes of the genetic frame- work map previously constructed using recombinant inbred lines.

关键词：染色体遗传映射小麦序列重复 EST