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Enterococcus faecalis provides protection during scavenging in carrion crow (Corvus corone)

Zoological Research 2024年第3期45卷 451-463页

作者： bin hu Jia-Min Wang Qing-Xun Zhang Jing Xu Ya-Nan Xing Bo Wang Shu-Yi Han Hong-Xuan He CAS Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China College of Life Sciences University of Chinese Academy of SciencesBeijing 100049China Beijing Milu Ecological Research Center Beijing 102600China Beijing Capital International Airport Co. Ltd.Beijing 101300China

The gut microbiota significantly influences host physiology and provides essential ecosystem *** diet can affect the composition of the gut microbiota,the gut microbiota can also help the host adapt to specific dietary *** carrion crow(Corvus corone),an urban facultative scavenger bird,hosts an abundance of pathogens due to its scavenging *** this,carrion crows infrequently exhibit illness,a phenomenon related to their unique physiological *** present,however,the role of the gut microbiota remains incompletely *** this study,we performed a comparative analysis using 16S rRNA amplicon sequencing technology to assess colonic content in carrion crows and 16 other bird species with different diets in Beijing,*** findings revealed that the dominant gut microbiota in carrion crows was primarily composed of Proteobacteria(75.51%)and Firmicutes(22.37%).Significant differences were observed in the relative abundance of Enterococcus faecalis among groups,highlighting its potential as a biomarker of facultative scavenging behavior in carrion ***,*** isolated from carrion crows was transplanted into model mice to explore the protective effects of this bacterial community against Salmonella enterica *** showed that *** down-regulated the expression of pro-inflammatory cytokines tumor necrosis factor alpha(TNF-α),interferon gamma(IFN-γ),and interleukin 6(IL-6),prevented *** colonization,and regulated the composition of gut microbiota in mice,thereby modulating the host’s immune regulatory ***,*** exerts immunoregulatory and anti-pathogenic functions in carrion crows engaged in scavenging behavior,offering a representative case of how the gut microbiota contributes to the protection of hosts with specialized diets.

关键词： Carrion crow Facultative scavenger Gut microbiota Enterococcus faecalis 16S rRNA sequencing

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Differences and Correlations of Morphological and Hemodynamic Parameters between Anterior Circulation Bifurcation and Side-wall Aneurysms

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Current Medical Science 2024年第2期44卷 391-398页

作者： Kai-kai GUO Chang-ya LIU Gao-hui LI Jian-ping XIANG Xiao-chang LENG Yi-ke CAI Xue-bin hu Department of Neurosurgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Emergency Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai 200032China Artery Flow Technology Co. Ltd.Hangzhou 310051China

Objective:The objective of this research was to explore the difference and correlation of the morphological and hemodynamic features between sidewall and bifurcation aneurysms in anterior circulation arteries,utilizing computational fluid dynamics as a tool for ***:In line with the designated inclusion criteria,this study covered 160 aneurysms identified in 131 patients who received treatment at Union Hospital of Tongji Medical College,huazhong University of Science and Technology,China,from January 2021 to September *** follow-up digital subtraction angiography(DSA)data,these cases were classified into two distinct groups:the sidewall aneurysm group and the bifurcation aneurysm *** and hemodynamic parameters in the immediate preoperative period were meticulously calculated and examined in both groups using a three-dimensional DSA reconstruction ***:No significant differences were found in the morphological or hemodynamic parameters of bifurcation aneurysms at varied locations within the anterior ***,pronounced differences were identified between sidewall and bifurcation aneurysms in terms of morphological parameters such as the diameter of the parent vessel(Dvessel),inflow angle(θF),and size ratio(SR),as well as the hemodynamic parameter of inflow concentration index(ICI)(P0.5,P<0.001).Conclusions:The significant differences in certain morphological and hemodynamic parameters between sidewall and bifurcation aneurysms emphasize the importance to contemplate variances in threshold values for these parameters when evaluating the risk of rupture in anterior circulation *** it is a bifurcation or sidewall aneurysm,these disparities should be *** morphological parameter SR has the potential to be a val

关键词： sidewall bifurcation unruptured aneurysms computational fluid dynamics

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Recent progress of hybrid cathode interface layer for organic solar cells

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Journal of Energy Chemistry 2024年第4期91卷 383-406页

作者： Jianru Wang Dan Zhou Zhentian Xu Yujie Pu Senmei Lan Fang Wang Feiyan Wu bin hu Yongfen Tong Ruizhi Lv Honglin Chu Lie Chen Key Laboratory of Jiangxi Province for Persistent Pollutants Control and Resources RecycleNanchang Hangkong UniversityNanchang 330063JiangxiChina College of Chemistry and Chemical Engineering/Institute of Polymers and Energy Chemistry(IPEC) Nanchang UniversityNanchang 330031JiangxiChina

Organic solar cells(OSCs)have gained conspicuous progress during the past few decades due to the development of materials and upgrading of the device *** power conversion efficiency(PCE)of the single-junction device had surpassed 19%.The cathode interface layer(CIL),by optimizing the connection between the active layer and the cathode electrode,has become a momentous part to strengthen the performances of the ***,CIL is also indispensable to illustrating the working mechanism of OSCs and enhancing the stability of the *** this essay,hybrid CILs in OSCs have been ***,the advancement and operating mechanism of OSCs,and the effects and relevant design rules of CIL are briefly concluded;secondly,the significant influence of CIL on enhancing the stability and PCE of OSCs is presented;thirdly,the characteristics of organic hybrid CIL and organic-inorganic hybrid CIL are ***,the conclusion and outlook of CIL are summarized.

关键词： Organic solar cells Theoperation mechanism Organic hybrid cathode interface layer Organic-inorganic hybrid CIL

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Intracellular redox potential-driven live-cell synthesis of CdSe quantum dots in Staphylococcus aureus

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Science China Chemistry 2024年第3期67卷 990-999页

作者： Cai-Qin Wu An-An Liu Xu Li Jia-Wei Tu Juan Kong Ling-Ling Yang Jian-Hong Jia Chuan Wang bin hu Zhi-Xiong Xie Dai-Wen Pang The Institute for Advanced Studies College of Chemistry and Molecular SciencesCollege of Life SciencesHubei Key Laboratory of Cell HomeostasisWuhan UniversityWuhan 430072China Research Center for Analytical Sciences College of ChemistryState Key Laboratory of Medicinal Chemical BiologyTianjin Key Laboratory of Biosensing and Molecular RecognitionFrontiers Science Center for New Organic MatterFrontiers Science Center for Cell Responsesand Haihe Laboratory of Sustainable Chemical TransformationsNankai UniversityTianjin 300071China

Biosynthesized semiconductor quantum dots(QDs) have bright fluorescence,adjustable particle sizes,and environmental friendliness,endowing them with convenience and potential for biological *** to the unclear mechanism of the cellular environment on the live-cell synthesis of QDs,it is still difficult to regulate their optical ***,the critical role of the intracellular redox environment in regulating the fluorescence properties of biosynthesized CdSe QDs in Staphylococcus aureus(***) has been *** glutathione peroxidase(GPx) activity directly affects the intracellular H_(2)O_(2) produced in the SeO_(3)^(2-) reduction,which further manipulates the glutathione redox cycle to determine the content of low-valence *** a result,the fluorescence intensity of the synthesized CdSe QDs increases by 60% in the GPx overexpressed *** cellular redox potential that is controlled by the GSH redox cycle provides the driving force for the reduction of SeO_(3)^(2-),facilitating the synthesis of CdSe QDs in *** *** proposed mechanism of the cellular redox state provides a new perspective for regulating the synthesis of semiconductor nanomaterials in live cells.

关键词： redox H_(2)O_(2) peroxidase quantum dot Staphylococcus aureus

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框架中的关系关系中的框架——地形与栖居的关联性研究

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建筑学报 2024年第1期 81-87页

作者：胡滨同济大学建筑与城市规划学院上海200092

从地形可提供人栖居的框架—“场域和景致”出发,探讨如何构建地形与栖居的关联。在探讨框架的内容和特征基础上,以设计可操作的要素确立地形介入栖居的方式和构建两者关系的方法:唤醒记忆、触摸场地、重塑地景、显现大地和框取景致,并... 详细信息

从地形可提供人栖居的框架—“场域和景致”出发,探讨如何构建地形与栖居的关联。在探讨框架的内容和特征基础上,以设计可操作的要素确立地形介入栖居的方式和构建两者关系的方法:唤醒记忆、触摸场地、重塑地景、显现大地和框取景致,并以此重新审视在两者关系中地形作为框架的内涵,以便在全球化、碎片化、异质化的世界里,强化地形所带来的想象和体验,使之成为人探求栖居的意义和生活样式的载体。

关键词：地形栖居框架场域景致

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事亲与继志:宋孝宗之“孝”新论

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中山大学学报（社会科学版） 2024年第2期64卷 146-155页

作者：胡斌中国人民大学法学院北京100872

历代史家多以宋孝宗之“孝”仅指孝事高宗,这一意识限制了孝宗践行“恢复”之志。而根据宋孝宗及部分士大夫对于“孝”的阐释,孝宗之“孝”呈现为“事亲”与“继志”、奉养高宗与效法太祖诸多层面交错联结的复杂图景。他们的阐释扭曲了... 详细信息

历代史家多以宋孝宗之“孝”仅指孝事高宗,这一意识限制了孝宗践行“恢复”之志。而根据宋孝宗及部分士大夫对于“孝”的阐释,孝宗之“孝”呈现为“事亲”与“继志”、奉养高宗与效法太祖诸多层面交错联结的复杂图景。他们的阐释扭曲了高宗主张维持和议的本意,强调孝宗只有效法太祖创业,才是继承高宗之志、完成高宗未竟功业的“大孝”。不过,孝宗与这些士大夫却因“恢复”意识的不同,分别提出两种相异的践行“继志之孝”的行动方案:孝宗强调“恢复”即是要立行北伐,多述太祖尚武习劳的故事,并认为“恢复”须审时度势,不必尽循太祖故事;士大夫则强调谋求“恢复”重在整军备战以及革除军政时弊,所述太祖故事多为强调关防制衡的“维持之具”,并认为“太祖创业故事”寓含整军备战的一切良法。

关键词：宋孝宗宋太祖宋高宗 “恢复” 祖宗之法

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口罩污染物苯甲醛的光化学氧化反应的直接质谱监测

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质谱学报 2024年第1期45卷 157-164,I0005页

作者：易曼董淞斌胡斌暨南大学质谱仪器与大气环境研究所广东省大气污染在线源解析系统工程技术研究中心广东广州510632

苯甲醛化学性质活泼,是口罩原料及制造过程中容易产生的有机污染物。本文采用直接质谱技术监测口罩中苯甲醛在光照与臭氧条件下发生的光化学氧化反应中间体及产物,并用全二维气相色谱-质谱进行验证,探究苯甲醛的光化学反应和氧化反应机... 详细信息

苯甲醛化学性质活泼,是口罩原料及制造过程中容易产生的有机污染物。本文采用直接质谱技术监测口罩中苯甲醛在光照与臭氧条件下发生的光化学氧化反应中间体及产物,并用全二维气相色谱-质谱进行验证,探究苯甲醛的光化学反应和氧化反应机制。结果表明,经日光照射、紫外光照射或臭氧处理之后,口罩污染物苯甲醛可以生成二苯甲酮、4-戊烯酸、苯甲酸甲酯和苯甲酸等产物和中间体。口罩中苯甲醛的光化学氧化过程的质谱监测,有望为不同环境条件下口罩污染物的研究与控制提供新途径。

关键词：质谱口罩苯甲醛光化学氧化反应

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从“社会摇”到“科目三”——媒介考古中的舞蹈及其社会流变

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北京舞蹈学院学报 2024年第3期 17-25页

作者：胡彬彬中国人民大学文学院北京100872

新媒体时代盛行的短视频催生了相应的新型舞蹈文化,其中颇为盛行的是以“科目三”为代表的“社会摇”。对“社会摇”进行媒介考古可以发现,其最早的流行可以定位到“美拍”短视频平台,彼时“社会摇”之“社会”的价值重心在于“全民社... 详细信息

新媒体时代盛行的短视频催生了相应的新型舞蹈文化,其中颇为盛行的是以“科目三”为代表的“社会摇”。对“社会摇”进行媒介考古可以发现,其最早的流行可以定位到“美拍”短视频平台,彼时“社会摇”之“社会”的价值重心在于“全民社会摇”的“全民”参与。“快手”时期的“社会摇”则凸显了外国舞蹈文化在与我国东北地区跨文化交流后的耦合形态与社会历史变迁。以“科目三”为代表的新式“社会摇”在“抖音”平台的持续性流行,重塑了短视频时代的流行舞蹈文化形式与新兴生产方式,展现了数字时代人们的社交与情感状况,同时也使社会中“消失的他者”变为“可见的他者”。

关键词：短视频 “科目三” “社会摇” 流行舞蹈文化他者

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Src inhibition rescues FUNDC1-mediated neuronal mitophagy in ischaemic stroke

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Stroke & Vascular Neurology 2024年第4期9卷 367-379,I0022-I0031页

作者： Tianchi Tang Li-bin hu Chao Ding Zhihua Zhang Ning Wang Tingting Wang Hang Zhou Siqi Xia Linfeng Fan Xiong-jie Fu Feng Yan Xiangnan Zhang Gao Chen Jianru Li Department of Neurosurgery Zhejiang University School of Medicine Second Affiliated HospitalHangzhouZhejiangChina 2NeurosurgeryZhejiang University School of Medicine Second Affiliated HospitalHangzhouZhejiangChina 3Zhejiang University School of MedicineHangzhouZhejiangChina 4Zhejiang University Department of PharmacologyHangzhouZhejiangChina

Background Ischaemic stroke triggers neuronal mitophagy,while the involvement of mitophagy receptors in ischaemia/reperfusion(I/R)injury-induced neuronal mitophagy remain not fully ***,we aimed to investigate the involvement of mitophagy receptor FUN14 domain-containing 1(FUNDC1)and its modulation in neuronal mitophagy induced by I/R *** Wild-type and FUNDC1 knockout mice were generated to establish models of neuronal I/R injury,including transient middle cerebral artery occlusion(tMCAO)in vivo and oxygen glucose deprivation/reperfusion in *** outcomes of mice with two genotypes were *** mitophagy was analysed both in vivo and in *** of FUNDC1 and its regulator Src were *** impact of Src on FUNDC1-mediated mitophagy was assessed through administration of Src antagonist *** To our surprise,FUNDC1 knockout mice subjected to tMCAO showed stroke outcomes comparable to those of their wild-type *** neuronal mitophagy could be activated by I/R injury,FUNDC1 deletion did not disrupt neuronal *** activation of FUNDC1,represented by dephosphorylation of Tyr18,was detected in the early stages(within 3hours)of neuronal I/R injury;however,phosphorylated Tyr18 reappeared and even surpassed baseline levels in later stages(after 6hours),accompanied by a decrease in FUNDC1-light chain 3 *** inactivation of FUNDC1 was associated with Src activation,represented by phosphorylation of Tyr416,which changed in parallel with the level of phosphorylated FUNDC1(Tyr18)during neuronal I/R ***,FUNDC1-mediated mitophagy in neurons under I/R conditions can be rescued by pharmacological inhibition of *** FUNDC1 is inactivated by Src during the later stage(after 6hours)of neuronal I/R injury,and rescue of FUNDC1-mediated mitophagy may serve as a potential therapeutic strategy for treating ischaemic stroke.

关键词： FUNDC1 involvement injury

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肯尼亚人口分布空间格局演化及影响因素研究

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世界地理研究 2024年第6期33卷 64-75页

作者：胡彬刘军安徽工程大学人文学院芜湖241000 中铁建南方投资有限公司南京210023

基于肯尼亚四期全国人口普查数据,运用探索性空间数据分析、标准差椭圆、人口偏移-份额等方法,刻画了1989—2019年肯尼亚47个行政单元人口分布的空间格局演变特征,并运用地理探测器模型分析了其影响因素。结果表明:(1)研究期内肯尼亚人... 详细信息

基于肯尼亚四期全国人口普查数据,运用探索性空间数据分析、标准差椭圆、人口偏移-份额等方法,刻画了1989—2019年肯尼亚47个行政单元人口分布的空间格局演变特征,并运用地理探测器模型分析了其影响因素。结果表明:(1)研究期内肯尼亚人口密度的分布格局较为稳定,表现为西南高、东北低,与经济发展水平的分布格局相吻合;(2)人口空间演变趋势以正偏移增长和负偏移增长类型为主,人口分布中心出现在首都内罗毕西北部,整体呈现出向东南方向迁移的特征;(3)自然因素和社会经济因素共同影响着肯尼亚人口分布的空间演变格局。在高程、气候、降水、经济发展水平和交通基础设施建设的影响下,大致形成以内罗毕、维多利亚湖沿岸的基苏木以及沿海第一大港蒙巴萨为核心的人口高密度集群。

关键词：人口空间分布空间格局演化影响因素肯尼亚非洲

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