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Science China Earth Sciences 2010年第3期53卷 327-334页

作者： hsu WeiBiao Faculty of Earth Sciences China University of Geosciences

Miller Range (MIL) 05035 and LaPaz Icefield (LAP) 02224 are unbrecciated lunar basalt meteorites. In this report, we studied their petrography and mineralogy and made in situ uranogenic Pb/Pb dating of Zr-rich minerals. Petrography and mineralogy of these two lunar meteorites are consistent with previous investigations. The zirconolite Pb/Pb age of MIL 05035 is 3851±8 Ma (2σ), in excellent agreement with previous reports. This age suggests that MIL 05035 could be paired with Asuka 881757, a low-Ti mare basalt meteorite. The magmatic event related to MIL 05035 was probably due to the late heavy impact bom- bardment on the moon around 3.9 Ga. One baddeleyite grain in LAP 02224 shows a large variation of Pb/Pb age, from 3109±29 to 3547±21 Ma (2σ), much older than the whole-rock age of the same meteorite (~3.02±0.03 Ga). The other baddeleyite grain in LAP 02224 has an age of 3005±17 Ma (2σ). The result indicates that the minimum crystallization age of LAP 02224 is ~3.55 Ga and the younger ages could reflect late thermal disturbance on U-Pb system.

关键词： Pb/Pb dating SIMS zirconolite and baddeleyite lunar meteorite low-Ti mare basalt

Detecting surface geostrophic currents using wavelet filter from satellite geodesy

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Science China Earth Sciences 2007年第6期50卷 918-926页

作者： hsu HouTse Institute of Geodesy and Geophysics Chinese Academy of Sciences (CAS)

According to the features of spatial spectrum of the dynamic ocean topography (DOT),wavelet filter is proposed to reduce short-wavelength and noise signals in DOT. The surface geostrophic currents calculated from the DOT models filtered by wavelet filter in global and Kuroshio regions show more detailed information than those from the DOT models filtered by Gaussian filter. Based on a satellite gravity field model (CG01C) and a gravity field model (EGM96),combining an altimetry-derived mean sea surface height model (KMSS04),two mean DOT models are estimated. The short-wavelength and noise signals of these two DOT models are removed by using wavelet filter,and the DOT models asso-ciated global mean surface geostrophic current fields are calculated separately. Comparison of the surface geostrophic currents from CG01C and EGM96 model in global,Kuroshio and equatorial Pacific regions with that from oceanography,and comparison of influences of the two gravity models errors on the precision of the surface geostrophic currents velocity show that the accuracy of CG01C model has been greatly improved over pre-existing models at long wavelengths. At large and middle scale,the surface geostrophic current from satellite gravity and satellite altimetry agrees well with that from oceanography,which indicates that ocean currents detected by satellite measurement have reached relatively high precision.

关键词： satellite altimetry satellite gravity wavelet filter geostrophic current

Screening and prevention of hepatitis C virus reactivation during chemotherapy

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World Journal of Gastroenterology 2021年第31期27卷 5181-5188页

作者： Yuan-Rung Li Tsung-Hui Hu wen-Chi Chen Ping-I hsu Hui-Chun Chen Department of Internal Medicine Kaohsiung Veterans General HospitalKaohsiung 813Taiwan Department of Internal Medicine Chang Gung University College of MedicineKaohsiung 833Taiwan Division of Gastroenterology and Hepatology Department of Internal MedicineKaohsiung Veterans General HospitalKaohsiung 813Taiwan Department of Radiation Oncology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 833Taiwan

Hepatitis C virus(HCV)reactivation occurs in 23%of HCV-infected cancer patients receiving ***-three percent of the patients with reactivation of HCV during chemotherapy develop a hepatitis *** of the cancer patients with HCV reactivation have an unremarkable clinical course following an HCV-related hepatitis flare during ***,26%–57%of the cancer patients developing an acute flare of chronic hepatitis C during chemotherapy require unanticipated discontinuation or dose reduction of chemotherapy,which results in deleterious changes in the cancer treatment *** an optimal strategy for HCV screening in cancer patients receiving chemotherapy has not been established,universal pre-chemotherapy HCV testing for patients with hematological malignancies is recommended by current *** the currently approved direct-acting antivirals(DAAs)can be used in cancer patients,but the use of DAAs during chemotherapy should avoid drug–drug interactions between chemotherapy and antiviral *** there are no contraindications or anticipated drug–drug interactions,DAAs treatment can be administered before,during,or after *** conclusion,HCV reactivation occurs in approximately one-fourth of HCV-infected cancer patients receiving *** HCV-related hepatitis flare during chemotherapy may lead to the discontinuation of potentially life-saving ***,universal HCV screening is recommended in hematological malignancy patients before chemotherapy,but there is no evidence-based guideline for other cancer *** treatment can cure HCV infection and prevent HCV reactivation during chemotherapy.

关键词： Hepatitis C virus Chemotherapy Screening Reactivation Hepatitis flare

Process development for producing a food-grade glucose solution from rice straws

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Chinese Journal of Chemical Engineering 2018年第2期26卷 386-392页

作者： Chih-Heng Wang wen-Hua Chen Hwai-Shen Liu Jinn-Tsyy Lai Cheng-Che hsu Ben-Zu Wan Department of Chemical Engineering Norional Taiwan UniversityTaipeiChina Institute of Nuclear Energy Research TaoyuanChina Food Industry Research and Development Institute HsinchuChina

In this paper, processes for producing a food-grade glucose solution through enzymatic hydrolysis of celluloserich solids obtained from rice straws are presented. The rice straws were pretreated by acid-catalyzed steam explosion, and the reaction efficiency, toxicity control, and process economic feasibility were studied. Mass transfer resistance to the hydrolysis reaction was reduced by grinding with glass beads. A higher glucose concentration could be obtained by feeding more cellulose in the hydrolysis reaction; however, this also resulted in the production of undesired byproducts. Thus, a soaking process for the cellulose solids in water was developed to effectively reduce the generation of byproducts in the hydrolysis reaction. The resulting food-grade glucose solution can provide 414 kilocalories per liter, and could be used during a food-shortage crisis in the *** current production cost is estimated to be 0.82 USD·L^(-1).

关键词： Cellulose Enzymatic hydrolysis Food-grade glucose solution Rice straw Biochemical engineering

Spatial and Temporal Features of Regional Variations in Mean Sea Level around taiwan

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Open Journal of Marine Science 2012年第2期2卷 58-65页

作者： Li-Chung Wu Chia Chuen Kao tai-wen hsu Yi-Fung Wang Jong-Hao Wang Coastal Ocean Monitoring Center National Cheng Kung University Tainan Chinese Taipei Department of Hydraulic and Ocean Engineering National Cheng Kung University Tainan Chinese Taipei Water Resources Agency Ministry of Economic Affairs Taipei Chinese Taipei

Satellite altimeter and in-situ tide gauge records are probably the most common means to obtain observational data for the study of changes in mean sea level. In this study, we employed these data to discuss the spatial and temporal features of regional variations in mean sea level around taiwan. The results showed that most of the regional mean sea surface heights (SSH) around taiwan are higher than the global mean sea surface heights. Most of the sea level trends are greater than the global mean sea level trend as well. We obtained diverse distribution results from the altimeter sea level records in neighboring areas by distributions fit, and the altimeter sea level records showed obvious inhomogene- ity. In addition, periodic fluctuations in the records regarding mean sea level were revealed in our study, based on Fourier spectra and wavelet scalograms.

关键词： Sea Level Variations Tide-Gauge Altimeter

Prominent juxtacortical white matter lesion hallmarks NOTCH3-related intracerebral haemorrhage

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Stroke & Vascular Neurology 2022年第1期7卷 38-46页

作者： Chih-Hao Chen Hao-Chia hsu Yu-wen Cheng Ya-Fang Chen Sung-Chun Tang Jiann-Shing Jeng Neurology National Taiwan University HospitalTaipeiTaiwan Department of Neurology National Taiwan University HospitalTaipeiTaiwan Department of Neurology National Taiwan University Hospital Hsinchu BranchHsinchuTaiwan Medical Imaging National Taiwan University HospitalTaipeiTaiwan

Background and purpose NOTCH3 p.R544C mutation accounts for 5%of spontaneous intracerebral haemorrhage(ICH)in East Asian *** investigated whether certain CT features are associated with NOTCH3-related *** Patients with spontaneous ICH from a prospective stroke registry were screened for NOTCH3 p.R544C *** neuroimaging features on the initial non-contrast CT scans selected to predict NOTCH3 p.R544C mutation,including burden of white matter lesion(WML),degree of brain atrophy,number of lacunes,prominent juxtacortical WML and prominent lobar lacunes,were analysed by neuroradiologists blinded to the mutation *** Of 299 patients with spontaneous ICH(mean age,61 years;male,68%;ICH volumes,14.1±17.8 mL),13 patients(4.3%)carried NOTCH3 p.R544C *** clinical features,haematoma size and location were similar between NOTCH3 p.R544C mutation carriers and *** CT scan revealed that patients with NOTCH3 p.R544C mutation had more severe WML and more frequently had prominent juxtacortical WML(69.2%vs 17.8%,p<0.001),and the effects were not driven by ageing as seen in patients without *** juxtacortical WML(area under receiver operating characteristic curve=0.76)outperformed the total WML score and prominent lobar lacunes and significantly predicted NOTCH3 p.R544C mutation in a multivariable-adjusted model(OR,20.9;95%CI 4.94 to 88.6).Conclusion In patients with spontaneous ICH,the severity and topographic distribution of WML can help in identifying potential NOTCH3 mutation-related ICH.

关键词： NOTCH3 intracerebral white

Theory and Modeling of Phase Transformations under Stress in Steel

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材料热处理学报 2004年第5期25卷 1-7页

作者： T.Y. hsu School of Materials Science and Engineering Shanghai Jiao Tong University Shanghai 200030 China

Thermodynamic prediction of the increment of the formation temperature of proeutectoid ferrite by appliedstress is nearly consistent with the wxperfimental *** models for ferrite,pearlite and bainite transformations can be shown as modified Johnson-Mehl-Avrami equation in which parameter b() varies with the level of applied *** effects of tensile and compressive stresses on enhancement of the ferrite/pearlite and bainite transformations are discussed,The necessity and approach of modification of additivity hypothesis are introduced and the results from modified equation in which some parameters are obtained by rfegression of two experimental results or taken from TTT and CCT diagrams of a cerftain steel are superior than that from Scheil’s *** calculation of Ms and nucleation kinetics equations of martensitic transformation under stress are *** of phase trasformations under stress in ferrous alloys is briefly

关键词：钢相位转换受力状态热力学动力学成核现象相加性假设铁合金

Hybrid Nanoelectronics： Future of Computer Technology

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Journal of Computer Science & Technology 2006年第6期21卷 871-886页

作者：王慰刘明 Andrew hsu Electrical and Computer Engineering Department Purdue School of Engineering and Technology Indiana University-Purdue University Indianapolis Indiana 46202 U.S.A. Institute of Microelectronics Chinese Academy of Sciences Beijing 100080 P.R. China Mechanical Engineering Department Purdue School of Engineering and Technology Indiana University-Purdue University Indianapolis Indiana 46202 U.S.A.

Nanotechnology may well prove to be the 21st century＇s new wave of scientific knowledge that transforms people＇s lives. Nanotechnology research activities are booming around the globe. This article reviews the recent progresses made on nanoelectronic research in US and China, and introduces several novel hybrid solutions specifically useful for future computer technology. These exciting new directions will lead to many future inventions, and have a huge impact to research communities and industries.

关键词： nanoelectronics hybrid fault tolerance microelectronics device circuit computer systems

From Pingcheng to Luoyang—Substantiation of the climatic cause for capital relocation of the Beiwei Dynasty

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Progress in Natural Science:Materials International 2004年第8期14卷 77-81页

作者： hsu Shengi China Department of Geography NTNU taipei taiwan

Emperor Tuoba Hong 1) of Beiwei relocated the capital from Pingcheng to Luoyang approximately 1500 years ago. Most historians speculate that his motivation was based on considerations of politics, economics, military, history, and Chinese culture. However, Sima Guang, a famous historian during the Song Dynasty, claimed 1000 years ago that cold climate was the cause of this historical event. In order to assess the credibility of Sima Guang’s claim, this research examines related ancient documents and the recent frost data for a comparative study. It is found that the mean minimum temperature in Pingcheng during 479AD～509AD is estimated to be lower than present minimum temperature by 2.48 ℃ .

关键词： historical climate climate change Tuoba Hong Beiwei Dynasty.

Vlouse sperm acquire a new structure on the apical hoo Juring epididymal maturation

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Asian Journal of Andrology 2013年第4期15卷 523-528,I0009页

作者： Yi-wen Lin Tzu-Han hsu Pauline H Yen lnstitute of Biomedical Sciences Academia Sinica Taipei 11529 China and lnstitute of Cellular and Organismic Biology Academia Sinica Taipei 11529 China

Spermatozoa emerging from the testis undergo a maturation process in the epididymis during which they change morphologically, biochemically and physiologically to gain motility and the ability to fertilize ova. We examined mouse epididymal sperm with immunostaining and transmission electron microscopy （EM） and identified a previously unknown structure on the apical hook. The structure has a coiled configuration around 11 nm in thickness and is present at the tip of each corner of the triangular-rod shaped perforatorium. Surveying sperm isolated from various regions of the epididymis indicated that mouse sperm acquire the hook rim （HR） structure during its passage through the proximal two-thirds of the caput epididymidis. The structure withstands vigorous sonication and harsh chemical treatments and remains intact after the acrosome reaction. Its location and sturdiness suggest a function in protecting the apical hook from mechanical wear during fertilization. Our EM images of epididymal sperm also revealed additional novel structures as well as lateral asymmetry of the sperm head, indicating that mouse sperm head has a structure more complex than previously recognized.

关键词： apical hook epididymal maturation mouse sperm sperm head ultrastructure