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Additive Fine-Line Circuit Process through Catalyst Induced Copper Electroless Plating

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Journal of Mechanics Engineering and Automation 2020年第1期10卷 11-15页

作者： yi-Wei Lin Yu-Ming Wang Wan-ying Lin Lei-yi Chen ying-Fang Chang Hung-yi Lin Jen-Yuan Chang Da-Jeng Yao Ta-hsin Chou Chien-Hung Lien Mechanical and Mechatronics System Research Laboratories Industrial Technology Research InstituteHsinchu 31040TaiwanR.O.C Department of Power Mechanical Engineering National Tsinghua University#101Sec.2Kuang-Fu RoadHsinchu 30013TaiwanR.O.C.

To response the demand for fine line in electronic products,additive manufacturing process integrated printing techniques and deposited methods to reach fine line circuit,with the merits of reduced material wastage,low fabrication costs,and mass production advantage ***,we have developed additive process in fabricating circuit on flexible substrate through catalyst induced copper electroless deposition(ELD)*** additive processes that integrated printing,activation,and metallization were applied to produce fine-line circuit with 5μm line *** sample with ultraviolet(UV)activation shows better conductive property in comparison with the sample without activation after electroless deposited ***,the results indicated that the reaction of catalyst induced electroless copper plating strongly depends on UV *** fine-line circuit exhibits a narrow line width circuit(around 5μm),lower resistance(6.2μΩ·cm),and mass production with low pollution in comparison with lithographic processes(with photoresist and acid pollution)with a high throughput system(R2R system)for the applications of double side flexible printed circuit board(FPCB).

关键词： Additive process fine-line circuit gravure offset printing electroless plating catalyst

On the physical properties of In2O3 films prepared by atomic layer deposition

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On the physical properties of In2O3 films prepared by atomic...

半边旗活性物质5F对非小细胞肺癌NCI-H460细胞IκKβ、IκB、p65及p50 mRNA表达的影响

第六届国际氧化锌及相关材料研讨会

作者： Wei-Hsu Chi hsin-Lun Su Kuo-yi Yen Shao-Cian Li Jyh-Rong Gong Department of Physics National Chung Hsing University

＜正＞Transparent conductive oxides （TCOs） have received great attention in recent years. Among them, Indium oxide （In2O3） exhibits a wide band gap of 3.7 eV at room temperature （RT） and high optical transparenc...

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中草药 2010年第3期41卷 435-439页

作者：刘义 CHEN George G 吕应年 hsin Michael K Y UNDERWOOD Malcolm J 梁念慈广东医学院广东天然药物研究与开发重点实验室广东湛江524023 韦尔斯亲王医院香港中文大学外科系中国香港广东医学院生物化学与分子生物学研究所广东湛江524023

目的从NF-κB信号通路着手探讨半边旗活性物质5F诱导非小细胞肺癌NCI-H460细胞凋亡发生的机制。方法MTT法检测5F对NCI-H460细胞的生长抑制作用;用半定量RT-PCR方法检测NCI-H460细胞IκKβ、IκB、p65及p50mRNA表达水平的变化。结果5F抑... 详细信息

目的从NF-κB信号通路着手探讨半边旗活性物质5F诱导非小细胞肺癌NCI-H460细胞凋亡发生的机制。方法MTT法检测5F对NCI-H460细胞的生长抑制作用;用半定量RT-PCR方法检测NCI-H460细胞IκKβ、IκB、p65及p50mRNA表达水平的变化。结果5F抑制NCI-H460细胞的生长,其效果与5F的质量浓度和作用时间相关,24、48、72h的IC50分别为:21.40、4.52、1.02μg/mL;100μg/mL5F作用NCI-H460细胞6h后能引起IκKβ和IκBmRNA表达水平显著降低(P<0.05);p65和p50mRNA水平在作用3h就发生明显减少(P<0.05)。结论5F诱导NCI-H460细胞凋亡的机制可能是通过抑制核因子-κB(NF-κB)信号通路来实现的。

关键词：半边旗 5F NCI—H460细胞核因子-κB(NF—κB)

中国台湾省居民乳腺癌术后5年死亡率预测模型的研究

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癌症 2018年第1期37卷 33-40页

作者： Su-hsin Huang Joon-Khim Loh Jinn-Tsong Tsai Ming-Feng Houg Hon-yi Shi Department of Nursing Kaohsiung Municipal Hsiao Kang Hospital Kaohsiung Medical University Department of Healthcare Administration and Medical Informatics Kaohsiung Medical University Divison of Neurosurgery Department of Surgery Kaohsiung Medical University Hospital Department of Surgery Kaohsiung Municipal Ta Tung Hospital Department of Computer Science National Pingtung University Division of General & Gastroenterological Surgery Department of Surgery Kaohsiung Municipal Hsiao Kang Hospital Cancer Center Kaohsiung Medical University Hospital and Institute of Clinical Medicine Kaohsiung Medical University Department of Business Management National Sun Yat sen University

背景与目的目前少有采用2年以上的数据分析乳腺癌手术效果的研究。本文旨在研究人工神经网络(artificial neural network, ANN)模型在预测乳腺癌患者术后5年死亡率中的应用,比较ANN模型、多元逻辑回归(multiple logistic regression, M... 详细信息

背景与目的目前少有采用2年以上的数据分析乳腺癌手术效果的研究。本文旨在研究人工神经网络(artificial neural network, ANN)模型在预测乳腺癌患者术后5年死亡率中的应用,比较ANN模型、多元逻辑回归(multiple logistic regression, MLR)模型和Cox回归模型的预测准确度。方法本研究根据1996–2010年接受手术治疗的3632例乳腺癌患者的临床资料,对MLR、Cox和ANN模型进行比较。应用估算数据集测试模型,应用验证数据集评估模型性能,应用灵敏度分析法对预测模型中输入变量的相对显著性进行评价。结果在预测5年死亡率方面ANN模型明显优于MLR和Cox模型,并且综合性能指标更高。研究结果显示,乳腺癌患者术后5年死亡率与年龄、Charlson并发症指数(Charlson comorbidity index, CCI)、化疗、放疗、激素治疗、医院和外科医生的乳腺癌手术量均显著相关(均为P <0.05)。外科医生的乳腺癌手术量是对5年死亡率影响最大(敏感)的变量,其次是医院的乳腺癌手术量、患者年龄和CCI。结论与传统的MLR和Cox模型相比,ANN模型在预测乳腺癌患者术后5年死亡率方面更为准确。本研究中确定的死亡率预测因子也可用于对乳腺癌手术患者进行康复和健康方面的教育。

关键词：乳腺癌手术人工神经网络多重逻辑回归 Cox回归 5年死亡率

Effect of BenthosemapterotumPeptide on Aging in Mice with Oxidative Damage

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Effect of BenthosemapterotumPeptide on Aging in Mice with Ox...

High‑accuracy measurement of Compton scattering in germanium for dark matter searches

International Conference on Bioscience,Biochemistry and Pharmaceutical Sciences(ICBBPS’2012);International Conference on Chemical,Environmental and Biological Sciences(ICCEBS’2012);International Conference on Management,Behavioral Sciences and Economics Issues(ICMBSE’2012);International Conference on Mechanical,Automobile and Robotics Engineering(ICMAR’2012);International Conference on Computational Techniques and Artificial Intelligence(ICCTAI’2012);International Conference on Advances in Electrical and Electronics Engineering(ICAEE’2012)

作者： Huey-Jine Tsai hsin-Fang Chang hsin-Jung Ho Li-Ting Huang Yuan-Chen Chiu yi-Kuan Tsai Ching-Han Lai Jane C-J Chao Department of Food Science National Taiwan Ocean University Seafood Technology Division Fisheries Research Institute Council of Agriculture School of Nutrition and Health Sciences Taipei Medical University Nutrition Research Center Taipei Medical University Hospital

The study investigated the effect of Benthosemapterotumpeptide on aging in mice. Mice aged of 3 monthswere divided into A toE groups. Mice in group B to E were injected with D-galactose, and orally administered Benthosemapterotum peptide at 0, 10, 50, and 100 mg/d, respectively, for 6 weeks after 6-week induction. Group A as the control group was injected with saline without treatment. The results showed that brain-derived neurotrophy factor （BDNF） level in the braindecreased in group B was significantly increased in treated groups. Time to platform in group A, D, and E was significantly less than that in group B. Group A had more correct annulus crossings and latency time in platform than group B. Group C had similar correct annulus crossings and latency time in platform as group A. Therefore, Benthosemapterotum peptideelevates brain BDNF and improves memory function in aging mice.

关键词： aging Benthosemapterotum peptide BDNF

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Nuclear Science and Techniques 2022年第12期33卷 75-87页

作者： Hai‑Tao Jia Shin‑Ted Lin Shu‑Kui Liu hsin‑Chang Chi Muhammed Deniz Chang‑Hao Fang Peng Gu Xi Jiang yi‑Ke Shu Qian‑Yun Li Yu Liu Ren‑Ming‑Jie Li Chen‑Kai Qiao Chang‑Jian Tang Henry Tsz‑King Wong Hao‑Yang Xing Li‑Tao Yang Qian Yue Yu‑Lu Yan Kang‑Kang Zhao Jing‑Jun Zhu College of Physics Sichuan University610065 ChengduChina Department of Physics National Dong Hwa University97401 ShoufengHualienChina Department of Physics Dokuz Eylül University35160 BucaİzmirTurkey Institute of Physics Academia Sinica11529 TaipeiChina Key Laboratory of Particle and Radiation Imaging(Ministry of Education)and Department of Engineering Physics Tsinghua University100084 BeijingChina Institute of Nuclear Science and Technology Sichuan University610065 ChengduChina

Compton scattering with bound electrons contributes to a significant atomic effect in low-momentum transfer,yielding background structures in direct light dark matter searches as well as low-energy rare event *** report the measurement of Compton scattering in low-momentum transfer by implementing a 10-g germanium detector bombarded by a^(137)Cs source with a radioactivity of 8.7 mCi and a scatter photon captured by a cylindrical NaI(Tl)detector.A fully relativistic impulse approximation combined with multi-configuration Dirac–Fock wavefunctions was evaluated,and the scattering function of Geant4 software was replaced by our calculation *** measurements show that the Livermore model with the modified scattering function in Geant4 is in good agreement with the experimental *** is also revealed that atomic many-body effects significantly influence Compton scattering for low-momentum transfer(sub-keV energy transfer).

关键词： Compton scattering experiment Germanium detector Atomic many-body effects Geant4 Dark matter

Long-term survival and prognostic implications of Chinese type 2 diabetic patients with coronary artery disease after coronary artery bypass grafting

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Health 2009年第3期1卷 139-145页

作者： Ming C Hsiung Tao-hsin Tung Chung-yi Chang yi-Cheng Chuang Kuo-Chen Lee Sung-How Sue yi-Pen Chou Richard Hsiung Chien-Ming Huang Chang-Chyi Lin Wei-Hsian yin Mason S Young Jeng Wei 不详

This study was conducted to determine the sur-vival rates of type 2 diabetic patients after coro-nary artery bypass grafting (CABG) surgery, and the prognostic factors related to all-cause mor-tality during a 7-year follow-up. The medical re-cords of 816 type 2 diabetic patients who un-derwent primary, isolated CABG surgery during 1997-2003 were studied. The Kaplan-Meier me- thod and Cox regression were used to estimate survival and the independence of prognostic factors associated with all-cause mortality. One hundred and five out of 816 patients expired during the 7-year period. The overall survival rate was 83.5% (95%CI: 78.7-88.3%). Associated prog- nostic factors varied by gender. For males, but not for females, smoking (RR=3.44, 95%CI: 1.01- 11.70), myocardial infarction (RR=4.77, 95% CI: 1.23-18.86), respiratory failure (RR=4.21, 95% CI: 1.48-7.99), cardiogenic shock (RR=12.58, 95% CI: 3.25-20.77), and congestive heart failure (RR= 3.77, 95%CI: 1.10-13.45) were significantly related to all-cause mortality. Older age at sur-gery (RR= 1.15, 95%CI: 1.04-1.27), emergent op-eration (RR= 21.29, 95%CI: 10.03-39.43), pul-monary ede-ma (RR=7.72, 95%CI: 1.89-15.59), and days of ICU stay (RR=1.05, 95%CI: 1.02-1.09) were significant- ly related to all-cause mortality in females only. In conclusion, several gen-der-related differences were noted pertaining to all-cause mortality and its relationship to smok- ing, myocardial infarction, respiratory failure, cardiogenic shock, congestive heart failure, older age at surgery, emergent operation, pul-monary edema, and days of ICU stay.

关键词： Coronary Artery Bypass Grafting Gender Difference Prognostic Factors Survival Type 2 Diabetes

PROTEOMIC ANALYSIS OF THE RAT ROSTRAL VENTROLATERAL MEDULLA, A NEURAL DETERMINANT FOR BRAIN DEATH

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PROTEOMIC ANALYSIS OF THE RAT ROSTRAL VENTROLATERAL MEDULLA,...

Antecedents and performance consequences of governance structures in R&D alliances

第十五届国际药理学大会

作者： Chou Li-Jer Wu hsin-yi Chang Alice Y.W. Chan Samuel H.H. Institute of Biomedical Sciences National Sun Yat-sen University Kaohsiung China Center for Neuroscience National Sun Yat-sen University Kaohsiung China Center for Neuroscience National Sun Yat-sen University Kaohsiung China Center for Neuroscience National Sun Yat-sen University Kaohsiung China

＜正＞ Our laboratory revealed previously that the rostral ventrolateral medulla （RVLM） is intimately related to the "life and-death" process. This study sets the stage for screening for the multiple pro-life and pro-death programs that may be engaged by the RVLM during the progression towards death. Tissues collected from the ventrolateral medulla of Sprague-Dawley rats under minimal experimental perturbations were subject to two-dimensional electrophoresis and MALDI-TOF mass spectrometry-peptide map fingerprint analysis. The two-dimensional electrophoret-ic gel （pI: 3-10;Mr: ＜ 94 kDa）. on silver staining or colloidal Coomassie Brilliant Blue staining, showed approximately 530 or 230 protein spots. Of 200 spots selected for in-gel digestion followed by database search using measured peptide masses resulted in the identification of 148 proteins in 188 spots. These include structural proteins, or proteins related to transcription and translation, intermediary metabolism, chaperones. signal transduction. apoptosis. protein turnover, and oxidative stress. This information shall form the foundation in our search for the pro-life and pro-death proteins at the RVLM that may participate in brain death.

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Journal of Southeast University(English Edition) 2012年第3期28卷 360-366页

作者：林艺馨荷世平吴学良东南大学土木学院南京210096 台湾大学土木工程学系台北10672 台湾大学国际企业学系台北10672

Traditionally governance structures are classified into ＂hierarchy or market＂ or ＂equity or non-equity.＂ However,such classifications may not be effective in characterizing all governance structures of research and development（R D） ***,the first objective of this study is to investigate why there exist different organizational governance structures in managing R D alliances;the second objective of this study is to give strategic advice in choosing appropriate forms with respect to various characteristics of R D *** the theoretical lens that integrate both transaction cost economics（TCE） and the resource-based view（RBV）,a model that focuses on six major factors is developed for determining governance structure choices,namely,technological uncertainty,cultural difference,asset specificity,technology complementarity,appropriability of the individual firm＇s know-how,and *** R D alliance with higher technological uncertainty,larger cultural differences,and greater concerns for protecting an individual＇s know-how is more likely to adopt non-integrated alliances as the governing *** R D alliance with a higher degree of asset-specificity,greater technology complementarity and greater trust among partnering organizations is more likely to adopt integrated alliances as the governing structure;an R D alliance in the face of lower technological uncertainty will tend to adopt integrated *** more aligned the choice of the governance structure with its determinants,the better the R D alliance will perform,and vice versa.

关键词： organizational governance structure organizational control resource-based review transaction cost economics R& D alliance