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上海中医药大学学报 2009年第6期23卷 1-3页

作者：徐蓉娟上海中医药大学附属龙华医院上海200032

近年来,关于碘摄入过量与甲状腺疾病的发病率增加之间的关系引起了社会各界的广泛关注。中医历代医家治"瘿"多用海藻、昆布等含碘丰富的中药,本文对在治疗甲状腺疾病过程中如何个体化地合理使用富碘中药进行了思考与总结。

关键词：含碘中药甲状腺疾病辨证论治中医药

肾必宁冲剂对肾小球系膜细胞凋亡及bcl-2、ICE基因表达的影响

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上海中医药大学学报 2001年第3期15卷 35-37页

作者：肖黎丁樱张红敏刘运霞上海中医药大学河南中医学院河南郑州450008 河南省安阳市中医药学校附属医院河南安阳455000

为探讨肾必宁冲剂对肾小球系膜细胞凋亡及凋亡相关基因ICE和Bcl 2表达的影响 ,阐明治疗系膜增生性肾病的机制 ,35只大鼠随机分为空白组 (A)、中药高剂量组 (B)、中药中剂量组 (C)、中药低剂量组 (D)、环磷酰胺 (CTX)组(E) ,每组各 7只 ... 详细信息

为探讨肾必宁冲剂对肾小球系膜细胞凋亡及凋亡相关基因ICE和Bcl 2表达的影响 ,阐明治疗系膜增生性肾病的机制 ,35只大鼠随机分为空白组 (A)、中药高剂量组 (B)、中药中剂量组 (C)、中药低剂量组 (D)、环磷酰胺 (CTX)组(E) ,每组各 7只 ,分别予生理盐水 (A组 )、肾必宁冲剂 (B、C、D组 )、CTX胃饲 ,8d后分别处死取血清 ,采用肾小球系膜细胞培养方法进行体外实验研究 ,测定系膜细胞增殖指数 ,观察凋亡细胞核小体DNA的断裂现象 ,并检测其ICE和bcl 2的变化。结果 :加入肾必宁冲剂血清 16h后 ,系膜细胞出现了典型的凋亡征象 ,凋亡率显著高于A组(P 0 .0 5 )。提示肾必宁冲剂可诱导系膜细胞凋亡 ,促进肾小球增殖性病变消散 ,并可能通过调控ICE和bcl

关键词：肾必宁冲剂肾小球系膜细胞细胞凋亡凋亡相关基因

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303例代谢综合征中医证候特征分析

上海中医药杂志 2010年第10期44卷 27-29页

作者：郎卿虞芳华上海中医药大学基础医学院上海201203 上海中医药大学附属曙光医院上海200021

目的研究代谢综合征的中医证候特点。方法对303例代谢综合征患者进行调查,分析其证候特点及其与BMI、血脂的关系。结果代谢综合征以痰湿内蕴型最多见,且痰湿内蕴型代谢综合征的BMI和血脂较高(P<0.05)。结论代谢综合征以痰湿内蕴型最多见... 详细信息

目的研究代谢综合征的中医证候特点。方法对303例代谢综合征患者进行调查,分析其证候特点及其与BMI、血脂的关系。结果代谢综合征以痰湿内蕴型最多见,且痰湿内蕴型代谢综合征的BMI和血脂较高(P<0.05)。结论代谢综合征以痰湿内蕴型最多见,其主要病机为痰湿内蕴。

关键词：代谢综合征痰湿内蕴辨证分型

Guidelines for the Diagnosis and Treatment of Dengue in China

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Infectious Diseases & Immunity 2021年第3期1卷 144-152页

作者： Fuchun Zhang Jianfeng He Jie Peng Xiaoping Tang Chengfeng Qin Hongzhou Lu Xingwang Li Qingquan Liu Hong Zhao Jifang Sheng Guiqiang Wang Society of Infectious Diseases,Society of Tropical medicine and Parasitology,chinese Medical association Society of Emergency medicine,China association of chinese medicine Department of Infectious Diseases Guangzhou Eighth People’s HospitalGuangzhou Medical UniversityGuangzhou 510060China Guangdong Provincial Center for Disease Control and Prevention Guangzhou 511430China Department of Infectious Diseases Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China Department of Virology State Key Laboratory of Pathogen and BiosecurityBeijing Institute of Microbiology and EpidemiologyAcademy of Military Medical SciencesBeijing 100071China shanghai Public Health Clinical Center Shanghai 201508China Department of Infectious Diseases Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Beijing hospital of traditional chinese Medical Beijing 100010China Department of Infectious Diseases Center for Liver DiseasesPeking University First HospitalBeijing 100034China Department of Infectious Diseases The First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003China. 不详

Dengue is the most prevalent and rapidly spreading mosquito-borne viral *** a dengue non-endemic country,China has experienced several dengue outbreaks in recent ***,dengue patients in China display clinical characteristics that are distinct from those of patients in dengue-endemic *** standardize the diagnosis and treatment of dengue fever,the experts at the Society of Infectious Diseases,Society of Tropical medicine and Parasitology of the chinese Medical association,and the Society of Emergency medicine of China association of chinese medicine have developed a guideline after reviewing the following guidelines and data:guidelines for diagnosis,treatment,prevention,and control of dengue(World Health Organization,2009);the guidelines for diagnosis and treatment of dengue(National Health and Family Planning Commission of the People’s Republic of China,2014,Edition 2);health industry standard of the People’s Republic of China“diagnosis for dengue fever(WS216-2018)”;and systemic reports on *** new guideline includes eight aspects:introduction,terminology,epidemiology and prevention,etiology and pathogenesis,clinical features,diagnosis,treatment,and problems to be solved.

关键词： Dengue Diagnosis Treatment Guideline

Molecular Analysis of Leonurus Species in China Based on Nuclear ITS and Chloroplast matK Sequences

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Molecular Analysis of Leonurus Species in China Based on Nuc...

华蟾素注射液应用于介入治疗肝癌的Meta分析

中华中医药学会第十届中药鉴定学术会议暨WHO中药材鉴定方法和技术研讨会

作者： Zhi-Ye Yang,~(*,+) Sheng-Li Pan,~+ Ke-Ke Huo,~■ Bing-Yi Wu~■ and Zhi Chao~§* Guangdong Institute for Drug Control,Guangzhou 510180,China + School of pharmacy,Fudan University,shanghai 200032,China ■ School of Life Sciences,Fudan University,shanghai 200433,China ■ Nanfang hospital,Southern Medical University,Guangzhou 510515,China§School of traditional chinese medicine,Southern Medical University,Guangzhou 510515, China

The genus Leonurus has long been recognized as a natural group,but its interspecific relationship has not yet been studied in the light of sequence *** ITS regions and matK sequences of all subgenera of Leonurus in China were amplified,sequenced and *** generated by maximum parsimony and neighbor-joining methods and division of the genus into two major *** phylogenetic results indicated that *** has the very close phylogenetic relationship with *** and supported the notion that *** acts as the bridge between *** and *** to analysis of the information given by ITS and matK sequences,we as well suggest that ITS sequences would be more suitable to serve as markers for authentication of Herba Leonuri than matK does.

关键词： Leonurus Herba Leonuri ITS matK phylogenic analysis crude drug authentication

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中国新药与临床杂志 2009年第9期28卷 671-674页

作者：周昕杨金坤朱玲琦高峰谢瑞芳顾希钧上海中医药大学附属龙华医院药剂科上海200032 上海中医药大学附属龙华医院肿瘤科上海200032

目的根据现有临床资料评估华蟾素注射液应用于介入治疗肝癌的临床疗效。方法利用Meta分析的方法综合国内2000—2008年华蟾素注射液介入治疗肝癌的临床研究文献10篇,评估治疗缓解率、有效率、1年生存率和2年生存率。结果肝癌病人的缓解... 详细信息

目的根据现有临床资料评估华蟾素注射液应用于介入治疗肝癌的临床疗效。方法利用Meta分析的方法综合国内2000—2008年华蟾素注射液介入治疗肝癌的临床研究文献10篇,评估治疗缓解率、有效率、1年生存率和2年生存率。结果肝癌病人的缓解率基本没有偏倚,有效率、1年生存率和2年生存率的比值比(OR)呈偏态分布;缓解率、有效率、1年生存率及2年生存率经异质性检验P值均大于0.05,可合并研究,采用固定效应模型。其合并OR分别为1.87、2.80、2.55和2.61,95%可信区间分别为1.39～2.52、1.96～3.99、1.90～3.42和1.96～3.48。治疗组的缓解率、有效率、1年生存率和2年生存率均高于对照组,有显著差异。结论华蟾素注射液应用于介入治疗肝癌是有效的。

关键词：肝肿瘤 Meta分析偏倚华蟾素注射破肝动脉介入化疗栓塞

Guidelines on the Diagnosis and Management of Primary Biliary Cholangitis (2021)

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Journal of Clinical and Translational Hepatology 2023年第3期11卷 736-746页

作者： Hong You Weijia Duan Shuxiang Li Tingting Lv Sha Chen Lungen Lu Xiong Ma Ying Han Yuemin Nan Xiaoyuan Xu Zhongping Duan Lai Wei Jidong Jia Hui Zhuang chinese Society of Hepatology,chinese Medical association Liver Research Center Beijing Friendship HospitalCapital Medical University&National Clinical Research Center for Di-gestive DiseasesBeijingChina Department of Gastroenterology First People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Gastroenterology and Hepatology Renji HospitalShanghai Jiao Tong UniversityShanghaiChina Department of Gastroenterology Xijing HospitalFourth Military Medical UniversityXi’anShaanxiChina Department of traditional and Western Medical Hepatology The Third Hospital of Hebei Medical UniversityShijiazhuangHebeiChina Department of Infectious Diseases and Center for Liver Diseases Peking University First Hos-pitalBeijingChina Artificial Liver Center Beijing You-An HospitalCapital Medical UniversityBeijingChina Hepatobil-iary Pancreatic Center Tsinghua Changgung HospitalTsinghua UniversityBeijingChina Department of Microbiology and Infectious Disease Center School of Basic Medical SciencesPeking University Health Science CenterBeijingChina 不详

In 2015, the chinese Society of Hepatology and the chinese Society of Gastroenterology published a consensus on pri-mary biliary cholangitis (PBC). In the past years, numerous clinical studies have been published in the field of PBC. To guide the clinical diagnosis and management of PBC patients, the chinese Society of Hepatology invited a panel of experts to assess the new clinical evidence and formulate the current guidelines.

关键词： Primary biliary cholangitis Guidance Diagnosis Management chinese

神病与痴呆剖辨──试析林水淼论治Alzheimer病的学术思想

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上海中医药大学学报 1999年第4期13卷 17-19页

作者：李亚明张春燕上海华东医院中医科上海200040 上海市东方医院中医科上海200120

根据Alzheimer病（AD）的发病过程及其临床特征.回顾历代中医药文献的有关论述，对林水淼论治AD的学术思想予以总结。认为AD宜归属中医“神病”范畴，与传统中医的“痴呆”、“呆病”主要表现为精神障碍迥异。AD可分为后天识神失常和先... 详细信息

根据Alzheimer病（AD）的发病过程及其临床特征.回顾历代中医药文献的有关论述，对林水淼论治AD的学术思想予以总结。认为AD宜归属中医“神病”范畴，与传统中医的“痴呆”、“呆病”主要表现为精神障碍迥异。AD可分为后天识神失常和先天元神不足两类;心气不足，肾精虚衰.脑失所养，神不归舍是AD发病的内在原因;痰滞瘀阻，蒙蔽神窍，神机失灵是老化过程中促发AD的重要因素，属本虚标实之证。治疗上可分为“阴静”症状为主的心气不足型和“阳动”症状为主的肾精虚衰两型，分别予以调心、补肾之法论治。

关键词：论治 Alzheimer病痴呆心气不足肾精治疗学术思想调心重要因素失常

Timosaponin B-Ⅱ protects against ischemic brain injury in a rat model of transient focal ischemia

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Timosaponin B-Ⅱ protects against ischemic brain injury in a...

Resources Investigation and Ribosomal DNA ITS Sequence Analyses of Medical Plant of Rumex hastatus

第三届中俄国际药理学研讨会

作者： Tie-Jun LI~a Yan QIU~a Yao-Cheng RUI~a Wan-Sheng CHEN~b a Department of Pharmacology,School of pharmacy,Second Military Medical University,325 GuoHe Road,shanghai 200433,China b Department of pharmacy,Changzheng hospital shanghai 200003,China

＜正＞AIM Present experiments were performed to study the possible effect of timosaponin B-Ⅱ,one of the major active components of a traditional chinese herbal drug,the rhizome of Anemarrhenae asphodeloides Bge （Lil...

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Resources Investigation and Ribosomal DNA ITS Sequence Analy...