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Laparoscopic, Endoscopic and Robotic Surgery 2021年第1期4卷 9-13页

作者： jordan S.Dutcher Domenech asbun Mary P.Tice horacio j.asbun john A.Stauffer Mayo Clinic Alix School of Medicine JacksonvilleFLUSA Department of General Surgery Mayo Clinic FloridaJacksonvilleFLUSA Hepatobiliary and Pancreas Surgery Miami Cancer InstituteMiamiFLUSA

Background:Laparoscopic distal pancreatectomy(LDP)has become the preferred approach for surgical management of left sided pancreas *** institution previously published its experience with distal pancreatectomies using a clockwise technique with good *** now reexamine our outcomes across a longer time ***:From August 2008 to November 2020,364 patients underwent LDP by hepatobiliary surgeons(HA and jS).All procedures were performed using the same clockwise approach,which includes the stepwise slow compression *** descriptive analysis of patient demographic,clinical,operative,and pathologic data was ***:Of the 364 patients who underwent LDP using this technique,clinically significant postoperative pancreatic fistula(POPF)was noted in 26(7.1%)patients,while major morbidity and mortality were reported in 9.9%and 0.3%,***-assisted method was required for 18(4.9%)patients and unplanned conversion in 20(5.5%)*** a subset analysis of patients with pancreatic adenocarcinoma(n¼90),POPF was noted in 13(14.4%),with minor complications occurring in 34.4%and major morbidity in 14.4%.Conclusion:LDP with a clockwise approach for dissection,combined with the stepwise slow compression technique results in excellent outcomes,with even lower POPF rates than originally *** analysis of patients with pancreatic adenocarcinoma shows acceptable perioperative outcomes with this technique.

关键词： Laparoscopic distal pancreatectomy Pancreatic ductal adenocarcinoma Outcomes

National trends in resection of the distal pancreas

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World journal of Gastroenterology 2012年第32期18卷 4342-4349页

作者： Armando Rosales-Velderrain Steven P Bowers Ross F Goldberg Tatyan M Clarke Mauricia A Buchanan john A Stauffer horacio j asbun Department of General Surgery Mayo Clinic FloridaJacksonvilleFL 32225United States

AIM:To investigate national trends in distal pancreatectomy(DP) through query of three national patient care ***:From the Nationwide Inpatient Sample(NIS,2003-2009),the National Surgical Quality Improvement Project(NSQIP,2005-2010),and the Surveillance Epidemiology and End Results(SEER,2003-2009) databases using appropriate diagnostic and procedural codes we identified all patients with a diagnosis of a benign or malignant lesion of the body and/or tail of the pancreas that had undergone a partial or distal *** of laparoscopy was defined in NIS by the International Classification of Diseases,Ninth Revision correspondent procedure code;and in NSQIP by the exploratory laparoscopy or unlisted procedure current procedural terminology *** SEER,patients were identified by the International Classification of Diseases for Oncology,Third Edition diagnosis codes and the SEER Program Code Manual,third edition procedure *** analyzed the databases with respect to trends of inpatient outcome metrics,oncologic outcomes,and hospital volumes in patients with lesions of the neck and body of the pancreas that underwent operative ***:NIS,NSQIP and SEER identified 4242,2681 and 11 082 DP resections,***,laparoscopy was utilized in 15%(NIS) and 27%(NSQIP).No significant increase was seen over the course of the *** was performed for malignancy in 59%(NIS) and 66%(NSQIP).Neither patient Body mass index nor comorbidities were associated with operative approach(P = 0.95 and P = 0.96,respectively).Mortality(3% vs 2%,P = 0.05) and reoperation(4% vs 4%,P = 1.0) was not different between laparoscopy and open *** complications(10% vs 15%,P < 0.001),hospital costs [44 741 dollars,interquartile range(IQR) 28 347-74 114 dollars vs 49 792 dollars,IQR 13 299-73 463,P = 0.02] and hospital length of stay(7 d,IQR 4-11 d vs 7 d,IQR 6-10,P < 0.001) were less when laparoscopy was *** and two year sur

关键词：切除术胰腺远端数据库查询教学医院程序代码肿瘤疾病 SEER

Total pancreatectomy: Short- and long-term outcomes at a high-volume pancreas center

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World journal of Gastrointestinal Surgery 2016年第9期8卷 634-642页

作者： Hazem M Zakaria john A Stauffer Massimo Raimondo Timothy A Woodward Michael B Wallace horacio j asbun Department of Hepatopancreatobiliary and Liver Transplantation Surgery National Liver Institute Menoufia University Al-Minufya 22732 Egypt Department of Surgery Mayo Clinic Jacksonville FL 32224 United States Department of Gastroenterology Mayo Clinic Jacksonville FL 32224 United States

AIM To identify the current indications and outcomes of total pancreatectomy at a high-volume center. METHODS A single institutional retrospective study of patients undergoing total pancreatectomy from 1995 to 2014 was *** One hundred and three patients underwent totalpancreatectomy for indications including: Pancreatic ductal adenocarcinoma(n = 42, 40.8%), intraductal papillary mucinous neoplasms(n = 40, 38.8%), chronic pancreatitis(n = 8, 7.8%), pancreatic neuroendocrine tumors(n = 7, 6.8%), and miscellaneous(n = 6, 5.8%). The mean age was 66.2 years, and 59(57.3%) were female. Twenty-four patients(23.3%) underwent a laparoscopic total pancreatectomy. Splenic preservation and portal vein resection and reconstruction were performed in 24(23.3%) and 18 patients(17.5%), respectively. The 90 d major complications, readmission, and mortality rates were 32%, 17.5%, and 6.8% respectively. The 1-, 3-, 5-, and 7-year survival for patients with benign indications were 84%, 82%, 79.5%, and 75.9%, and for malignant indications were 64%, 40.4%, 34.7% and 30.9%, *** Total pancreatectomy, including laparoscopic total pancreatectomy, appears to be an appropriate option for selected patients when treated at a high-volume pancreatic center and through a multispecialty approach.

关键词： Intraductal papillary mucinous neoplasms Laparoscopic total pancreatectomy Pancreatic ductal adenocarcinoma Laparoscopy Pancreas cyst Pancreas cancer

Nonlinear robust H-infinity filtering for a class of uncertain systems via convex optimization

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控制理论与应用（英文版） 2012年第2期10卷 152-158页

作者： Masoud ABBASZADEH horacio j. MARQUEZ United Technologies Research Center East HartfordCT 06108U.S.A. Department of Electrical and Computer Engineering University of AlbertaEdmontonAlbertaCanada T6G 2V4

A new approach for robust H-infinity filtering for a class of Lipschitz nonlinear systems with time-varying uncertainties both in the linear and nonlinear parts of the system is proposed in an LMI framework. The admissible Lipschitz constant of the system and the disturbance attenuation level are maximized simultaneously through convex multi-objective optimization. The resulting H-infinity filter guarantees asymptotic stability of the estimation error dynamics with exponential convergence and is robust against nonlinear additive uncertainty and time-varying parametric uncertainties. Explicit bounds on the nonlinear uncertainty are derived based on norm-wise and element-wise robustness analysis.

关键词： Nonlinear uncertain systems Robust observers Nonlinear H-infinity filtering Convex optimization

Cerium,manganese and cerium/manganese ceramic monolithic *** of VOCs and PM removal

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journal of Rare Earths 2016年第7期34卷 675-682页

作者： COLMAN-LERNER Esteban PELUSO Miguel Andres SAMBETH jorge THOMAS horacio Centro de Investigacion y Desarrollo en Ciencias Aplicadas"Dr.jorge j.Ronco"CONICET CCT La Plata UNLP47 N0 257(1900)La PlataArgentina Fac.de Ciencias Exactas UNLP47 and 115(1900)La PlataArgentina Centro de Investigaciones del Medio Ambiente(CIMA).Facultad de Ciencias Exactas UNLP.47y 115.1900-La Plata Planta Piloto Multiproposito PLAPIMU CICPBA-UNLPC.Centenario and 506M ***Argentina

Ceramic supported cerium, manganese and cerium-manganese catalysts were prepared by direct impregnation of aq precursor, and characterized by scanning electron microscopy （SEM）, X-ray diffraction （XRD）, Brunauer-Emmett-Teller rn （BET）, temperature programmed reduction （Ha-TPR）, X-ray photoelectron spectroscopy （XPS） acidity measurements and elec conductivity. The catalytic activity was evaluated for volatile organic compounds （VOC）（ethanol, methyl ethyl ketone and tol oxidation. Additionally, catalysts were tested in particulate matter （PM） combustion. The characterization results indicated that Ce was in the form of Ce4＋ and Ce3＋, and Mn existed in the form of Mn4＋ and Mn3＋ on the surface of the Mn/AC sample and in the of Mn4＋ in the Ce/Mn/AC monolith. VOC oxidation results revealed that the Ce/Mn/AC sample showed an excellent perforr compared with ceramic supported CeO2 （Ce/AC） and MnO, （Mn/AC） samples. The PM combustion was also higher on Ce/M monoliths. The enhanced catalytic activity was mainly attributed to the Ce and Mn interaction which enhanced the acidity, cond ity and the reducibility of the oxides.

关键词： monolith VOCs MnOx Ce PM clays rare earths

胰腺微创手术迈阿密国际循证指南(2020)

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肝胆外科杂志 2020年第6期28卷 478-480页

作者： asbun Hj 崔笑(译) 耿小平(审校) Division of Hepatobiliary and Pancreas Surgery Miami Cancer Institute Miami FL. Department of Surgery University Hospital Southampton NHS Foundation Trust Southampton UK. Department of Surgery Amsterdam UMC University of Amsterdam Amsterdam the Netherlands. Department of Surgery San Raffaele Hospital Milan Italy. Division of Hepatopancreatobiliary and Endocrine Surgery Virginia Mason Medical Center Seattle VA. Department of Surgery Memorial Sloan Kettering Cancer Center New York City NY. Division of Pancreatic Surgery University Hospital of Verona Verona Italy. Department of Surgery and Department of Clinical and Experimental Medicine Linköping University Linköping Sweden. Division of General and Transplant Surgery University of Pisa Pisa Italy. Department of General and Gastrointestinal Surgery Beth Israel Deaconess Medical Center Boston MA. Department of Surgery Division of Surgical Oncology University of Colorado Denver CO. Department of Abdominal Surgery AC Camargo Cancer Center São Paulo Brazil. Department of Surgery St. Elizabeth's Medical Center Boston MA. Wessex Institute University of Southampton UK. General Surgery and Liver Transplant Unit Department of General Surgery Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy. Department of Surgery Medical School University of Cyprus Cyprus. Department of Surgery Beaujon Hospital Paris France. Department of Surgery University of Oklahoma Oklahoma City OK. The Intervention Centre and Department of HPB Surgery Oslo University Hospital and Institute of Clinical Medicine Faculty of Medicine University of Oslo Oslo Norway. Division of Minimally Invasive General Surgery & Robotic Surgery University of Illinois Chicago IL. Department of Surgery Seoul National University Hospital Seoul South Korea. Department of Surgery Portland Providence Medical Center Portland OR. Department of Surgery University of Texas Southwestern Medical Center Dallas TX. Department of Surgery Nor

国际微创胰腺外科研究组(I-MIPS)基于2019年迈阿密国际微创胰腺手术会议专家共识及既往研究的基础上制定了微创胰腺手术国际性循证指南,对微创胰腺手术规范、技术、开展条件和手术效果等6大议题26个临床热点问题进行了系统评价。对有明... 详细信息

国际微创胰腺外科研究组(I-MIPS)基于2019年迈阿密国际微创胰腺手术会议专家共识及既往研究的基础上制定了微创胰腺手术国际性循证指南,对微创胰腺手术规范、技术、开展条件和手术效果等6大议题26个临床热点问题进行了系统评价。对有明确推荐意见的热点问题予以摘译如下:问题1不考虑适应症,在条件合适时|微创远端胰腺切除术相对开放手术应当优先使用吗?

关键词：胰腺手术循证指南胰腺外科推荐意见开放手术优先使用专家共识迈阿密

Robust H-Filtering for Lipschitz Nonlinear Systems via Multiobjective Optimization

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journal of Signal and Information Processing 2010年第1期1卷 24-34页

作者： Masoud Abbaszadeh horacio j. Marquez 不详

In this paper, a new method of filtering for Lipschitz nonlinear systems is proposed in the form of an LMI optimization problem. The proposed filter has guaranteed decay rate (exponential convergence) and is robust against unknown exogenous disturbance. In addition, thanks to the linearity of the proposed LMIs in the admissible Lipschitz constant, it can be maximized via LMI optimization. This adds an extra important feature to the observer, robustness against nonlinear uncertainty. Explicit bound on the tolerable nonlinear uncertainty is derived. The new LMI formulation also allows optimizations over the disturbance attenuation level ( cost). Then, the admissible Lipschitz constant and the disturbance attenuation level of the filter are simultaneously optimized through LMI multiobjective optimization.

关键词： Lipschitz Nonlinear Systems Optimal Filters Nonlinear Filtering LMI Optimization

Kinematic Decoupled Core Paradigm: Counterrotation or just Warping

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International journal of Astronomy and Astrophysics 2016年第2期6卷 198-205页

作者： Rubén j. Díaz horacio Dottori ICATE CONICET San Juan Argentina Gemini Observatory La Serena Chile Instituto de Física UFRGS Porto Alegre Brazil

Several mechanisms have been proposed in recent years to explain kinematic decoupled cores (KDCs) in early type galaxies as well as the large differences in angular momentum between KDCs and host galaxy. Most of the proposed scenarios involve large fractions of merging events, high speed interactions with dwarf spheroidal galaxies, cusp effect of the dark matter density profiles, etc. We here argue that counterrotation as well as fast and slow rotation of disks or spheroids at the center of galaxies can also be explained by a misalignment of the central spheroid equatorial plane with regard to that defined by the observed external stellar rotation. Contrary to what happens at the outer region of disk galaxies, once instability has led to the inner warped core, the perturbed orbits can maintain a common orientation due to the rigid body like rotation at the central region of the galaxy. The spatial configuration that furnishes the smallest angular momentum difference between the KDC and the host galaxy is completely defined by observed parameters in the plane of the sky, namely, the inclination of the inner and outer disks and the angle between the two lines of nodes. As an example we modeled the paradigmatic and extreme case of the 2D radial velocity field of NGC 4382 nucleus. Tilt angles of the KDC not larger than 30 degrees also allow explaining fast and low rotators of the called “Sauron paradigm” in a unified scenario. The maximum for the three parameters, namely, velocity of the inner rotator, difference of position angle and difference with the outer rotation velocity of the whole Sauron sample, are consistently correlated in agreement with the proposed scenario. These quantities do not correlate with the galaxies magnitude, mass (since large and dwarf spheroidals show apparent counterrotation as well) or environment, also suggesting that an internal phenomenon like the central spheroid warping, that we are here proposing, may be at work.

关键词： Galaxies Disks Counterrotation Inner Warps Kinematics

Nuclear Activity in Circumnuclear Ring Galaxies

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International journal of Astronomy and Astrophysics 2016年第3期6卷 219-235页

作者： María P. Agüero Rubén j. Díaz horacio Dottori Observatorio Astronómico de Córdoba UNCand CONICET Córdoba Argentina ICATE CONICET San Juan Argentina Gemini Observatory La Serena Chile Instituto de Física UFRGS Porto Alegre Brazil

We have analyzed the frequency and properties of the nuclear activity in a sample of galaxies with circumnuclear rings and spirals (CNRs), compiled from published data. From the properties of this sample a typical circumnuclear ring can be characterized as having a median radius of 0.7 kpc (mean 0.8 kpc, rms 0.4 kpc), located at a spiral Sa/Sb galaxy (75% of the hosts), with a bar (44% weak, 37% strong bars). The sample includes 73 emission line rings, 12 dust rings and 9 stellar rings. The sample was compared with a carefully matched control sample of galaxies with very similar global properties but without detected circumnuclear rings. We discuss the relevance of the results in regard to the AGN feeding processes and present the following results: 1) bright companion galaxies seem not to be important for the appearance of CNRs, which appear to be more related to intrinsic properties of the host galaxies or to minor merger processes;2) the proportion of weak bars in galaxies with a CNR is higher than expected;3) the incidence of Seyfert (Sy) activity coeval with CNRs is significantly larger than the rate expected from the morphological distribution of the host galaxies;4) the rate of Sy 2 to Sy 1 type galaxies with CNRs is about three times larger than the expected ratio for galaxies without CNRs and is opposite to that predicted by the geometric paradigm of the classical unified model for AGNs, although it does support the hypothesis that Sy 2 activity is linked to circumnuclear star formation. The possible selection effects of the sample are discussed, and we conclude that the detected trends are strong enough to justify high quality observations of as large as possible set of galaxies with circumnuclear rings and their matched control samples.

关键词： Galaxies Spiral Nuclei Structure Dynamics Active

Modeling the Black Hole Recoil from the Nucleus of M83

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journal of Modern Physics 2013年第7期4卷 55-63页

作者： Guilherme G. Ferrari horacio Dottori Rubén j. Díaz ICATE-CONICET San Juan Argentina Instituto de Física Universidade Federal do Rio Grande do Sul Porto Alegre Brazil

GEMINI + GMOS and Chandra emission-line spectroscopy reveal that the Fanaroff-Riley II radio-source j133658.3-295105 is a local object behind the barred-spiral galaxy M83 that is projected onto the galaxy’s disk at about 60' from the galaxy’s optical nucleus. j133658.3-295105 and its radiolobes are aligned with the optical nucleus of M83 and two other radio-sources neither of which are supernova remnants or HII regions. The optical nucleus of M83 is off-centered by 2.7' (≈60 pc) with regard to the kinematic center. Its mass is within the range (1 -4) × 106 and the velocity dispersion at its center points to a non-resolved mass concentration of ≤106 . In this paper we study the circumstances in which the radio source would have been ejected from the central region of M83. We analyze different types of collisions of binary and triple systems of super-massive black holes (SMBHs) by numerical simulations using a Post-Newtonian approximation of order 7/2 (~1/c7). We developed an N-body code specially built to numerically integrate the Post-Newtonian equations of motion with a symplectic method. Numerical experiments show that the code is robust enough to handle virtually any mass ratio between particles and to follow the interaction up to a SMBH separation of three Schwarzschild radii. We show that within the current Post-Newtonian approximation, a scenario in which one of the three SMBHs suffers a slingshot-like kick is best suited to explain the ejection of j133658.3-295105, which simultaneously produces the recoil of the remaining BH pair, which drags together a subset of stars from the original cluster forming a structure that mimics the off-center optical nucleus of M83. The simulation parameters are tuned to reproduce the velocities and positions of j133658.3-295105 as well as the optical nucleus and the putative SMBH at its center.

关键词： Galaxies Nuclei Dynamics Black Holes Interaction Kick-Off