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Chinese Journal of Electronics 2019年第4期28卷 850-855页

作者： SU Donglin liu hongyi YANG Shunchuan ZHAO Zihua SUI Donghai College of electronic information engineering Beihang University

An efficient analytical method is proposed to calculate the Shielding effectiveness(SE) of an enclosure with an oblique rectangular aperture. This enclosure was first decomposed into two ones with horizontal rectangular apertures through mirror image and Green function theories. The SE of each decomposed enclosure was calculated by the Robinson's method. The relationship between the SE of the original cavity and those of the decomposed ones was also derived analytically. The SE of the original cavity could be directly obtained from this analytical relationship. The accuracy of the proposed method was validated with measurements and the Transmission line matrix(TLM) solver. The results show that the efficiency was largely improved compared with the TLM solver.

关键词： Shielding effectiveness Electromagnetic compatibility Transmission line matrix

Characterization of MHC class Ⅱ A genes in Hainan Eld's deer(Cervus eldi hainanus)

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Chinese Science Bulletin 2013年第17期58卷 2148-2153页

作者： liu hongyi YANG HaiQiong GE YunFa The Key Laboratory of Conservation Biology for Endangered Wildlife of the Ministry of Education and State Conservation Center for Gene Resources of Endangered Wildlife College of Life SciencesZhejiang University

The major histocompatibility complex(MHC) genes play pivotal roles in the immune system of vertebrates against *** are also significant indicators of genetic structure,and are vital to species-level population viability analyses and disease risk *** this study,two DRA and two DQA sequences were isolated from Hainan Eld's deer(Cervus eldi hainanus) using rapid amplification of cDNA ends(RACE) and single-strand conformation polymorphism-heteroduplex(SSCP-HD) *** sequence analysis revealed large differences between the two DQA sequences,especially in their exon 2 regions,but only minimal differences between the variants of the DRA *** of the predicted amino acid sequences of the Ceel-MHC class Ⅱ A variants with those from six other species revealed that these molecules share high homology among ruminants.A phylogenetic tree of four class Ⅱ A sequences from Hainan Eld's deer and the other species placed the newly identified DQA and DRA genes on two distinct branches(100%-supportively),and further divided the two DQA sequences into 98%-supportive DQA1 and 99%-supportive DQA2 clusters,***,this study identified monomorphic Ceel-DQA1 and Ceel-DQA2 genes,and one dimorphic Ceel-DRA gene from Hainan Eld's deer.

关键词：海南坡鹿 MHC 基因核苷酸序列分析主要组织相容性复合体快速扩增cDNA末端种群生存力分析单链构象多态性

Fecal DNA metabarcoding reveals the dietary composition of wintering Red-crowned Cranes(Grus japonensis)

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Avian Research 2023年第4期14卷 647-655页

作者： hongyi liu Wei Xu Nan Xu Wenwen Zhang Haoming Jiang Yongqiang Zhao Changhu Lu Ying Zhu Peng Xu The Co-Innovation Center for Sustainable Forestry in Southern China College of Life SciencesNanjing Forestry UniversityNanjing210037China Administration Station of Castanopsis Kawakamii Nature Reserve in Xinkou of Sanming Sanming365000China Research Center for Biodiversity Conservation and Biosafety State Environmental Protection Scientific Observation and Research Station for Ecological Environment of Wuyi MountainsBiodiversity Comprehensive Observation Station for Wuyi MountainsState Environmental Protection Key Laboratory on BiosafetyNanjing Institute of Environmental SciencesMinistry of Ecology and Environment of ChinaNanjing210042China Jiangsu Yancheng Wetland National Nature Reserve Yancheng224057China Institute of Qinghai Tibetan Plateau Southwest Minzu UniversityChengdu610041China Wetland College Yancheng Teachers UniversityYancheng224051China

Understanding the diet of threatened wildlife is vital for species-specific conservation and habitat management *** Red-crowned Crane(Grus japonensis)is a vulnerable bird distributed in Northeast *** dietary studies of this bird focused mainly on its plant food composition based on field observations and microhistological ***,a total of 45 fecal samples were collected in November,December and January(15 fecal samples each month)from wintering cranes,and then subjected to a high throughput sequencing meta-barcoding approach to determine the primary plant(rbcL)and animal(COI)food items in their diet.A total of 230 operational taxonomic units(OTUs)of plant foods and 371 OTUs of animal foods were *** main plant foods in the wintering period were Miscanthus,Zea,and Hordeum genera,which were similar to those in the breeding and the migration *** agricultural and natural plants were detected,indicating a relatively broad dietary niche for this crane ***,the main animal foods were representatives of Theridiidae,Megascolecidae,and Agelenidae,in sharp contrast to previous *** higher number of small terrestrial arthropods in animal foods might be due to the indirect intake of *** composition of both plant and animal foods in the diet showed the highest diversity in December,while it was homogeneous in *** plant of Zea genus became the main source of nutrition in late winter,as supplementary feeding was performed in the reserve,which could help Red-crowned Cranes to get through the cold *** results obtained in this work would contribute to the development of effective conservation strategies for the Red-crowned Crane.

关键词： Dietary composition Dietary niche Metabarcoding Molecular diet analysis Red-crowned Crane

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种芽生物营养强化机的设计与试验

农机化研究 2025年第1期47卷 87-92页

作者：李菁闫景凤韩休海任洪忱张庆柱孙锦秀李尧刘洪义黑龙江省农业机械工程科学研究院哈尔滨150081

针对营养功能性农产品供给不足和生物营养强化技术装备落后等问题,设计了种芽生物营养强化机。采取提高组分浓度差、压力差,以及透水交变真空等快速催芽技术,解决营养组分向种芽内高效传质问题。经绿豆芽富叶酸营养强化试验和发芽糙米... 详细信息

针对营养功能性农产品供给不足和生物营养强化技术装备落后等问题,设计了种芽生物营养强化机。采取提高组分浓度差、压力差,以及透水交变真空等快速催芽技术,解决营养组分向种芽内高效传质问题。经绿豆芽富叶酸营养强化试验和发芽糙米富钙营养强化试验研究,结果表明:种芽生物营养强化机可生产高营养价值农产品,其生产的绿豆芽中叶酸含量可达1.486 mg/kg,发芽糙米中钙含量可达757 mg/kg,营养强化效果良好。

关键词：种芽生物营养强化机高营养功能农业

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Hemodialysis bilayer bionic blood vessels developed by the mechanical stimulation of hepatitis B viral X(HBX)genetransfected hepatic stellate cells

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第6期25卷 499-512页

作者： hongyi liu Yuanyuan ZHOU Peng GUO Xiongwei ZHENG Weibin CHEN Shichao ZHANG Yu FU Xu ZHOU Zheng WAN Bin ZHAO Yilin ZHAO Department of Oncology and Vascular Interventional Radiology Zhongshan Hospital Affiliated to Xiamen UniversitySchool of MedicineXiamen UniversityXiamen 361004China School of Medicine Xiamen UniversityXiamen 361102China Xiamen Health and Medical Big Data Center Xiamen 361008China Fujian Provincial Key Laboratory of Chronic Liver Disease and Hepatocellular Carcinoma(Zhongshan Hospital Affiliated to Xiamen University) Xiamen 361004China Xiamen Key Laboratory of Cellular Intervention and Interventional Medical Materials Xiamen 361004China

Artificial vascular graft(AVG)fistula is widely used for hemodialysis treatment in patients with renal ***,it has poor elasticity and compliance,leading to stenosis and *** ideal artificial blood vessel for dialysis should replicate the structure and components of a real artery,which is primarily maintained by collagen in the extracellular matrix(ECM)of arterial *** have revealed that in hepatitis B virus(HBV)-induced liver fibrosis,hepatic stellate cells(HSCs)become hyperactive and produce excessive ECM ***,mechanical stimulation can encourage ECM secretion and remodeling of a fiber *** on the above factors,we transfected HSCs with the hepatitis B viral X(HBX)gene for simulating the process of HBV ***,these HBX-HSCs were implanted into a polycaprolactonepolyurethane(PCL-PU)bilayer scaffold in which the inner layer is dense and the outer layer consists of pores,which was mechanically stimulated to promote the secretion of collagen nanofiber from the HBX-HSCs and to facilitate crosslinking with the *** obtained an ECM-PCL-PU composite bionic blood vessel that could act as access for dialysis after ***,the vessel scaffold was implanted into a rabbit’s neck arteriovenous fistula *** exhibited strong tensile strength and smooth blood flow and formed autologous blood vessels in the rabbit’s *** study demonstrates the use of human cells to create biomimetic dialysis blood vessels,providing a novel approach for creating clinical vascular access for dialysis.

关键词： Composite bilayer bionic blood vessel Extracellular matrix(ECM) Hepatic stellate cells(HSCs) Hepatitis B viral X(HBX)gene Mechanical force

Identification and validation of key biomarkers and potential therapeutic targets for primary open-angle glaucoma

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Science China(Life Sciences) 2023年第12期66卷 2837-2850页

作者： Jian Wu Caixia Lin Chenlong Yang Lijie Pan hongyi liu Sirui Zhu Shuwen Wei Xu Jia Qi Zhang Ziyu Yu Xiaofang Zhao Weihai liu Yehong Zhuo Ningli Wang Beijing Institute of Ophthalmology Beijing Tongren Eye CenterBeijing Tongren HospitalCapital Medical UniversityBeijing Key Laboratory of Ophthalmology and Visual SciencesBeijing 100730China Beijing Tongren Eye Center Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Neurosurgery Peking University Third HospitalCenter for Precision Neurosurgery and Oncology of Peking University Health Science CenterBeijing 100191China North America Medical Education Foundation Union City CA 94539USA State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510060China Spencer Center for Vision Research Byers Eye InstituteSchool of MedicineStanford UniversityPalo Alto CA 94304USA

Primary open-angle glaucoma(POAG)is a prevalent cause of blindness worldwide,resulting in degeneration of retinal ganglion cells and permanent damage to the optic ***,the underlying pathogenetic mechanisms of POAG are currently indistinct,and there has been no effective nonsurgical treatment *** objective of this study is to identify novel biomarkers and potential therapeutic targets for *** mRNA expression microarray datasets GSE27276 and GSE138125,as well as the single-cell high-throughput RNA sequencing(sc RNA-seq)dataset GSE148371 were utilized to screen POAGrelated differentially expressed genes(DEGs).Functional enrichment analyses,protein-protein interaction(PPI)analysis,and weighted gene co-expression network analysis(WGCNA)of the DEGs were ***,the hub genes were validated at a single-cell level,where trabecular cells were annotated,and the mRNA expression levels of target genes in different cell clusters were *** and quantitative real-time PCR(q PCR)were performed for further *** analysis identified 43 downregulated and 32 upregulated genes in POAG,which were mainly enriched in immune-related pathways,oxidative stress,and endoplasmic reticulum(ER)*** networks showed that FN1 and DUSP1 were the central hub nodes,while GPX3 and VAV3 were screened out as hub genes through WGCNA and subsequently validated by q ***,FN1,GPX3,and VAV3 were determined to be pivotal core genes via single-cell *** relevant biomarkers involved in the pathogenesis of POAG,may serve as potential therapeutic *** studies are necessary to unveil the mechanisms underlying the expression variations of these genes in POAG.

关键词： primary open-angle glaucoma biomarkers immune response oxidative stress endoplasmic reticulum stress

Limitation of fault-sealing and its control on hydrocarbon accumulation——An example from the Laoyemiao Oilfi eld of the Nanpu Sag

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Petroleum Science 2008年第4期5卷 295-301页

作者： Jiang Zhenxue Dong Yuexia Li hongyi liu Luofu liu Guangdi Li Xiaoying Basin and Reservoir Research Center China University of Petroleum Beijing 102249 China State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum Beijing 102249 China Research Institute of Exploration and Development Jidong Oilfield PetroChina Tangshan Hebei 063004 China School of Resources and Information Technology China University of Petroleum Beijing 102249 China

Based on previous studies on the internal structures of fault belts, the fault belts in the Laoyemiao Oilfield of the Nanpu Sag can be divided into three units, a crushed zone, an upper induced fracture zone and a lower induced fracture zone according to the log response characteristics. The upper induced fracture zone is characterized by the development of pervasive fractures and has a poor sealing or non-sealing capability. It therefore can act as pathways for hydrocarbon migration. The lower induced fracture zone consists of fewer fractures and has limited sealing capability. The crushed zone has a good sealing capability comparable to mudstone and can thus prevent lateral migration of fluid. Through physical modeling and comparing laboratory data with calculated data of oil column heights of traps sealed by faults, it is concluded that the fault-sealing capability for oil and gas is limited. When the oil column height reaches a threshold, oil will spill over from the top of reservoir along the lower induced fracture zone under the action of buoyancy, and the size of reservoir will remain unchanged. Analysis of the formation mechanisms of the fault-sealed reservoirs in the Nanpu Sag indicated that the charging sequence of oil and gas in the reservoir was from lower formation to upper formation, with the fault playing an important role in oil and gas accumulation. The hydrocarbon potential in reverse fault-sealed traps is much better than that in the consequent fault-sealed traps. The reverse fault-sealed traps are favorable and preferred exploration targets.

关键词： Limitation of fault-sealing fault belt oil column height hydrocarbon accumulation Nanpu Sag

Comprehensive characterization of CRC with germline mutations reveals a distinct somatic mutational landscape and elevated cancer risk in the Chinese population

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Cancer Biology & Medicine 2022年第5期19卷 707-732页

作者： Jianfei Yao Yunhuan Zhen Jing Fan Yuan Gong Yumeng Ye Shaohua Guo hongyi liu Xiaoyun Li Guosheng Li Pan Yang Xiaohui Wang Danni liu Tanxiao Huang Huiya Cao Peisu Suo Yuemin Li Jingbo Yu Lele Song Department of Radiotherapy the Eighth Medical Center of the Chinese PLA General HospitalBeijing 100091China HaploX Biotechnology Shenzhen 518057China Department of Colorectal Surgery Affiliated Hospital of Guizhou Medical UniversityGuiyang 550004China International Business School Beijing Foreign Studies UniversityBeijing 100089China Department of Gastroenterology the Second Medical Center of the Chinese PLA General HospitalBeijing 100853China Department of Experimental Pathology Beijing Institute of Radiation MedicineBeijing 100850China Department of General Surgery the First Medical Center of the Chinese PLA General HospitalBeijing 100853China Department of Hepatobiliary Surgery Dalian Municipal Central HospitalDalian Medical UniversityDalian 116033China Comprehensive Liver Cancer Department the Fifth Medical Center of the Chinese PLA General HospitalBeijing 100039China

Objective:Hereditary colorectal cancer(CRC)accounts for approximately 5%–10%of all CRC *** full profile of CRC-related germline mutations and the corresponding somatic mutational profile have not been fully determined in the Chinese ***:We performed the first population study investigating the germline mutation status in more than 1,000(n=1,923)Chinese patients with CRC and examined their relationship with the somatic mutational *** alterations were examined with a 58-gene next-generation sequencing panel,and somatic alterations were examined with a 605-gene ***:A total of 92 pathogenic(P)mutations were identified in 85 patients,and 81 likely pathogenic(LP)germline mutations were identified in 62 patients,accounting for 7.6%(147/1,923)of all ***2 and APC was the most mutated gene in the Lynch syndrome and non-Lynch syndrome groups,*** with P/LP mutations had a significantly higher ratio of microsatellite instability,highly deficient mismatch repair,family history of CRC,and lower *** somatic mutational landscape revealed a significantly higher mutational frequency in the P group and a trend toward higher copy number variations in the non-P *** Lynch syndrome group had a significantly higher mutational frequency and tumor mutational burden than the nonLynch syndrome *** analysis revealed that the Notch signaling pathway was uniquely clustered in the Lynch syndrome group,and the MAPK and cAMP signaling pathways were uniquely clustered in the non-Lynch syndrome *** risk analysis indicated that the overall odds ratio was 11.13(95%CI:8.289–15.44)for the P group and 20.68(95%CI:12.89–33.18)for the LP ***:Distinct features were revealed in Chinese patients with CRC with germline *** Notch signaling pathway was uniquely clustered in the Lynch syndrome group,and the MAPK and cAMP signaling pathways were uniquely clustered in the non-Lynch syndr

关键词： Colorectal cancer germline Lynch syndrome hereditary cancer next-generation sequencing Notch signaling pathway TMB MSI MMR

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圣经的叙事话语

外国文学研究 2006年第6期28卷 139-145页

作者：刘洪一深圳大学

圣经叙事不同于一般叙事的独特之处在于“上帝”对圣经叙事的全面介入并成为圣经叙事推演的驱动因素。因此,圣经形成了一个独特的叙事话语并表现出鲜明的特征,即上帝之道决定了叙事话语的属性,上帝的契约是叙事话语的核心概念,上帝和人... 详细信息

圣经叙事不同于一般叙事的独特之处在于“上帝”对圣经叙事的全面介入并成为圣经叙事推演的驱动因素。因此,圣经形成了一个独特的叙事话语并表现出鲜明的特征,即上帝之道决定了叙事话语的属性,上帝的契约是叙事话语的核心概念,上帝和人则是叙事话语的中心内容。

关键词：圣经上帝叙事话语

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电磁感应加热用于可持续催化技术的研究进展

化工进展 2022年第3期41卷 1440-1452页

作者：刘鸿益杨光星余皓华南理工大学化学与化工学院广东广州510641

电磁感应加热技术作为一种通过吸收电磁能直接转换为热能的非直接接触式加热技术,热量直接在磁性材料上迅速感应产生,无需加热整个反应器,改善了能量传递效率和高散热现象。因此,电磁感应加热为高温化学过程供了独特的解决方案,以克服... 详细信息

电磁感应加热技术作为一种通过吸收电磁能直接转换为热能的非直接接触式加热技术,热量直接在磁性材料上迅速感应产生,无需加热整个反应器,改善了能量传递效率和高散热现象。因此,电磁感应加热为高温化学过程供了独特的解决方案,以克服使用传统加热方法时带来的加热/冷却速率缓慢、加热不均匀、低能效等问题。本文首先简述了电磁感应加热技术的加热机制以及相关的测量方法,重点介绍了电磁感应加热过程中能量效率的评估,进而总结了采用电磁感应加热技术用于高温催化反应的研究进展。最后,提出了对未来电磁感应加热技术应用于工业化过程的展望。

关键词：电磁感应加热交变磁场纳米粒子可持续性催化(作用)

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