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Molecular Plant 2024年第1期17卷 4-7页

作者： Mengqiu Song Wumei wang Chun Ji Shengnan Li Wei Liu Xiaoyu Hul Anhui Feng Shuang Ruan Shiyun Du Huan wang Kui Dai Longbiao Guo Qian Qian hongqi Si Xingming Hu College of Agronomy Anhui Agricultural UniversityHefeiAnhui 230036China State Key Laboratory of Rice Biology China National Rice Research InstituteHangzhouZhejiang 310006China Rice Research Institute Anhui Academy of Agricultural SciencesHefeiAnhui 230031China Jiangxi Modern Seed Industry Co.NanchangJiangxi 330026China

Dear Editor,Utilization of heterosis is fundamental to modern agricultural improvement and contributes significantly to food security and agricultural development(Ouyang et al.,2022).However,heterosis of F,hybrids cannot be stably ***,or asexual reproduction through seeds,offers the potential for the fixation of heterosis in F,hybrids and the formation of clonal offspring,which could have considerable implications for plant breeding and agriculture(Schmidt,2020).But naturally occurring apomixis has never been found in major ***,synthetic apomixis has been successfully generated by inducing incomplete meiotic development combined with parthenogenesis development to produce cloned rice(Oryza sativa)seeds(Khanday et al.,2019;wang et al.,2019;Vernet et al.,2022;Wei et al.,2023).

关键词： sativa fertility breeding

MULTIPLE KERNEL RELEVANCE VECTOR MACHINE FOR GEOSPATIAL OBJECTS DETECTION IN HIGH-RESOLUTION REMOTE SENSING IMAGES

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Journal of Electronics(China) 2012年第5期29卷 353-360页

作者： Li Xiangjuan Sun Xian wang hongqi Li Yu Sun Hao Institute of Electronics Chinese Academy of Sciences Key Laboratory of Technology in Geo-spatial Information Processing and Application System Graduate University Chinese Academy of Sciences

Geospatial objects detection within complex environment is a challenging problem in remote sensing area. In this paper, we derive an extension of the Relevance Vector Machine (RVM) technique to multiple kernel version. The proposed method learns an optimal kernel combination and the associated classifier simultaneously. Two feature types are extracted from images, forming basis kernels. Then these basis kernels are weighted combined and resulted the composite kernel exploits interesting points and appearance information of objects simultaneously. Weights and the detection model are finally learnt by a new algorithm. Experimental results show that the proposed method improve detection accuracy to above 88%, yields good interpretation for the selected subset of features and appears sparser than traditional single-kernel RVMs.

关键词： Object detection Feature extraction Relevance Vector Machine (RVM) Support Vector Machine (SVM) Sliding-window

Mutant rs189037 in ataxia-telangiectasia mutated gene had a negative association with metabolic syndrome but not cognitive decline in centenarians

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Genes & Diseases 2024年第3期11卷 106-108页

作者： Long Feng hongqi Huo Qun Li Tao Yang Yali Zhao Pei Zhang Ping Ping Shihui Fu Department of Anesthesiology Hainan Hospital of Chinese People's Liberation Army General HospitalSanyaHainan 572013China Nuclear Medicine Department Handan Central HospitalHandanHebei056001China Department of Neurosurgery Hainan Hospital of Chinese People's Liberation Army General HospitalSanyaHainan 572013China Department of Oncology Hainan Hospital of Chinese People's Liberation Army General HospitalSanyaHainan 572013China Central Laboratory Hainan Hospital of Chinese People's Liberation Army General HospitalSanyaHainan 572013China School of Life Science Beijing Institute of TechnologyBeijing 100081China General Station for Drug and Instrument Supervision and Control Joint Logistic Support Force of Chinese People's LiberationArmyBeijing 100071China Department of Cardiology Hainan Hospital of Chinese People's Liberation Army General HospitalSanyaHainan 572013China Department of Geriatric Cardiology Chinese People's Liberation Army General HospitalBeijing 100853China

Approximately 20%-25%of adults encounter metabolic syndrome(MetS)worldwide,and MetS is a riskfactorfor cognitive decline(CD)*** with MetS have an 11.48-fold increased incidence of CD compared with those without Mets.^(1) Ataxia-telangiectasia mutated(ATM)gene encodes ATM kinase,which belongs to the phosphatidylinositol 3-hydroxy kinase family.

关键词： ATM development cognitive

Repressing iron overload ameliorates central poststroke pain via the Hdac2-Kv1.2 axis in a rat model of hemorrhagic stroke

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Neural Regeneration Research 2024年第12期19卷 2708-2722页

作者： He Fang Mengjie Li Jingchen Yang Shunping Ma Li Zhang hongqi Yang Qiongyan Tang Jing Cao Weimin Yang Department of Neurology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Department of Molecular Neuropathology Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina Department of Nutrition The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Department of Neurology Henan Provincial People’s HospitalZhengzhouHenan ProvinceChina Department of Human Anatomy School of Basic Medical SciencesZhengzhou UniversityZhengzhouHenan ProvinceChina Neuroscience Research Institute Zhengzhou University Academy of Medical SciencesZhengzhouHenan ProvinceChina

Thalamic hemorrhage can lead to the development of central post-stroke *** in histone acetylation levels,which are regulated by histone deacetylases,affect the excitability of neurons surrounding the hemorrhagic ***,the regulato ry mechanism of histone deacetylases in central post-stroke pain remains unclea ***,we show that iron overload leads to an increase in histone deacetylase 2expression in damaged ventral posterolateral nucleus *** this increase restored histone H3 acetylation in the Kcna2 promoter region of the voltage-dependent potassium(Kv)channel subunit gene in a rat model of central post-stroke pain,thereby increasing Kcna2expression and relieving central ***,in the absence of nerve injury,increasing histone deacetylase 2 expression decreased Kcna2expression,decreased Kv current,increased the excitability of neurons in the ventral posterolateral nucleus area,and led to neuropathic pain ***,treatment with the iron chelator deferiprone effectively reduced iron overload in the ventral posterolateral nucleus after intracerebral hemorrhage,reversed histone deacetylase 2 upregulation and Kv1.2 downregulation,and alleviated mechanical hypersensitivity in central post-stroke pain *** results suggest that histone deacetylase 2 upregulation and Kv1.2 downregulation,mediated by iron overload,are important factors in central post-stroke pain pathogenesis and co uld se rve as new to rgets for central poststroke pain treatment.

关键词： central post-stroke pain hemorrhagic stroke histone deacetylase iron overload voltage-gated potassium ion channel 1.2

NON-PARAMETRIC TOPIC MODEL FOR DISCOVERING GEOGRAPHICAL TOPIC VARIATIONS

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Journal of Electronics(China) 2014年第6期31卷 576-586页

作者： Qi Xiang Huang Yu Song Jun Huang Tinglei wang hongqi Fu Kun Key Laboratory of Technology in Geo-spatial Information Processing and Application System Institute of Electronics Chinese Academy of Sciences University of Chinese Academy of Sciences

This paper presents a non-parametric topic model that captures not only the latent topics in text collections, but also how the topics change over space. Unlike other recent work that relies on either Gaussian assumptions or discretization of locations, here topics are associated with a distance dependent Chinese Restaurant Process(ddC RP), and for each document, the observed words are influenced by the document's GPS-tag. Our model allows both unbound number and flexible distribution of the geographical variations of the topics' content. We develop a Gibbs sampler for the proposal, and compare it with existing models on a real data set basis.

关键词： Text mining Topic model Geographical topics Bayesian non-parameter

Diamond-Like Carbon Depositing on the Surface of Polylactide Membrane for Prevention of Adhesion Formation During Tendon Repair

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Nano-Micro Letters 2024年第9期16卷 478-499页

作者： Yao Xiao Zaijin Tao Yufeng Ju Xiaolu Huang Xinshu Zhang Xiaonan Liu Pavel A.Volotovski Chao Huang hongqi Chen Yaozhong Zhang Shen Liu Department of Orthopaedics Shanghai Jiao Tong University School of Medicine Affiliated Sixth People’s Hospital600 Yishan RdShanghai 200233People’s Republic of China Shanghai Tongji Hospital 389 Xincun RdShanghai 200065People’s Republic of China Key Laboratory for Thin Film and Microfabrication of Ministry of Education Research Institute of Micro/Nano Science and TechnologyShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China Orthopedic Trauma Department Belarus Republic Scientific and Practical Center for Traumatology and OrthopedicsKizhevatova str.60/4220024 MinskBelarus Shanghai Haohai Biological Technology Limited Liability Company 1386 Hongqiao RdShanghai 200336People’s Republic of China Department of General Surgery Shanghai Jiao Tong University School of Medicine Affiliated Sixth People’s Hospital600 Yishan RdShanghai 200233People’s Republic of China Shanghai Key Laboratory for High Temperature Materials and Precision Forming School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Post-traumatic peritendinous adhesion presents a significant challenge in clinical *** study proposes the use of diamond-like carbon(DLC)deposited on polylactic acid(PLA)membranes as a biophysical mechanism for anti-adhesion barrier to encase ruptured tendons in tendon-injured *** results indicate that PLA/DLC composite membrane exhibits more efficient anti-adhesion effect than PLA membrane,with histological score decreasing from 3.12±0.27 to 2.20±0.22 and anti-adhesion effectiveness increasing from 21.61%to 44.72%.Mechanistically,the abundant C=O bond functional groups on the surface of DLC can reduce reactive oxygen species level effectively;thus,the phosphorylation of NF-κB and M1 polarization of macrophages are ***,excessive inflammatory response augmented by M1 macrophage-originated cytokines including interleukin-6(IL-6),interleukin-1β(IL-1β),and tumor necrosis factor-α(TNF-α)is largely *** biocompatibility evaluation,PLA/DLC membrane is slowly absorbed within tissue and displays prolonged barrier effects compared to traditional PLA *** studies show the DLC depositing decelerates the release of degradation product lactic acid and its induction of macrophage M2 polarization by interfering esterase and PLA ester bonds,which further delays the fibrosis *** was found that the PLA/DLC membrane possess an efficient biophysical mechanism for treatment of peritendinous adhesion.

关键词： Diamond-like carbon Reactive oxygen species scavenging Foreign body reaction Biodegradation Antioxidant Peritendinous adhesion

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科技服务业集聚结构特征与区位因素研究

科研管理 2022年第10期43卷 24-32页

作者：王宏起李莹莹王珊珊哈尔滨理工大学经济与管理学院黑龙江哈尔滨150080 浙江财经大学工商管理学院浙江杭州310018

科技服务业集聚结构与功能,与区域创新需求和条件息息相关。运用HDI、区位熵、灰色关联度对我国2003—2018年31个省域科技服务业集聚规模、时空分布态势、结构特征、区位因素进行研究,发现:(1)发达省域科技服务业集聚规模较大,省域间规... 详细信息

科技服务业集聚结构与功能,与区域创新需求和条件息息相关。运用HDI、区位熵、灰色关联度对我国2003—2018年31个省域科技服务业集聚规模、时空分布态势、结构特征、区位因素进行研究,发现:(1)发达省域科技服务业集聚规模较大,省域间规模差距逐渐缩小;(2)研究和试验发展、专业技术、科技推广和应用三类服务业态的专业化集聚分别呈增长-重心东移、降低-重心西移和增长-均匀化趋势;(3)当前各省域集聚结构存在三种形态、两种主要演变趋势和四条演化路径;(4)区位因素对科技服务业集聚结构产生重要影响,但不同服务业态的影响因素存在差异。最后,从省域间服务业梯次联动发展、不同经济水平省域当前服务业发展任务、基于区位因素制定服务业发展政策、服务业重点发展业态四个方面提出对策建议。研究有助于把握我国科技服务业集聚的时空演变规律及区位影响因素,对于各省优化科技服务业发展规划与政策、改善科技服务业集聚结构和提升科技服务水平有积极促进作用。

关键词：科技服务业集聚结构区位因素专业化多样化

In situ TEM observation of magnetization-enhanced dislocation emission and motion for 60Fe40Ni alloy

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Chinese Science Bulletin 1997年第24期42卷 2064-2066页

作者： LI hongqi, wang Yanbin, CHEN Qizhi CHU WuyangDepartment of Materials Physics, University of Science and Technology Beijing, Beijing 100083, China Department of Materials Physics University of Science and Technology Beijing Beijing China

TENSILE test for pure iron in the magnetic field with the intensity of 2 400 A/m indicated thatthe lower yield stress was decreased and the upper yield point disappeared in the magneticfield. This seems to show that magnetization can reduce the resistance of dislocation mo-tion. Up to now, however, direct proof of magnetization-enhanced dislocation emission andmotion is lacking.

关键词： magnetic field dislocation magnetic domain TEM.

前沿技术识别与预测方法研究——基于专利主题相似网络与技术进化法则

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中国科技论坛 2023年第4期 34-42页

作者：武川王宏起王珊珊哈尔滨理工大学经济与管理学院黑龙江哈尔滨150080 浙江财经大学工商管理学院浙江杭州310018

前沿技术是高技术领域内具有指引性、先进性的核心技术,前沿技术的准确识别与预测对技术资源有效配置至关重要。从专利主题相似性的角度设计涵盖离群技术的前沿技术识别方法;引入TRIZ理论技术进化法则(九屏幕法)对未来前沿技术进行预测... 详细信息

前沿技术是高技术领域内具有指引性、先进性的核心技术,前沿技术的准确识别与预测对技术资源有效配置至关重要。从专利主题相似性的角度设计涵盖离群技术的前沿技术识别方法;引入TRIZ理论技术进化法则(九屏幕法)对未来前沿技术进行预测,具体包含确定当前系统、识别技术进化点及延伸性预测3个过程;通过搜集2001—2021年石墨烯专利文本数据,对石墨烯前沿技术进行识别与预测。分析结果表明,本文设计的前沿技术识别方法可弥补传统识别方法完整性不足的问题,能够准确识别离群的非热点前沿技术。前沿技术延伸性预测结果对未来产业技术布局具有重要参考价值。

关键词：前沿技术专利主题相似网络技术进化法则技术识别技术预测

BURST-LDA: A NEW TOPIC MODEL FOR DETECTING BURSTY TOPICS FROM STREAM TEXT

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Journal of Electronics(China) 2014年第6期31卷 565-575页

作者： Qi Xiang Huang Yu Chen Ziyan Liu Xiaoyan Tian Jing Huang Tinglei wang hongqi Key Laboratory of Technology in Geo-spatial Information Processing and Application System Institute of Electronics Chinese Academy of Sciences University of Chinese Academy of Sciences

Topic models such as Latent Dirichlet Allocation(LDA) have been successfully applied to many text mining tasks for extracting topics embedded in corpora. However, existing topic models generally cannot discover bursty topics that experience a sudden increase during a period of time. In this paper, we propose a new topic model named Burst-LDA, which simultaneously discovers topics and reveals their burstiness through explicitly modeling each topic's burst states with a first order Markov chain and using the chain to generate the topic proportion of documents in a Logistic Normal fashion. A Gibbs sampling algorithm is developed for the posterior inference of the proposed model. Experimental results on a news data set show our model can efficiently discover bursty topics, outperforming the state-of-the-art method.

关键词： Text mining Burst detection Topic model Graphical model Bayesian inference