检索结果-南通市图书馆

Journal of Energy Chemistry 2024年第5期92卷 43-51页

作者： Weichen wang Hongke Zhang Yidan wang Fangyuan Zhou Zhiyu Xiang Wanbin Zhu hongliang wang Center of Biomass Engineering College of Agronomy and BiotechnologyChina Agricultural UniversityBeijing 100193China

Optimizing the intrinsic activity of non-noble metal by precisely tailoring electronic structure offers an appealing way to construct cost-effective catalysts for selective biomass ***,we reported a P-doping bifunctional catalyst(Ni-P/mSiO_(2))that achieved 96.6%yield for the hydrogenation rearrangement of furfural to cyclopentanone at mild conditions(1 MPaH_(2),150°C).The turnover frequency of Ni-P/mSiO_(2)was 411.9 h^(-1),which was 3.2-fold than that of Ni/mSiO_(2)(127.2 h^(-1)).Detailed characterizations and differential charge density calculations revealed that the electron-deficient Niδ+species were generated by the electron transfer from Ni to P,which promoted the ring rearrangement *** functional theory calculations illustrated that the presence of P atoms endowed furfural tilted adsorb on the Ni surface by the C=O group and facilitated the desorption of *** work unraveled the connection between the localized electronic structures and the catalytic properties,so as to provide a promising reference for designing advanced catalysts for biomass valorization.

关键词： Furfural Hydrogenation rearrangement P-doping Electron transfer Biomass valorization

Lead-free BiFeO_(3)-BaTiO_(3) based high-Tc ferroelectric ceramics:Antiferroelectric chemical modification leading to high energy storage performance

在线全文

学校读者我要写书评

暂无评论

Journal of Materiomics 2024年第4期10卷 819-827页

作者： hongliang wang Liang Shu Liyu Wei Xin Zhang Qian Li Jing-Feng Li State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing100084China

Dielectric capacitors have been widely used in pulsed power devices owing to their ultrahigh power density,fast charge/discharge speed,and excellent ***,developing lead-free dielectric materials with a combination of high recoverable energy storage density and efficiency remains a ***,a high energy storage density of 7.04 J/cm^(3) as well as a high efficiency of 80.5%is realized in the antiferroelectric Ag(Nb_(0.85)Ta_(0.15))O_(3)-modified BiFeO3-BaTiO3 ferroelectric *** achievement is mainly attributed to the combined effect of a high saturation polarization(Pmax),increased breakdown field(Eb),and reduction of the remnant polarization(Pr).The modification of pseudotetragonal BiFeO3 by Ag(Nb_(0.85)Ta_(0.15))O_(3) leads to a high Pmax,and the enhanced relaxor behavior gives rise to a small *** promoted microstructure(such as a dense structure,fine grains,and compact grain boundaries)after modification results in a high breakdown ***,both the recoverable energy density and efficiency exhibit high stability over a broad range of operating frequencies(1–50 Hz)and working temperatures(25–120℃).These results suggest that the(0.67–x)BiFeO_(3)-0.33BaTiO_(3)-xAg(Nb_(0.85)Ta_(0.15))O_(3) ceramics can be highly competitive as a lead-free relaxor for energy storage applications.

关键词： BiFeO_(3) Lead-free ceramics Dielectric capacitors Energy storage

Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis:Focus on underlying mechanisms and future perspectives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第2期35卷 118-130页

作者： Zihan Liu Han Liu Jialing Cheng hongliang wang Yanfang Yang Jun Ye Yuling Liu State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing 100050China Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation Institute of Materia MedicaChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing 100050China

Ulcerative colitis(UC)is a common progressive inflammatory disease whose incidence has increased rapidly in recent years,and can develop into colorectal cancer in severe *** are currently no adequate or effective treatments for UC due to the fact that some patients have found suboptimal results after repeated administration,while others have experienced adverse *** the rapid development of nanotechnology,developing innovative colon-targeting platforms is essential to improving efficacy,reducing side effects,and improving patient *** this review,we summarize the pathophysiological characteristics of UC and the most recent status of numerous nanodrug delivery systems based on different targeting mechanisms in treating ***,intravenous,and rectal drug delivery nanoparticles targeting the colon are discussed,which can provide ideas for the design of colon-targeting nanoparticles for the treatment of colon diseases,especially for the treatment of *** but not least,we provide a glimpse into the future of colon-targeted delivery systems,as well as future advancements in the field.

关键词： Ulcerative colitis Physiological characteristics Colon-specific drug delivery Mechanisms of action Targeted therapy of UC

Unlocking the potential of amorphous calcium carbonate: A star ascending in the realm of biomedical application

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第2期14卷 602-622页

作者： Han Liu Zhiyang Wen Zihan Liu Yanfang Yang hongliang wang Xuejun Xia Jun Ye Yuling Liu State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050China Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation Institute of Materia MedicaChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050China

Calcium-based biomaterials have been intensively studied in the field of drug delivery owing to their excellent biocompatibility and ***-based materials can also deliver contrast agents,which can enhance real-time imaging and exert a Ca^(2+)-interfering therapeutic *** on these characteristics,amorphous calcium carbonate(ACC),as a brunch of calcium-based biomaterials,has the potential to become a widely used *** functional ACC can be either discovered in natural organisms or obtained by chemical synthesis However,the standalone presence of ACC is unstable in *** are required to be used as stabilizers or core-shell structures formed by permeable layers or lipids with modified molecules constructed to maintain the stability of ACC until the ACC carrier reaches its *** has high chemical instability and can produce biocompatible products when exposed to an acidic condition in vivo,such as Ca^(2+) with an immune-regulating ability and CO_(2) with an imaging-enhancing *** to these characteristics,ACC has been studied for selfsacrificing templates of carrier construction,targeted delivery of oncology drugs,immunomodulation,tumor imaging,tissue engineering,and calcium *** in this paper has been placed on the origin,structural features,and multiple applications of ***,ACC faces many challenges in clinical translation,and long-term basic research is required to overcome these *** hope that this study will contribute to future innovative research on ACC.

关键词： Amorphous calcium carbonate Drugdelivery system Nanoparticle Acid sensitivity Water instability,Tumortherapy Tissue engineering Calcium supplement

Prevalence of Vitamin A Deficiency in Children Aged 6 to 17 Years—Western and Central Rural Areas,China,2012–2021

在线全文

学校读者我要写书评

暂无评论

China CDC weekly 2024年第3期6卷 51-55页

作者： Peipei Xu Juan Xu Wei Cao Titi Yang Qian Gan hongliang wang Ruihe Luo Hui Pan Qian Zhang National Institute for Nutrition and Health Chinese Center for Disease Control and PreventionBeijingChina

What is already known about this topic?Vitamin A deficiency(VAD)is a leading global nutritional concern,ranking among the top four major nutritional deficiencies *** prevalence of VAD is unevenly distributed across various regions,both within China and *** is added by this report?The report adds valuable insights into the vitamin A nutritional status of rural students aged 6–17 years who participated in the Nutrition Improvement Programme for Rural Compulsory Education Students(NIPRCES).Over the decade from 2012 to 2021,there was a modest improvement in vitamin A *** prevalence of VAD and sub-clinical VAD(SVAD)declined as the students *** the majority of the survey years,the incidence of VAD was higher among males and western regions compared to females and central regions,*** are the implications for public health practice?A comprehensive approach,incorporating dietary diversification,nutrition education,and food fortification,should be implemented to prevent VAD and SVAD especially in males,younger children and children in western areas.

关键词： vitamin Rural younger

Simple and versatile in situ thermo-sensitive hydrogel for rectal administration of SZ-A to alleviate inflammation and repair mucosal barrier in ulcerative colitis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第6期35卷 462-468页

作者： Yu Yan Jiawei Song Dongdong Liu Zihan Liu Jialing Cheng Zhiyang Chen Yanfang Yang Weizhe Jiang hongliang wang Jun Ye Yuling Liu State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050China College of Pharmacy Guangxi Medical UniversityNanning 530021China Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation Institute of Materia MedicaChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050China

Ulcerative colitis(UC)is a chronic inflammatory bowel disease characterized by persistent inflammation of the colon and disrupted intestinal *** mori(Sangzhi)alkaloids(SZ-A),derived from twigs of mulberry,were approved by the National Medical Products Administration in 2020 for treating type 2 diabetes *** evidence has confirmed that SZ-A also alleviates non-alcoholic fatty liver disease and ameliorates inflammation,indicating its potential to address inflammation in ***,the treatment of UC faces challenges due to low drug delivery efficiency and short retention *** overcome these challenges,an injectable and adherent in-situ thermo-sensitive hydrogel containing SZ-A was developed for rectal drug delivery,utilizing the thermo-sensitive polymers Poloxamer 407and *** thermo-sensitive hydrogel system was designed with a moderate gelation temperature of 32±0.5℃,a short gelation time of 64 s,a p H range of 7-10,high moisturizing capability exceeding 90%,and moderate mechanical strength of 4-5 *** a rat model with UC,the in situ thermo-sensitive hydrogel significantly extended the retention time at the colonic site and enabled sustained release after rectal *** of UC were markedly reduced following rectal administration of SZ-A thermosensitive ***,the release of inflammatory factors,such as interleukin-1β(IL-1β),IL-6,IL-18,tumor necrosis factor-α(TNF-α),and transforming growth factor-β1(TGF-β1),significantly decreased in the SZ-A thermo-sensitive hydrogel *** integrity of the colonic mucosal barrier was significantly enhanced following the application of SZ-A thermo-sensitive *** conclusion,rectal administration of SZ-A in situ thermo-sensitive hydrogel effectively alleviated UC symptoms,inhibited the secretion of inflammatory factors,and promoted the repair of the colonic mucosal *** approach holds promise as a potential treatment for UC.

关键词： Ulcerative colitis SZ-A Thermo-sensitive hydrogel Rectal administration Alleviation of inflammation Mucosal barrier repair

Study on the Clinical Application of Nutritional Management Combined with Clinical Monitoring of Glycated Albumin in Diabetic Nephropathy Dialysis Patients

在线全文

学校读者我要写书评

暂无评论

Journal of Clinical and Nursing Research 2024年第9期8卷 146-151页

作者： hongliang wang Aixin Shen Shanshan Zhang Na Jin People’s Hospital of Guandu District Kunming 650200Yunnan ProvinceChina

Objective:To explore the clinical application of nutritional management combined with clinical monitoring of glycated albumin(GA)in diabetic nephropathy(DN)dialysis ***:A total of 20 diabetic nephropathy dialysis patients admitted to the People’s Hospital of Guandu District from January 2022 to February 2023 were included in the *** were randomly divided into a conventional group(n=10)and an observation group(n=10).The study evaluated the blood glucose control,nutritional status,dialysis efficacy,and quality of life scores of both ***:Before the intervention,there were no significant differences in fasting plasma glucose(FPG),GA,serum albumin,body mass index(BMI),dialysis efficiency values,urea clearance rate,or quality-of-life scores between the two groups(P>0.05).After the intervention,the observation group showed significantly lower FPG and GA levels,higher serum albumin,dialysis efficiency values,urea clearance rate,and improved quality-of-life scores compared to the conventional group(P0.05).Conclusion:Nutritional management combined with clinical monitoring of glycated albumin has a significant effect on the clinical application of diabetic nephropathy dialysis *** can effectively improve patients’blood glucose control and nutritional status,reduce the risk of complications,and enhance the quality of life,demonstrating clinical value for broader application.

关键词： Nutritional management Glycated albumin Diabetic nephropathy Dialysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

田野与文本:人类学家李安宅的史学研究

民族研究 2024年第3期 64-76,M0004页

作者：汪洪亮四川师范大学历史文化学院成都市610068

李安宅在中国藏学领域取得了卓越成就,在人类学、史学领域也有着突出的贡献。李安宅的代表作《《仪礼》与《礼记》之社会学的研究》《藏族宗教史之实地研究》,分别是其社会学、人类学研究的代表作,事实上也是其基于社会学、人类学视角... 详细信息

李安宅在中国藏学领域取得了卓越成就,在人类学、史学领域也有着突出的贡献。李安宅的代表作《《仪礼》与《礼记》之社会学的研究》《藏族宗教史之实地研究》,分别是其社会学、人类学研究的代表作,事实上也是其基于社会学、人类学视角方法的社会史著作。李安宅具有较强的史学意识,在相关论述中注意以史为证和以史为鉴。李安宅的学术实践,体现了田野与文本的不可偏废,也充分体现了中国人类学与历史学的密切联系。

关键词：李安宅人类学史学研究田野文本

以文化之名:民国时期政学两界对“中国式边疆”现代化的思考

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

云南师范大学学报（哲学社会科学版） 2024年第1期56卷 10-18页

作者：汪洪亮四川师范大学历史文化学院四川成都610068

民国时期政学两界对“边疆”的界定除了基于政治与地理意义外,更多考察其“文化”元素,普遍认为如不从“文化”着眼,无法道尽“边疆的涵义”。这是一种典型的“中国式边疆”,形成了“中国边疆”独特的“边疆性”,由此中国边政内涵也极... 详细信息

民国时期政学两界对“边疆”的界定除了基于政治与地理意义外,更多考察其“文化”元素,普遍认为如不从“文化”着眼,无法道尽“边疆的涵义”。这是一种典型的“中国式边疆”,形成了“中国边疆”独特的“边疆性”,由此中国边政内涵也极为丰富。“边疆性”之形成,既然主要来自“文化”因素,那么边疆现代化的实质就是要消除“边疆性”,让其失去“文化上的意义”。所谓“文化”,包括物质文化和精神文化。消除“边疆性”并非抹杀文化,而是通过发展经济和增进认同,按李安宅的观点,就是要通过物质和精神的“区域分工”,也就是要实现边疆现代化及其与内地的一体化。

关键词：中国式边疆中国式边政 “边疆性”与“文化” 边疆现代化中华民族共同体意识

在线全文

学校读者我要写书评

暂无评论

债权人撤销权的法律效果及其在程序上的实现

比较法研究 2024年第3期 93-107页

作者：王洪亮清华大学法学院

依据《民法典》第542条,诈害行为被撤销的,自始没有法律拘束力。对此,《民法典合同编通则解释》第46条进行了完善,首先规定了债权人有权要求相对人向债务人返还、价值补偿、履行义务,其次构建了债权人在相对人处实现债权的路线图,债权... 详细信息

依据《民法典》第542条,诈害行为被撤销的,自始没有法律拘束力。对此,《民法典合同编通则解释》第46条进行了完善,首先规定了债权人有权要求相对人向债务人返还、价值补偿、履行义务,其次构建了债权人在相对人处实现债权的路线图,债权人可以请求人民法院一并审理撤销之诉与本诉,然后,债权人基于本诉与撤销之诉的胜诉判决可以在该债务人对相对人的权利上进行强制执行。相对于德国法、法国法上的直接请求权模式,强制执行模式存在执行名义不足、不能避免债务人转移财产或与相对人串通不恢复责任财产、过度破坏债务人与相对人法律关系等弊端。在程序上,撤销之诉应以本诉为前提,债务人的其他债权人也要提起本诉与撤销之诉,才可以对相对人的返还请求权进行强制执行,或者参加第一个撤销权人的强制执行程序,参与财产分配。债权人提起的撤销之诉的内容应包含相对人返还标的物或价值补偿给债务人,以及要求债务人将标的物或价值补偿用于清偿债务的内容。在撤销之诉主文上,可以表达为相对人返还标的物或价值补偿给债务人,并要求债务人将标的物或价值补偿用于清偿债务。撤销之诉的判决原则上没有扩张效力。

关键词：债权人撤销权撤销之诉强制执行容忍之诉