检索结果-南通市图书馆

红景天苷改善创伤性脑损伤后继发性神经损伤的作用机制研究进展

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

遵义医科大学学报 2024年第4期47卷 416-423页

作者：陈琳葛红飞喻安永遵义医科大学附属医院急诊科贵州遵义563003 陆军军医大学第一附属医院神经外科重庆400037

创伤性脑损伤(TBI)是由交通事故、跌倒等造成的一种复杂的头部获得性直接损伤,包括原发性脑损伤和继发性脑损伤,其中继发性脑损伤(sTBI)产生的二级生化级联反应(如氧化应激反应、炎症反应、谷氨酸神经毒性反应)是导致神经功能障碍的最... 详细信息

创伤性脑损伤(TBI)是由交通事故、跌倒等造成的一种复杂的头部获得性直接损伤,包括原发性脑损伤和继发性脑损伤,其中继发性脑损伤(sTBI)产生的二级生化级联反应(如氧化应激反应、炎症反应、谷氨酸神经毒性反应)是导致神经功能障碍的最主要原因。红景天苷(Sal)是从红景天根茎中分离出的一种天然酚类产物,具有抗氧化、抑制炎症和凋亡、阻断神经传递等神经保护作用。因其在神经保护中疗效显著,且副反应少,已成为治疗TBI后继发性脑损伤药物中的研究热点。虽然临床上关于sTBI的治疗已有广泛研究,但目前仍缺乏Sal改善sTBI所致神经功能障碍的机制总结,因此本文就Sal改善TBI后继发神经功能障碍的最新研究进展及作用机制作一综述,以期为临床上应用Sal改善此类疾病及其并发症提供参考。

关键词：创伤性脑损伤继发性脑损伤红景天苷氧化应激反应炎症反应谷氨酸兴奋性神经毒性反应

Green synthesis of ZSM-5 using silica fume and catalytic co-cracking of lignin and plastics for production of monocyclic aromatics

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2024年第1期65卷 92-105页

作者： Hongbing Fu Yufei Gu Tianhua Gao Fuwei Li Hengshuo Gu Hucheng ge Yuke Liu Zhixia Li hongfei Lin Jiangfei Cao School of Chemistry and Chemical Engineering Guangxi UniversityNanning 530004China Guangxi Bossco Environmental Protection Technology Co. Ltd.Nanning 530007China School of Environmental and Chemical Engineering Zhaoqing UniversityZhaoqing 526000China

ZSM-5 with hierarchical pore structure was synthesized by a simple two-step hydrothermal crystallization from silica fume without using any organic ammonium templates.The synthesized ZSM-5 were oval shaped particles with a particle size about 2.0 μm and weak acid-dominated with proper Brønsted(B)and Lewis(L)acid sites.The ZSM-5 was used for catalytic co-cracking of n-octane and guaiacol,lowdensity polyethylene(LDPE)and alkali lignin(AL)to enhance the production of benzene,toluene,ethylbenzene and xylene(BTEX).The most significant synergistic effect occurred at n-octane/guaiacol at 1:1 and LDPE/AL at 1:3,under the condition,the achieved BTEX selectivity were 24%and 33%(mass)higher than the calculated values(weighted average).The highest BTEX selectivity reached 88.5%,which was 3.7%and 54.2%higher than those from individual cracking LDPE and AL.The synthesized ZSM-5 exhibited superior catalytic performance compared to the commercial ZSM-5,indicating potential application prospect.

关键词： Silica fume ZSM-5 Catalytic co-cracking Plastics Lignin

Role of temperature in tribolayers in fretting wear ofγ-TiAl alloy

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Friction 2024年第5期12卷 939-953页

作者： Yulei YANG hongfei SHANG Huiping PEI Jimin XU Yi LIANG Minghui PAN School of Mechanical Engineering Nanjing University of Science and TechnologyNanjing210094China State Key Laboratory of Tribology in Advanced Equipment Tsinghua UniversityBeijing100084China Institute of Tribology Hefei University of TechnologyHefei230009China

The formation of tribolayers may play significant influences on fretting wear.At elevated temperature,the adhesion among wear debris and the increased diffusion rate facilitate the formation of tribolayers.However,the intensification of oxidation at elevated temperature and the low diffusion rate in oxides may play an adverse role.The present study aims to investigate the role of temperature in tribolayers in fretting wear using aγ-TiAl alloy.Scanning electron microscope,energy dispersive spectrometer,Raman spectrometer,transmission electron microscope and nanoindentation were utilized to investigate the wear debris,tribolayers,and wear scars.The fretting tests showed that,compared with that at room temperature(RT)and 350℃,significant reduction in wear rate and decrease in the fluctuation of friction coefficient occurred at 550 and 750℃.It was further revealed that when temperature raised from room temperature(RT)to 750℃,the oxidation of the wear debris increased slightly and the diffusion coefficients increased prominently,which facilities the formation of well tribo-sintered tribolayers.The well tribo-sintered tribolayers presented homogenous structure,nanocrystalline grains with excellent mechanical properties,and resulted in the improvement in the fretting wear resistance of theγ-TiAl alloy at 550 and 750℃.

关键词： tribolayer temperature fretting wear γ-TiAl alloy

An interfacial robust and entire self-healing ionogel-elastomer hybrid for elastic electronics enables discretionary assembly and reconfiguration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第4期67卷 1316-1323页

作者： Lei Yang Lijie Sun hongfei Huang Rasoul Esmaeely Neisiany Zhengwei You State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Institute of Functional MaterialsCollege of Materials Science and EngineeringDonghua UniversityResearch Base of Textile Materials for Flexible Electronics and Biomedical Applications(China Textile Engineering Society)Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative MedicineShanghai 201620China Department of Polymer Engineering Hakim Sabzevari UniversitySabzevar ***Iran Biotechnology Centre Silesian University of TechnologyGliwice 44-100Poland

Inspired by the multi-layer architecture of mammal skins,interfacial robust,stretchable,and entirely healable gel-elastomer hybrids hold great potential in diverse fields including biomedical devices,wearable electrical devices,and soft robotics.However,existing gel-elastomer hybrids have numerous limitations including low interfacial bonding toughness,complex and time-consuming preparation process,unhealable,and non-reconfiguration.Herein,we propose a simple and general chemical strategy through the interfacial dynamic bonding between gel and elastomer to simultaneously address the abovementioned obstacles.Dynamic covalent bonds readily and repeatably covalent bonding ionogel and elastomer(interfacial toughness:390 J m^(-2)),endowed the hybrids with entire self-healing features like skin and enabled discretionary assembly and reconfiguration.Moreover,this strategy resolved the troublesome contradiction between interfacial stability and reconfiguration.Taking advantage of the aforementioned features,we readily constructed a multi-module,self-healing,self-powered,and realtime monitoring of personal status integrated elastic electronics,which could simply reconfigure the output signal of elastic electronics into an input signal of the devices-braille keyboard.

关键词： ionogel elastomer interface bonding self-healing dynamic covalent bond

Spatial-temporal shifting patterns and in situ conservation of spotted seal(Phoca largha)populations in the Yellow Sea ecoregion

在线全文

学校读者我要写书评

暂无评论

Integrative Zoology 2024年第2期19卷 307-318页

作者： hongfei ZHUANG Fei SHAO Chao ZHANG Wancai XIA Shouqiang WANG Fangyuan QU Zongling WANG Zhichuang LU Linlin ZHAO Zhaohui ZHANG First Institute of Oceanography Ministry of Natural ResourcesQingdaoChina Department of Natural Resources of Shandong Province Shandong Forestry Protection and Development Service CenterJinanChina National Park(Protected Areas)Development Center National Forestry and Grassland AdministrationBeijingChina College of Life Science China West Normal UniversityNanchongChina Liaoning Ocean and Fisheries Science Research Institute DalianChina

Understanding the habitat shifting pattern is a prerequisite for implementing in situ conservation of migratory species.Spotted seals(Phoca largha)inhabiting the Yellow Sea ecoregion(YSE)comprise a small population with independent genes and represent a charismatic flagship species in this region.However,this population has declined by 80%since the 1940s,and increased support from the countries around the YSE is urgently needed to address the potential local extinction risk.A time-series niche model and life-history weighted systematic conservation planning were designed on the basis of a satellite beacon tracking survey(2010–2020)of the YSE population.The results showed clustering and spreading shifting patterns during the breeding and migratory seasons,respectively.The closed-loop migration route formed in the YSE indicated that this population might be geographically isolated from populations in other breeding areas around the world.The conservation priority area(CPA),with an area of 19632 km^(2)(3.58%of the total YSE area),was the most effective response to the potential in situ risk.However,nearly 80%of the CPA was exposed outside the existing marine protected areas(MPAs).Future establishment of MPAs in China should strategically consider the conservation gap identified herein,and it is recommended for Korea’s closed fishing season to be spatially set in the western Korean Peninsula from May to August.This study also exemplified that the lack of temporal information would lead to the dislocation of niche modeling for migratory species represented by spotted seals.Attention should be paid to protecting small and migratory populations in marine biodiversity conservation planning.

关键词： conservation priority area marine protected area migration seasonal management spotted seal

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

典型工业过程一次颗粒物实时排放特征

煤炭学报 2022年第12期47卷 4375-4387页

作者：葛宏飞孔少飞刘晋宏冯韵凯覃思祁士华中国地质大学环境学院湖北武汉430078 湖北省大气复合污染研究中心湖北武汉430078 中国地质大学生物地质与环境地质国家重点实验室湖北武汉430074

工业过程是我国大气颗粒物的主要来源之一。为满足当前高精度排放清单的构建,亟需对其污染物排放质量浓度的动态变化和排放因子开展实测。基于稀释通道采样系统,对水泥生产、医药制造、玻璃制造、纺织(燃煤锅炉)和钢铁烧结5类典型工业... 详细信息

工业过程是我国大气颗粒物的主要来源之一。为满足当前高精度排放清单的构建,亟需对其污染物排放质量浓度的动态变化和排放因子开展实测。基于稀释通道采样系统,对水泥生产、医药制造、玻璃制造、纺织(燃煤锅炉)和钢铁烧结5类典型工业过程颗粒物进行测试,获得可吸入颗粒物(PM_(10))、细颗粒物(PM_(2.5))、亚微米颗粒物(PM_(1.0))和黑碳(BC)的实时排放量,对PM_(1.0)/PM_(2.5),PM_(2.5)/PM_(10)和BC/PM_(2.5)(质量浓度比)的日变化进行分析,更新各类一次颗粒物的排放因子。上述5类典型工业过程的PM_(2.5)和BC平均日排放质量浓度分别为(1.60±1.13),(5.08±3.29),(0.14±0.12),(0.87±0.42)和(0.79±0.30) mg/m^(3),以及(24.03±16.40),(40.38±20.47),(2.59±1.64),(11.44±10.02)和(5.98±4.33)μg/m^(3),具有明显的日变化,高值时段分别为低值时段的1.16~2.53倍和1.57~2.40倍。这可能与不同时间段内燃料添加改变燃烧状态和污染控制设备效率波动有关,因此高时间分辨率污染物排放清单的构建需考虑这些日变化特征。水泥生产行业的BC/PM_(2.5)为清单编制技术手册中推荐值(0.002)的7.5倍,钢铁烧结行业为推荐值(0.001)的8.6倍,且其BC排放因子分别为0.11和0.02 mg/kg,远低于技术手册中的230和2.52 mg/kg,若以技术手册中推荐的BC排放系数建立排放清单会高估BC的排放量。制药、玻璃制造、纺织(燃煤锅炉)的BC/PM_(2.5)分别为(0.009 5±0.005 0),(0.030 3±0.026 9)和(0.010 2±0.008 0),BC排放因子分别为0.43,0.29和0.68 mg/kg,技术手册中并未给出BC参考排放系数。研究数据可为更新清单编制技术手册和建立BC排放清单提供实测数据支撑。

关键词：工业过程一次颗粒物排放因子黑碳 BC/PM_(2.5)

Enhanced electrochemical performance of Li_(1.3)Al_(0.3)Ti_(1.7)(PO_(4))_(3) solid electrolyte by anion doping

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第3期17卷 1465-1472页

作者： Jingrui Kang Xu Guo Rui Gu Honglei Hao Yi Tang Jiahui Wang Li Jin hongfei Li Xiaoyong Wei Electronic Materials Research Laboratory Key Laboratory of the Ministry of Education&International Center for Dielectric ResearchSchool of Electronic and Information EngineeringXi’an Jiaotong UniversityXi’an 710049China School of Energy and Materials Shanghai Key Laboratory of Engineering Materials Application and EvaluationShanghai Polytechnic UniversityShanghai 201209China

Nowadays,the majority of the studies on the substitution are focused on cations(such as Y^(3+),Ti^(4+),P^(5+),etc.)in Li_(1.3)Al_(0.3)Ti_(1.7)(PO_(4))_(3)(LATP),while there are few studies on the substitution of anion O^(2-).In this work,the modified LATP with a series of LiCl(LATPClx,x=0.1,0.2,0.3,0.4)additives is prepared to enhance ionic conductivity.The successful introduction of Cl-makes the length of the c axis decrease from 20.822(2)to 20.792(1)Å,and the bulk conductivity of 2.13×10^(-3) S·cm^(-1) is achieved in LATPCl_(0.3).Moreover,the Al/Ti-O1/Cl1 and Al/Ti-O_(2)/Cl_(2) distance decrease,while the Li1-O_(2)/Cl_(2) distance increases.Lithium ions migrate more easily in the nanochannel of M3-M1-M3.In addition,the LiCl additive increases the relative density and the grain boundary conductivity of LATPClx compounds.Naturally,a higher ionic conductivity of 2.12×10^(–4) S·cm^(-1) and a low activation energy of 0.30 eV are obtained in LATPCl_(0.3).Correspondingly,the symmetric cell exhibits a low overpotential of±50 mV for over 200 h in LATPCl_(0.3).The solid-state Li|LATPCl_(0.3)|NCM811(NCM811=LiNi0.8Co0.1Mn0.1O_(2))battery exhibits high initial capacity 185.1 mAh·g^(-1) with a capacity retention rate of 95.4%after 100 cycles at 0.5 C.This result suggests that LiCl additive is an effective strategy to promote electrochemical properties of LATP solid electrolyte and can be considered for reference to other inorganic solid electrolytes systems.

关键词： Li_(1.3)Al_(0.3)Ti_(1.7)(PO_(4))_(3)(LATP)solid electrolyte anion doping ionic conductivity cyclic performance

Dielectric polymer grafted electrodes enhanced aqueous supercapacitors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第3期17卷 1525-1534页

作者： Shian Dong Kunming Shi Jie Chen Yingke Zhu hongfei Li Weihang Gao Zhenli Xu Qinglei Liu Xingyi Huang Shanghai Key Laboratory of Electrical Insulation and Thermal Aging Department of Polymer Science and EngineeringState Key Laboratory of Metal Matrix CompositesShanghai Jiao Tong UniversityShanghai 200240China School of Mathematical Sciences Institute of Natural Sciences and MOE−LSCShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240China

Supercapacitors(SCs)have become increasingly important in electrical energy storage and delivery owing to their high power densities and long lifetimes.Aqueous SCs are promising for large-scale engineering applications because of their low cost and safety.However,the low operating voltage and low energy density of aqueous SCs severely limit their practical applications.In this study,a nanoscale dielectric layer is grafted onto a graphene electrode to achieve both a high operating voltage and enhanced capacitance.Compared with an SC without dielectric grafting,a dielectric-enhanced SC(DESC)shows a higher capacitance by 2200%.The mechanism of the capacitance enhancement can be attributed to three factors:the dielectric polarization,the ions desolvation by the dielectric,and the enhanced quantum capacitance from charge transfer and ion adsorption in the polymer molecules.In addition,a 2.5 V pouch DESC with a 1 M KCl electrolyte is confirmed to cycle up to 50,000 times with a capacitance retention of 87.5%.The DESC presents the optimal electrochemical properties after it is grafted with a 5 nm dielectric layer.This study provides new insights into the design of high-voltage and high-energy-density aqueous SCs.

关键词： supercapacitors dielectric polymer high voltage capacitance enhancement

CsRAXs negatively regulate leaf size and fruiting ability through auxin glycosylation in cucumber

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2024年第5期66卷 1024-1037页

作者： Jiacai Chen Liu Liu Guangxin Chen Shaoyun Wang Ye Liu Zeqin Zhang hongfei Li Liming Wang Zhaoyang Zhou Jianyu Zhao Xiaolan Zhang Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops Department of Vegetable SciencesBeijing key Laboratoy of Growtn and Developmental Regul China Agricultural UniversityBeijing 100193China

Leaves are the main photosynthesis organ that directly determines crop yield and biomass.Dissecting the regulatory mechanism of leaf development is crucial for food security and ecosystem turn-over.Here,we identified the novel function of R2R3-MYB transcription factors CsRAXs in regulating cucumber leaf size and fruiting ability.Csrax5 single mutant exhibited enlarged leaf size and stem diameter,and Csrax1/2/5 triple mutant displayed further enlargement phenotype.Overexpression of CsRAX1 or CsRAX5 gave rise to smaller leaf and thinner stem.The fruiting ability of Csrax1/2/5 plants was significantly enhanced,while that of CsRAX5 overexpression lines was greatly weakened.Similarly,cell number and free auxin level were elevated in mutant plants while decreased in overexpression lines.Biochemical data indicated that CsRAX1/5 directly promoted the expression of auxin glucosyltransferase gene CsUGT74E2.Therefore,our data suggested that CsRAXs function as repressors for leaf size development by promoting auxin glycosylation to decrease free auxin level and cell division in cucumber.Our findings provide new gene targets for cucumber breeding with increased leaf size and crop yield.

关键词： auxin glycosylation CsRAXs CsUGT74E2 fruiting ability leaf size