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Agricultural Sciences in China 2007年第6期6卷 762-768页

作者： SUNShu-hong cui zhi-zhong QU Li-xin College of Veterinary Medicine Shandong Agricultural University Taian 271018 P.R.China Shandong Yisheng Animal and Poultry Breeder Company Yantai 264000 P.R.China

To determine if the maternal antibody from breeders vaccinated with cell culture-adapted reticuloendotheliosis virus （REV） could protect chicks from early REV infection, one-day-old chicks with or without anti-REV maternal antibodies were inoculated with REV, and then their growth rates and antibody titers to Newcastle disease virus （NDV） and avian influenza virus （AIV）, after vaccination with inactivated vaccines, were compared. This study indicated that REV infection could cause growth retardation and severely inhibit immune reactions to inactivated vaccines against NDV and Avian influenza virus （AIV, H9 and H5） in one-day-old broilers without maternal antibodies specific to REV. Maternal antibody from breeders vaccinated with an attenuated REV vaccine effectively protected REV-challenged birds from growth retardation and immunosuppression on antibody reactions to NDV and AIV vaccines. Four weeks after vaccination, the HI titers to NDV, AIV-H9, and AIV-H5 in maternal antibody positive and negative groups were 3.36 ＋- 2.04 versus 1.58± 1.69 （P〈0.01）, 6.27±3.87 versus 0.71 ± 1.60 （P〈0.01）, and 6.72±3.92 versus 0.54± 1.44 （P〈0.01）. Maternal antibodies from breeders vaccinated with REV vaccine could successfully protect chicks from REV infection and effectively prevent REV-induced growth retardation and immunosuppression in antibody responses to NDV and AIV.

关键词： reticuloendotheliosis virus Newcastle disease virus avian influenza virus immunosuppression maternal antibody

Transcellular transport characteristics of huperzine alone or in combination with ginkgolide B across Caco-2 and Madin-Darby canine kidney cell monolayer

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Asian Pacific Journal of Tropical Medicine 2014年第11期7卷 889-894页

作者： Wen-cui Zhao zhi-hong Hou Qi Zhang Wei Zheng Pharmacy Department 208th Hospital of PLA. Hospital Office 208th Hospital of PLA. Infirmary 208th Hospital of PLA.

Objective:To study the various processes involved in transcellular transport(TT) of huperzine A alone or in combination with ginkgolide B in Caco-2 and Madin-Darby canine renal(MDCK)cell ***:The transepithelial passage was assayed in the apical-to-basolateral(AP to BL) direction and opposite direction(BL to AP) in both cell *** determination of huperzine A and ginkgolide B were performed by high performance liquid chromatography(HPLC).The passage rates of huperzine A and ginkgolide B were ***-directional TT(absorption and secretion) were taken in huperzine A and ginkgolide B in Caco-2 and MDCK cell ***:TT absorption and secretion kinetics of huperzine A and ginkgolide B across two cells existed at the same *** passage rates of huperzine A were increased significantly with adding different concentrations of ginkgolide ***:The compound preparations of HA in combination with CB for dementia caused by cerebral ischemic have synergistic effects on the pharmacodynamics,and improve the bioavailability through BBB.

关键词： Caco-2 Huperzine A Ginkgohde B Madin-Darby canine renal Transcellular Transport

Constructing 2D bismuth-based heterostructure for highly efficient photocatalytic CO2 reduction

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Tungsten 2025年第1期 71-79页

作者： Ruo-Hang Xu Hao-Yu Jiang Dan-Dan cui Kun-Rong Du hong-Run Zhang Sheng-Jie Xu Ya-Qi Li zhi-Zhen Ren Liang Wang Wei-Chang Hao Yi Du School of Physics and BUAA-UOW Joint Research Centre Beihang University Shenzhen Institute of Beihang University Centre for Catalysis and Clean Energy School of Environment and Science Griffith University

Reforming carbon dioxide（CO2） into fuels and valuable chemicals using solar energy holds significant potential for emission reduction and addressing energy supply *** recombination of photocarriers remains a major obstacle,however,to enhancing solar energy conversion efficiency in the photocatalytic reaction *** two-dimensional materials,constructing heterogeneous structures has emerged as an effective strategy to enhance the separation of photoexcited carriers by leveraging the internal electric field at the heterogeneous ***,we present a facile strategy for preparing Bi4NbO8Br/Bi2WO6plate-on-plate Z-scheme junctions with a strong internal electric field by in situ *** unique heterostructure facilitates efficient separation and transport of photoexcited charges by harnessing the internal electric field induced by chemical bonding at the lateral ***,the Bi4NbO8Br/Bi2WO6heterostructure exhibits enhanced CO2photoreduction properties,along with a CO yield rate of approximately 35 μmol·g-1·h-1under full light *** work offers novel insights into the synthesis of unique hetero structures intended to enhance the efficiency of photocatalytic CO2reduction.

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4d金属掺杂MoS_(2)改善对NO_(2)传感性能的机理研究

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原子与分子物理学报 2025年第2期42卷 175-181页

作者：潘一翠罗磊高鑫付岳牟芷瑶朱洪强冯庆重庆师范大学物理与电子工程学院重庆401331 重庆市光电功能材料重点实验室重庆401331

二硫化钼(MoS_(2))是一种热门的气体传感器材料.针对MoS_(2)与气体分子之间的弱相互作用问题,掺杂是一种有效的解决方式.本文利用基于密度泛函理论(DFT)的第一性原理平面波超软赝势计算方法,对二氧化氮(NO_(2))分子在4d金属掺杂后的MoS_... 详细信息

二硫化钼(MoS_(2))是一种热门的气体传感器材料.针对MoS_(2)与气体分子之间的弱相互作用问题,掺杂是一种有效的解决方式.本文利用基于密度泛函理论(DFT)的第一性原理平面波超软赝势计算方法,对二氧化氮(NO_(2))分子在4d金属掺杂后的MoS_(2)表面上吸附的微观机制进行了理论研究.研究结果表明:4d过渡金属元素掺杂有利于提高MoS_(2)吸附NO_(2)后的稳定性,且掺杂改变了材料表面的还原性,改善了其传感性能.掺入4d金属原子的材料禁带宽度显著减小,并且在费米能级附近形成了新的杂质峰,这大大提升了它的导电性.且掺杂原子的4d与5s轨道电子之间的协同作用会提升气体分子与材料之间的传感特性,这表明4d金属原子掺入MoS_(2)可以成为一种有效的NO_(2)传感器材料.本文的工作有助于寻求合适的化学掺杂的方法来提高MoS_(2)基气体传感器的性能.

关键词： MoS_(2) NO_(2) 吸附掺杂第一性原理计算

One-step synthesis of organic microwire-disk interconnected structure for miniaturized channel filters

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Chinese Chemical Letters 2017年第3期28卷 563-568页

作者： Qiu-hong cui Lan Peng zhi-Dong Lou Yu-Feng Hu Feng Teng Key Laboratory of Luminescence and Optical Information Ministry of Education School of Science Beijing Jiaotong University Beijing 100044 China

Miniaturized channel filters are in high demand for many applications such as photonic integrated circuits, information-based technology, and platforms for investigation of light–matter ***, several photonic schemes have been proposed to achieve nanofilters, which require sophisticated growth techniques. Here, we have fabricated microdisk whispering-gallery-mode（WGM） resonators through controlled assembly of organic materials with an emulsion-solventevaporation method. Based on this emulsion assembly method, the diameters of microdisks can be easily controlled, and more importantly, a microwire-disk interconnected structure is able to be constructed via one-step assembly. This microwire-waveguide-connected microdisk heterostructure can be utilized as a channel drop filter. Our results have demonstrated a facile way to achieve flexible WGM-based photonic components which can be integrated with other functional devices.

关键词： Self-assembly Organic nanostructures WGM resonators Heterostructures Channel drop filters

Characterization of Two Putative Protein Phosphatase Genes and Their Involvement in Phosphorus Efficiency in Phaseolus vulgaris

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Journal of Integrative Plant Biology 2012年第6期54卷 400-411页

作者： cui-Yue Liang zhi-Jian Chen Zhu-Fang Yao Jiang Tian hong Liao State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources Root Biology CenterSouth China Agricultura UniversityGuangzhou 510642China Robert Holley Center for Agriculture and Health United States Department of AgricultureAgricultural Research ServiceCornell UniversityIthacaNew York 14853USA

Protein dephosphorylation mediated by protein phosphatases plays a major role in signal transduction of plant responses to environmental stresses. In this study, two putative protein phosphatases, PvPS2：1 and PvPS2：2 were identified and characterized in bean （Phaseolus vulgaris）. The two PvPS2 members were found to be localized to the plasma membrane and the nucleus by transient expression of PvPS2：GFP in onion epidermal cells. Transcripts of the two PvPS2 genes were significantly increased by phosphate （P1） starvation in the two bean genotypes, G19833 （a P-efficient genotype） and DOR364 （a P-inefficient genotype）. However, G19833 exhibited higher PvPS2：1 expression levels than DOR364 in both leaves and roots during P1 starvation. Increased transcription of PvPS2：1 in response to P1 starvation was further verified through histochemical analysis of PvPS2：I promoter fusion b-glucuronidase （GUS） in transgenic Arabidopsis plants. Analysis of PvPS2：1 overexpression lines in bean hairy roots and Arabidopsis showed that PvS2：1 was involved in root growth and P accumulation. Furthermore, expression levels of two P1 starvation responsive genes were upregulated and the APase activities were enhanced in the overexpressing PvPS2：1 Arabidopsis lines. Taken together, our results strongly suggested that PvPS2：1 positively regulated plant responses to P1 starvation, and could be further targeted as a candidate gene to improve crop P efficiency.

关键词： Phosphorus efficiency HAD protein acid phosphatase bean.

A 4-aminonaphthalimide based environmentally sensitive fluorescence probe

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Chinese Chemical Letters 2013年第5期24卷 359-361页

作者： zhi-Yong Wu Jing-Nan cui Xu-hong Qian Tian-Yu Liu State Key Laboratory of Fine Chemicals Dalian University of Technology Shanghai Key Laboratory of Chemical Biology East China University of Science and Technology

A simply synthesized 4-aminonaphthalimide derivative 1 expresses both polarity and viscosity sensitive fluorescence spectra,indicating its potential usage as an environmentally sensitive fluorescence probe. By comparing the fluorescence behavior of 1 with that of a known 4-aminonaphthalimide derivative 2,it was found that the substitution of the 4-amino group has profound influence on the environmentally sensitive fluorescence properties of 4-aminonaphthalimide.

关键词： 4-Aminonaphthalimide Environmentally sensitive Fluorescence probe Substitution effects

Proposal of new classification for postoperative patients with hepatocellular carcinoma based on tumor growth characteristics

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World Journal of Gastroenterology 2013年第33期19卷 5534-5541页

作者： cui-hong Zhu Xiao-Hui Liu Rui Cao Xiong-zhi Wu ZhongShan-Men in-Patient Department Tianjin Medical University Cancer Institute and Hospital

AIM:To propose an appropriate staging system for hepatocellular carcinoma(HCC)***:Here,288 in-patients with HCC were studied and divided into three groups:those with expansive growth,invasive growth(including satellite nodules,nodule fusions and direct tumor invasion of adjacent organs),or disseminative growth(including vascular involvement,regional lymph node metastasis and distant metastasis).A survival analysis was performed using a Kaplan-Meier analysis,and prognostic factors for overall survival were determined by the Cox proportional hazards regression ***:The overall survival(OS)of patients with invasive tumor growth was shorter than that of patients with expansive tumor growth(27.796±3.730and 57.398±4.873 mo,respectively,P<0.001).No significant difference in survival was observed between patients with vascular involvement and patients with regional lymph node metastasis(21.667±4.773 and14.619±2.456 mo,respectively,P=0.801).The OS of patients with distant metastasis(6.417±1.395mo)was shorter than that of the other groups(P<0.001).No significant difference in survival was observed between patients with expansive tumor growth and vascular and/or regional lymph node involvement and patients with invasive tumor growth and no vascular and/or lymph node involvement(25.762±7.024,21.200±7.794 and 39.533±5.840 mo,respectively;P=0.871,0.307 and 0.563,respectively).CONCLUSION:These data led to the proposal of a new staging system:the Expansive-Invasive-Disseminative growth staging classification.

关键词： Hepatocellular carcinoma Lymph node Metastasis Invasive growth Staging system classification

Sublingual Nodules:Diagnostic Markers of Metastatic Breast Cancer

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Chinese Journal of Integrative Medicine 2018年第10期24卷 741-745页

作者： YANG Xue ZHU cui-hong CAO Rui HAO Jian WU Xiong-zhi Tianjin Medical University Cancer Institute and Hospital National Clinical Center for Cancer Key Laboratory of Cancer Prevention and Therapy Department of Medical Oncology Tianjin Medical Universty General Hospital Zhong-Shan-Men In-patient Department Tianjin Medical University Cancer Institute and Hospital

Objective： To evaluate the diagnostic significance of sublingual nodules for metastasis of patients with breast cancer and further to explore the mechanisms of sublingual nodules. Methods： The image data of 117 in-patients with breast cancer in stage I -IV in Tianjin Medical University Cancer Institute and Hospital from December 2009 to September 2011 were assessed retrospectively. All photos of patients＇ tongue were recorded by the digital camera of uniform type within 1 month after serological examination and regular re-examined by computed tomography （CT）, magnetic resonance imaging and positron emission tomography CT. The presence of sublingual nodules was the positive standard. Chi square test and two-independent-sample test were used to determine the diagnostic value between the status of sublingual nodules and Clinico-pathological characteristics. The optimal cut-off of uric acid （UA） level to diagnose sublingual nodules was determined by receiver operating curve （ROC） analysis. Results： Breast cancer patients with sublingual nodules had a higher risk of recurrence and/or metastasis than patients without it （P〈0.001）. Sublingual nodules was significantly correlated with increased serum UA level （P=0.001）. The optimal cut-off value of UA level to diagnose sublingual nodules was 290 μ mol/L. Furthermore, the elevated serum UA level （ ≥290 μmol/L） was significantly related to breast cancer recurrence and/or metastasis （P〈0.001）. Couclusions： Sublingual nodules were potential diagnostic markers for metastatic breast cancer. The formation of sublingual nodules was associated with elevated level of serum UA.

关键词： breast cancer sublingual nodule metastasis recurrence serum uric acid Chinese medicine diagnosis

TWO-SCALE FEM FOR ELLIPTIC MIXED BOUNDARY VALUE PROBLEMS WITH SMALL PERIODIC COEFFICIENTS

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Journal of Computational Mathematics 2001年第5期19卷 549-560页

作者： Jin-ru Chen Jun-zhi cui School of Mathematics and Computer Sciences Nanjing Normal UniversityNanjing 210097China ICMSEC Academy of Mathematics and Systems SciencesChinese Academy of SciencesBeijing 100080China

Presents a study which proposed a dual approximate expression of the exact solution for mixed boundary value problems of second order elliptic partial differential equation with small periodic coefficients. Dual appro... 详细信息

关键词： two-scale FEM mixed boundary value small periodic coefficients