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The psychological trajectory from diagnosis to approaching end of life in patients undergoing hemodialysis in China: A qualitative study

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International Journal of Nursing Sciences 2017年第1期4卷 29-33页

作者： hong-yan niu Jin-feng Liu RN Blood Purification CentreThe First People's Hospital of ChangzhouChangzhouChina

Background: In China,the number of patients diagnosed with end-stage renal disease has increased rapidly in recent *** undergoing dialysis treatment often experience psychosocial challenges,such as death anxiety,which may potentially cause patients to withdraw from *** nurses and other practitioners who provide direct care to patients undergoing hemodialysis must understand how these challenges are perceived by patients and affect their daily ***: This article investigated the psychological trajectory and life experiences of hemodialysis patients to provide complementary guidance for nurses and healthcare ***: This study utilized a qualitative descriptive phenomenological *** were collected by conducting semistructured interviews and analyzed by content *** were collected through indepth interviews from May to December *** questions were designed to reveal the life experiences and perspectives of hemodialysis *** were selected by convenience sampling approach and recruited from outpatients receiving treatment in a blood-purification center in Jiangsu Province,***: Twenty-three participants were *** stages were extracted from the interview data:(1) afraid stage,(2) adapted stage,and (3) depression ***,three corresponding stages of physiological status were identified: (1) induced stage,(2) stable stage,and (3) severe complications or approaching-end-of-life ***: Patients undergoing dialysis exhibited differing psychological statuses at different physical ***,nurses must assess the psychophysiological symptoms of patients and design individual care plans for each *** studies should focus on developing stage-specific nursing-care protocols.

关键词： Patients undergoing hemodialysis Psychological trajectory Qualitative research

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医学专业英语术语读音的音乐性剖析

医学争鸣 2016年第6期37卷 43-46页

作者：程红平张红艳牛佳刘炜湖北医药学院药护学院湖北十堰442000 湖北医药学院卫生管理与卫生事业发展研究中心湖北十堰442000

医学专业英语术语来源于拉丁语、希腊语。随着社会的进步与发展,其读音虽然变得越来越多,但依然有规律可循。本文着眼于语言的音乐属性来研究医学专业英语术语读音的音乐性,重点论述了医学专业术语的读音和音乐的相关性。为医学科技工... 详细信息

医学专业英语术语来源于拉丁语、希腊语。随着社会的进步与发展,其读音虽然变得越来越多,但依然有规律可循。本文着眼于语言的音乐属性来研究医学专业英语术语读音的音乐性,重点论述了医学专业术语的读音和音乐的相关性。为医学科技工作者、医护人员和在校医学生学习医学专业英语术语提供了语音学方面的理论指导,可以让其在短期内迅速掌握医学英语术语的读音规律。这一规律不仅适合医学科技术语的读音,也适用于广大学科的合成和派生术语的读音。

关键词：医学术语语音音乐性剖析

Enhanced corrosion resistance of epoxy resin coating via addition of CeO_(2) and benzotriazole

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Chinese Journal of Chemical Engineering 2024年第3期67卷 89-96页

作者： Xu Han Ruijie Guo Baolong niu hong yan College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China Key Laboratory of Interface Science and Engineering in Advanced Materials Ministry of EducationTaiyuan University of TechnologyTaiyuan 030024China

The use of fillers to enhance the corrosion protection of epoxy resins has been widely *** this work,cerium dioxide(CeO_(2))and benzotriazole(BTA)were introduced into an epoxy resin to enhance the corrosion resistance of Q235 carbon *** electron microscopy results indicated that the CeO_(2) grains were rod-like and ellipsoidal in shape,and the distribution pattern of BTA was analyzed by energy dispersive *** dynamic potential polarization curve proved the excellent corrosion resistance of the composite epoxy resin with CeO_(2) and BTA co-addition,and electrochemical impedance spectroscopy test analysis indicated the significantly enhanced long-term corrosion protection performance of the composite *** the optimal protective performance was provided by the coating containing 0.3%(mass)CeO_(2) and 20%(mass)BTA,which was attributed to the barrier performance of CeO_(2) particles and the chemical barrier effect of *** formation of corrosion products was analyzed using X-ray *** addition,the corrosion resistance mechanism of the coating was also discussed in detail.

关键词： Benzotriazole Cerium dioxide Corrosion resistance Carbon steel Epoxy resin coating Preparation

C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 pathway as a therapeutic target and regulatory mechanism for spinal cord injury

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Neural Regeneration Research 2025年第8期20卷 2231-2244页

作者： Xiangzi Wang Xiaofei niu Yingkai Wang yang Liu Cheng yang Xuyi Chen Zhongquan Qi School of Medicine Guangxi UniversityNanningGuangxi Zhuang Autonomous RegionChina Graduate School of Tianjin University of Traditional Chinese Medicine TianjinChina Characteristic Medical Center of People’s Armed Police Forces TianjinChina Fujian Maternity and Child Health Hospital FuzhouFujian ProvinceChina

Spinal cord injury involves non-reversible damage to the central nervous system that is characterized by limited regenerative capacity and secondary inflammatory *** expression of the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis exhibits significant differences before and after *** studies have revealed that the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis is closely associated with secondary inflammatory responses and the recruitment of immune cells following spinal cord injury,suggesting that this axis is a novel target and regulatory control point for *** review comprehensively examines the therapeutic strategies targeting the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis,along with the regenerative and repair mechanisms linking the axis to spinal cord ***,we summarize the upstream and downstream inflammatory signaling pathways associated with spinal cord injury and the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 *** review primarily elaborates on therapeutic strategies that target the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis and the latest progress of research on antagonistic drugs,along with the approaches used to exploit new therapeutic targets within the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 axis and the development of targeted ***,there are presently no clinical studies relating to spinal cord injury that are focusing on the C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 *** review aims to provide new ideas and therapeutic strategies for the future treatment of spinal cord injury.

关键词： apoptosis C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 pathway C-C motif chemokine receptor 2 antagonists chemokine ligand 2 chemokine receptor 2 inflammation macrophage microglia spinal cord injury therapeutic method

Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury

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Neural Regeneration Research 2025年第8期20卷 2153-2168页

作者： Xinyu You Lin niu Jiafeng Fu Shining Ge Jiangwei Shi yanjun Zhang Pengwei Zhuang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjinChina Haihe Laboratory of Modern Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina First Teaching Hospital of Tianjin University of Traditional Chinese Medicine TianjinChina National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion TianjinChina

Traumatic brain injury is a prevalent disorder of the central nervous *** addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for patients with traumatic brain injury;however,the underlying pathogenesis remains unclear,and effective intervention methods are *** dysfunction is a significant consequence of traumatic brain *** the most densely innervated peripheral tissue in the body,the gut possesses multiple pathways for the establishment of a bidirectional“brain-gut axis”with the central nervous *** gut harbors a vast microbial community,and alterations of the gut niche contribute to the progression of traumatic brain injury and its unfavorable prognosis through neuronal,hormonal,and immune pathways.A comprehensive understanding of microbiota-mediated peripheral neuroimmunomodulation mechanisms is needed to enhance treatment strategies for traumatic brain injury and its associated *** comprehensively reviewed alterations in the gut microecological environment following traumatic brain injury,with a specific focus on the complex biological processes of peripheral nerves,immunity,and microbes triggered by traumatic brain injury,encompassing autonomic dysfunction,neuroendocrine disturbances,peripheral immunosuppression,increased intestinal barrier permeability,compromised responses of sensory nerves to microorganisms,and potential effector nuclei in the central nervous system influenced by gut ***,we reviewed the mechanisms underlying secondary biological injury and the dynamic pathological responses that occur following injury to enhance our current understanding of how peripheral pathways impact the outcome of patients with traumatic brain *** review aimed to propose a conceptual model for future risk assessment of central nervous system-related diseases while elucidating novel insights into the bidirectional effec

关键词： traumatic brain injury brain-gut-microbiome axis gut microbiota neuroimmune immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry

Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders:drug stability,targeting efficiency,and safety

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Neural Regeneration Research 2025年第7期20卷 1883-1899页

作者： Mingyu Zhang Chunyu Xiang Renrui niu Xiaodong He Wenqi Luo Wanguo Liu Rui Gu Department of Orthopedic Surgery China-Japan Union Hospital of Jilin UniversityChangchunJilin ProvinceChina

Various nanoparticle-based drug delivery systems for the treatment of neurological disorders have been widely ***,their inability to cross the blood–brain barrier hampers the clinical translation of these therapeutic *** are nanoparticles composed of lipid bilayers,which can effectively encapsulate drugs and improve drug delivery across the blood–brain barrier and into brain tissue through their targeting and ***,they can potentially treat traumatic and nontraumatic central nervous system *** this review,we outlined the common properties and preparation methods of liposomes,including thin-film hydration,reverse-phase evaporation,solvent injection techniques,detergent removal methods,and microfluidics ***,we comprehensively discussed the current applications of liposomes in central nervous system diseases,such as Alzheimer's disease,Parkinson's disease,Huntington's disease,amyotrophic lateral sclerosis,traumatic brain injury,spinal cord injury,and brain *** studies related to liposomes are still in the laboratory stage and have not yet entered clinical ***,their application as drug delivery systems in clinical practice faces challenges such as drug stability,targeting efficiency,and ***,we proposed development strategies related to liposomes to further promote their development in neurological disease research.

关键词： Alzheimer's disease amyotrophic lateral sclerosis brain tumors central nervous system Huntington's disease liposome drug delivery neurological disorders Parkinson's disease spinal cord injury traumatic brain injury

Dynamically self-adjustable liquid-liquid and self-adaptive softcontact solid-solid triboelectric nanogenerator for wave energy harvesting

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Nano Research 2025年第1期18卷 404-414页

作者： Yong Long Bingqi Zhao Jianan niu Yuxiu Liu Wei Sha Jiangwen Wang Zhong Lin Wang Weiguo Hu Guangzhou Institute of Blue Energy Knowledge CityHuangpu DistrictGuangzhou 510555China Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 101400China School of Nanoscience and Technology University of Chinese Academy of SciencesBeijing 100049China

Water wave energy exhibits great potential toalleviate the global energy crisis. However, harvesting andutilizing wave energy are challenging due to its irregularity,randomness, and low frequency. Triboelectric nanogenerators(TENGs) have gained significant attention for harvesting waveenergy with high efficiency. This study presents a novelellipsoidal, pendulum-like TENG integrating both liquid-liquid(L-L) and solid-solid (S-S) triboelectricity (LS-TENG). Thisinnovative design enables continuous wave energy harvestingand self-powered marine environment monitoring under variousconditions, including temperature, humidity, and light intensity. The binary immiscible liquids within the LS-TENG’s innersoft balloon create dynamic, and self-adjustable L-L contact interfaces, significantly increasing the L-L contact area andenhancing L-L contact electrification (CE). The unique self-adaptive, soft S-S contact increases the S-S contact areacompared to traditional hard point contact, better adapting to the irregular movements of waves and promoting efficient S-SCE. The LS-TENG achieves highly efficient wave energy harvesting by coupling L-L and S-S CE. Furthermore, the uniquesoft contact design protects the S-S interfaces from mechanical wear and damage during long-term work. The LS-TENG’snovel structure provides an innovative and effective way for water wave energy harvesting.

关键词： self-adaptive soft-contact solid-solid liquid-liquid self-adjustable triboelectric nanogenerator

A new micromechanical approach of micropolar continuum modeling for 2-D periodic cellular material

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Acta Mechanica Sinica 2016年第3期32卷 456-468页

作者： Bin niu Jun yan School of Mechanical Engineering Dalian University of Technology State Key Laboratory of Structural Analysis for Industrial Equipment Department of Engineering Mechanics Dalian University of Technology

In this paper, we present a new united approach to formulate the equivalent micropolar constitutive relation of two-dimensional（2-D） periodic cellular material to capture its non-local properties and to explain the size effects in its structural analysis. The new united approach takes both the displacement compatibility and the equilibrium of forces and moments into consideration, where Taylor series expansion of the displacement and rotation fields and the extended averaging procedure with an explicit enforcement of equilibrium are adopted in the micromechanical analysis of a unit *** numerical examples, the effective micropolar constants obtained in this paper and others derived in the literature are used for the equivalent micropolar continuum simulation of cellular solids. The solutions from the equivalent analysis are compared with the discrete simulation solutions of the cellular solids. It is found that the micropolar constants developed in this paper give satisfying results of equivalent analysis for the periodic cellular material.

关键词： Cellular material Micropolar continuum Size effect Equivalent property

Iterative Learning Control Algorithm with a Fixed Step

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Chinese Journal of Mechanical Engineering 2011年第4期24卷 669-675页

作者： WANG yan niu Jianjun School of Transportation Science and Engineering Beihang University Beijing 100191 China International Petroleum Exploration and Production Corporation China Petroleum ＆ Chemical Corporation Beijing 100083 China

Iterative Learning Control （ILC） captures interests of many scholars because of its capability of high precision control implement without identifying plant mathematical models, and it is widely applied in control engineering. Presently, most ILC algorithms still follow the original ideas of ARIMOTO, in which the iterative-learning-rate is composed by the control error with its derivative and integral values. This kind of algorithms will result in inevitable problems such as huge computation, big storage capacity for algorithm data, and also weak robust. In order to resolve these problems, an improved iterative learning control algorithm with fixed step is proposed here which breaks the primary thought of ARIMOTO. In this algorithm, the control step is set only according to the value of the control error, which could enormously reduce the computation and storage size demanded, also improve the robust of the algorithm by not using the differential coefficient of the iterative learning error. In this paper, the convergence conditions of this proposed fixed step iterative learning algorithm is theoretically analyzed and testified. Then the algorithm is tested through simulation researches on a time-variant object with randomly set disturbance through calculation of step threshold value, algorithm robustness testing,and evaluation of the relation between convergence speed and step size. Finally the algorithm is validated on a valve-serving-cylinder system of a joint robot with time-variant parameters. Experiment results demonstrate the stability of the algorithm and also the relationship between step value and convergence rate. Both simulation and experiment testify the feasibility and validity of the new algorithm proposed here. And it is worth to noticing that this algorithm is simple but with strong robust after improvements, which provides new ideas to the research of iterative learning control algorithms.

关键词： iterative learning control fixed step time variant system simulating study robot control