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ROS-degradable polythioketal urethane scaffold for porcine wound repair

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Acta Pharmaceutica Sinica B 2024年第10期14卷 4628-4631页

作者： Salim Ullah hong-tao xu Jianliang Shen The Fifth Affiliated Hospital of Wenzhou Medical University Lishui 323020China National Engineering Research Center of Ophthalmology and Optometry Eye HospitalWenzhou Medical UniversityWenzhou 325027China Zhejiang Engineering Research Center for Tissue Repair Materials Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhou 325001China

Porous,resorbable synthetic biomaterials such as polyesters provide a cost-effective framework for the healing of skin ***,it must be optimized to reduce acidic breakdown and improve immunological and regenerative ***,Craig ***^(1) and his team published his work in Science Translational Medicine,which delineates the synthesis,characterization,and application of ethylene glycol(EG7)polythioketal urethane(PTK-UR).Here,they integrate seven ethylene glycol repeats unites in the PTK-UR polymer backbone to enhance its hydrophilicity and biological compatibility,facilitating optimal wound-healing processes in porcine skin *** implants promote extracellular matrix(ECM)deposition,reepithelialization,and remodeling while effectively transitioning to a healing phenotype from a moderate inflammatory response.

关键词： (ROS)-degradable polythioketal Hydrophilicity Antioxidant Extracellular matrix deposition Ischemic wound healing

Asymmetric catalyzed intramolecular aza-Michael reaction mediated by quinine-derived primary amines

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Chinese Chemical Letters 2017年第8期28卷 1793-1797页

作者： Xian-Dong Zhai Zhong-Duo Yang Zhi Luo hong-tao xu School of Life Science and Engineering Lanzhou University of Technology Shanghai Institute of Materia Medica Chinese Academy of Sciences

An intramolecular organocatalytic enantioselective aza-Michael reaction of carbamates, sulfonamides and acetamides to a,b-unsaturated ketones was developed. This process is promoted by 9-amino-9-deoxy-epi-quinine and diphenyl hydrogen phosphate to afford a straightforward and expeditious synthesis of several synthetically useful five-and six-membered heterocycles with excellent enantioselectivity（92%–97.5% ee） and very good yields（up to 99%）.

关键词： Asymmetric catalysis Intramolecular aza-Michael reaction Primary amine Five-and six-membered heterocycles Pyrrolidine and piperidine Enantioselective organocatalytic

Transformation of Structure and Properties of Vesicles Induced by Transition Metal Ions

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Chinese Chemical Letters 2005年第12期16卷 1667-1670页

作者： hong tao GUO Fei xu Xiao Hai ZHOU Jin Feng DONG Gao Yong ZHANG Xin Lin hong College of Chemistry and Molecular Sciences Wuhan University Wuhan 430072

This paper proved that octodecyl propylenediamine could form vesicles in pure water and aqueous solution of CuCl2 or Cu（NO3）2. The structure and morphology of vesicles were different when the copper （Ⅱ） salt was added to the solution. The results showed that both the counterions and the ligands had strong influence on the configuration of coordinated structures and packing model in bilayer membrane of vesicles.

关键词： Octodecyl propylenediamine copper (Ⅱ) ions vesicle bilayer membrane counterions coordinated structure

The Role of Calcium in Mediating SlIAAs Expression in Tomato Pedicel Explants

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Agricultural Sciences in China 2010年第7期9卷 980-984页

作者： ZUO Xian-hong xu tao QI Ming-fang LU Shuang-shuang LI Jin-hong LI hong GAO Song LI Tian-lai Key Laboratory of Protected Horticulture of Liaoning Province/College of Horticulture Shenyang Agricultural University Shenyang 110161 P.R. China

In order to illuminate the effect of calcium on the IAA signal transduction,we studied the expression of eight SlIAA genes which were up-regulated by calcium during the abscission after short-term（1 h） and long-term（16 h） treatments with calcium,IAA and calcium *** results indicated that calcium induced SlIAAs expression in 1 h at low concentration,EGTA affected little SlIAAs expression;it also increased IAA-induced transcript level of SlIAAs,TFP（named trifluoperazine） decreased most SlIAAs expression below the level of calcium combined with IAA-induced expression,except for ***-term treatment of calcium or calcium inhibitors suppressed some SlIAAs expression,whereas TFP enhanced all SlIAAs ***,SlIAA29 was induced by most treatments excluding 16 h EGTA.

关键词： tomato calcium IAA calcium inhibitors SIlAA gene

Silicon on Insulator with Highly Uniform Top Si Fabricated by H/He Coimplantation

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Chinese Physics Letters 2019年第6期36卷 103-106页

作者： Xin Su Nan Gao Meng Chen hong-tao xu Xing Wei Zeng-Feng Di State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences University of Chinese Academy of Sciences Shanghai Simgui Technology Co. Ltd.

Silicon on insulator with highly uniform top Si is fabricated by co-implantation of H+and He+ions. Compared with the conventional ion-slicing process with H implantation only, the co-implanted specimens whose He depth is deeper than H profile have the top Si layer with better uniformity after splitting. In addition, the splitting occurs at the position that the maximum concentration peak of H overlaps with the secondary concentration peak of He after annealing. It is suggested that the H/He co-implantation technology is a promising approach for fabricating fully depleted silicon on insulator.

关键词： Silicon on Insulator H/He Coimplantation secondary concentration peak

Weathering Characteristics of Sloping Fields in the Three Gorges Reservoir Area, China

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Pedosphere 2006年第1期16卷 50-55页

作者： JIANG hong-tao xu Fei-Fei CAI Yi YANG Da-Yuan Department of Urban and Resources Science Nanjing University Nanjing 210093 （China）. Department of Earth Science Nanjing University Nanjing 210093 （China）

For the purpose of understanding the weathering characteristics of surface layers in purple mudstone sloping fields of the Three Gorges Reservoir area of China, oxide content of major elements, composition of clay minerals, magnetic susceptibility, and difference in weathering characteristics of surface layers under different slope gradients were determined. The results showed that the oxide content of Si, Al, and Fe ranged from 60% to 75% and the weathering coefficient with depth showed no trend along the slope gradient. Also, for gentle (10° and 15°) and intermediate (25° and 40°) slopes the clay relative diffraction peak for kaolinite at the surface between 0-10 cm and 10-20 cm declined with an increase in slope gradient, while the relative diffraction peak for kaolinite in weathered layers on steep slopes (50° and 60°) disappeared altogether. Magnetic susceptibility decreased with increasing depth and, for a given depth layer, decreased with an increase in slope gradient. Analysis of the oxide content, weathering coefficients, clay minerals, and magnetic susceptibility showed that in the Three Gorges Reservoir area, the pedogenesis of the weathering layer in purple mudstone sloping fields was weak with weaker soil formation going from gentle slope to steep slope.

关键词： purple mudstone sloping field Three Gorges weathering

Primary pulmonary meningioma and minute pulmonary meningothelial-like nodules: Rare pulmonary nodular lesions requiring more awareness in clinical practice

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World Journal of Clinical Cases 2024年第11期12卷 1857-1862页

作者： Li-Dan Liu Ke-Xin Zhang Hai-Ning Zhang Yi-Wen Zheng hong-tao xu Department of Pathology The First Hospital and College of Basic Medical Sciences of China Medical UniversityShenyang 110001Liaoning ProvinceChina

In this editorial,we comment on an article by Ruan et al published in a recent issue of the World Journal of Clinical *** meningothelial proliferative lesions,including primary pulmonary meningiomas,minute pulmonary meningothelial-like nodules,and metastatic pulmonary meningiomas are rare pulmonary *** lesions are difficult to differentiate from lung cancers based on clinical and imaging ***,we briefly introduce the clinical,imaging,and pathological characteristics of these lesions and discuss their pathogenesis to strengthen the current understanding of pulmonary meningothelial proliferative lesions in clinical diagnosis and therapy.

关键词： Pulmonary meningothelial proliferation Primary pulmonary meningioma Minute pulmonary meningothelial-like nodule Lung neoplasm Rare pulmonary nodular lesion

Thymic lipofibroadenomas:Three case reports

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World Journal of Clinical Cases 2023年第1期11卷 164-171页

作者： Mai-Qing Yang Zhi-Qiang Wang Li-Qian Chen Su-Mei Gao Xing-Ning Fu Hai-Ning Zhang Ke-Xin Zhang hong-tao xu Department of Pathology Weifang People's Hospital(First Affiliated Hospital of Weifang Medical University)Weifang 261041Shandong ProvinceChina Department of Orthopedics and Trauma Weifang People's Hospital(First Affiliated Hospital of Weifang Medical University)Weifang 261041Shandong ProvinceChina Department of Pathology The First Hospital and College of Basic Medical Sciences of China Medical UniversityShenyang 110001Liaoning ProvinceChina

BACKGROUND Thymic lipofibroadenomas are extremely *** this study,we investigated the clinicopathological characteristics of thymic *** SUMMARY This study included three patients with thymic *** retrospectively analyzed the patient data to determine the clinicopathological characteristics of thymic *** study included one man and two women[mean age,43(33–59)years].All patients were non-smokers and presented with well-defined anterior mediastinal *** cut surfaces of the tumors were solid,with a mixture of yellow and white *** evaluation of resected specimens showed scattered cord-like structures of epithelial cells embedded within abundant fibrotic and hyaline stroma admixed with variable quantities of adipose *** patient showed hyperplastic thymic tissue in a part of the *** Thymic lipofibroadenomas are an extremely rare type of benign thymic *** removal of lipofibroadenomas is usually curative.

关键词： Lipofibroadenoma Thymoma Rare thymic tumor Clinicopathological characteristics Thoracic tumor Case report

Bio-electronic bandage: Self-powered performances to accelerate intestinal wound healing

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Chinese Chemical Letters 2024年第12期35卷 1-3页

Intestinal wound healing is complex because of the intestine's intricate structure and the environment, which contains its microbes and digestive modules. Traditional suturing is the utmost standard surgical methodology, which can imply hyperplasia and obstruction, two probable harmful consequences. Thus, patients often face a delayed healing time and constrained healing experiences.

关键词： healing wound intestine