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T-2 toxin-induced apoptosis involving Fas,p53,Bcl-xL,Bcl-2,Bax and caspase-3 signaling pathways in human chondrocytes

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第6期9卷 455-463页

作者： Jing-hong CHEN Jun-ling CAO Yong-lie CHU Zhi-lun wang Zhan-tian YANG hong-lin wang Ministry of Education Key Laboratory of Environment and Genes related to Diseases Institute of Endemic Diseases School of Medicine Xi ＇an Jiaotong University Xi ＇an 710061 China

Objective:To investigate the effects of T-2 toxin on expressions of Fas,p53,Bcl-xL,Bcl-2,Bax and caspase-3 on human ***:Human chondrocytes were treated with T-2 toxin(1～20 ng/ml)for 5 ***,p53 and other apoptosis-related proteins such as Bax,Bcl-2,Bcl-xL,caspase-3 were determined by Western blot analysis and their mRNA expressions were determined by reverse transcriptase-polymerase chain reaction(RT-PCR).Results:Increases in Fas,p53 and the pro-apoptotic factor Bax protein and mRNA expressions and a decrease of the anti-apoptotic factor Bcl-xL were observed in a dose-dependent manner after exposures to 1～20 ng/ml T-2 toxin,while the expression of the anti-apoptotic factor Bcl-2 was ***,T-2 toxin could also up-regulate the expressions of both pro-caspase-3 and caspase-3 in a dose-dependent ***:These data suggest a possible underlying molecular mechanism for T-2 toxin to induce the apoptosis sig- naling pathway in human chondrocytes by regulation of apoptosis-related proteins.

关键词： Apoptosis Apoptosis-related proteins Chondrocyte T-2 toxin

Facile Synthesis of Long,Straight and Uniform Copper Nanowires via a Solvothermal Method

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稀有金属材料与工程 2006年第A03期35卷 644-645页

作者： Chunfu lin hong lin Ning wang Xing Zhang Jun Yang Jianbo Li Xiaozhan Yang State Key Lab of New Ceramics ＆ Fine Processing Department of Materials Science ＆ Engineering Tsinghua University Beijing 100084 China

Copper nanowires were facilely prepared via a solvothermal *** this method,cetyitrimethylammonium bromide (CTAB) was used as a soft template,copper nitrate was an inorganic precursor,and absolute ethanol served as a reducing agent as well as a solvent.X-ray diffraction (XRD) and scanning electron microscopy (SEM) were used to characterize the as-prepared copper *** as-prepared copper nanowires are fairly uniform and *** majority of them are longer than 100μm and some even longer than 200μ***,most nanowires are quite *** addition, The mechanism of the growth process of copper nanowires was discussed.

关键词： copper nanowires solvothermal method template

Fabrication of Porous Nanocrystalline NiCo_2O_4 Electrode for Water Electrolysis

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稀有金属材料与工程 2006年第A03期35卷 646-647页

作者： Jun Yang Xiaozhan Yang Jianbao Li hong lin Ning wang Chunfu lin Gangfeng Guo State Key Lab of New Ceramics ＆ Fine Processing Department of Materials Science ＆ Engineering Tsinghua University Beijing 100084 China

A porous nanocrystalline NiCo_2O_4 compound electrode was *** morphology of the electrode was controlled by altering the concentration of precipitant (NaOH solution).The electrode was consisted of metal substrate (Ni) and porous nanocrystalline NiCo_2O_4 film which was stacked by homosized and pretty regular hexagonal nanoparticles,with thinner than 50 nm and about 200 nm in *** electrode exhibits good electrochemical properties compared with Ni electrode.

关键词： electrophoretic deposition nanocrystalline NiCo2O4 porous water electrolysis

On the Station-Keeping and Control of the World Space Observatory/Ultraviolet

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Chinese Journal of Astronomy and Astrophysics 2006年第3期6卷 372-378页

作者： Xi-Yun Hou Hai-hong wang lin Liu Department of Astronomy Nanjing University Nanjing 210093 Institute of Space Enviromnent and Astronautics Nanjing University Nanjing 210093

Collinear libration points play an important role in deep space exploration because of their special positions and dynamical characteristics. Since motion around them is unstable, we need to control the spacecraft if we wish to keep them around such a libration point for a long time. Here we propose a continuous low-thrust control strategy, illustrated with numerical simulations combined with the orbit design and control of the World Space Observatory/UltraViolet （WSO/UV）.

关键词： celestial mechanics - WSO/UV - low thrust

One pot cascade synthesis of substituted 1,2,4-triazol-3-ones

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Chinese Science Bulletin 2010年第25期55卷 2879-2884页

作者： SU YeHua JIANG Zhen hong Deng lin XianFu wang YanGuang Department of Chemistry Zhejiang University Hangzhou 310027 China

Substituted triazolinones were prepared by a three-component reaction of aldehydes,hydrazines and azodicarboxylates using TFA as a catalyst. The procedure was convenient and efficient,utilizing readily available subst... 详细信息

关键词：级联过程合成三唑反式脂肪酸锅催化剂三组分醛

Feeding methods, sleep arrangement, and infant sleep patterns: a Chinese population-based study

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World Journal of Pediatrics 2016年第1期12卷 66-75页

作者： Xiao-Na Huang Hui-Shan wang Jen-Jen Chang lin-hong wang Xi-Cheng Liu Jing-Xiong Jiang lin An Department of Children Health National Center for Maternal and Children HealthChinese Center for Disease Control and PreventionBeijingChina Department of Epidemiology Saint Louis University College for Public Health and Social JusticeSt.Louis.MOUSA The National Center for Chronic and Non-communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Bronchoscopy Center Affi liated Children Hospital of Beijing Capital Medical UniversityBeijingChina Department of Public Health Peking University Health Science CenterBeijingChina

Background:Findings from prior research into the effect of feeding methods on infant sleep are *** objectives of this study were to examine infants'sleep patterns by feeding methods and sleep arrangement from birth to eight months ***:This longitudinal cohort study enrolled 524 pregnant women at 34-41 weeks of gestation and their infants after delivery in 2006 and followed up until eight months *** study subjects were recruited from nine women and children hospitals in nine cities in China(Beijing,Chongqing,Wuhan,Changsha,Nanning,Xiamen,Xi'an,Jinan,and Hailin).Participating infants were followed up weekly during the first month and monthly from the second to the eighth month after ***-four hour sleep diaries recording infants'sleeping and feeding methods were administered based on caregiver's *** mixed growth curve models were fi tted to estimate the effects of feeding methods and sleep arrangement on infants'sleep patterns over time,controlling for maternal and paternal age,maternal and paternal education level,household income,supplementation of complementary food,and infant birth weight and ***:Exclusively formula fed infants had the greatest sleep percentage/24 h,followed by exclusively breast milk fed infants and partially breast milk fed infants(P<0.01).Night waking followed a similar ***,the differences in sleep percentage and night waking frequency between exclusively formula and exclusively breast milk fed infants weakened over time as infants *** addition,compared to infants with bed-sharing sleep arrangement,those with room sharing sleep arrangement had greater daytime and 24-hour infant sleep percentage,whereas those with sleeping alone sleep arrangement had greater nighttime sleep ***:Our data based on caregiver's selfreport suggested that partial breastfeeding and bedsharing may be associated with less sleep in *** care professio

关键词： breast feeding feeding method infant sleep sleep arrangement

Sliding-cupping along meridian for lymphedema after breast cancer surgery: A randomized controlled trial

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World Journal of Acupuncture-Moxibustion 2019年第3期29卷 179-185页

作者： Zhi-feng XIONG Ting wang hong-lin wang Yong-yue wang lin GAN Gang Lv Breast Thyroid Department of Chongqing Traditional Chinese Medicine Hospital Chongqing 400021China

Objective:To observe the clinical efficacy difference between sliding-cupping along meridian combined with short-stretch elastic bandage wrapping and comprehensive detumescence therapy in treating lymphedema after breast cancer ***:Sixty patients with lymphedema after breast cancer surgery were randomly divided into the sliding-cupping group and the comprehensive detumescence therapy(CDT)group,with 30 cases in each *** sliding-cupping group used the sliding-cupping along meridian therapy,and the sliding-cupping was applied along the three yin meridians and three yang meridians on the hand of the affected-side upper limbs,continuing for 25-30 *** the sliding-cupping was finished,the affected limb was wrapped with the short-stretch elastic *** CDT group was treated with comprehensive detumescence therapy(CDT).Both groups were treated once a day,with14 times as one course of treatment,and there was totally 1 course of *** changes of circumferences before and after treatment of the affected limb were measured by a flexible ruler,and the efficacy was *** subcutaneous tissue thickness and the full skin layer thickness of the patients with moderate to severe edema in sliding-cupping group were measured by color Doppler ***:After treatment,the circumferences at the cubital crease,5 cm above olecranon,and 10 cm above the olecranon of the affected limbs in the sliding-cupping group were(26.02±2.42)cm,(28.43±3.13)cm,and(30.05±2.80)cm respectively,which were all reduced compared with the pre-treatment circumference(27.95±3.00)cm,(30.80±3.38)cm,and(32.17±2.96 cm).In the sliding-cupping group,the post-treatment subcutaneous tissue thicknesses at 5 cm above the olecranon,10 cm above the olecranon and 5 cm below the olecranon,and full skin layer thickness at 10 cm below the olecranon of the 15 patients with moderate to severe edema were(8.71±2.83)cm,(8.53±2.4)cm,(6.46±1.38)cm,and(1.61±0.17)cm respectively,which were a

关键词： Sliding-cupping Along meridian Postoperative breast cancer surgery Lymphedema Randomized controlled trial

Modified membrane fixation technique in a severe continuous horizontal bone defect:A case report

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World Journal of Clinical Cases 2022年第17期10卷 5789-5797页

作者： lin-hong wang Yan Ruan Wen-Yan Zhao Jian-Ping Chen Fan Yang Center for Plastic and Reconstructive Surgery Department of StomatologyZhejiang Provincial People's Hospital(Affiliated People's HospitalHangzhou Medical College)Hangzhou 310014Zhejiang ProvinceChina Graduate Department Bengbu Medical CollegeBengbu 233030Anhui ProvinceChina Department of Stomatology The First People's Hospital of Hangzhou Lin'an DistrictHangzhou 311399Zhejiang ProvinceChina

BACKGROUND Continuous severe horizontal bone defect is common in the aesthetic maxillary anterior area,and presents a major challenge in implant dentistry and requires predictable bone augmentation to increase the width of the alveolar *** SUMMARY A 24-year-old man,with a history of well-controlled IgA nephropathy,presented to the Dentistry Department of our hospital complaining of missing his right maxillary anterior teeth 1 mo *** horizontal alveolar bone defects at sites of teeth 12,13 and 14 were diagnosed.A modified guided bone regeneration surgical approach stabilizing the absorbable collagen membrane and particulate graft materials by periosteal diagonal mattress suture(PDMS)combined with four corner pins was used for this severe continuous horizontal bone *** outcome revealed that the newly formed alveolar ridge dimension increased from 0.72 mm to 11.55 mm horizontally 10 mo postoperatively,with no adverse *** implant surgery was successfully *** This case highlights that PDMS combined with four corner pins is feasible to maintain the space and stabilize the graft and membranes in severe continuous horizontal bone defect.

关键词： Horizontal bone defect Guided bone regeneration Periosteal diagonal mattress suture Pin Case report

Variable Stars in the 50BiN Open Cluster Survey.Ⅲ.NGC 884

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Research in Astronomy and Astrophysics 2024年第2期24卷 36-45页

作者： lin-hong wang Qian-Heng Nie Kun wang Xiao-Dian Chen Chun-Guang Zhang Li-Cai Deng Xiao-Bin Zhang Tian-Lu Chen Department of Physics College of ScienceTibet UniversityLhasa 850000China Key Laboratory of Cosmic Rays Tibet UniversityMinistry of EducationLhasa 850000China Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China Middlesex School ConcordMassachusettsUnited States of America School of Physics and Astronomy China West Normal UniversityNanchong 637002China

Open clusters are the basic building blocks that serve as a laboratory for the study of young stellar populations in the Milky *** stars in open clusters provide a unique way to accurately probe the internal structure,temporal and dynamical evolutionary stages of individual stars and the host *** most powerful tool for such studies is time-domain photometric *** paper follows the route of our previous work,concentrating on a photometric search for variable stars in NGC *** target cluster is the companion of NGC869,forming the well-known double cluster system that is gravitationally *** the observation run in 2016 November,a total of 9247 B-band CCD images and 8218Ⅴ-band CCD images were *** detected a total of 15 stars with variability in visual brightness,including five Be stars,three eclipsing binaries,and seven of unknown *** new variable stars were discovered in this *** also compared the variable star content of NGC 884 with its companion NGC 869.

关键词： stars variables general-(Galaxy:)open clusters and associations individual(…,…)-(stars:)binaries general