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Comparison of updated birth weight,length and head circumference charts by gestational age in China with the INTERGROWTH-21 st NCSS charts:a population-based study

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World Journal of Pediatrics 2023年第1期19卷 96-105页

作者： Ya-Qin Zhang Hui Li Xin-Nan Zong hua-hong wu Department of Growth and Development Capital Institute of PediatricsNo.2Ya Bao RoadChaoyang DistrictBeijingChina

Background INTERGROWTH-21 st Newborn Cross-Sectional Study(NCSS)charts were established and recommended for global ***,whether one international reference is appropriate for all populations is still *** aim to compare the updated Chinese birth size charts by gestational age with INTERGROWTH-21st NCSS *** A cross-sectional survey was carried out,and the birth weight,length and head circumference of 24,375 infants born after uncomplicated pregnancies at gestational age ranging from 24+0 to 42+6 weeks were measured in 13 cities in China from 2015 to *** charts were *** measurements of all these infants were evaluated by the methods of calculating their Z scores using the INTERGROWTH-21 st *** prevalence of small for gestational age(SGA)and large for gestational age(LGA)based on birth weight was analyzed using Chinese charts and INTERGROWTH-21st *** The mean Z scores were 0.10 for birth weight,0.35 for length and-0.02 for head *** to the INTERGROWTH-21st charts,the Chinese birth weight percentile curves were higher except for the 90th percentile at 29-37 weeks gestational age,and the length percentile curves were higher after 33 weeks gestational age,while the 10th percentile of the head circumference was lower and the other percentiles were *** prevalence of SGA was 10.1%[95%confidence interval(CI)=9.7%-10.5%]using the Chinese birth weight chart and 6.5%(95%CI=6.2%-6.8%)using the INTERGROWTH-21 st birth weight *** prevalence of LGA was 9.9%(95%CI=9.5%-10.2%)and 8.2%(95%CI=7.9%-8.6%)using the Chinese and INTERGROWTH-21st birth weight charts,*** Chinese birth size charts based on infants born after uncomplicated pregnancies were different from the INTER-GROWTH-21st *** in the classification of newborns by the two charts should receive attention,and whether the application of INTERGROWTH-21st in Chinese newborns will lead to miscl

关键词： Birth length Birth weight Growth charts Head circumference Newborns

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Changes of feeding patterns in Chinese city children under 2 years from 1985 to 2015: results from a series of national cross-sectional surveys

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World Journal of Pediatrics 2019年第2期15卷 176-181页

作者： hua-hong wu Ya-Qin Zhang Xin-Nan Zong Hui Li Department of Growth and Development Capital Institute of PediatricsYaBao RoadChaoYang DistrictBeijing 100020China

Background In China,as the social transformation and economic development from 1985 to 2015,children's feeding pattern has undergone some *** we aimed to analyze the secular trend on feeding patterns of city children in *** All data were from a series of national survey which implemented once every 10 years in China from 1985 to *** use same indexes to evaluate the feeding pattern of children in these four *** From 1985 to 2005,the exclusive breastfeeding rates in infants under 6 months of age decreased,especially in suburban areas decreased by 17.7%;the continuous breastfeeding rate of 1-year-old children in suburban area decreased from 60.1 to 27.6%.However,from 2005 to 2015,the exclusive breastfeeding rates under 6 months of age increased by 16.0% in urban areas and 5.9% in suburban areas;the continuous breastfeeding rate of 1-year-old children in urban increased from 17.0 to 36.0%.The overall feeding rate of complementary food in infants under 6 months of age declined from 1985 to 2015;the average age at introduction of all complementary foods was around 6 months of age in *** There is an obvious trend on feeding pattern of Chinese *** 1985 to 2005,the breastfeeding rate decreased,the duration time of breastfeeding was shortened and the age at introduction of complementary food was *** 2005 to 2015,the breastfeeding rate increased,the duration time of breastfeeding was prolonged,and the age at introduction of complementary food was postponed.

关键词： Breastfeeding Complementary feeding Infant and young children Secular change

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ROLE OF B LYMPHOCYTE AND ITS SUBPOPULATIONS IN PATHOGENESIS OF IMMUNORELATED PANCYTOPENIA

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Chinese Medical Sciences Journal 2007年第3期22卷 199-202页

作者： Rong Fu Zong-hong Shao hong Liu Yu-hong wu hua-quan Wang Li-min Xing Department of Hematology and Oncology General Hospital of Tianjin Medical University Tianjin 300052

Objective To measure the quantities and apoptosis-related protein levels of B lymphocyte in the patients with immunorelated pancytopenia （IRP） and explore the action of B lymphocyte in the pathogenic mechanism of IRP. Methods Quantifies of whole B lymphocytes and CD5^＋ B lymphocytes as well as the expressions of Fas and Bcl-2 in B lymphocytes in 35 patients with untreated IRP, 15 IRP patients in complete remission （CR）, and 10 normal controls were assayed by flow cytometry. The percentages of B lymphocyte and CD5^＋ B lymphocyte were significantly higher in untreated IRP patients than in CR IRP patients and normal controls （ P 〈 0. 05 ）, and there was no significant difference between the latter two groups （ P 〉 0. 05 ）. There was no significant difference of Fas expression in B lymphocyte among three groups （ P 〉 0. 05）. The expression of Bcl-2 in B lymphocyte was significantly higher in untreated patients than in CR patients or normal controls （ P 〈 0. 01 ）, and significantly higher in CR patients than in normal controls （ P 〈 0. 01 ）. The apoptosis. related index was significantly lower in untreated patients than in CR patients or normal controls （ P 〈 0. 05 ）, and signif. icantly lower in CR patients than in normal controls （ P 〈 0. 05 ）. The percentage of B lymphocyte was positively correlated with post-treated response time （ r = 0. 53, P 〈 0. 01 ）. Conclusion The production of auto-antibodies in IRP patients probably has some relationship with the abnormal quantifies of B lymphocyte and its subpopulations as well as with the inhibition of B lymphocyte apoptosis.

关键词： immunorelated pancytopenia B lymphocyte quantifies apoptosis

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Phytochemical and pharmacological studies on Solanum lyratum:a review

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Natural Products and Bioprospecting 2022年第1期12卷 600-634页

作者： Yue Zhao Wen-Ke Gao Xiang-Dong Wang Li-hua Zhang Hai-Yang Yu hong-hua wu State Key Laboratory of Component-Based Chinese Medicine Institute of Traditional Chinese MedicineTianjin University of Traditional Chinese Medicine10 Poyanghu RoadWest AreaTuanbo New TownJinghai DistrictTianjin 301617People’s Republic of China

Solanum lyratum is one of the temperate plants,broadly distributed in Korea,China,Japan,India,and South-East Asia and well-documented in those oriental ethnic medicine systems for curing cancers,jaundice,edema,gonorrhea,cholecystitis,phlogosis,rheumatoid arthritis,*** review systematically summarized the research progress on *** respecting the botany,traditional uses,phytochemistry,pharmacology,and toxicology to increase people’s in-depth understanding of this plant,by data retrieval in a series of online or off-line electronic databases as far as we can *** saponins and alkaloids,terpenoids,nitrogenous compounds,and flavonoid compounds are the main chemical constituents in *** them,steroidal alkaloids and saponins are the major active ingredi-ents ever found in ***,exerting activities of anti-cancer,anti-inflammation,anti-microbial,anti-allergy,and anti-oxidation in vivo or in *** a result,*** has been frequently prescribed for the abovementioned therapeutic purposes,and there are substantial traditional and modern shreds of evidence of its use.

关键词： Solanum lyratum Thunb. Steroidal saponins Steroidal alkaloids Anti-cancer Toxicity

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Profiling of Differentially Expressed Genes in LRRC4 Overexpressed Glioblastoma Cells by cDNA Array

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Acta Biochimica et Biophysica Sinica 2005年第10期37卷 680-687页

作者： Qiu-hong ZHANG Ming-hua wu Li-Li WANG Li CAO Ke TANG Cong PENG Kai GAN Xiao-Ling LI Gui-YuanLI Cancer Research Institute,Central South University,Changsha 410078, China Cancer Research Institute Central South UniversityChangsha 410078 China

Our previous study has shown that LRRC4 is a novel member of the leucine-rich repeat (LRR)superfamily and has the potential to suppress brain tumor *** order to further analyze the functionsof LRRC4 on the maintenance of normal function and suppression of tumorigenesis in the central nervoussystem,we investigated alterations in gene expression related to neurobiology by the Atlas array in twoinducible dual-stable LRRC4-overexpressing cell *** of 588 genes spotted on the Atlas membraneshowed altered expression levels in LRRC4 transfected U251MG Tet-on cells,which are involved in cellproliferation and cell cycle progression,tumor invasion and metastasis,and neurotransmitter synthesis *** addition,cell invasion assay results showed that LRRC4 can inhibit the U251MG cell *** studies represent the first cDNA array analysis of the effects of LRRC4 on the involvement ofdifferent neurobiological genes in U251MG glioblastoma cells and provide new insights into the function ofLRRC4 in glioma.

关键词： differential expression leucine-rich repeat LRRC4 glioma cDNA microarray

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Distribution characteristics and environmental risk assessment following metal(loid)s pollution incidents at Southwest China mining site

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Transactions of Nonferrous Metals Society of China 2022年第12期32卷 4062-4075页

作者： Zhen-xing WANG Yun-jun YU Tian-tian YE Jiang-chi FEI Xin-yu SONG Jian-wei PENG Yao-yu ZHOU hong-hua wu South China Institute of Environmental Sciences Ministry of Ecology and EnvironmentGuangzhou 510530China State Environmental Protection Key Laboratory of Water Environmental Simulation and Pollution Control Guangzhou 510655China College of Resources and Environment Hunan Agricultural UniversityChangsha 410128China Guangxi Hezhou Dongrong Industrial Investment Group Co. Ltd.Hezhou 542899China

Limited information is available on long-term effects of metal(loid)s pollution incidents. Here, we analyze the distribution characteristics and quantification of elements in the Southwest China Keda mining site, which is one of the most populated sites and enables human health and ecological risk assessments of elemental pollution. The results on modified degree of contamination indicated that the soil and sediment were highly contaminated near Dahu *** health risk of children was almost 2.5 times that of adults in surface water, and 7.1 times in soil, ***, Tl and As were the main health risk contributors in surface water and soil, respectively, and As posed the highest ecological risk both in soil and sediment. These results indicated the potential impact of toxic metal(loid)s on the health of residents and environment. Hence, more scientific attention and proper management need to be paid to this environmental challenge in the future.

关键词： thallium arsenic mining site ecological risk health risk

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鑫朋滑坡失稳影响因素分析及比较

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煤炭技术 2021年第3期40卷 70-73页

作者：闵迪洪五华贵州省煤田地质局水源队贵阳550081

在野外调查的基础上,结合滑坡基本地质环境条件,借助Geostudio分析比较加载与降雨两大灾害影响因素作用强度,并确定鑫朋滑坡相应的破坏模式。研究结果表明:鑫朋滑坡灾害影响因素中坡体后缘加载的作用大于降雨。持续降雨,滑坡位移场、剪... 详细信息

在野外调查的基础上,结合滑坡基本地质环境条件,借助Geostudio分析比较加载与降雨两大灾害影响因素作用强度,并确定鑫朋滑坡相应的破坏模式。研究结果表明:鑫朋滑坡灾害影响因素中坡体后缘加载的作用大于降雨。持续降雨,滑坡位移场、剪应变场、渗流场具有极强相似性,堆载体率先发生滑移,继而牵引第四系地层发生浅层蠕滑变形。

关键词：地质环境加载降雨破坏模式灾害影响因素

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Advancements and Challenges in Organic–Inorganic Composite Solid Electrolytes for All‑Solid‑State Lithium Batteries

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Nano-Micro Letters 2025年第1期17卷 46-97页

作者： Xueyan Zhang Shichao Cheng Chuankai Fu Geping Yin Liguang Wang Yongmin wu hua Huo State Key Laboratory of Space Power‑Sources School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001People’s Republic of China College of Chemical and Biological Engineering Zhejiang UniversityHangzhou 310058People’s Republic of China State Key Laboratory of Space Power-Sources 2965 Dongchuan RoadMinhang DistrictShanghai 200240People’s Republic of China

To address the limitations of contemporary lithium-ion batteries,particularly their low energy density and safety concerns,all-solid-state lithium batteries equipped with solid-state electrolytes have been identified as an up-and-coming *** the various SEs,organic–inorganic composite solid electrolytes(OICSEs)that combine the advantages of both polymer and inorganic materials demonstrate promising potential for large-scale ***,OICSEs still face many challenges in practical applications,such as low ionic conductivity and poor interfacial stability,which severely limit their *** review provides a comprehensive overview of recent research advancements in ***,the influence of inorganic fillers on the main functional parameters of OICSEs,including ionic conductivity,Li+transfer number,mechanical strength,electrochemical stability,electronic conductivity,and thermal stability are systematically *** lithium-ion conduction mechanism of OICSE is thoroughly analyzed and concluded from the microscopic ***,the classic inorganic filler types,including both inert and active fillers,are categorized with special emphasis on the relationship between inorganic filler structure design and the electrochemical performance of ***,the advanced characterization techniques relevant to OICSEs are summarized,and the challenges and perspectives on the future development of OICSEs are also highlighted for constructing superior ASSLBs.

关键词： Composite solid electrolytes Inorganic filler Interfacial stability Li-ion conduction mechanism Characterization techniques

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木薯淀粉对猪肉盐溶蛋白凝胶特性的影响

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现代食品科技 2016年第11期32卷 123-127,55页

作者：栗俊广蒋爱民白艳红张华吴月郑州轻工业学院食品与生物工程学院河南郑州450000 华南农业大学食品学院广东广州510640

研究了添加木薯淀粉对猪肉盐溶蛋白凝胶功能特性的影响。用质构仪、流变仪和离心法测定了凝胶质构、动态流变和保水性的变化,用低场核磁共振仪和扫描电镜分析了凝胶的水分状态和微观结构变化。结果表明,添加木薯淀粉不仅改善了猪肉盐溶... 详细信息

研究了添加木薯淀粉对猪肉盐溶蛋白凝胶功能特性的影响。用质构仪、流变仪和离心法测定了凝胶质构、动态流变和保水性的变化,用低场核磁共振仪和扫描电镜分析了凝胶的水分状态和微观结构变化。结果表明,添加木薯淀粉不仅改善了猪肉盐溶蛋白凝胶的质构和保水性能,还改变了凝胶成型温度,单独盐溶蛋白凝胶储能模量在72℃时已达到最大值,添加木薯淀粉凝胶储能模量在80℃达到最大值;当木薯淀粉添加量为1.5%时,凝胶的硬度、弹性和保水性均达到最大,分别为379.02 g、0.85和85.16%,低场核磁共振分析表明添加1.5%木薯淀粉提高了凝胶的结合水和不易流动比例,从而提高了凝胶的保水性能,扫描电镜观察发现此时木薯淀粉主要通过填充效应贯穿在盐溶蛋白分子空隙之间,使凝胶更加紧密和有序。

关键词：盐溶蛋白木薯淀粉流变性质低场核磁共振

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Resting-state brain network remodeling after different nerve reconstruction surgeries:a functional magnetic resonance imaging study in brachial plexus injury rats

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Neural Regeneration Research 2025年第5期20卷 1495-1504页

作者： Yunting Xiang Xiangxin Xing Xuyun hua Yuwen Zhang Xin Xue Jiajia wu Mouxiong Zheng He Wang Jianguang Xu School of Rehabilitation Science Shanghai University of Traditional Chinese MedicineShanghaiChina Engineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation Ministry of EducationShanghaiChina Department of Rehabilitation Medicine Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Department of Traumatology and Orthopedics Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Institute of Science and Technology for Brain-Inspired Intelligence Fudan UniversityShanghaiChina Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence(Fudan University) Ministry of EducationShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected ***,differences among reconstruction strategies at the brain network level have not been *** study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve ***–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper ***-state brain functional magnetic resonance imaging was obtained 7 months after *** independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the *** in intra-network resting-state functional connectivity were compared among the *** muscle reinnervation was assessed by behavioral observation(elbow flexion)and *** results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural *** repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor *** thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve *** areas related to cognition and emotion were enhanced after end-to-side nerve *** study revealed important brain networks related to different nerve *** networks may be potential targets for enhancing motor recovery.

关键词： brain functional networks end-to-end nerve transfer end-to-side nerve transfer independent component analysis nerve repair peripheral plexus injury resting-state functional connectivity

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