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复方生肌玉红膏换药促进肛瘘术后创面愈合的疗效观察

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中国肛肠病杂志 2024年第3期44卷 32-34页

作者：魏洪亮山东省菏泽市中医医院山东菏泽274035

目的:观察复方生肌玉红膏油纱条换药促进肛瘘术后创面愈合的疗效。方法:选取2021年11月至2022年11月,本院80例肛瘘术后患者,随机分成治疗组和对照组,每组各40例。治疗组术后创面外敷生肌玉红膏油纱条,对照组创面外敷凡士林油纱条。观察... 详细信息

目的:观察复方生肌玉红膏油纱条换药促进肛瘘术后创面愈合的疗效。方法:选取2021年11月至2022年11月,本院80例肛瘘术后患者,随机分成治疗组和对照组,每组各40例。治疗组术后创面外敷生肌玉红膏油纱条,对照组创面外敷凡士林油纱条。观察2组临床疗效,创面愈合时间,肉芽组织及上皮组织出现时间,创面疼痛评分及肉芽组织生长评分。结果:治疗组总有效率高于对照组(P<0.05),术后肉芽组织出现时间早于对照组(P<0.05),创面愈合速度明显快于对照组(P<0.05),创面疼痛、水肿及肉芽组织生长评分明显低于对照组(P<0.05)。结论:肛瘘术后采用复方生肌玉红膏纱条换药,临床效果优于传统凡士林纱条换药。可加速创面愈合,减轻术后水肿及疼痛。

关键词：肛瘘术后生肌玉红膏纱条疗效

钢纤维对自密实混凝土工作性能和抗压韧性影响的试验研究

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兰州理工大学学报 2024年第5期50卷 112-117页

作者：韩建平韩维丽文旭皓牛昌林魏宏亮兰州理工大学甘肃省土木工程防灾减灾重点实验室甘肃兰州730050 甘肃建投科技研发有限公司甘肃兰州730050

纤维掺量是影响钢纤维增强自密实混凝土(SFRSCC)性能的重要因素之一.为研究钢纤维掺量对SFRSCC性能的影响,设计制作6组不同纤维掺量的试块,进行工作性能和轴心受压力学性能试验.结果表明,钢纤维能够有效延缓裂缝发展,提高混凝土峰值应变... 详细信息

纤维掺量是影响钢纤维增强自密实混凝土(SFRSCC)性能的重要因素之一.为研究钢纤维掺量对SFRSCC性能的影响,设计制作6组不同纤维掺量的试块,进行工作性能和轴心受压力学性能试验.结果表明,钢纤维能够有效延缓裂缝发展,提高混凝土峰值应变,等效抗压韧性指数随纤维掺量的增加而增大.钢纤维的掺加使得新拌合混凝土流动性降低,与流变特性相关的SFRSCC形状因子λ值低于普通自密实混凝土(SCC).钢纤维的掺加对SFRSCC抗压强度的影响不大,且随着纤维掺量增加,抗压强度呈现先减小后增大的特征.

关键词：钢纤维增强自密实混凝土坍落扩展度轴心受压抗压强度抗压韧性

Synthesis and Antibacterial Activity of Novel Oxazolidinone Analogs Containing Substituted Thiazole/Fused-Bicyclic Groups

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Chemical Research in Chinese Universities 2006年第4期22卷 459-464页

作者： ZHAI Xin ZHAO Yan-fang WANG Jia hong wei HUANG liang GONG Ping School of Pharmaceutical Engineering Shenyang Pharmaceutical University Shenyang 110016 P. R. China

Sixteen novel oxazolidinone analogs containing substituted thiazole/fused-bicyclic（imidazo[ 1,2-b] pyridazine/ imidazo[2,1-b] thiazole） groups were designed and synthesized. A new method for the preparation of the key intermediate compound 11 was proposed. The structures of the target compounds were confirmed by ^1H NMR, IR and MS, and their in vitro antibacterial activities against staphylococcus aureus were evaluated. Among them, compound 16a displays a promising antibacterial activity comparable to that of linezolid.

关键词： Oxazolidinone analog Synthesis Antibacterial activity

Processing of a low-costγ-γ'NiPtAl coating with improved oxidation resistance

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Rare Metals 2024年第6期43卷 2832-2841页

作者： Yan Jiang liang-liang wei Jian He hong-Bo Guo School of Materials Science and Engineering Beihang UniversityBeijing 100191China Key Laboratory of High-Temperature Structural Materials and Protective Coatings Ministry of Industry and Information TechnologyBeihang UniversityBeijing 100191China

A novelγ-γ'(Ni solid solution—Ni_(3)Al)NiPtAl coating was produced on advanced single-crystal(SC)superalloy N5 by electroplating of a thin Pt coating with~3μm in thickness followed by heat treatment at 1000℃in *** comparison,a traditionalγ-γ'NiPtAl coating was also produced by electroplating of a thick Pt coating with~6μm in thickness followed by heat treatment at 1100℃in *** novel coating has a mass gain of~0.5 mg·cm^(-2)after 100 h 1-h cyclic oxidation at 1150℃,showing better oxidation resistance than the traditional *** oxide scale mostly consisting ofα-Al_(2)O_(3)grew on the novel coating because the element Cr from the SC alloy substrate contributes to the formation ofα-Al_(2)O_(3).Pt content in the novel coating has significant effect on the oxidation *** optimized Pt content in the coating is about 16 at%,which is helpful to reduce the diffusion of harmful elements from the substrate into the coating but also to reduce the cost of the coating.

关键词： γ-γ'NiPtAl coating Platinum Oxidation Al_(2)O_(3) Superalloy

Overexpression of decoy receptor 3 in hepatocellular carcinoma and its association with resistance to Fas ligand-mediated apoptosis

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World Journal of Gastroenterology 2005年第38期11卷 5926-5930页

作者： hong-wei Shen Shun-liang Gao Yu-Lian Wu Shu-You Peng Department of Surgery 2^nd Affiliated Hospital of Medical CollegeZhejiang University Hangzhou 310009 Zhejiang Province China

AIM： To characterize the expression and genomic amplification of decoy receptor 3 （DcR3） in hepatocellular carcinoma （HCC） and to evaluate the role of DcR3 in apoptosis.METHODS： We examined 48 cases of HCC for DcR3 expression by RT-PCR and DcR3 gene amplification by quantitative genomic PCR. DcR3 protein was detected by immunohistochemistry. Terminal deoxynucleotidyl transferase-mediated dUTP digoxigenin nick and labeling （TUNEL） was used to identify the apoptosis cells in tissues. Primary hepatoma cell culture and MTT test were used to evaluate the protection against FasL- and chemicalinduced apoptosis by DcR3 expression. RESULTS： DcR3 mRNA overexpression was detected in 60% HCC （29/48） patients. The occurrence of HCC was not associated with amplification of the gene. One sample base substitution was found in three sites as a sequence in Genbank. The expression of DcR3 in HCC was associated with the apoptotic index （0.067±0.04 vs 0.209±0.12, P〈0. 01）, size of mass, stage, and infiltration or metastasis （41.2% vs71.0%, 40% vs75%, 51.8% vs84.6%, P〈0. 05）. DcR3 expression could protect hepatoma cells against apoptosis induced by FasL, but not by chemicals. CONCLUSION： These data suggest that in addition to gene amplification there may be another mechanism underlying DcR3 overexpression. The effect of overexpression of DcR3 on the apoptosis of cancer cells may have direct therapeutic implications for the management of HCC.

关键词： DcR3 Hepatocellular carcinoma Apoptosis

Influence of Bath Composition on Magnetic Properties of Electrodeposited Co-Pt-W Thin Films

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Journal of Iron and Steel Research International 2007年第4期14卷 65-68页

作者： GE hong-liang wei Guo-ying WU Qiong ZHOU Qiao-ying WANG Xin-yan College of Material Science and Engineering China Jiliang University Hangzhou 310018 Zhejiang China

Effect of bath composition （[Co^2＋]/[-Pt^Ⅳ ] and [-WO4^2- ], [cit^-]） and pH on the magnetic properties of electrodeposited Co-Pt-W thin films has been investigated. Electrodeposited Co-Pt-W thin films exhibited strong perpendicular magnetic anisotropy when the ratio of [-Co^2＋ ] to [-Pt^Ⅳ ] was 10 ; cathode current efficiency and perpendicular magnetic anisotropy showed little variations when [WO4^2- ] was lower than 0. 1 mol/L, but perpendicular magnetic anisotropy had strengthened when [WO4^2-] was over 0. 1 mol/L, which could be explained by the fact that the hydrogen evolution could produce pores as magnetic domain pinnings; citrate as complexing reagent can promote the polarization of [Co^2＋] and [Pt^Ⅳ]. As a result, the equilibrium electrode potentials of cobalt and platinum moved to negative direction, which led to the co-deposition of Co, Pt, and W. It was also found out that the as-deposited Co- Pt-W hard magnetic thin films were very homogeneous, smooth, and had the maximum coercivity for the bath pH 8. 5 and the concentration of citrate 0. 26 mol/L.

关键词： electrodeposition Co-Pt-W thin film magnetic property bath composition

Lower Semicontinuity of the Solution Sets to Parametric Generalized Vector Equilibrium Problems

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Journal of Mathematical Research and Exposition 2011年第3期31卷 411-419页

作者： Jing Zhe LI hong wei liang Dan ZHAO College of Mathematics and Statistics Chongqing University Chongqing 401331 P. R. China

In this paper,by a scalarization method,the lower semicontinuity of the solution mappings to two kinds of parametric generalized vector equilibrium problems involving set-valued mappings is established under new assumptions which are weaker than the C-strict *** results extend the corresponding *** examples are given to illustrate our results.

关键词： parametric generalized vector equilibrium problems lower semicontinuity scalarization.

Room temperature non-balanced electric bridge ethanol gas sensor based on a single ZnO microwire

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Chinese Physics B 2020年第1期29卷 463-468页

作者： Yun-Zheng Li Qiu-Ju Feng Bo Shi Chong Gao De-Yu Wang hong-wei liang School of Physics and Electronic Technology Liaoning Normal UniversityDalian 116029China School of Microelectronics Dalian University of TechnologyDalian 116024China

In this paper,ultra-long and large-scaled ZnO microwire arrays are grown by the chemical vapor deposition method,and a single ZnO microwire-based non-balanced electric bridge ethanol gas sensor is *** experimental results show that the gas sensor has good repeatability,high response rate,short response,and recovery time at room temperature(25℃).The response rate of the gas sensor exposed to 90-ppm ethanol is about 93%,with a response time and recovery time are 0.3 s and 0.7 s *** a contrast,the traditional resistive gas sensor of a single ZnO microwire shows very small gas response ***,ethanol gas sensor based on non-balanced electric bridge can obviously enhance gas sensing characteristics,which provides a feasible method of developing the high performance ZnO-based gas sensor.

关键词： ZnO microwire gas sensor room temperature ethanol

Microstructural evolution,mechanical properties and degradation mechanism of PS-PVD quasi-columnar thermal barrier coatings exposed to glassy CMAS deposits

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Rare Metals 2024年第7期43卷 3329-3340页

作者： Zi-Yue Yu liang-liang wei Xing-Ye Guo Bao-Peng Zhang Qing He hong-Bo Guo School of Materials Science and Engineering Beihang UniversityBeijing100191China Key Laboratory of High-Temperature Structure Materials and Protective Coatings(Ministry of Industry and Information Technology) Beihang UniversityBeijing 100191China Surface Engineering Research Institute Chinese Academy of Agricultural Mechanization SciencesBeijing 100083China

Thermal barrier coatings(TBCs) applied in aeroengines tend to be attacked by molten calcia-magnesiaalumino-silicate(CMAS) at high operating ***-stabilized zirconia(YSZ) coatings with quasicolumnar microstructure were fabricated by plasma spray physical vapor deposition(PS-PVD) *** chemic al changes,micros tructural transform ation,mechanical properties and degradation mechanisms of the CM AS-interacted TBCs in the thermal cycling tests were *** YSZ grains were dissolved in the CMAS melts,and then the ZrO_(2) grains were reprecipitated with spherical shape,accompanying with phase transformation from tetragonal(t) to monoclinic(m).The thermal cycling tests reveal that the YSZ coating fails at the early stage due to the attack of *** fractures in intracolumns lead to partial spallation of the *** failure of the coating occurs at the interfaces between thermally grown oxides(TGO) layer and YSZ topcoat;especially,the hardness and Young's modulus of the YSZ coatings increase intensively,as the coatings were infiltrated by the CMAS for a long time.

关键词： CMAS Thermal barrier coatings Young's modulus Thermal cycling behavior PS-PVD