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Is traumatic meniscal lesion associated with acute fracture morphology changes of tibia plateau? A series of arthroscopic analysis of 67 patients

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World Journal of Clinical Cases 2021年第1期9卷 81-90页

作者： Yan-Dong Chen Shu-Xiang Chen hong-guang liu Xiang-Sheng Zhao Wen-Huan Ou Huan-Xi Li hong-Xing Huang 3^rd Institute of Clinical Medicine Guangzhou University of Chinese MedicineGuangzhou 510000Guangdong ProvinceChina Department of Joint Trauma Jiangmen Wuyi Hospital of Traditional Chinese MedicineAffiliated Jiangmen Traditional Chinese Medicine Hospital of Jinan UniversityJiangmen 529031Guangdong ProvinceChina Department of Radiology Jiangmen Wuyi Hospital of Traditional Chinese MedicineJiangmen 529031Guangdong ProvinceChina Science and Education Section The Third Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510378Guangdong ProvinceChina

BACKGROUND Computed tomography(CT)has become a routine preoperative examination for tibial plateau fractures(TPFs).Assessing the location of the fragment and intercondylar eminence fracture can provide clinicians with valuable information;however,the evaluation of traumatic meniscal lesion(TML)and arthroscopic management are *** To predict TML by three-dimensional skeletal anatomy changes in unilateral TPF and bilateral TPF on preoperative thin layer *** Acute fracture of tibial plateau patients undergoing arthroscopic surgery between December 2017 and December 2019 were included in this retrospective *** type,zone,and location of TMLs were diagnosed based on the operation records and/or arthroscopic *** of three-dimensional fracture morphology included the following:Frontal fragment width of plateau,sagittal fragment subsiding distance(FSD),sagittal fracture line distance,sagittal posterior tibial slope,and transversal area ratio of fragment area)on preoperative CT three-dimensional *** correlation of TML with skeletal values was calculated according to unicondylar TPFs and bicondylar *** A total of 67 patients were enrolled in this study,among which 30 patients had TMLs,lateral/medial(23/7).FSD was a particularly positive factor to predict TML,with odds ratio of 2.31(1.26-5.63).On sagittal view of CT,FSD degree of 8 mm and posterior tibial slope exceeding 11.74°implied enhanced risk of TML in bicondylar *** coronal view,once fragment width of plateau surpassed 3 cm,incidence of TML reached 100%.On transverse view,area ratio of fragment as enhanced risk of 5.5%and FSD>4.3 mm for predicting TML were observed in unicondylar *** TML can be predicted by different parameters on preoperative CT views according to unicondylar fractures and bicondylar TPFs.

关键词： Traumatic meniscal lesion Knee Three-dimensional computerized tomography Posterior tibial slope Unicondylar fracture Bicondylar fracture

Impact of task-oriented training based on acupuncture rehabilitation on upper extremity function and quality of life of patients with early stroke

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World Journal of Clinical Cases 2024年第19期12卷 3776-3784页

作者： hong-guang liu Jing-Jing liu Yan-Ping Wang hong-Ying Wang Ao Sun Yue Zhou Ming-Ming Cai Ming-Ming Qi Department of Rehabilitation Medicine Ji Xi Ji Mine HospitalJixi 158100Heilongjiang ProvinceChina Department of Neurology Ji Xi Ji Mine HospitalJixi 158100Heilongjiang ProvinceChina Department of Infectious Diseases Jixi Hengshan District People's HospitalJixi 158100Heilongjiang ProvinceChina Department of Medical Care Ji Xi Ji Mine HospitalJixi 158100Heilongjiang ProvinceChina Department of Science and Education Ji Xi Ji Mine HospitalJixi 158100Heilongjiang ProvinceChina

BACKGROUND Eighty percent of stroke patients develop upper limb dysfunction,especially hand dysfunction,which has a very slow recovery,resulting in economic burden to families and *** To investigate the impact of task-oriented training based on acupuncture therapy on upper extremity function in patients with early *** Patients with early stroke hemiplegia who visited our hospital between January 2021 and October 2022 were divided into a control group and an observation group,each with 50 *** control group underwent head acupuncture plus routine upper limb rehabilitation training(acupuncture therapy).In addition to acupuncture and rehabilitation,the observation group underwent upper limb task-oriented training(30 min).Each group underwent treatment 5 d/wk for 4 *** extremity function was assessed in both groups using the Fugl-Meyer Assessment-Upper Extremity(FMA-UE),Wolf Motor Function Rating Scale(WMFT),modified Barthel Index(MBI),and Canadian Occupational Performance Measure(COPM).Quality of life was evaluated using the Short-Form 36-Item Health Survey(SF-36).Clinical efficacy of the interventions was also *** Before intervention,no significant differences were observed in the FMA-UE,MBI,and WMFT scores between the two groups(P>0.05).After intervention,the FMA-UE,WMFT,MBI,COPM-Functional Mobility and Satisfaction,and SF-36 scores increased in both groups(P<0.05),with even higher scores in the observation group(P<0.05).The observation group also obtained a higher total effective rate than the control group(P<0.05).CONCLUSION Task-oriented training based on acupuncture rehabilitation significantly enhanced upper extremity mobility,quality of life,and clinical efficacy in patients with early stroke.

关键词： Stroke Acupuncture rehabilitation Task-oriented training Upper extremity training

Unraveling brain aging through the lens of oral microbiota

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Neural Regeneration Research 2025年第7期20卷 1930-1943页

作者： Qinchao Hu Si Wang Weiqi Zhang Jing Qu guang-Hui liu State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Hospital of Stomatology Guanghua School of StomatologyGuangdong Provincial Key Laboratory of StomatologySun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Advanced Innovation Center for Human Brain Protection and National Clinical Research Center for Geriatric Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Aging Translational Medicine Center International Center for Aging and CancerBeijing Municipal Geriatric Medical Research CenterXuanwu HospitalCapital Medical UniversityBeijingChina CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijingChina University of Chinese Academy of Sciences BeijingChina Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijingChina Aging Biomarker Consortium BeijingChina State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Beijing Institute for Stem Cell and Regenerative Medicine BeijingChina

The oral cavity is a complex physiological community encompassing a wide range of *** of oral microbiota can lead to various oral infectious diseases,such as periodontitis and tooth decay,and even affect systemic health,including brain aging and neurodegenerative *** studies have highlighted how oral microbes might be involved in brain aging and neurodegeneration,indicating potential avenues for intervention *** this review,we summarize clinical evidence demonstrating a link between oral microbes/oral infectious diseases and brain aging/neurodegenerative diseases,and dissect potential mechanisms by which oral microbes contribute to brain aging and *** also highlight advances in therapeutic development grounded in the realm of oral microbes,with the goal of advancing brain health and promoting healthy aging.

关键词： Alzheimer's disease brain aging multiple sclerosis neurodegeneration neurodegenerative diseases oral microbiota Parkinson's disease periodontitis bacteria Porphyromonas gingivalis

Multiphysics simulation and optimization of the in-situ beneficiation process of ilmenite minerals from lunar regolith

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Science China Earth Sciences 2025年第1期68卷 195-207页

作者： Peng ZHANG Xin liu guanghui liu Wei DAI Hanzhe YANG Haibo ZHENG Zhi WANG Ran NIU Yifan BAI Yang ZHANG Chengbao liu Ge YANG Junwei YANG guang ZHANG Technology and Engineering Center for Space Utilization Chinese Academy of Sciences Beijing Hegong Simulation Co. Ltd

The exploration and utilization of lunar resources have become the major objectives of future lunar exploration missions. The classified collection and processing of lunar minerals is the basic prerequisite for the in-situ exploration and utilization of lunar resources. In this study, we propose a scheme for in-situ separation of magnetic minerals from lunar soils using the dry magnetic separation method. The scheme can realize the purpose of separating magnetic minerals from lunar regolith by altering the motion trajectory of lunar regolith particles with different magnetic properties. Detailed modeling of the dry magnetic separation device is conducted, and the three-dimensional distribution of magnetic parameters is calculated and analyzed. Based on the characterization and analysis of the Chang E-5's samples, the morphologies and physical parameters of lunar regolith particles are modeled and simulated. A discrete element simulation of the motion process of lunar regolith particles under multi-physical field conditions is performed, and the influences of key parameters on the beneficiation performance of lunar magnetic minerals are investigated. Our results indicate that optimal separation and beneficiation of lunar regolith particles can be achieved under specific conditions of magnetic field strength and drum speed. Additionally, we analyze the effects of lunar weak gravity conditions and the charged nature of lunar particles on the beneficiation process, showing that these factors can obviously enhance the beneficiation process of lunar ilmenites. This study demonstrates the feasibility of using the dry magnetic separation method for the beneficiation of magnetic minerals from lunar regolith, providing a theoretical basis for the scientific tasks of collecting, processing, and utilizing lunar mineral resources.

关键词： Lunar regolith In-situ resource utilization Magnetic separation Classified sampling

Contribution of fungal biomass to persistent soil carbon across natural ecosystems

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Science China Earth Sciences 2025年

作者： Xiang WANG guang-Hui YU Yakov KUZYAKOV Bo-Hao YIN Andreas KAPPLER Cong-Qiang liu Bohai Coastal Critical Zone National Observation and Research Station Institute of Surface-Earth System Science School of Earth System Science Tianjin Key Laboratory of Earth Critical Zone Science and Sustainable Development in Bohai Rim Tianjin University Department of Soil Science of Temperate Ecosystems Department of Agricultural Soil Science University of G?ttingen Agro-Technological Institute Peoples Friendship University of Russia (RUDN University) Geomicrobiology Center for Applied Geosciences University of Tübingen Cluster of Excellence EXC 2124 Controlling Microbes to Fight Infection University of Tübingen

Fungi are known to be crucial in the formation and stabilization of soil organic matter through their exudates and dead residues (necromass). Yet, it remains unclear how fungi contribute to the persistence of carbon in soils over millennial scales across biomes. Here, this study fills the knowledge gap by linking fungal carbon stocks with minerals-associated carbon stocks across major biomes. A strong correlation between fungal biomass and reactive mineral-associated carbon stocks in soils across six biomes supports the substantial role of fungi in soil carbon persistence at the global level. High spatial resolution nanoscale secondary ion mass spectrometry revealed that fungi may stabilize carbon by forming organo-mineral associations through their close physical connection to reactive minerals and weathered nanoparticles. We propose a conceptual model that emphasizes the dualistic role of hypha-mineral interactions:(i) fungi accelerate organic matter decomposition by producing reactive oxygen species on the hypha-mineral interfaces, and (ii) fungi stabilize their residues on mineral surfaces, leading to millennial scale persistence of soil C. Concluding, fungi play a fundamental role in ecosystems that extends beyond the decomposition of persistent carbon. They are crucial in stabilizing carbon on mineral surfaces, thereby facilitating the long-term removal of carbon from rapid biotic cycling.

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雌激素对兔脊髓缺血再灌注损伤保护作用的机制研究

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中国现代医学杂志 2017年第16期27卷 30-34页

作者：刘红光张超曾愈程刘芳康颖南华大学附属第一医院乳腺甲状腺外科湖南衡阳421001 南华大学医学院外科学教研室湖南衡阳421001

目的研究雌激素对脊髓缺血再灌注损伤保护作用的机制。方法按随机数表字法把成年的新西兰大白兔分为A^E 5组,每组9只。钳夹肾下腹主动脉20 min恢复再灌注;B组,接受与A组同样的麻醉和手术准备,但不行缺血/再灌注损伤;C组,再灌注开始时从... 详细信息

目的研究雌激素对脊髓缺血再灌注损伤保护作用的机制。方法按随机数表字法把成年的新西兰大白兔分为A^E 5组,每组9只。钳夹肾下腹主动脉20 min恢复再灌注;B组,接受与A组同样的麻醉和手术准备,但不行缺血/再灌注损伤;C组,再灌注开始时从兔耳的缘静脉注射200μg/kg雌激素;D组,再灌注开始时从兔耳的缘静脉注射400μg/kg雌激素;E组,再灌注开始时从兔耳的缘静脉注射800μg/kg雌激素。再灌注48 h后根据Tarlov法对下肢的神经功能进行评分,然后取脊髓组织苏木素-伊红染色法(HE)进行病理分析。结果 Tarlov评分中雌激素组的神经功能评分高于A组,与A组比较有统计学意义(P<0.05)。组织病理表明脊髓的前角运动神经元出现凋亡,有显著坏死。A组脊髓的前角运动神经元计数少于雌激素组,两者比较差异有统计学意义(P<0.05)。结论雌激素可明显改善兔脊髓缺血再灌注的下肢神经功能,使脊髓的前角正常运动神经元的数量增加,减小缺血再灌注的损伤。

关键词：雌激素脊髓缺血再灌注损伤

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“以人为本”与行政程序法治

琼州学院学报 2008年第4期15卷 90-91,76页

作者：包红光刘华湖南科技学院教务处湖南永州425100

本文对"以人为本"与行政程序法治的相关问题加以论述。

关键词：以人为本依法行政行政程序程序法治

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重力式码头胸墙裂缝质量通病的防治

水运工程 2007年第S1期 33-37,40页

作者：昌红霞柳光中交一航局第一工程有限公司天津300456

结合部分重力式码头施工经验,从机理上对码头胸墙裂缝的形状、成因和工程危害进行分析,提出针对性的防治措施,并在鲅鱼圈港区四期工程54#～56#集装箱泊位胸墙的施工中得到应用,收到了较好效果。

关键词：重力式码头胸墙混凝土裂缝防治措施

2014—2016年辽宁省肿瘤医院抗生素类抗肿瘤药的使用情况分析

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现代药物与临床 2017年第7期32卷 1358-1362页

作者：崔红霞刘广宣辽宁省肿瘤医院中国医科大学肿瘤医院药学部辽宁沈阳110042

目的分析2014—2016年辽宁省肿瘤医院抗生素类抗肿瘤药物的使用情况,为临床合理应用抗肿瘤药物提供参考。方法对2014—2016年辽宁省肿瘤医院抗生素类抗肿瘤药物的使用金额、用药频度(DDDs)、日均费用(DDC)及药品排序比(B/A)进行统计与... 详细信息

目的分析2014—2016年辽宁省肿瘤医院抗生素类抗肿瘤药物的使用情况,为临床合理应用抗肿瘤药物提供参考。方法对2014—2016年辽宁省肿瘤医院抗生素类抗肿瘤药物的使用金额、用药频度(DDDs)、日均费用(DDC)及药品排序比(B/A)进行统计与分析。结果 2014—2016年抗生素类抗肿瘤药物的总使用金额和DDDs未出现逐年增长的趋势。吡柔比星的使用金额逐年递增。表柔比星、多柔比星脂质体、多柔比星使用金额逐年递减。从排序来看,表柔比星、吡柔比星与多柔比星脂质体的使用金额连续3年排前3位。表柔比星与吡柔比星的DDDs排名持续居于前2位。抗生素类抗肿瘤药物的DDC及其排序相对稳定,多柔比星脂质体的DDC持续居于首位。大部分抗生素类抗肿瘤药物的B/A值接近于1.00。结论辽宁省肿瘤医院抗生素类抗肿瘤药物使用基本合理,符合安全、有效、经济、方便的原则。

关键词：抗生素抗肿瘤药销售金额用药频度日均费用排序比