检索结果-南通市图书馆

Regulation of gene-edited plants in Europe:from the valley of tears into the shining sun?

aBIOTECH 2024年第2期5卷 231-238页

作者： holger Puchta Department of Molecular Biology Joseph Gottlieb Kolreuter Institute for Plant SciencesKarlsruhe Institute of Technology(KIT)Fritz-Haber-Weg 476131 KarlsruheGermany

Some 20 years ago,the EU introduced complex regulatory rules for the growth of transgenic crops,which resulted in a de facto ban to grow these plants in fields within most European *** the rise of novel genome editing technologies,it has become possible to improve crops genetically in a directed way without the need for incorporation of foreign ***,in 2018,the European Court of justice ruled that such gene-edited plants are to be regulated like transgenic *** then,European scientists and breeders have challenged this decision and requested a revision of this outdated ***,after 5 years,the European Commission has now published a proposal on how,in the future,to regulate crops produced by new breeding *** proposal tries to find a balance between the different interest groups in *** one side,genetically modified plants,which cannot be discerned from their natural counterparts,will exclusively be used for food and feed and are-besides a registration step-not to be regulated at *** the other side,plants expressing herbicide resistance are to be excluded from this regulation,a concession to the strong environmental associations and NGOs in ***,edited crops are to be excluded from organic farming to protect the business interests of the strong organic sector in ***,if this law passes European parliament and council,unchanged,it will present a big step forward toward establishing a more sustainable European agricultural ***,it might soon be possible to develop and grow crops that are more adapted to global warming and whose cultivation will require lower amounts of ***,there is still a long way to go until the law is *** often,the storm of arguments raised by the opponents,based on irrational fears of mutations and a naive understanding of nature,has fallen on fruitful ground in Europe.

关键词： Genetically modified organism Cisgenesis Gene editing CRISPR/Cas Regulation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gut microbiome regulates inflammation and insulin resistance:a novel therapeutic target to improve insulin sensitivity

引用

Signal Transduction and Targeted Therapy 2024年第3期9卷 825-827页

作者： Dilvin Semo holger Reinecke Rinesh Godfrey Vascular Signalling Molecular CardiologyDepartment of Cardiology I-Coronary and Peripheral Vascular DiseaseHeart FailureUniversity Hospital Münster48149 MünsterGermany

In a recent study published in Nature,Takeuchi et *** a multiomics strategy in humans to provide compelling evidence that increased carbohydrate metabolism by the gut microbiota contributes to insulin resistance(IR).The authors uncovered a previously unknown link between elevated gut monosaccharides and host inflammatory cytokines and suggest potential intervention opportunities to combat IR by targeting specific gut microbial species.

关键词： metabolism inflammation al.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

GRADE指南：Ⅲ.证据质量分级

引用

中国循证医学杂志 2011年第4期11卷 451-455页

作者： Howard Balshem Mark Helfanda holger j.schunemann Andrew D.Oxman Regina Kunz jan Brozek Gunn E.Vist Yngve Falck-Ytter joerg Meerpohl Susan Norris Gordon H.Guyatt GRADE工作组李幼平杨晓妍高霑

本文介绍证据质量分级的GRADE方法。GRADE将证据质量分为高、中、低和极低四个级别。该分级应用于证据群,而非针对个别研究。系统评价中,质量反映了我们认为效应估计值正确的把握度。对推荐意见而言,质量反映了我们认为效应估计值足以... 详细信息

本文介绍证据质量分级的GRADE方法。GRADE将证据质量分为高、中、低和极低四个级别。该分级应用于证据群,而非针对个别研究。系统评价中,质量反映了我们认为效应估计值正确的把握度。对推荐意见而言,质量反映了我们认为效应估计值足以支持某特定推荐的把握度。随机对照试验初定为高质量证据,观察性研究初定为低质量证据。GRADE中所使用的质量一词不只是意味着偏倚风险,还可能受研究结果的不精确性、不一致性和间接性,及发表偏倚的影响。此外,若干因素可增加我们对效应估计值的把握度。GRADE提供了一种系统方法来思考并报告各因素。GRADE将评估证据质量的过程与给出推荐建议的过程分开。推荐强度的判断不仅依赖于证据质量。

关键词：质量评价证据群不精确性间接性不一致性发表偏倚

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fatty acids derived from oviposition systems guide female black soldier flies(Hermetia illucens)toward egg deposition sites

引用

Insect Science 2024年第4期31卷 1231-1248页

作者： Patrick Klüber Emna Arous jeanny jerschow Marco Fraatz Daniel Bakonyi Martin Rühl holger Zorn Department Bioresources Fraunhofer Institute for Molecular Biology and Applied EcologyGiessenGermany Institute of Food Chemistry and Food Biotechnology Justus Liebig University GiessenGiessenGermany

The black soldier fly,Hermetia illucens,comes with big promises for industrial purposes since its larvae feed polyphagously on a broad spectrum of organic ***,research focusing on adult flies is scarce,which is inconsistent with their reproductive relevance within the rearing *** particular,directed oviposition is a challenge in artificial ***,decomposing organic matter is commonly used as oviposition substrate,which has extensive potential for improvement in view of the lack of standardization and the risk of microbial ***,we identified three fatty acids and one fatty acid methyl ester derived from the surface of old oviposition sites and targeted to elucidate their effect on preference behavior and oviposition site selection using Y-olfactometry and prepared oviposition sites,*** to tetradecanoic acid attracted gravid females and stimulated oviposition most strongly,while decanoic acid demonstrated a repulsive *** kept in mixed-sex populations were attracted by tetradecanoic acid,resulting in a higher egg mass found in the compound box(3.0–11.4 fold),a≥2.3 fold reduction of nonspecifically deposited eggs,and the highest total egg ***,decanoic and dodecanoic acid caused females to lay a greater proportion of eggs nonspecifically outside both *** data suggest that fatty acids,especially tetradecanoic acid,are important cues for oviposition site selection in black soldier *** order to achieve a directed oviposition behavior,the role of further short-and long-chain fatty acids as attractants should be examined.

关键词： black soldier fly Hermetia illucens fatty acids insects as food and feed oviposition oviposition site selection tetradecanoic acid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparison between ozonesonde measurements and satellite retrievals over Beijing,China

引用

Atmospheric and Oceanic Science Letters 2024年第1期17卷 14-20页

作者： jinqiang Zhang Yuejian Xuan jianchun Bian holger Vomel Yunshu Zeng Zhixuan Bai Dan Li Hongbin Chen Key Laboratory of Middle Atmosphere and Global Environment Observation Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijingChina College of Atmospheric Sciences Lanzhou UniversityLanzhouChina National Center for Atmospheric Research BoulderCOUSA Electronic Engineering College Chengdu University of Information TechnologyChengduChina

从2013年开始,作者团队使用自主研发电化学原理臭氧探空仪在华北平原北京地区进行每周一次观测.本研究首次使用2013-2019年期间北京地区臭氧探空数据评估Aqua卫星搭载大气红外探测仪(AIRS)和Aura卫星搭载微波临边探测器(MLS)反演垂直臭... 详细信息

从2013年开始,作者团队使用自主研发电化学原理臭氧探空仪在华北平原北京地区进行每周一次观测.本研究首次使用2013-2019年期间北京地区臭氧探空数据评估Aqua卫星搭载大气红外探测仪(AIRS)和Aura卫星搭载微波临边探测器(MLS)反演垂直臭氧廓线,并对比臭氧探空,AIRS和Aura卫星搭载臭氧监测仪(OMI)臭氧柱总量结果.尽管臭氧探空与卫星反演垂直臭氧廓线在局部高度处差异较大,但整体来说两者较为接近(相对偏差大多<10%).臭氧探空,AIRS和OMI三种仪器测量臭氧柱总量的年变化特征较为一致,其年均臭氧柱总量分别为351.8±18.4 DU,348.8±19.5 DU和336.9±14.2 DU.后续对国内多站点观测数据分析将有助于进一步理解臭氧探空与卫星反演臭氧资料在不同区域的一致性.

关键词：臭氧探空卫星反演垂直臭氧廓线臭氧柱总量华北平原

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Driving factors behind multiple populations

引用

Science China(Physics,Mechanics & Astronomy) 2024年第5期67卷 172-181页

作者： Ruoyun Huang Baitian Tang Chengyuan Li Doug Geisler Mario Mateo Ying-Yi Song holger Baumgardt julio A.Carballo-Bello Yue Wang jundan Nie Bruno Dias joséG.Fernández-Trincado School of Physics and Astronomy Sun Yat-sen UniversityZhuhai 519082China CSST Science Center for the Guangdong-Hong Kong-Macao Greater Bay Area Zhuhai 519082China Departamento de Astronomía Universidad de ConcepcionConcepcionChile Instituto de Investigación Multidisciplinario en Ciencia y Tecnología Universidad de La SerenaLa SerenaChile Departamento de Astronomía Facultad de CienciasUniversidad de La SerenaChile Department of Astronomy University of MichiganAnn Arbor 48109USA David A.Dunlap Department of Astronomy&Astrophysics University of TorontoToronto ON M5S 3H4Canada Dunlap Institute for Astronomy&Astrophysics University of TorontoToronto ON M5S 3H4Canada School of Mathematics and Physics The University of QueenslandSt.Lucia QLD 4072Australia Instituto de Alta Investigación Universidad de TarapacáAricaChile CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Instituto de Astrofísica Departamento de Ciencias FísicasFacultad de Ciencias ExactasUniversidad Andres BelloSantiagoChile Instituto de Astronomía Universidad Católica del NorteAntofagastaChile

Star clusters were historically considered simple stellar populations,with all stars sharing the same age and initial chemical ***,the presence of chemical anomalies in globular clusters(GCs),called multiple stellar populations(MPs),has challenged star formation theories in dense *** studies show that mass,metallicity,and age are likely controlling parameters for the manifestation of *** the limit between clusters with/without MPs in physical parameter space is crucial to reveal the driving mechanism behind their *** this study,we look for MP signals in Whiting 1,which is traditionally considered a young *** the Magellan telescope,we obtained low-resolution spectra withinλλ=3850-5500?for eight giants of Whiting *** measured the C and N abundances from the CN and CH spectral indices.C and N abundances have variations comparable with their measurement errors(~0.1 dex),suggesting that MPs are absent from Whiting *** these findings with literature studies,we propose a limit in the metallicity *** compactness index parameter space,which relatively clearly separates star clusters with/without MPs(GCs/open clusters).This limit is physically *** a larger scale,the galactic environment determines cluster compactness and metallicity,leading to metal-rich,diffuse,old clusters formed ex *** proposed limit also impacts our understanding of the formation of the Sagittarius dwarf galaxy:star clusters formed after the first starburst(age≤8-10 Gyr).These clusters are simple stellar populations because the enriched galactic environment is no longer suitable for MP formation.

关键词： stellar galactic galaxy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

现代化的刀具物流中心

引用

现代制造 2024年第6期 24-26页

作者： holger Häring 不详

新建的物流中心花费了200多亿欧元,这是霍夫曼欧洲公共有限责任公司(Hoffmann SE)100多年历史中的最大一笔投资。与技术中心毗邻的刀具物流中心是霍夫曼集团公司全球最大的、高性能的中央仓库。霍夫曼集团公司的刀具物流中心占地面积高... 详细信息

新建的物流中心花费了200多亿欧元,这是霍夫曼欧洲公共有限责任公司(Hoffmann SE)100多年历史中的最大一笔投资。与技术中心毗邻的刀具物流中心是霍夫曼集团公司全球最大的、高性能的中央仓库。霍夫曼集团公司的刀具物流中心占地面积高达21.5公顷(1公顷=10 000 m^(2)),拥有破纪录的大约10万m^(2)、相当于13个足球场的可用面积。物流中心的核心是一套穿梭车仓库、大约560 000个储物架口。

关键词：物流中心占地面积穿梭车霍夫曼欧元仓库刀具足球场

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Erratum to:Superlubricity of epitaxial monolayer WS_(2)on graphene

引用

Nano Research 2024年第6期17卷 5754-5754页

作者： holger Büch Antonio Rossi Stiven Forti Domenica Convertino Valentina Tozzini Camilla Coletti Center for Nanotechnology Innovation@NEST Istituto Italiano di TecnologiaPiazza S.Silvestro 1256127 PisaItaly NEST Istituto Nanoscienze–CNR and Scuola Normale SuperiorePiazza San Silvestro 1256127 PisaItaly Graphene Labs Istituto Italiano di TecnologiaVia Morego 3016163 GenovaItaly

The article"Superlubricity of epitaxial monolayer WS2 on graphene",written by holger Büch,Antonio Rossi,Stiven Forti,Domenica Convertino,Valentina Tozzini,and Camilla Coletti,was originally published electronically on the publisher’s internet portal(currently SpringerLink)on june 18th 2018 without open *** the author(s)’decision to opt for Open Choice the copyright of the article changed in August 2018 to©The Author(s)2018 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License(http://***/licenses/by/4.0/),which permits use,duplication,adaptation,distribution and reproduction in any medium or format,as long as you give appropriate credit to the original author(s)and the source,provide a link to the Creative Commons license and indicate if changes were made.

关键词： monolayer epitaxial license

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Broadening the applicability of CRISPR/Cas9 in plants

引用

Science China(Life Sciences) 2018年第1期61卷 126-127页

作者： holger Puchta Botanical Institute Karlsruhe Institute of Technology

The use of CRISPR（clustered regulatory interspaced short palindromic repeats）Cas9 is revolutionizing genome engineering—not only in plants（Schiml and Puchta,2016）.This is due to the fact that with high specificit... 详细信息

关键词： Broadening the applicability of CRISPR/Cas9 in plants NAG

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Condition-dependence and sexual ornamentation： Effects of immune challenges on a highly sexually dimorphic grasshopper

引用

Insect Science 2018年第4期25卷 617-630页

作者： j. Pablo Valverde Hendrik Eggert joachim Kurtz holger Schielzeth Department of Evolutionary Biology Bielefeld University Bielefeld Germany Institute for Evolution and Biodiversity Westfalische Wilhelms-Universitat Munster Munster Germany and 3 Department of Population Ecology Institute of Ecology Friedrich Schiller University Jena Germany Department of Population Ecology Institute of Ecology Friedrich Schiller University Jena Germany

Sexual ornaments contribute substantially to phenotypic diversity and it is particularly relevant to understand their evolution. Ornaments can assume the function of signals-of-quality that the choosy sex uses to evaluate potential mating partners. Often there are no obvious direct benefits and investment into mate choice is primarily rewarded by beneficial alleles that are inherited to the offspring. Inter-sexual communication via sexual ornaments requires honesty of the sexual signal, yet the question of what maintains honesty remains only partially solved. One solution is that honesty is maintained by trait expression being dependent on individual condition, since condition-dependent trait expression offers an effectively inexhaustible source of genetic variability. Here we test in the highly sexually dimorphic club-legged grasshopper Gomphocerus sibiricus if putative sexual ornaments, in particular the striking front-leg clubs, are more strongly affected by a lipopolysaccharide （LPS） immune challenge than putatively not sexually selected traits. Our results show overall little condition-dependent expression of morphological and song traits, with sexually selected traits exhibiting effects comparable to nonsexually selected traits （with the possible exception of stridulatory file length and syllable-to-pause ratio in advertisement songs）. Interestingly, field observations of individuals of lethally parasitized individuals suggest that a very strong environmental challenge can specifically affect the expression of the front-leg clubs. The presence of 1% of males in natural populations with missing or heavily deformed clubs plus 5% with minor club deformations furthermore indicate that there are risks associated with club development during final ecdysis and this might act as a filter against deleterious alleles.

关键词： Acrididae honest signaling Orthoptera phenotypic plasticity sexualselection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：