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Prevalence of Female Sexual Dysfunction among Women with Pelvic Organ Prolapse Diagnosed by Pisq-12 and Related Factors in Hung Vuong Hospital, Vietnam

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Open Journal of Obstetrics and Gynecology 2019年第7期9卷 1005-1018页

作者： Huynh Nguyen Khanh Trang Pham Hung Cuong hoang thi diem tuyet Pham Ngoc Thach University of Medicine Ho Chi Minh City Vietnam Hung Vuong Hospital Ho Chi Minh City Vietnam University of Medical and Pharmacy Ho Chi Minh City Vietnam

Pelvic organ prolapsed is a common problem today, and it has been gradually increasing because of the longevity of women. Pelvic organ prolapse can result in negative psychological feelings that affect on women’s sexual activity. Methods: There is a cross-sectional study on sexual dysfunction in 296 women with pelvic organ prolapse grade II and III followed up at gynecological-pelvic floor unit of Hung Vuong hospital from 09/2017 to 06/2018. Results: The prevalence of female sexual dysfunction in PISQ-12 was 76.4% and 95% CI [71.6 - 81.2]. The rate of female sexual dysfunction in turn is: 1) Behavioral-Emotional: 93.6% 95% CI [90.8 - 96.4]. 2) Physiology: 62.2% CI 95% [56.7 - 67.7]. 3) Relationship to partner: 89.5% 95% CI [86.0 - 93.0]. Factor related to sexual dysfunction in women with pelvic organs (p < 0.05) is general sexual dysfunction: 1) Age group: women over age 55 increased generally the risk of sexual dysfunction, OR = 5.89, 95% CI [1.38 - 25.20]. 2) Diabetes mellitus increased the risk of sexual dysfunction with OR = 5.03, 95% CI [1.42 - 17.82]. 3) Patients with previous abortions reduced the risk of sexual dysfunction with OR = 0.49 95% CI [0.27 - 0.90]. Conclusion: Research on quality of life in pelvic organ prolapse should be considered more in the future.

关键词： Pelvic Organ Prolapse Sexual Dysfunction Pelvic Organ Prolapse Quantification System (POP-Q) Pelvic Organ Prolapse/Urinary Incontinence Sexual Function Questionnaire-12 (PISQ-12)

The Outcome of 40 Patients Becoming Pregnancy after Conservative Treatment of Cesarean Scar Pregnancy

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Case Reports in Clinical Medicine 2020年第12期9卷 376-384页

作者： Nguyen Hong Hoa Nguyen thi Thanh Thao hoang thi diem tuyet Van Phung Thong Department of Obstetrics & Gynecology Faculty of Medicine University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam Department of Obstetrics Hung Vuong Hospital Ho Chi Minh City Vietnam Department of Obstetrics Tu Du Hospital Ho Chi Minh City Vietnam

Background: The rate of uterus is successfully conserved following the treatment of scar pregnancy which is high so pregnancy outcome following caesarean scar ectopics is getting more and more attention. Objectives: To assess pregnancy course and outcome after conservative treatment of cesarean scar pregnancy. Methods: A retrospective case series of 40 patients become pregnancy after conservative treatment of cesarean scar pregnancy by Foley or Methotrexate and aspiration. Patients in present study were treated at Hung Vuong and Tu Du Hospital between 2015 and 2017. A telephone follow-up was conducted after cesarean scar pregnancy (CSP) treatment. The outcomes of these subsequent pregnancies and mode of delivery were all recorded. Results: In 40 pregnancies, there are 22 cases of intrauterine pregnancy with childbirth (55%);all babies were born healthy, with no complications recorded in pregnancy. 12 Women had recurrent scar ectopic (30%). There were 2 abortion cases, 2 cases of ectopic pregnancy, and 2 cases of early miscarriage. Conclusions: Our study shows that reproductive outcomes following treatment of caesarean scar ectopic pregnancies are favourable. The risk of recurrent caesarean scar ectopic pregnancy is a concern.

关键词： Caesarean Scar Pregnancy Reproductive Outcomes

Physical Examination Indicated Rescue Cerclage to Improve Live Birth Rate at Hung Vuong Hospital in Vietnam

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Open Journal of Obstetrics and Gynecology 2020年第3期10卷 400-408页

作者： Huynh Nguyen Khanh Trang Tran thi Ngoc Tam Pham Huynh Phuc Hung hoang thi diem tuyet Pham Ngoc Thach University of Medicine HCMC Vietnam Hung Vuong Hospital HCMC Vietnam

Emergency cerclage with advanced cervical dilatation and bulging of fetal membranes is still challenging to obstetricians.?Objective:?To identify the live birth rate after physical examination indicated rescue cerclage. Methods:?A retrospective cohort study of 36 pregnant women, who underwent rescue cerclage at Hung Vuong hospital from January 2015 to January 2019. Selection criteria: cervical dilation 10 to 40 mm, at 20 to 30 gestational weeks. Exclusion criteria: multiple pregnancy, birth defects, pregnancy termination due to maternal or fetal indications. Results: Delivery of live infant rate was 72.22%;mean pregnancy prolongation was 42.8 ±?34.15 days. Early live birth rate was 77.78%. The percentage of delivery after 34 and 37 weeks was 44.45% and 27.78%, respectively. Live birth weight was 400 to 3600?g, with mean being 1878.06 ±?1049.04?g. No procedure-related complication was observed. Conclusions:?Rescue cerclage may be an effective and safe method in prolonging pregnancy and improving neonatal outcome in women with cervical dilation 10 to 40 mm. It should be considered as a viable option for women with a dilated cervix in 20 to 30 gestational weeks. Future controlled studies are needed.

关键词： Emergency Cerclage Delivery of Live Infant Rate

Prevalence, risk factors, and BRAF mutation of colorectal sessile serrated lesions among Vietnamese patients

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World Journal of Clinical Oncology 2024年第2期15卷 290-301页

作者： Nhu thi Hanh Vu Huy Minh Le diem thi-Ngoc Vo hoang Anh Vu Nhan Quang Le Dung Dang Quy Ho Duc Trong Quach Department of Internal Medicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam GI Endoscopy Department University Medical Center at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Histology-Embryology and Pathology University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Center for Molecular Biomedicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Endoscopy Cho Ray HospitalHo Chi Minh 700000Viet Nam

BACKGROUND Sessile serrated lesions(SSLs)are considered precancerous colorectal lesions that should be detected and removed to prevent colorectal *** studies in Vietnam mainly investigated the adenoma pathway,with limited data on the serrated *** To evaluate the prevalence,risk factors,and BRAF mutations of SSLs in the Vietnamese *** this is a cross-sectional study conducted on patients with lower gastrointestinal symptoms who underwent colonoscopy at a tertiary hospital in *** were diagnosed on histopathology according to the 2019 World Health Organi-zation *** mutation analysis was performed using the Sanger DNA sequencing *** multivariate logistic regression model was used to determine SSL-associated *** There were 2489 patients,with a mean age of 52.1±13.1 and a female-to-male ratio of 1:*** prevalence of SSLs was 4.2%[95%confidence interval(CI):3.5-5.1].In the multivariate analysis,factors significantly associated with SSLs were age≥40[odds ratio(OR):3.303;95%CI:1.607-6.790],male sex(OR:2.032;95%CI:1.204-3.429),diabetes mellitus(OR:2.721;95%CI:1.551-4.772),and hypertension(OR:1.650,95%CI:1.045-2.605).The rate of BRAF mutations in SSLs was 35.5%.CONCLUSION The prevalence of SSLs was 4.2%.BRAF mutations were present in one-third of *** risk factors for SSLs included age≥40,male sex,diabetes mellitus,and hypertension.

关键词： Colorectal cancer Sessile serrated lesion BRAF mutation Risk factors Diabetes mellitus Hypertension

How to"pick up"colorectal serrated lesions and polyps in daily histopathology practice:From terminologies to diagnostic pitfalls

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World Journal of Clinical Oncology 2024年第9期15卷 1157-1167页

作者： Thai H Tran Vinh H Nguyen diem TN Vo Department of Pathology Da Nang HospitalDa Nang 50000Viet Nam Department of Pathology University Medical Center Ho Chi Minh CityHo Chi Minh 70000Viet Nam Department of Histology-Embryology and Pathology University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 70000Viet Nam

Over the last decade,our knowledge of colorectal serrated polyps and lesions has significantly improved due to numerous studies on this group of precursor *** lesions were misleading as benign before 2010,but they are currently reclassified as precancerous lesions that contribute to 30%of colorectal cancer through the serrated neoplasia *** World Health Organization updated the classification for serrated lesions and polyps of the colon and rectum in 2019,which is more concise and applicable in daily *** responsible authors prescribe that“colorectal serrated lesions and polyps are characterized by a serrated(sawtooth or stellate)architecture of the epithelium.”From a clinical standpoint,sessile serrated lesion(SSL)and SSL with dysplasia(SSLD)are the two most significant *** these advancements,the precise diagnosis of SSL and SSLD based mainly on histopathology remains challenging due to various *** review describes the nomenclature and the terminology of colorectal serrated polyps and lesions and highlights the diagnostic criteria and obstacles encountered in the histopathological diagnosis of SSL and SSLD.

关键词： Sessile serrated lesions Sessile serrated lesions with dysplasia Serrated polyps Sessile serrated adenoma Benign hyperplastic polyps Serrated lesions/polyps

Co-Infection of Parvovirus B19, CMV and BK Virus after Renal Transplantation

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International Journal of Clinical Medicine 2018年第11期9卷 820-825页

作者： hoang thi diem Thuy Department of Nephrology and Endocrinology Children Hospital 2 Ho Chi Minh City Vietnam

Background: Parvovirus B19 is the agent causing a regenerative anemia in organ transplant recipients, due to their immunodepressive status. The diagnosis is usually confirmed by the presence of virus in the blood and bone marrow via the PCR technique. There is a potential co-infection with other opportunistic viruses in the transplanted patients. However, this population is not routinely screened for Parvovirus B19 infection. Case Report: A 14-year-old male patient who received living-donor kidney transplantation developed a severely progressive and aregenerative anemia four weeks later. PCR of Parvovirus B19 was positive from bone marrow aspiration. There were concomittant CMV and BK virus co-infection. The treatment included a reduction of immunosuppressants, intravenous gamma globulin. Valganciclovir has been prescribed for three months that could negativate the CMV blood load. At the end, there was an eradication of parvovirus in the bone marrow. Conclusion: this first reported case in Viet Nam which informed that infection with Parvovirus B19 should be investigated in the transplanted population when a regenerative anemia is present. Otherwise, a screening strategy for Parvovirus B19 should also be considered.

关键词： Parvovirus Kidney Transplantation Co-Infection

Fuzzy MCDM for Improving the Performance of Agricultural Supply Chain

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Computers, Materials & Continua 2022年第11期73卷 4003-4015页

作者： Le thi diem My Chia-Nan Wang Nguyen Van Thanh Department of Industrial Engineering and Management National Kaohsiung University of Science and TechnologyKaohsiung CityTaiwan Faculty of Commerce Van Lang UniversityHo Chi Minh CityVietnam

Fertilizer industry in Vietnam and globally have entered the saturation *** the growth rate slowing down,this poses challenges for the development impetus of the fertilizer industry in the next *** fact,over the past few decades,Vietnam’s crop industry has abused excessive investment in chemical fertilizers,with organic fertilizers are rarely used or not at all,limiting crop productivity,increasing pests and *** develop sustainable agriculture,Vietnam’s crop industry must limit the use of chemical fertilizers,increase the use of environmentally friendly organic and natural mineral fertilizers to produce clean agricultural products which is ***,it is necessary to consider and choose the right supplier to ensure the goal of sustainable *** Fuzzy Analytic Hierarchy Process(SF-AHP),and the combinative distance-based assessment(CODAS)are new Multicriteria Decision Making(MCDM)method which can be used to solve supplier selection *** paper uses an effective solution based on a combined the concept of triple bottom line(TBL),SF-AHP and CODAS approach to help agriculture companies that need to select the best fertilizer *** research can support supply chain managers to achieve supply chain systems that reduce not only sourcing costs,but also develop sustainable agriculture.

关键词： Fuzzy theory MCDM model fertilizer agricultural supply chain optimization

Surface PEGylation of hollow mesoporous silica nanoparticles via aminated intermediate

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Progress in Natural Science:Materials International 2019年第6期29卷 612-616页

作者： thi Ngoc Tram Nguyen diem-Huong Nguyen-Tran Long Giang Bach Tran hoang Du Truong Ngoc Thuy Trang Le Dai Hai Nguyen Tra Vinh University Institute of Applied Materials Science Vietnam Academy of Science and Technology Graduate University of Science and Technology Vietnam Academy of Science and Technology Nguyen Tat Thanh University 5. Institute of Research and Development Duy Tan University

A hybrid of organic/inorganic system, hollow mesoporous silica nanoparticles functionalized with poly(ethylene glycol), was synthesized in the presence of coupling agent and aminated ends. Doxorubicin(DOX) was used as a model drug to evaluate the effect of PEGylation on the loading capacity and release pattern of the *** with transmission electron microscopy(TEM) and scanning electron microscopy(SEM), X-ray diffraction(XRD), nitrogen adsorption-desorption, thermogravimetric analysis(TGA) and Fourier transformed infrared(FTIR) confirmed the PEG conjugation, as well as the amorphous mesoporous nature of the synthesized particles. Due to the capping effect of PEG molecules over the pores in the silica structure, the synthesized system was able to retain higher amount of cargo and establish a controlled manner when releasing.

关键词： Hollow mesoporous silica nanoparticles mPEG PEGylation Surface modification

Response surface method for modeling the removal of carbon dioxide from a simulated gas using water absorption enhanced with a liquid-film-forming device

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Journal of Environmental Sciences 2018年第3期30卷 116-126页

作者： diem-Mai Kim Nguyen Tsuyoshi Imai Thanh-Loc thi Dang Ariyo Kanno Takaya Higuchi Koichi Yamamoto Masahiko Sekine Graduate School of Environmental Sciences and Engineering Yamaguchi University Graduate School of Sciences and Technology for Innovation Yamaguchi University Department of Environmental Science College of Sciences Hue University

this paper presents the results from using a physical absorption process to absorb gaseous CO2mixed with N2using water by producing tiny bubbles via a liquid-film-forming device（LFFD）that improves the solubility of CO2in *** influence of various parameters—pressure,initial CO2concentration,gas-to-liquid ratios,and temperature—on the CO2removal efficiency and its absorption rate in water were investigated and estimated thoroughly by statistical polynomial models obtained by the utilization of the response surface method（RSM）with a central composite design（CCD）.Based on the analysis,a high efficiency of CO2capture can be reached in conditions such as low pressure,high CO2concentration at the inlet,low gas/liquid ratio,and low *** instance,the highest removal efficiency in the RSM–CCD experimental matrix of nearly 80%occurred for run number 20,which was conducted at 0.30 MPa,CO2concentration of 35%,gas/liquid ratio of 0.71,and temperature of 15℃.Furthermore,the coefficients of determination,R^2,were 0.996 for the removal rate and 0.982 for the absorption rate,implying that the predicted values computed by the constructed models correlate strongly and fit well with the experimental *** results obtained provide essential information for implementing this method properly and effectively and contribute a promising approach to the problem of CO2capture in air pollution treatment.

关键词： Carbon dioxide Water dissolution Liquid-film Response surface method (RSM)