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Chemical Research in Chinese Universities 2010年第4期26卷 532-536页

作者： ROW Kyung-ho Department of Chemical Engineering Inha University

A linear solvation energy relationships（LSERs） model was used to examine the fundamental chemical interactions governing the retention of 9 organic compounds on a C18 column by means of reversed-phase high performance liquid cbromatography（RP-HPLC）. Three ionic liquids, 1-hexyl-3-methylimidazolium tetrafluoroborate （[Hmin][BF4]）, 1-butyl-3-methylimidazolium tetrafluoroborate（[Bmin][BF4]） and 1-octyl-3-methylimidazolium tetrafluoroborate（[OMIm][BF4]） as additives, were added to a methanol-water mobile phase. The effects of these three ionic liquids additives on the retention of nine organic compounds were investigated, and a comparison between the predicted and experimental retention factors was made via the LSERs model, which indicated that the LSERs model could be used to reproduce the experimental retention factors of the solutes under different mobile phase conditions. It is also a useful tool for modeling the interactions of the solutes between the stationary and mobile phases and evaluating the retention characteristics of HPLC.

关键词： Retention factor Ionic liquid Additive Mobile phase Model

Revisiting oral fluoropyrimidine with cetuximab in metastatic colorectal cancer: Real-world data in Chinese population

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World Journal of Gastrointestinal Oncology 2019年第11期11卷 1031-1042页

作者： Ka-On Lam Man-Chi Fu Kin-Sang Lau Kam-Mo Lam Cheuk-Wai Choi Wan-Hang Chiu Cheng-Man Yuen Lai-Han Kwok Fong-Kit Tam Wing-Lok Chan Sum-Yin Chan Pui-Ying ho To-Wai leung ho-Fun Lee Department of Clinical Oncology LKS Faculty of MedicineThe University of Hong KongHong KongChina Department of Clinical Oncology Queen Mary HospitalHong KongChina Clinical Oncology Centre The University of Hong Kong-Shenzhen HospitalShenzhen 518053Guangdong ProvinceChina Department of Pharmacy Queen Mary HospitalHong KongChina Department of Diagnostic Radiology LKS Faculty of MedicineThe University of Hong KongHong KongChina

BACKGROUND Cetuximab in combination with oral fluoropyrimidine(FP)remains controversial in metastatic colorectal cancer(mCRC).In view of the regional variation in the tolerability of FP,we conducted a retrospective analysis to compare oral FP with infusional FP in combination with cetuximab in Chinese *** To compare the efficacy and safety profile of cetuximab in combination with oral FP and infusional FP in Chinese population in the real-world *** A retrospective cohort study was done to analyse consecutive patients with Kras wild-type mCRC who received first-line treatment with cetuximab and FP-based chemotherapy in our unit from January 2010 to December ***-five eligible patients were *** median follow-up of our cohort was 65.0 *** The median progression-free survival(mPFS)and median overall survival(mOS)of the entire cohort were 9.66 mo(95%CI:7.72–12.5)and 25.8 mo(95%CI:18.7–35.6),*** oral FP and infusional FP,there was no statistical significant difference in the mPFS[9.79 mo(95%CI:7.49–12.7)vs 9.63 mo(95%CI:6.34–13.4);P=0.72]and mOS[25.8 mo(95%CI:15.2–35.6)vs 26.3 mo(95%CI:18.7–41.2);P=0.63].Grade 3 or above adverse events were reported in 28.4%of patients,being similar with oral and infusional FP,and included 10.5%of neutropenia and 2.1%of diarrhoea *** The current analysis demonstrates comparable efficacy and safety profiles of cetuximab in combination with oral and infusional FP in Chinese *** results expand treatment options for Chinese patients and invite revision of existing treatment guidelines to incorporate oral FP-based chemotherapy plus cetuximab.

关键词： Capecitabine 5-Fluorouracil Cetuximab Metastatic colorectal cancer Chinese

Charge transfer in graphene/polymer interfaces for CO2 detection

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Nano Research 2018年第7期11卷 3529-3536页

作者： Myungwoo Son Yusin pak Sang-Soo Chee Francis Malar Auxilia Kihyeun Kim Byung-Kee Lee Sungeun Lee Sun Kil Kang Chaedeok Lee Jeong Soo Lee Ki Kang Kim Yun Hee Jang Byoung Hun Lee Gun-Young Jung Moon-ho Ham School of Materials Science and Engineering Research Institute for Solar and Sustainable Energies Gwangju Institute of Science & Technology 723 Cheomdangwagi-ro Buk-gu Gwangju 61005 Republic of Korea Materials & Devices Advanced Research Institute LG Electronics Woomyeon R&D Campus 38 Baumoe-ro Seocho-gu Seoul 06763 Republic of Korea Department of Energy and Materials Engineering Dongguk University Seoul 04620 Republic of Korea Energy Systems Engineering Daegu Gyeongbuk Institute of Science & Technology 333 Technojungang-daero Hyeonpung-myeon Dalseong-gun Daegu 42988 Republic of Korea

Understanding charge transfer processes between graphene and functional materials is crucial from the perspectives of fundamental sciences and potential applications, including electronic devices, photonic devices, and sensors. In this study, we present the charge transfer behavior of graphene and amine-rich polyethyleneimine （PEI） upon CO2 exposure, which was significantly improved after introduction of hygroscopic polyethylene glycol （PEG） in humid air. By blending PEI and PEG, the number of protonated amine groups in PEI was remarkably increased in the presence of water molecules, leading to a strong electron doping effect on graphene. The presence of CO2 gas resulted in a large change in the resistance of PEI/PEG-co-functionalized graphene because of the dramatic reduction of said doping effect, reaching a maximum sensitivity of 32% at 5,000 ppm CO2 and an applied bias of 0.1 V in air with 60% relative humidity at room temperature. This charge transfer correlation will facilitate the development of portable graphene-based sensors for real-time gas detection and the extension of the applications of graphene-based electronic and photonic devices.

关键词： graphene polyethyleneimine (PEI) polyethylene glycol carbon dioxide charge transfer

Possibility of Solid Hydrometeor Growth Zone Identification Using Radar Spectrum Width

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Advances in Atmospheric Sciences 2023年第2期40卷 317-332页

作者： Sung-ho SUH Eun-ho ChoI hong-Il KIM Woonseon JUNG Flight Safety Technology Division NARO Space CenterKorea Aerospace Research Institute(KARI)508 Haban-roBongrae-myeonGoheung-gunJeollanam-do 59571Republic of Korea Research Applications Department National Institute of Meteorological Sciences33Seohobuk-roSeoqwipo-siJeju-do 63568Republic of Korea

In this study,the correlation between simulated and measured radar velocity spectrum width(σ_(v))is *** results show that the dendrites growth zones(DGZs)and needles growth zones(NGZs)mostly contain dendrites(DN)and needles(NE),***σ_(v) zones(1.11.2 m s^(-1),a differential reflectivity(ZDR)higher than 0 dB,and a cross-correlation coefficient(ρhv)less than *** contrast,prolate particles with relatively uniform shapes were observed in the NGZ withσ_(v)how that the DN exhibited a largerσ_(v) compared to the NE,and this observedσ_(v) was strongly dependent on the wind fluctuations(v’)due to turbulence or wind *** contrast,the NE exhibited a significantly smallσ_(v)~0.55 m s^(-1),which converges irrespective of v’.In addition,a strong correlation between the measuredσ_(v) values at five radar elevation angles(θ=6.2°,9.1°,13.1°,19°,and 80°)and those simulated in this study confirmed the significance of the analysis results.

关键词： spectrum width weather radar aerodynamic properties dendritic growth zone hydrometeor classifications

SMA molecular line survey towards the massive star-forming region G10.6-0.4in W31complex

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Research in Astronomy and Astrophysics 2018年第11期18卷 29-42页

作者： Wai-ho Wong Tao An Key Laboratory of Radio Astronomy Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China University of Chinese Academy of Sciences Beijing 100049China

Line surveys of complex molecules with millimeter and sub-millimeter telescopes are important for probing the physical and chemical environments of massive star forming regions(MSFRs).We present a molecular line survey with the Submillimeter Array(SMA) in the frequency ranges of 220.3–222.3 GHz and 230.3–232.3 GHz toward G10.6-0.4, the brightest star forming core in the W31 complex. Ninety-nine transitions from 22 molecular species and their isotopologues are identified. The moment 0 images of typical molecules show a compact core which is concentrated at the continuum peak position. Based on the local thermodynamic equilibrium assumption, the molecular line data are modeled. The rotational temperatures of those molecular species range from 96 to 178 K and their column densities range from 2.0×1014to 3.7×1017cm-2. The observational data suggest that all complex molecules are located in a warm environment. Chemical environments of the molecules are discussed. We compared molecular abundances and gas temperatures in G10.6-0.4 with those in other MSFRs, and found that gas temperatures and fractional abundances of specific molecules in G10.6-0.4 are similar to the typical MSFR W51 North, suggesting that there are similar physical and chemical environments in these two MSFRs.

关键词： stars: formation ISM: abundances ISM: individual objects: G10.6-0.4 ISM: molecules radio lines: ISM

Existence results for degenerate p(x)-Laplace equations with Leray-Lions type operators

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Science China Mathematics 2017年第1期60卷 133-146页

作者： ho Ky SIM Inbo Department of Mathematics University of Ulsan Ulsan 680-749 South Korea

We show the existence and multiplicity of solutions to degenerate p(x)-Laplace equations with Leray-Lions type operators using direct methods and critical point theories in Calculus of Variations and prove the uniqueness and nonnegativeness of solutions when the principal operator is monotone and the nonlinearity is nonincreasing. Our operator is of the most general form containing all previous ones and we also weaken assumptions on the operator and the nonlinearity to get the above results. Moreover, we do not impose the restricted condition on p(x) and the uniform monotonicity of the operator to show the existence of three distinct solutions.

关键词： p(x)-Laplacian weighted variable exponent Lebesgue-Sobolev spaces multiplicity a priori bound Leray-Lions type operators

Virtual reconfigurable architecture for evolving combinational logic circuits

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Journal of Central South University 2014年第5期21卷 1862-1870页

作者：王进 LEE Chong-ho Chongqing Key Laboratory of Computational Intelligence(Chongqing University of Posts and Telecommunications) Department of Information&Communication Engineering Inha University

A virtual reconfigurable architecture(VRA)-based evolvable hardware is proposed for automatic synthesis of combinational logic circuits at *** proposed VRA is implemented by a Celoxica RC1000 peripheral component interconnect(PCI)board with an Xilinx Virtex xcv2000E field programmable gate array(FPGA).To improve the quality of the evolved circuits,the VRA works through a two-stage evolution: finding a functional circuit and minimizing the number of logic gates used in a feasible *** optimize the algorithm performance in the two-stage evolutionary process and set free the user from the time-consuming process of mutation parameter tuning,a self-adaptive mutation rate control(SAMRC)scheme is *** the evolutionary process,the mutation rate control parameters are encoded as additional genes in the chromosome and also undergo evolutionary *** efficiency of the proposed methodology is tested with the evolutions of a 4-bit even parity function,a 2-bit multiplier,and a 3-bit *** obtained results demonstrate that our scheme improves the evolutionary design of combinational logic circuits in terms of quality of the evolved circuit as well as the computational effort,when compared to the existing evolvable hardware approaches.

关键词： evolutionary algorithm evolvable hardware self-adaptive mutation rate control virtual reconfigurable architecture

Injury of thalamocortical connection between the mediodorsal nucleus of the thalamus and the orbitofrontal cortex in a patient with traumatic brain injury

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Neural Regeneration Research 2018年第6期13卷 1118-1120页

作者： Sung ho Jang Seong ho Kim Sang Seok Yeo Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Department of Neurosurgery College of Medicine Yeungnam University Department of Physical Therapy College of Health Sciences Dankook University

The prefrontal cortex（PFC）is responsible for personality expression and various cognitive functions,including working memory,recognition memory,decision making,attention,and motivation（Frey and Petrides,2000,2002;M... 详细信息

关键词： TBI OFC DTI MD

Choledochal varices bleeding:A case report

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World Journal of Gastrointestinal Endoscopy 2010年第5期2卷 190-192页

作者： Chi ho Ng Lawrence Lai Ka ho Lok Kin Kong Li Ming leung Szeto Department of Medicine and Geriatrics Tuen Mun HospitalHong KongChina

Choledochal varices are a rare cause of hemobilia associated with chronic portal vein *** present a case of chronic portal vein thrombosis comp licated with bleeding from choledochal *** presentation,clinical manifest... 详细信息

关键词： Bile duct varices Portal hypertens ive biliopathy Common bile duct dilatation Extrahepatic portal vein obstruction Endoscopic ultrasound Hemobilia Portal vein thrombosis

LIOUVILLE RESULTS FOR STABLE SOLUTIONS OF QUASILINEAR EQUATIONS WITH WEIGHTS

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Acta Mathematica Scientia 2019年第2期39卷 357-368页

作者： Phuong LE Vu ho Department of Mathematical Economics Banking University of Ho Chi Minh City Division of Computational Mathematics and Engineering Institute for Computational ScienceTon Duc Thang University Faculty of Mathematics and Statistics Ton Duc Thang University

This paper is devoted to the quasilinear equation ■where p > 2,Ω is a(bounded or unbounded) domain of R^N,w_1,w_2 are nonnegative continuous functions and f is an increasing function. We establish a Liouville type theorem for nontrivial stable solutions of the equation under some mild assumptions on Ω,w_1, w_2 and f, which extends and unifies several results on this topic.

关键词： quasilinear equations stable solutions nonexistence Liouville theorems