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高反光对象表面的结构光三维成像方法

激光与光电子学进展 2019年第5期56卷 125-132页

作者：郑宏博 Yo-Sung ho 刘凯四川大学电气信息学院四川成都610065 韩国光州科技大学电气工程及计算机科学学院韩国光州61005

为了改善高反光对象表面的三维重建的质量,提出了一种基于二值相移编码光栅投影的相位融合算法。该算法对饱和相位误差进行分析,利用二值相移投影图案的周期性与对称性实现了饱和相位误差的检测。研究结果表明,相比于基于光照强度判断... 详细信息

为了改善高反光对象表面的三维重建的质量,提出了一种基于二值相移编码光栅投影的相位融合算法。该算法对饱和相位误差进行分析,利用二值相移投影图案的周期性与对称性实现了饱和相位误差的检测。研究结果表明,相比于基于光照强度判断的饱和误差检测方法,所提方法可以准确检测出存在饱和误差的区域。与修复前相比,修复后的饱和相位误差的均方根值减少了95.7%,最大相位误差减少了96.1%。与传统的检测方法相比,在使用更少测量组的情况下,替换后的饱和相位误差的均方根值减少了16.7%。所提方法可以有效地重建出高反光物体的表面轮廓,且精度更高,无需非线性校正,抗干扰能力强。

关键词：测量相位测量轮廓术二值相移编码光强度饱和相位误差

蛇莓提取物通过GPX4诱导铁死亡抑制肾癌细胞OS-RC-2增殖

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中国药理学通报 2024年第4期40卷 662-670页

作者：游赣花安群英何娟李凯杨萌文周钱城朱建国贵州省第二人民医院科研科贵州贵阳550004 衡水市第六人民医院全科医学科河北衡水053200 贵州中医药大学第二附属医院口腔科贵州贵阳550003 贵阳学院生物与环境工程学院贵州贵阳550005 遵义医科大学研究生院贵州遵义563000 中国人民解放军联勤保障部队第九二五医院质量管理科贵州贵阳550000 贵州省人民医院泌尿外科贵州贵阳550000

目的探讨蛇莓醇提物通过铁死亡抑制肾癌细胞OS-RC-2增殖的作用机制。方法蛇莓醇提物给药,CCK-8试验检测细胞增殖;活性氧(reactive oxygen species,ROS)检测试剂盒、GSH试剂盒、MDA试剂盒、细胞凋亡试剂盒分别检测细胞ROS、GSH、MDA含量... 详细信息

目的探讨蛇莓醇提物通过铁死亡抑制肾癌细胞OS-RC-2增殖的作用机制。方法蛇莓醇提物给药,CCK-8试验检测细胞增殖;活性氧(reactive oxygen species,ROS)检测试剂盒、GSH试剂盒、MDA试剂盒、细胞凋亡试剂盒分别检测细胞ROS、GSH、MDA含量及凋亡水平;网络药理学分析蛇莓成分-靶点;分子对接检测蛇莓成分与铁死亡核心靶点GPX4的结合能力;Western blot对铁死亡信号通路关键蛋白进行检测;利用铁死亡的抑制剂Fer-1和ROS抑制剂NAC进行回复试验,检测细胞增殖及铁死亡蛋白的变化;蛇莓醇提物中的Dulcitol(卫矛醇)给药,检测细胞增殖及GPX4蛋白的变化。结果蛇莓可在一定程度上呈时间-浓度依赖性抑制细胞增殖,显著增加ROS、MDA水平而降低GSH水平;流式细胞术显示蛇莓可显著促进细胞凋亡,但并没有呈浓度依赖方式;网络药理学和分子对接结果显示蛇莓中的卫矛醇与GPX4结合稳定(-6.5 kJ·mol^(-1));Western blot结果显示蛇莓明显降低GPX4、SLC7A11并升高ho-1及Transferrin蛋白水平;回复试验结果显示,Fer-1与蛇莓联合给药、NAC与蛇莓联合给药均可显著逆转蛇莓单独给药引起的细胞活力降低和铁死亡关键蛋白GPX4、SLC7A11、ho-1及Transferrin的蛋白水平变化。卫矛醇给药可抑制OS-RC-2细胞增殖并降低GPX4蛋白表达水平。结论综上所述,蛇莓醇提物可能通过降低GPX4的表达,促使肾癌细胞发生增殖抑制及ROS积累,进一步驱动细胞铁死亡,且卫矛醇可能是蛇莓中潜在的直接作用于GPX4的药效物质。

关键词：蛇莓卫矛醇 OS-RC-2细胞谷胱甘肽过氧化物酶4 活性氧铁死亡

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Catalytic Dehydration of 4-Hydroxy-3-hexanone to 4-Hexen-3-one over HZSM-5 Zeolite

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China Petroleum Processing & Petrochemical Technology 2013年第4期15卷 87-91页

作者： Huang kai Zheng Haitao Tao Keyi School of Environmental and Chemical Engineering Tianjin Polytechnic University Institute of New Catalytic Materials Science College of Chemistry Nankai University

A study on catalytic dehydration of 4-hydroxy-3-hexanone （HH） to 4-hexen-3-one （ho） was carried out through conversion of HH over HZSM-5 zeolite catalyst in a fixed-bed reactor （FBR） operating under almospheric pressure. The test indicated a relatively high activity of the HZSM-5 zeolite capable of achieving a HH conversion of 99.2% and a ho yield of 83.5%. Catalyst deactivation could be prevented by increasing the reaction temperature by 10 ＂C for every 20 h and adding 2.0% of piperidine in the feed. A catalyst stability test （for 100 h） in FBR showed that the catalyst was active even after 100 h of time-on-stream with HH conversion remaining at 99.2% and ho yield still reaching over 83.5%. Regenera- tion experiment showed that the regenerated catalyst demonstrated a catalytic performance comparable to the fresh one.

关键词： HZSM-5 dehydration 4-hydroxy-3-hexanone deactivation regeneration

基于PI3K/Akt/Nrf2信号通路探讨地龙蛋白对自发性高血压大鼠的血管内皮功能保护机制

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中国实验方剂学杂志 2024年第2期30卷 118-126页

作者：赵会林李晓静王丽蓉霍耀辉李赟丁天龙刘凯甘肃中医药大学兰州730000 武威市中医医院甘肃武威733000

目的:观察地龙蛋白对自发性高血压大鼠(SHR)主动脉磷脂酰肌醇3-激酶/蛋白激酶B/核因子E2相关因子2(PI3K/Akt/Nrf2)通路相关因子表达的影响,探讨其治疗高血压血管内皮功能障碍(VED)的作用机制。方法:选取10只10周龄Wistar Kyoto(WKY)大鼠... 详细信息

目的:观察地龙蛋白对自发性高血压大鼠(SHR)主动脉磷脂酰肌醇3-激酶/蛋白激酶B/核因子E2相关因子2(PI3K/Akt/Nrf2)通路相关因子表达的影响,探讨其治疗高血压血管内皮功能障碍(VED)的作用机制。方法:选取10只10周龄Wistar Kyoto(WKY)大鼠及50只SHR适应性喂养1周,WKY大鼠作为正常组,50只SHR按体质量随机分为模型组、缬沙坦组(8×10^(-3) g·kg^(-1)·d^(-1))、地龙蛋白高剂量组(0.2g·kg^(-1)·d^(-1))、地龙蛋白中剂量组(0.1g·kg^(-1)·d^(-1))、地龙蛋白低剂量组(0.05 g·kg^(-1)·d^(-1)),正常组和模型组大鼠用等体积双蒸水灌胃。药物干预期间观察各组大鼠一般情况并分别于给药前及给药后每隔1周特定时间监测大鼠血压。药物干预8周后酶联免疫吸附测定法(ELISA)检测各组大鼠血清中血管紧张素-Ⅱ(Ang-Ⅱ)、内皮素-1(ET-1)活性水平;生化试剂盒法检测一氧化氮(NO)、丙二醛(MDA)、谷胱甘肽过氧化物酶(GPX)水平,超氧化物歧化酶(SOD)活性、亚铁离子(Fe2+)浓度;苏木素-伊红(HE)染色观察主动脉内膜变化情况;实时荧光定量聚合酶链式反应(Real-time PCR)检测主动脉组织PI3K、Akt、Nrf2、血红素加氧酶1(ho-1)、谷胱甘肽过氧化物酶4(GPX4)mRNA表达情况;蛋白免疫印迹法(Western blot)检测胸主动脉中p-PI3K(Tyr467/199)、PI3K、p-Akt(Ser473)、Akt、Nrf2、ho-1、GPX4蛋白表达水平。结果:与正常组比较,模型组大鼠体质量偏低,大鼠较烦躁易激惹,内皮损伤程度较重;模型组大鼠血压、血清Ang-Ⅱ、ET1、MDA、Fe2+均显著升高(Pho-1、GPX4蛋白及mRNA表达显著降低(Pho-1、GPX4蛋白及mRNA表达明显升高(P<0.05)。结论:地龙蛋白可通过改善SHR内皮功能障碍起到降压作用,其机制可能与调控PI3K/Akt/Nrf2相关信号通路、抑制氧化应激及铁死亡相关。

关键词：地龙蛋白自发性高血压大鼠内皮功能障碍氧化应激铁死亡磷脂酰肌醇3-激酶/蛋白激酶B/核因子E2相关因子2(PI3K/Akt/Nrf2)信号通路

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High-performance (NH_(4))_(2)V_(6)O_(16).0.9H_(2)O nanobelts modified with reduced graphene oxide for aqueous zinc ion batteries

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Chinese Chemical Letters 2021年第12期32卷 3793-3798页

作者： Fang Hu Yao Gu Fuhan Cui Guihong Song kai Zhu School of Materials Science and Engineering Shenyang University of TechnologyShenyang 110870China Key Laboratory of Superlight Materials and Surface Technology of Ministry of Education College of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150010China Department of Mechanical Engineering the Hong Kong Polytechnic UniversityHong Kong 999077China

Ammonium vanadate has been considered as a competitive high-performance cathode material for aqueous Zn-ion ***,it still suffers from insufficient rate capability and poor cyclability due to the low electronic ***,(NH_(4))_(2)V_(6)O_(16).0.9H_(2)Onanobelts with reduced graphene oxide(RGO)modification are synthesized by one-step hydrothermal *** from the addition of RGO,an excellent electrochemical performance of(NH_(4))_(2)V_(6)O_(16).0.9H_(2)O@RGO nanobelts can be ***(NH_(4))_(2)V_(6)O_(16).0.9H_(2)O@RGO displays a high-rate capacity and a high energy density of 386 Wh/kg at 72 W/*** particular,after 1000 cycles at 5 A/g,the capacity remains at 322 mAh/g with 92.8%capacity *** addition,the key reaction mechanisms of reversible Zn^(2+)insertion/extraction in(NH_(4))_(2)V_(6)O_(16).0.9H_(2)O@RGO are clarified.

关键词： (NH_(4))_(2)V_(6)O_(16).0.9H_(2)O@RGO Nanobelts Aqueous Zn-ion batteries Electrochemical performance Reaction mechanism

Gasification of iron coke and cogasification behavior of iron coke and coke under simulated hydrogen-rich blast furnace condition

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International Journal of Minerals,Metallurgy and Materials 2022年第10期29卷 1839-1850页

作者： kai Zhu Zhuming Chen Shuixin Ye Shuhua Geng Yuwen Zhang Xionggang Lu State Key Laboratory of Advanced Special Steel&Shanghai Key Laboratory of Advanced Ferrometallurgy&School of Materials Science and Engineering Shanghai UniversityShanghai 200444China

To explore the iron coke application in hydrogen-rich blast furnace,which is an effective method to achieve the purpose of low carbon emissions,the initial gasification temperature of iron coke in CO_(2) and H_(2)O atmosphere and its cogasification reaction mechanism with coke were systematically *** coke was prepared under laboratory conditions,with a 0-7wt%iron ore powder *** properties of iron cokes were tested by coke reactivity index(CRI)and coke strength after reaction(CSR),and their phases and morphology were evolution discussed by scanning electron microscopy and X-ray diffraction *** results indicated that the initial gasification temperature of iron coke decreased with the increase in the iron ore powder content under the CO_(2) and H_(2)O_((g))*** the 40vol%H_(2)O+60vol%CO_(2) atmosphere,CRI of iron coke with the addition of 3wt%iron ore powder reached 58.7%,and its CSR reached 56.5%.Because of the catalytic action of iron,the reaction capacity of iron coke was greater than that of *** iron coke was preferentially gasified,the CRI and CSR of coke were reduced and increased,respectively,when iron coke and coke were *** results showed that the skeleton function of the coke can be protected by iron coke.

关键词： iron coke hydrogen-rich blast furnace coke gasification coke reactivity index coke strength after reaction

A New Code Family for Double Spread Transmissions in Radio-over-Fiber over Optical CDMA Network

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通讯和计算机（中英文版） 2016年第7期13卷 366-372页

作者： kai-Sheng Chen Chao-Chin Yang Jen-Fa Huang Hsuan-ho Chang Institute of Computer and Communication Engineering Department of Electrical Engineering National Chen Kung University. No. 1 University Rd. East Dist. Tainan Taiwan Department of Electro-Optical Engineering Kun Shan University. No. 195 Kunda Rd. Yongkang Dist. Tainan Taiwan

An unprecedented outbreak investigation for nosocomial and community-acquired legionellosis in hong Kong

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Chinese Medical Journal 2012年第23期125卷 4283-4290页

作者： CHENG Vincent Chi-chung WONG Samson Sai-yin CHEN Jonathan hon-kwan CHAN Jasper Fuk-woo TO Kelvin kai-wang POON Rosana Wing-shan WONG Sally Cheuk-ying CHAN Kwok-hung TAI Josepha Wai-ming ho Pak-leung TSANG Thomas ho-fai YUEN Kwok-yung Department of Microbiology Queen Mary Hospital Hong Kong China Infection Control Team Queen Mary Hospital Hong Kong China Centre for Health Protection Department of Health Hong Kong China

Background The environmental sources associated with community-acquired or nosocomial legionellosis were not always detectable in the mainland of China and hong Kong, China. The objective of this study was to illustrate the control measures implemented for nosocomial and community outbreaks of legionellosis, and to understand the environmental distribution of legionella in the water system in hong Kong, China. Methods We investigated the environmental sources of two cases of legionellosis acquired in the hospital and the community by extensive outbreak investigation and sampling of the potable water system using culture and genetic testing at the respective premises. Results The diagnosis of nosocomial legionellosis was suspected in a patient presenting with nosocomial pneumonia not responsive to multiple beta-lactam antibiotics with subsequent confirmation by Legionella pneumophila serogroup 1 antigenuria. High counts of Legionella pneumophila were detected in the potable water supply of the 70-year-old hospital building. Another patient on continuous ambulatory peritoneal dialysis presenting with acute community-acquired pneumonia and severe diarrhoea was positive for Legionella pneumophila serogroup 1 by polymerase chain reaction （PCR） testing on both sputum and nasopharyngeal aspirate despite negative antigenuria. Paradoxically the source of the second case was traced to the water system of a newly commissioned office building complex. No further cases were detected after shock hyperchlorination with or without superheating of the water systems. Subsequent legionella counts were drastically reduced. Point-of-care infection control by off-boiled or sterile water for mouth care and installation of water filter for showers in the hospital wards for immunocompromised patients was instituted. Territory wide investigation of the community potable water supply showed that 22.1% of the household water supply was positive at a mean legionella count of 108.56 CFU/ml （rang

关键词： outbreak nosocomial legionellosis community-acquired legionellosis

Cerium and ruthenium co-doped La_(0.7)Sr_(0.3)FeO_(3-δ) as a high-efficiency electrode for symmetrical solid oxide fuel cell

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Journal of Rare Earths 2021年第9期39卷 1095-1099页

作者： Junkai Wang Lei Fu Jiaming Yang Ke Wu Jun Zhou kai Wu Center of Nanomaterials for Renewable Energy State Key Laboratory of Electrical Insulation and Power EquipmentXi'an Jiaotong UniversityXi'an710049China

Symmetrical solid oxide fuel cells(SSOFCs)could be alternative energy conversion devices due to their simple fabrication process and low ***,perovskite La_(0.6)Ce_(0.1)Sr_(0.3)Fe_(0.95)Ru_(0.05O3-δ)(LCSFR)was synthesized and evaluated as a high-performance electrode for SSOFCs based on the electrolyte of La_(0.9)Sr_(0.1)Ga_(0.8)Mg_(0.2)O_(3-δ)(LSGM).LCSFR retains their stable perovskite crystal structure in both reducing and oxidizing atmospheres,though a minor amount of LaSrFeO4 phase is present under reducing *** investigation shows that homogeneously dispersed Ru metallic nanoparticles are exsolved on the surface of LCSFR after being *** polarization resistance(Rp)of LCSFR-CGO(Ce_(0.9)Gd_(0.1O2-δ))is about 0.11Ω·cm^(2)at 800℃in air,while the value of Rp for LCSFR-CGO in wet H_(2)(3%H_(2)O)increases up to 0.32Ω·cm^(2).The symmetrical LCSFR-CGOILSGMILCSFR-CGO cell demonstrates a performance with an open circuit potential(OCV)of 1.07 V and a maximum peak power density of 904 mW/cm^(2)at 800℃using wet H2 as the *** high performance indicates that LCSFR is a candidate electrode for SSOFCs.

关键词： Symmetrical electrode SSOFCs Exsolution Nanoparticle catalysts Rare earths