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Enhancement of pre-pulse and picosecond pedestal contrast of the petawatt J-KAREN-P laser

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High Power Laser Science and Engineering 2021年第4期9卷 192-199页

作者： hiromitsu kiriyama Yasuhiro Miyasaka Akira Kon Mamiko Nishiuchi Akito Sagisaka Hajime Sasao Alexander S.Pirozhkov Yuji Fukuda Koichi Ogura Kotaro Kondo Nicholas P.Dover Masaki Kando Kansai Photon Science Institute National Institutes for Quantum Science and Technology(QST)Kizugawa 619-0215Japan Naka Fusion Institute National Institutes for Quantum Science and Technology(QST)Naka 311-0193Japan

We have experimentally improved the temporal contrast of the petawatt J-KAREN-P laser *** have investigated how the generation of pre-pulses by post-pulses changes due to the temporal overlap between the stretched pulse and the post-pulse in a chirped-pulse amplification *** have shown that the time at which the pre-pulse is generated by the post-pulse and its shape are related to the time difference between the stretched main pulse and the *** this investigation,we have found and identified the origins of the pre-pulses and have demonstrated the removal of most pre-pulses by eliminating the post-pulse with wedged *** have also demonstrated the impact of stretcher optics on the picosecond *** have realized orders of magnitude enhancement of the pedestal by improving the optical quality of a key component in the stretcher.

关键词： chirped-pulse amplification temporal contrast ultra-high-intensity lasers

High-intensity laser-driven particle and electromagnetic wave sources for science, industry, and medicine

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Frontiers of Optoelectronics 2009年第3期2卷 299-303页

作者： Akito SAGISAKA Hiroyuki DAIDO Alexander S.PIROZHKOV Michiaki MORI Akifumi YOGO Koichi OGURA Satoshi ORIMO Mamiko NISHIUCHI Jinglong MA hiromitsu kiriyama Shuhei KANAZAWA Shuji KONDO Yoshiki NAKAI Takuya SHIMOMURA Manabu TANOUE Atsushi AKUTSU Hajime OKADA Tomohiro MOTOMURA Tetsuya KAWACHI Sergei V.BULANOV Timur Zh.ESIRKEPOV Shigeki NASHIMA Makoto HOSODA Hideo NAGATOMO Yuji OISHI Koshichi NEMOTO Il Woo CHOI Seong Ku LEE Jongmin LEE Advanced Photon Research Center and Photo-Medical Research Center Japan Atomic Energy Agency A.M.Prokhorov Institute of General Physics Russian Academy of Sciences Moscow Institute of Physics and Technology Department of Applied Physics Graduate School and Faculty of Engineering Osaka City University Institute of Laser Engineering Osaka University Central Research Institute of Electric Power Industry Advanced Photonics Research Institute Gwangju Institute of Science and Technology

We simultaneously observed both the fast proton generation and terahertz(THz) radiation in the laser pulse interaction with a thin-foil target. The maximum proton energy of ～2.3 Me V and an intense THz radiation were observed at the pulse duration of～30 fs. We also measured the proton beam and UV harmonics from a thin-foil target by changing the laser pulse duration. In the case of the ～500 fs, peaks of UV harmonics up to fourth order appeared. This unique combination of the multiple beams will provide useful applications such as pump-probe experiments.

关键词： high-intensity laser thin-foil target plasma proton electromagnetic wave

Enhanced ion acceleration from transparency-driven foils demonstrated at two ultraintense laser facilities

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Light(Science & Applications) 2023年第4期12卷 593-604页

作者： Nicholas P.Dover Tim Ziegler Stefan Assenbaum Constantin Bernert Stefan Bock Florian-Emanuel Brack Thomas E.Cowan Emma J.Ditter Marco Garten Lennart Gaus Ilja Goethel George S.Hicks hiromitsu kiriyama Thomas Kluge James K.Koga Akira Kon Kotaro Kondo Stephan Kraft Florian Kroll Hazel F.Lowe Josefine Metzkes-Ng Tatsuhiko Miyatake Zulfikar Najmudin Thomas Püschel Martin Rehwald Marvin Reimold Hironao Sakaki Hans-Peter Schlenvoigt Keiichiro Shiokawa Marvin E.P.Umlandt Ulrich Schramm Karl Zeil Mamiko Nishiuchi Kansai Photon Science Institute National Institutes for Quantum Science and Technology8-1-7 UmemidaiKizugawaKyoto 619-0215Japan The John Adams Institute for Accelerator Science Blackett LaboratoryImperial College LondonLondon SW72AZUnited Kingdom Helmholtz-Zentrum Dresden-Rossendorf 01328 DresdenGermany Technische Universitat Dresden 01069 DresdenGermany Interdiscipllinary Graduate School of Engineering Sciences Kyushu University6-1Kasuga-KoenKasugaFukuoka 816-8580Japan

Laser-driven ion sources are a rapidly developing technology producing high energy,high peak current *** suitability for applications,such as compact medical accelerators,motivates development of robust acceleration schemes using widely available repetitive ultraintense femtosecond *** applications not only require high beam energy,but also place demanding requirements on the source stability and *** can be seriously affected by the laser temporal contrast,precluding the replication of ion acceleration performance on independent laser systems with otherwise similar ***,we present the experimental generation of>60 MeV protons and>30 MeV u-1 carbon ions from sub-micrometre thickness Formvar foils irradiated with laser intensities>1021 *** are accelerated by an extreme localised space charge field≥30TVm-1,over a million times higher than used in conventional *** field is formed by a rapid expulsion of electrons from the target bulk due to relativistically induced transparency,in which relativistic corrections to the refractive index enables laser transmission through normally opaque *** replicate the mechanism on two different laser facilities and show that the optimum target thickness decreases with improved laser contrast due to reduced *** demonstration that energetic ions can be accelerated by this mechanism at different contrast levels relaxes laser requirements and indicates interaction parameters for realising application-specific beam delivery.

关键词： acceleration intense transparency

Propofol sedation during endoscopic treatment for early gastric cancer compared to midazolam

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World Journal of Gastroenterology 2014年第34期20卷 11985-11990页

作者： Shinsuke kiriyama Hiroshi Naitoh Hiroyuki Kuwano Department of Surgery Gunma Chuo General HospitalMaebashiGunma 371-0025Japan Department of General Surgical Science Graduate School of MedicineGunma UniversityGunma 371-0025Japan

Endoscopic submucosal dissection(ESD)has been proposed as the gold standard in the treatment of early gastric cancer because it facilitates a more accurate histological assessment and reduces the risk of tumor ***,the time course of ESD for large gastric tumors is frequently prolonged because of the tumor size and technical difficulties and typically requires higher doses of sedative and pain-controlling *** or anesthetic drugs such as midazolam or propofol are used during the *** endoscopy of early gastric cancers can often be performed with only moderate *** with midazolam,propofol has a very fast onset of action,short plasma half-life and time to achieve sedation,faster time to recovery and discharge,and results in higher patient *** overall success,maintaining safety and stability not only during the procedure but also subsequently in the recovery room and ward is *** obese patients,it is recommended that the injected dose be based on a calculated standard *** between gastroenterologists,surgeons,and anesthesiologists is imperative for a successful ESD procedure.

关键词： Sedation Gastric cancer Endoscopic submucosal dissection Endoscopic resection Propofol

HOT WIRE MEASUREMENT OF TURBULENT BOUNDARY LAYER ON A FILM COOLING PLATE WITH DIFFUSION HOLES

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Journal of Hydrodynamics 2001年第2期13卷 15-23页

作者： Shi, H.H. kiriyama, K. Itoh, M. Dept. of Mechanics Zhejiang Univ. Hangzhou 310027 China

This study experimentally investigated the film cooling flowfield of a single row of diffusion holes, from which the secondary air flow was injected into a turbulent boundary layer with zero pressure gradient on a flat plate. Circular-shaped holes were also tested as a basis for comparison. All the holes were inclined downstream at 35° with respect to the surface and the lateral spacing between the holes was 3 diameters of the hole. The mainstream velocity was maintained at 17 m/s and the Reynolds number based on the injection hole diameter was almost 11000. The density ratio of the jet to mainstream was 1.0, and the jet-to-mainstream velocity ratios M were 0.5 and 1.5. Normal-type and X-type hot wire anemometries were used to measure the streamwise mean velocity and its components, the normal and shear turbulent Reynolds stress components at the locations from the backward edge of the injection hole to 25 diameters downstream.

关键词： Boundary layer flow Cooling Turbulent flow Vectors Velocity Wind tunnels

Endoscopic papillectomy of minor papillar adenoma associated with pancreas divisum

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World Journal of Gastroenterology 2009年第9期15卷 1138-1140页

作者： Akira Kanamori Takashi Kumada Seiki kiriyama Yasuhiro Sone Makoto Tanikawa Yasuhiro Hisanaga Hidenori Toyoda Hiroki Kawashima Akihiro Itoh Yoshiki Hirooka Hidemi Goto Department of Gastroenterology Ogaki Municipal HospitalOgaki 503-8502Japan Department of Gastroenterology Nagoya University Graduate School ofMedicineNagoya 466-8560Japan Department of Gastroenterology Nagoya University Graduate School of MedicineNagoya 466-8560Japan Department of Endoscopy Nagoya University HospitalNagoya 466-8560Japan

Tumors of the minor papilla of the duodenum are quite *** successfully and safely treated an 18-mm adenoma of the minor papilla associated with pancreas divisum using endoscopic papillectomy.A 64-year-old man was admitted to our hospital for treatment of an asymptomatic mass in the minor papilla detected by upper gastrointestinal *** analysis showed an 18-mm,whitish,sessile mass,located in the duodenum proximal to a normal-appearing major *** retrograde pancreatography did not reveal the pancreatic *** resonance cholangiopancreatography showed a lack of the ventral pancreatic *** suspected this case was associated with pancreatic divisum;therefore,we performed endoscopic papillectomy of the minor papilla ***,endoscopic pancreatic stent placement in the minor papilla was done to prevent drainage *** patient has been asymptomatic without recurrence of tumor or stenosis of the Santorini orifice upon endoscopic examination for the past 2 years.

关键词： Endscopic papitlectomy Minor papill aradenoma Pancreas divisum Endoscopic pancreatic stent Endoscopic retrograde pancreatography

Effect of Diffusively Shaped Holes on the Turbulent Flow Field of a Film Cooling Plate

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Chinese Journal of Aeronautics 2002年第1期15卷 6-11页

作者：施红辉桐山贤司伊藤基之 Department of Mechanics Zhejiang University Hangzhou 310027 China Department of Mechanical Engineering Nagoya Institute of Technology Nagoya 466-8555 Japan

The gas turbine blades with diffusion film cooling holes are newlydeveloped blade struc- tures in the hydrogen combustion gas turbine,which has an extremely high inlet gas temperature (1700 deg. C). TheFluid Machinery Laboratory of Nagoya Institute o Technology conductedfirstly a new research o the turbulent flow field over the gasturbine blade with diffusion film cooling holes in Japan. Normal-typeand X-ray hot wires were applied in the measurement of the flowfield.

关键词： turbulent boundary layer film cooling diffusion hole hot wireanemometry

Metrology for sub-Rayleigh-length target positioning in ～1022W/cm2 laser-plasma experiments

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High Power Laser Science and Engineering 2024年第3期 95-110页

作者： E.A.Vishnyakov A.Sagisaka K.Ogura T.Zh.Esirkepov B.Gonzalez-Izquierdo C.D.Armstrong T.A.Pikuz S.A.Pikuz W.Yan T.M.Jeong S.Singh P.Hadjisolomou O.Finke G.M.Grittani M.Nevrkla C.M.Lazzarini A.Velyhan T.Hayakawa Y.Fukuda J.K.Koga M.Ishino K.Kondo Y.Miyasaka A.Kon M.Nishikino Y.V.Nosach D.Khikhlukha I.P.Tsygvintsev D.Kumar J.Nejdl D.Margarone P.V.Sasorov S.Weber M.Kando H.kiriyama Y.Kato,G.Korn K.Kondo S.V.Bulanov T.Kawachi A.S.Pirozhkov ELI Beamlines Facility The Extreme Light Infrastructure ERIC Kansai Institute for Photon Science (KPSI) Central Laser Facility Rutherford Appleton LaboratorySTFC Institute for Open and Transdisciplinary Research Initiatives Osaka University HB11 Energy Holdings Key Laboratory for Laser Plasmas (Ministry of Education) School of Physics and AstronomyShanghai Jiao Tong University Collaborative Innovation Center of IFSA Shanghai Jiao Tong University Institute of Plasma Physics ASCR FZU±Institute of Physics ASCR Czech Technical University in Prague Institute of Laser Engineering Osaka University Institute of Physics National Academy of Sciences of Ukraine ISTEQ AR

Tight focusing with very small f-numbers is necessary to achieve the highest at-focus ***,tight focusing imposes strong demands on precise target positioning in-focus to achieve the highest on-target irradiance We describe several near-infrared,visible,ultraviolet and soft and hard X-ray diagnostics employed in a～1022W/cm2laser±plasma *** used nearly 10 J total energy femtosecond laser pulses focused into an approximately1.3-μm focal spot on 5±20μm thick stainless-steel *** discuss the applicability of these diagnostics to determine the best in-focus target position with approximately 5μm accuracy （i.e.,around half of the short Rayleigh length）and show that several diagnostics （in particular,3ωreflection and on-axis hard X-rays） can ensure this *** demonstrated target positioning within several micrometers from the focus,ensuring over 80%of the ideal peak laser intensity *** approach is relatively fast （it requires 10±20 laser shots） and does not rely on the coincidence of low-power and high-power focal planes.

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CT冠状动脉造影联合负荷心肌灌注显像用于慢性冠心病患者危险度分层的可行性

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中华核医学与分子影像杂志 2018年第7期38卷 516-516页

作者：唐军 Tomonari kiriyama Yoshimitsu Fukushima hiromitsu Hayashi Hitoshi Takano Shin-ichiro Kumita 上海交通大学医学院附属苏州九龙医院核医学科 Department of Radiology Graduate School of RadiologyNippon Medical School

目的研究可疑或已知冠心病患者CT冠状动脉造影(CTA)相对心肌灌注显像(MPI)在预后预测上的增益价值。方法 157例患者[平均年龄(69±9)岁,男性占76%,中位随访时间49(12～82)个月]间隔6个月内行负荷MPI和CTA。记录并分析负荷MPI的总负荷分... 详细信息

目的研究可疑或已知冠心病患者CT冠状动脉造影(CTA)相对心肌灌注显像(MPI)在预后预测上的增益价值。方法 157例患者[平均年龄(69±9)岁,男性占76%,中位随访时间49(12～82)个月]间隔6个月内行负荷MPI和CTA。记录并分析负荷MPI的总负荷分值(SSS)、总差分值(SDS),CTA所见狭窄冠状动脉数及是否有左主干狭窄和高危斑块。首要终止事件包括心源性死亡、急性心肌梗死或不稳定性心绞痛需要血管重建,次要终止事件为MPI或CTA后60 d内行血管重建。结果 9例(6%)患者发生首要终止事件,其中心源性死亡1例(0.6%)、心肌梗死5例(3%)、不稳定性心绞痛住院治疗3例(2%)。31例(20%)患者MPI或CTA后60 d内行选择性血管重建。16例(10%)患者MPI或CTA 60 d后行血管重建。未发生首要终止事件患者的生存率低于心肌缺血(SDS≥2)患者、高危斑块(HRP)患者和未发生次要终止事件的SSS≥4及3VD患者的生存率。在多因素分析中,Cox比例风险回归分析发现HRP[风险比(HR)=11.487,P=0.025]和心肌缺血(HR=11.487,P=0.025)是首要终止事件的预测因子,而3VD(HR=4.981,P=0.008)是次要终止事件的预测因子。心肌缺血合并HRP预测首要终止事件优于心肌缺血或HRP单独预测(17.4与9.41,P=0.005;17.4与9.39,P=0.005)。结论 CTA相对MPI也许能提供更多的预后信息。

关键词：心肌灌注显像 CT冠状动脉造影危险度分层冠心病缺血性心脏病