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Optimum Dark Adaptation Period for Evaluating the Maximum Quantum Efficiency of Photosystem II in Ozone-Exposed Rice Leaves

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American Journal of Plant Sciences 2013年第9期4卷 1750-1757页

作者： hiroki hiroki kobayakawa Katsu Imai School of Agriculture Meiji University Kawasaki Japan.

Because the transient O3 injury of leaves is lost with time, the evaluation of O3 effect on the maximum quantum efficiency of PSII (Fv/Fm) is difficult. Thus, the authors examined Fv/Fm in rice leaves exposed to different O3 concentrations (0, 0.1, and 0.3 cm3·m-3, expressed as O0, O0.1, and O0.3) under different dark adaptation periods (0, 1, 5, 10, 20, and 30 min, expressed as D0, D1, D5, D10, D20, and D30) to ascertain its optimum time span. Fv/Fm was inhibited by O3;however in the O0 and O0.1 plants, it recovered during dark adaptation. In the O0.3 plants, Fv/Fm decreased gradually with time. F0 was found to be increased by O3, and it increased further in the O0.3 plants during dark adaptation. Under a high light intensity, Fm was decreased by O3, and the O3-induced damage to Fv/Fm was therefore more pronounced. However, the sensitivity of

关键词： Dark-Adapted State Oryza sativa Ozone Stress Photosystem II Quantum Efficiency

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Predictive findings forHelicobacter pylori-uninfected, -infected and -eradicated gastric mucosa: Validation study

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World Journal of Gastroenterology 2013年第27期19卷 4374-4379页

作者： Kazuhiro Watanabe Naoyoshi Nagata Ryo Nakashima Etsuko Furuhata Takuro Shimbo Masao kobayakawa Toshiyuki Sakurai Koh Imbe Ryota Niikura Chizu Yokoi Junichi Akiyama Naomi Uemura Department of Gastroenterology and Hepatology National Center for Global Health and Medicine Department of Clinical Research and Informatics National Center for Global Health and Medicine Department of Gastroenterology and Hepatology National Center for Global Health and MedicineKohnodai Hospital

AIM:To validate the usefulness of screening endoscopy findings for predictingHelicobacter pylori (H. pylori) infection status. METHODS:H. pylori infection status was determined by histology, serology, and the urea breast test in 77 consecutive patients who underwent upper endoscopy. Based on the findings, patients were categorized as H. pylori -uninfected, -infected, or -eradicated cases. Using six photos of certain sites in the stomach per case, we determined the presence or absence of the following endoscopic findings:regular arrangement of collecting venules (RAC), linear erythema, hemorrhage, fundic gland polyp (FGP), atrophic change, rugal hyperplasia, edema, spotty erythema, exudate, xanthoma, and mottled patchy erythema (MPE). The diagnostic odds ratio (DOR) and inter-observer agreement (Kappa value) for these 11 endoscopic findings used in the determination of H. pylori infection status were calculated. RESULTS:Of the 77 patients [32 men and 45 women; mean age (SD), 39.7 (13.4) years] assessed, 28 were H. pylori uninfected, 28 were infected, and 21 were eradicated. DOR values were significantly high (< 0.05) for the following H. pylori cases:uninfected cases with RAC (11.5), linear erythema (24.5), hemorrhage (4.1), and FGP (34.5); for infected cases with atrophic change (8.67), rugal hyperplasia (15.8), edema (14.2), spotty erythema (11.5), and exudate (3.52); and for eradicated cases with atrophic change (32.4) and MPE (103.0). Kappa values were excellent for FGP (0.93), good for RAC (0.63), hemorrhage (0.79), atrophic change (0.74), and MPE (0.75), moderate for linear erythema (0.51), rugal hyperplasia (0.49), edema (0.58), spotty erythema (0.47), and exudate (0.46), and poor for xanthoma (0.19). CONCLUSION:The endoscopic findings of RAC, hemorrhage, FGP, atrophic change, and MPE will be useful for predicting H. pylori infection status.

关键词： Diagnostic odds ratio Endoscopic finding Eradication therapy Helicobacter pylori Inter-observer agreement

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3D-ComFutaional Mesh Generation around a Propeller by Elliptic Differential Equation System

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航空动力学报 1988年第1期 81-86页

作者： MakotokobayakawaandIchiroHATANO Kyoto University

In this paper, an analytic method is applied for the generation of 3D mesh system in order for Navier-Stokes equations around ATP (Propfan). One of the advantages of this method is that mesh lines have strong differentiability. The differential equation used is Poisson type and the right hand side is called control function, and this is able to control the degree of mesh line clustering. Here, the form of control function was contrived to cluster near the solid surfaces. By this method, several mesh lines are laid in the boundary layer above the blade surfaces.

关键词： line Mesh ComFutaional Mesh Generation around a Propeller by Elliptic Differential Equation System

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Diagnostic value of antigenemia assay for cytomegalovirus gastrointestinal disease in immunocompromised patients

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World Journal of Gastroenterology 2011年第9期17卷 1185-1191页

作者： Naoyoshi Nagata Masao kobayakawa Takuro Shimbo Kazufusa Hoshimoto Tomoyuki Yada Takuji Gotoda Junichi Akiyama Shinichi Oka Naomi Uemura Department of Gastroenterology and Hepatology National Center for Global Health and Medicine Department of Clinical Research and Informatics International Clinical Research Center Research Institute National Center for Global Health and Medicine Department of Clinical Laboratory Pathological Division National Center for Global Health and Medicine Department of Gastroenterology and Hepatology National Center for Global Health and MedicineKohnodai Hospital Division of Aids Clinical Center National Center for Global Health and Medicine

AIM:To investigate the utility of the cytomegalovirus(CMV)antigenemia assay for the diagnosis of CMV gastrointestinal disease(GID). METHODS:One hundred and thirty immunocompromised patients were enrolled in this *** with a history of anti-CMV treatment and who had not undergone examination using the antigenemia assay were ***-GID was defined as the detection of large cells with intranuclear inclusions alone or associated with granular cytoplasmic inclusions by *** sections were stained with hematoxylin and eosin and immunohistochemically stained with *** evaluated the association between CMV-GID and patient characteristics(symptoms,underlying disease,medication,leukocyte counts,and antigenemia assay).All patients were checked with an human immunodeficiency virus(HIV)antibody test before endoscopic *** blood cell(WBC)counts were obtained from medical records within 1 wk of *** was defined as a total WBC count<5000 cells/mm 3 . For HIV patients,we also checked CD4+counts from medical records. RESULTS:A total of 99 patients were retrospectively selected for *** the immunocompromised patients,19 had malignant disease,18 had autoimmune disease,19 had disorders of biochemical homeostasis, three had undergone transplantation,and 45 had HIV infection.A total of 50 patients had received immunosuppressive *** patients had inflammatory bowel ***-five patients were diagnosed as having *** analysis indicated an association between HIV infection,leukopenia,and positive antigenemia and CMV-GID(P<0.05).Multivariate analysis using logistic regression revealed that HIV infection and positive antigenemia were the only independent factors related to CMV-GID(P<0.01).The sensitivity,specificity,positive predictive value,and negative predictive value of antigenemia for CMV-GID were 65.4%,93.6%, 91.9%,and 71.0%,*** a subgroup analy-sis,patients with leukopenia displayed

关键词： Cytomegalovirus Gastrointestinal disease Antigenemia assay Real-time polymerase chain reaction Human immunodeficiency virus infection

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老鼠爱上猫

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小哥白尼（趣味科学） 2008年第10期 24-26页

作者：乒乒 Ko & Reiko kobayakawa

大家好!我叫杰瑞,是一只可爱的小灰鼠。"什么,你竟然说我不可爱?"我可是出身名门:大哥米老鼠,是人人皆知的大明星;二哥是厨师,在电影《料理鼠王》中当主角;三哥聪明勇敢,被人类称为"精灵鼠小弟";我虽然天生胆小懦弱,有时还"

关键词：人类气味能力手术刀食物发现维生医生基因工程提供

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