检索结果-南通市图书馆

Recent trends in bone metastasis treatments:A historical comparison using the new Katagiri score system

World Journal of Clinical Cases 2024年第15期12卷 2499-2505页

作者： Kenji Matsuda Kazuhiro Shimazu Hanae Shinozaki Koji fukuda Taichi Yoshida Daiki Taguchi Kyoko Nomura Hiroyuki Shibata Department of Clinical Oncology Akita University Graduate School of MedicineAkita 010-8543Japan Department of Environmental Health Science and Public Health Akita University Graduate School of MedicineAkita 010-8543Japan Department of Comprehensive Cancer Control Akita University Graduate School of MedicineAkita 010-8543Japan

BACKGROUND Bone metastasis has various negative *** of daily living(ADL)and quality of life(QOL)can be significantly decreased,survival may be impacted,and medical expenses may *** is estimated that at least 5%cancer patients might be suffering from bone *** 2016,we published the Comprehensive Guidelines for the Diagnosis and Treatment of Bone *** then,the therapeutic outcomes for patients have gradually *** life expectancy is a major determinant of surgical intervention,the strategy should be modified if the prolongation of survival is to be *** To monitor how bone metastasis treatment has changed before and after launch of our guidelines for bone *** For advanced cancer patients with bone metastasis who visited the Department of Clinical Oncology at Akita University hospital between 2012 and 2023,parameters including the site and number of bone metastases,laboratory data,and survival time,were extracted from electronic medical records and the Katagiri score was *** association with survival was determined for each *** Data from 136 patients were *** 1-year survival rate for the poor prognosis group with a higher Katagiri score was 20.0%in this study,which was 6%and an apparent improvement from 2014 when the scoring system was *** factors significantly affecting survival included five or more bone metastases than less(P=0.0080),and treatment with chemotherapy(P<0.001),bone modifying agents(P=0.0175)and immune checkpoint inhibitors(P=0.0128).In recent years,advances in various treatment methods have extended the survival period for patients with advanced *** is necessary not only to simply extend survival time,but also to maintain ADL and improve *** Various therapeutic interventions including surgical approach for bone metastasis,which is a disorder of locomotor organs,are increasingly *** and scoring system for p

关键词： Bone metastasis New Katagiri scoring system Prognosis Immune check point inhibitors Survival

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Shot lining of magnesium alloy with hard powders

引用

Transactions of Nonferrous Metals Society of China 2010年第B7期20卷 708-712页

作者： Y.HARADA I.fukuda Graduate School of Engineering University of Hyogo Yatsushiro National College of Technology

To improve the surface properties,lining of magnesium alloys with hard powders by shot peening was carried out in order. The hard powders were tried to bond to the workpiece surface due to the collision of many *** order to fix the hard powders to the surface of the workpiece,the powders were set on an uneven *** easily facilitate fixing of powders,lining of the workpiece with the powder sandwiched between two aluminum foil sheets was also *** this experiment,a centrifugal shot peening machine with an electrical heater was *** workpieces were magnesium alloys AZ31B and AZ91D,and the hard powders were commercial cemented carbide,alumina,and *** joinability of hard powders near the lined surface was observed by a optical *** wear resistance was also evaluated by a wear *** hard powders were successfully bonded to the surface of workpieces by the shot lining *** results show that the present method is effective in wear resistance of the magnesium alloys.

关键词： shot peening surface treatment lining joining joinability magnesium alloy hardness wear resistance cemented carbide ceramic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Regulation of Vascular Development by CLE Peptide-receptor Systems

引用

Journal of Integrative Plant Biology 2010年第1期52卷 8-16页

作者： Yuki Hirakawa Yuki Kondo Hiroo fukuda Department of Biological Sciences Graduate School of ScienceThe University of Tokyo

Cell division and differentiation of stem cells are controlled by non- cell-autonomous signals in higher organisms. The plant vascular meristem is a stem-cell tissue comprising procambial cells that produce xylem cells on one side and phloem cells on the other side. Recent studies have revealed that TDIF （tracheary element differentiation inhibitory factor）/CLE41/CLE44 peptide signal controls the procambial cell fate in a non-cell-autonomous manner. TDIF produced in and secreted from phloem cells is perceived by TDR/PXY, a leucine-rich repeat receptor kinase located in the plasma membrane of procambial cells. This signal suppresses xylem cell differentiation of procambial cells and promotes their proliferation. In addition to TDIF, some other CLE peptides play roles in vascular development. Here, we summarize recent advances in CLE signaling governing vascular development.

关键词： TDIF Regulation of Vascular Development by CLE Peptide-receptor Systems

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Prediction of Aerodynamic Noise in a Ring Fan Based on Wake Characteristics

引用

Journal of Thermal Science 2011年第2期20卷 144-149页

作者： Soichi Sasaki Masaharu fukuda Masao Tsujino Haruhiro Tsubota Faculty of Engineering Nagasaki University 1-14 Bunkyo-machi Nagasaki 852-8521 Japan Graduate School of Science and Technology Nagasaki University 1-14 Bunkyo-machi Nagasaki 852-8521 Japan Research Division Komatsu Ltd.1200 Manda Hiratsuka-shi Kanagawa 254-8567 Japan

A ring fan is a propeller fan that applies an axial-flow impeller with a ring-shaped shroud on the blade tip side. In this study, the entire flow field of the ring fan is simulated using computational fluid dynamics (CFD); the accuracy of the CFD is verified through a comparison with the aerodynamic characteristics of a propeller fan of current model. Moreover, the aerodynamic noise generated by the fan is predicted on the basis of the wake characteristics. The aerodynamic characteristic of the ring fan based on CFD can represent qualitatively the variation in the measured value. The main flow domain of the ring fan is formed at the tip side of the blade because blade tip vortex is not formed at that location. Therefore, the relative velocity of the ring fan is increased by the circumferential velocity. The sound pressure levels of the ring fan within the frequency band of less than 200 Hz are larger than that of the propeller fan. In the analysis of the wake characteristics, it revealed that Karman vortex shedding occurred in the main flow domain in the frequency domain lower than 200 Hz ; the aerodynamic noise of the ring fan in the vortex shedding frequency enlarges due to increase in the relative velocity and the velocity fluctuation.

关键词： Fan Vortex Aerodynamic Noise Wake Internal Flow

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Vertical impedance functions of pile groups under low-to-high loading amplitudes:numerical simulations and experimental validation

引用

Earthquake Engineering and Engineering Vibration 2023年第3期22卷 647-666页

作者： Usama Zafar Chandra Shekhar Goit Masato Saitoh Riku fukuda School of Science and Engineering Saitama University255 Shimo-OkuboSaitamaJapan

Piles in a group experience additional displacements in soil due to pile-to-pile interactions apart from those resulting from the external *** effect of these interactions determined assuming soil as an elastic and/or viscoelastic material on pile head impedance functions of the pile group is studied by relating the group stiffness to the static stiffness of a single ***,the prevailing elastic solutions may misestimate the resulting pile group response due to the lack of consideration for either soil(material)and/or soil-pile interface *** is well established that soil behaves nonlinearly under moderate-to-high loading amplitudes,and besides,the soil-pile interface nonlinearity can exist even at small loading *** study addresses the effects of these nonlinearities on the vertical impedance functions of a 3×3-pile group using numerical methods by direct analyses and superposition using pile-to-pile interaction *** numerical results are validated using scaled model tests under 1 g *** results highlight the overestimation of pile-to-pile interactions in the pile group when assuming elastic soil *** cases either by direct analyses or superposition approach involving soil and soil-pile interface nonlinearities agree well with the experimental pile group responses under close-to-elastic and nonlinear conditions.

关键词： impedance functions numerical simulations model-scale experiment superposition approach soil-pile interface nonlinearity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Prognostic factors of T4 gastric cancer patients undergoing potentially curative resection

引用

World Journal of Gastroenterology 2011年第9期17卷 1180-1184页

作者： Naoto fukuda Yasuyuki Sugiyama Joji Wada Department of Surgery Teikyo University School of Medicine University Hospital Department of Surgery Kawasaki Kyodo Hospital

AIM:To investigate the prognostic factors of T4 gastric cancer patients without distant metastasis who could undergo potentially curative resection. METHODS:We retrospectively analyzed the clinical data of 71 consecutive patients diagnosed with T4 gastric cancer and who underwent curative gastrectomy at our *** clinicopathological factors that could be associated with overall survival were *** cumulative survival was determined by the Kaplan-Meier method,and univariate comparisons between the groups were performed using the log-rank *** analysis was performed using the Cox proportional hazard model and a step-wise procedure. RESULTS:The study patients comprised 53 men (74.6%)and 18 women(25.4%)aged 39-89 years (mean,68.9 years).Nineteen patients(26.8%)had postoperative morbidity:pancreatic fistula developed in 6 patients(8.5%)and was the most frequent complication,followed by anastomosis stricture in 5 patients (7.0%).During the follow-up period,28 patients(39.4%)died because of gastric cancer recurrence,and 3(4.2%) died because of another disease or *** all patients,the estimated overall survival was 34.1%at 5 *** analyses identified the following statistically significant prognostic factors in T4 gastric cancer patients who underwent potentially curative resection: peritoneal washing cytology(P<0.01),number of metastatic lymph nodes(P<0.05),and venous invasion(P <0.05).In multivariate analyses,only peritoneal washing cytology was identified as an independent prognostic factor(HR=3.62,95%CI=1.37-9.57)for longterm survival. CONCLUSION:Positive peritoneal washing cytology was the only independent poor prognostic factor for T4 gastric cancer patients who could be treated with potentially curative resection.

关键词： Gastric cancer T4 Prognostic factors Peritoneal cytology Venous invasion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

BAYESIAN IMAGE SUPERRESOLUTION AND HIDDEN VARIABLE MODELING

引用

Journal of Systems Science & Complexity 2010年第1期23卷 116-136页

作者： Atsunori KANEMURA Shin-ichi MAEDA Wataru fukuda ShinI SHII Graduate School of Informatics Kyoto University

Superresolution is an image processing technique that estimates an original high-resolutionimage from its low-resolution and degraded *** superresolution tasks,there have beenproblems regarding the computational cost for the estimation of high-dimensional *** are now being overcome by the recent development of fast computers and the developmentof powerful computational techniques such as variational Bayesian *** paper reviewsa Bayesian treatment of the superresolution problem and presents its extensions based on hierarchicalmodeling by employing hidden variables.

关键词： Bayesian estimation hidden variables image superresolution Markov random fields variational estimation.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Recent progress in solution-processed flexible organic photovoltaics

引用

npj Flexible Electronics 2022年第1期6卷 871-884页

作者： Lulu Sun Kenjiro fukuda Takao Someya Thin-Film Device Laboratory RIKEN2-1 HirosawaWakoSaitama 351-0198Japan Center for Emergent Matter Science(CEMS) RIKEN2-1 HirosawaWakoSaitama 351-0198Japan Department of Electrical Engineering and Information Systems School of EngineeringThe University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-8656Japan

The certified power conversion efficiency(PCE)of organic photovoltaics(OPV)fabricated in laboratories has improved dramatically to over 19%owing to the rapid development of narrow-bandgap small-molecule acceptors and wide bandgap polymer donor *** next pivotal question is how to translate small-area laboratory devices into large-scale commercial *** requires the OPV to be solution-processed and flexible to satisfy the requirements of high-throughput and large-scale production such as roll-to-roll *** review summarizes and analyzes recent progress in solution-processed flexible *** a detailed discussion from the perspective of the behavior of the narrow bandgap small-molecule acceptor and wide bandgap polymer donor active layer in solution-processed flexible devices,the existing challenges and future directions are discussed.

关键词： donor narrow translate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Novel System for Xylem Cell Differentiation in Arabidopsis thaliana

引用

Molecular Plant 2015年第4期8卷 612-621页

作者： Yuki Kondo Takashi Fujita Munetaka Sugiyama Hiroo fukuda Department of Biological Sciences Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo-ku tokyo 113-0033 Japan Botanical Gardens Graduate School of Science Tile University of Tokyo 3-7-1 Hakusan Bunkyo-ku Tokyo 112-0001 Japan

During vascular development, procambial and cambial cells give rise to xylem and phloem cells. Because the vascular tissue is deeply embedded, it has been difficult to analyze the processes of vascular development in detail. Here, we establish a novel in vitro experimental system in which vascular development is induced in Arabidopsis thaliana leaf-disk cultures using bikinin, an inhibitor of glycogen synthase kinase 3 proteins. Transcriptome analysis reveals that mesophyll cells in leaf disks synchronously turn into procambial cells and then differentiate into tracheary elements. Leaf-disk cultures from plants expressing the procambial cell markers TDRpro：GUS and TDRpro：YFP can be used for spatiotemporal visualization of procambial cell formation. Further analysis with the tdr mutant and TDIF （tracheary element differentiation inhibitory factor） indicates that the key signaling TDIF-TDR-GSK3s regulates xylem differentiation in leaf-disk cultures. This new culture system can be combined with analysis using the rich material resources for Arabidopsis including cell-marker lines and mutants, thus offering a powerful tool for analyzing xylem cell differentiation.

关键词： Arabidopsis thaliana bikinin leaf-disk culture transcriptome tracheary element differentiation signaling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Development of S-Band High Power Klystron

引用

Chinese Journal of Electronics 2020年第4期29卷 772-778页

作者： WANG Shengchang DONG Dong PEI Shilun ZHOU Zusheng fukuda Shigeki ZHENG Kai Institute of High Energy Physics Chinese Academy of Sciences High Energy Accelerator Research Organization Hubei Hanguang Technology Co. Ltd

A 2998 MHz, 60 MW klystron has been developed for future linear accelerators of synchrotron radiation *** order to save development and construction time, the 2998 MHz, 60 MW klystron is a modified version of an existing 2856 MHz klystron used in linear accelerator of Beijing Electron-Positron Collider Ⅱ.Based on the simulations, it was shown that the scaled version klystron was able to produce more than 60 MW at a 350 kV beam voltage.A prototype was built and *** successfully produced 50 MW output power with an RF pulse width of 4.0μs, which exceeded the operating requirement of China’s High Energy Photon *** also produced 62 MW with an RF pulse width of 1.6μs, which proved the validity of new RF circuit *** paper describes the details of the progresses of this klystron and advantages of this tube development.

关键词： Klystron Linear accelerator Radio-frequency(RF) source

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：