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作者： hirofumi fujii Yuko Kitagawa Kayoko Nakamura Masaki Kitajima Atsushi Kubo Department of Radiology Keio University School of Medicine TokyoJapan Department of Surgery Keio University School of Medicine TokyoJapan Department of Radiology Keio University School of Medicine Tokyo Japan Department of Surgery Keio University School of Medicine TokyoJapan Department of Radiology Keio University School of Medicine TokyoJapan

＜正＞Objectives: We evaluated that feasibility of using Tc-99m tin colloid to identify sentinel nodes （SNs） gastrointestinal malignancies. Methods: The subjects were patients diagnosed with gastrointestinal malignancies considered to be surgically respectable with no clinically obvious nodal metastases. One hundred and sixty-seven patients with gastric cancer, 52 with esophageal cancer, and 61 with colorectal cancer were enrolled in this study. Tc-99m labeled tin colloid （Tc-99m: SnCl2=1:1） was endoscopically injected into the submucosal layer around the tumor. On the following day, patients underwent resection surgery, including resection of regional lymph nodes （LNs）. The radioactivity of resected LNs was measured using a well-type scintillation counter and /or a surgical probe. Any LN with a radioactivity higher than 1/10 of the highest one was defined as a SN. The pathological state of each of the resected LNs was examined using routine H-E staining. Results: The detectability of SNs as well as the sensitivity, false negative （FN） ratio, and diagnostic accuracy of the metastatic status of regional LNs as judged by the pathological results are shown below. Absolute subject numbers （positive cases/total cases examined） are shown in parentheses. Conclusion: Tc-99m tin colloid was able to detect over 90% of the SNs of gastrointestinal malignancies. We suggest that sentinel node concept could be applied to the gastrointestinal tumors as well as breast cancer and malignant melanoma.

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Image Non-Uniformity Correction in 3T Gd-EOB-DTPA-Enhanced Magnetic Resonance Imaging: Comparison among Different Software Versions

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Open Journal of Medical Imaging 2023年第3期13卷 114-126页

作者： hirofumi Hata Yusuke Inoue Keiji Matsunaga Kaoru fujii Toshio Tamiya Ai Nakajima Yuki Takato Kazuki Hashizume Department of Radiology Kitasato University Hospital Sagamihara Japan Department of Diagnostic Radiology Kitasato University School of Medicine Sagamihara Japan School of Medicine Kitasato University Sagamihara Japan

Background: Non-uniformity in signal intensity occurs commonly in magnetic resonance (MR) imaging, which may pose substantial problems when using a 3T scanner. Therefore, image non-uniformity correction is usually applied. Purpose: To compare the correction effects of the phased-array uniformity enhancement (PURE), a calibration-based image non-uniformity correction method, among three different software versions in 3T Gd-EOB-DTPA-enhanced MR imaging. Material and Methods: Hepatobiliary-phase images of a total of 120 patients who underwent Gd-EOB-DTPA-enhanced MR imaging on the same 3T scanner were analyzed retrospectively. Forty patients each were examined using three software versions (DV25, DV25.1, and DV26). The effects of PURE were compared by visual assessment, histogram analysis of liver signal intensity, evaluation of the spatial distribution of correction effects, and evaluation of quantitative indices of liver parenchymal enhancement. Results: The visual assessment indicated the highest uniformity of PURE-corrected images for DV26, followed by DV25 and DV25.1. Histogram analysis of corrected images demonstrated significantly larger variations in liver signal for DV25.1 than for the other two versions. Although PURE caused a relative increase in pixel values for central and lateral regions, such effects were weaker for DV25.1 than for the other two versions. In the evaluation of quantitative indices of liver parenchymal enhancement, the liver-to-muscle ratio (LMR) was significantly higher for the corrected images than for the uncorrected images, but the liver-to-spleen ratio (LSR) showed no significant differences. For corrected images, the LMR was significantly higher for DV25 and DV26 than for DV25.1, but the LSR showed no significant differences among the three versions. Conclusion: There were differences in the effects of PURE among the three software versions in 3T Gd-EOB-DTPA-enhanced MR imaging. Even if the non-uniformity correction method has the sa

关键词： Gd-EOB-DTPA Non-Uniformity Correction 3 Tesla Software Version Image Contrast

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