检索结果-南通市图书馆

维普期刊数据库

Expression levels of K_(ATP)channel subunits and morphological changes in the mouse liver after exposure to radiation

在线全文

学校读者我要写书评

暂无评论

World Journal of Experimental Medicine 2024年第2期14卷 103-113页

作者： Ming Zhou Tao-Sheng Li Hiroshi Abe hideo Akashi Ryoji Suzuki Yoshio Bando Department of Anatomy Akita University Graduate School of MedicineAkita 010-8543Japan Department of Stem Cell Biology Atomic Bomb Disease InstituteNagasaki UniversityNagasaki 852-8523Japan Sendai Old Age Refresh Station A Long-term Care Health FacilitySendai 981-1105Japan

BACKGROUND ATP sensitive K+(K_(ATP))channels are ubiquitously distributed in various of cells and tissues,including the *** play a role in the pathogenesis of myocardial and liver *** To evaluate the radiation-induced changes in the expression of K_(ATP)channel subunits in the mouse liver to understand the potential role of K_(ATP)channels in radiation *** Adult C57BL/6 mice were randomly exposed toγ-rays at 0 Gy(control,n=2),0.2 Gy(n=6),1 Gy(n=6),or 5 Gy(n=6).The livers were removed 3 and 24 h after radiation *** and eosin staining was used for morphological observation;immunohistochemical staining was applied to determine the expression of K_(ATP)channel subunits in the liver *** Compared with the control group,the livers exposed to 0.2 Gyγ-ray showed an initial increase in the expression of Kir6.1 at 3 h,followed by recovery at 24 h after *** to a high dose of 5.0 Gy resulted in decreased expression of Kir6.1 and increased expression of SUR2B at 24 ***,the expression of Kir6.2,SUR1,or SUR2A had no remarkable changes at 3 and 24 h after exposure to any of these *** The expression levels of Kir6.1 and SUR2B in mouse liver changed differently in response to different radiation doses,suggesting a potential role for them in radiation-induced liver injury.

关键词： Radiation exposure ATP-sensitive K^(+)channel Mouse Liver

NiCoZn/C@melamine sponge-derived carbon composites with high-performance electromagnetic wave absorption

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2024年第10期31卷 2274-2286页

作者： Xiubo Xie Heshan Wang hideo Kimura Cui Ni Wei Du Guanglei Wu School of Environmental and Material Engineering Yantai University Shandong Key Laboratory of Eco-Environmental Science for the Yellow River Delta Shandong University of Aeronautics Institute of Materials for Energy and Environment State Key Laboratory of Bio-fibers and Eco-textiles College of Materials Science and Engineering Qingdao University

NiMZn/C@melamine sponge-derived carbon（MSDC） composites（M = Co, Fe, and Mn） were prepared by a vacuum pumping solution method followed by carbonization. A large number of carbon nanotubes（CNTs） homogeneously attached to the surfaces of the three-dimensional cross-linked of the sponge-derived carbon in the NiCoZn/C@MSDC composite, and CNTs were detected in the Ni Fe Zn/C@MSDC and NiMnZn/C@MSDC composites. Ni3ZnC0.7,Ni3Fe, and MnO in-situ formed in the NiFeZn/C@MSDC and Ni Mn Zn/C@MSDC composites. The CNTs in the NiCoZn/C@MSDC composite efficiently modulated its complex permittivity. Thus,the composite exhibited the best performance among the composites, with the minimum reflection loss(RLmin) of-33.1 dB at 18 GHz and thickness of 1.4 mm. The bandwidth for RL of ≤-10 dB was up to 5.04 GHz at the thickness of 1.7 mm and loading of 25wt%. The optimized impedance matching, enhanced interfacial and dipole polarization, remarkable conduction loss, and multiple reflections and scattering of the incident microwaves improved the microwave absorption performance. The effects of Co, Ni, and Fe on the phase and morphology provided an alternative way for developing highly efficient and broadband microwave absorbers.

关键词：

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

利用热机械控制工艺开发优质丝棒材料

上海钢研 2003年第3期 83-87页

作者： hideo hata Ph.D.Hiroshi Yaguchi Masataka Shimoysusa Masao Toyama 秦添艳日本

前言丝棒产品应用十分广泛,如制造汽车和家用电器的部件。它们在制成最终产品前要经过二次或三次加工。随着近年降低成本和全球环保意识的加强。

关键词：热机械控制工艺丝材棒材 TMCP 再结晶颗粒尺寸沉淀相变材料开发

维普期刊数据库

Stratifying the risk of lymph node metastasis in undifferentiated-type early gastric cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第9期21卷 2683-2692页

作者： Yukiko Asakawa Masahiko Ohtaka Shinya Maekawa Mitsuharu Fukasawa Yasuhiro Nakayama Tatsuya Yamaguchi Taisuke Inoue Tomoyoshi Uetake Minoru Sakamoto Tadashi Sato Yoshihiko Kawaguchi Hideki Fujii Kunio Mochizuki Masao Hada Toshio Oyama Tomotaka Yasumura Kosaku Omata Atsushi Nishiyama Keiichi Naito hideo hata Yoshiaki Haba Kazuyuki Miyata Haruhisa Saitoh Yoichi Yamadera Kazuo Miura Akira Kawaoi Tohru Abe Hajime Tsunoda Yuji Honda Masayuki Kurosaki Nobuyuki Enomoto First Department of Internal Medicine Faculty of MedicineUniversity of YamanashiYamanashi 409-3898Japan First Department of Surgery Faculty of MedicineUniversity of YamanashiYamanashi 409-3898Japan Department of Pathology Faculty of MedicineUniversity of YamanashiYamanashi 409-3898Japan Department of Surgery Yamanashi Prefectural Central HospitalYamanashi 400-8506Japan Department of Pathology Yamanashi Prefectural Central HospitalYamanashi 400-8506Japan Department of Surgery Social Insurance Yamanashi HospitalYamanashi 400-0025Japan Department of Pathology Social Insurance Yamanashi HospitalYamanashi 400-0025Japan Department of General Surgery Kofu Kyoritsu HospitalYamanashi 400-0034Japan Department of Pathology Kofu Kyoritsu HospitalYamanashi 400-0034Japan Department of Surgery Kofu Municipal HospitalYamanashi 400-0832Japan Department of Pathology Kofu Municipal HospitalYamanashi 400-0832Japan Department of Surgery Yamanashi Kosei HospitalYamanashi 405-0033Japan Department of Surgery Kanoiwa General HospitalYamanashi 405-0018Japan Department of Pathology Kanoiwa General HospitalYamanashi 405-0018Japan Department of Surgery Social Insurance Kajikazawa HospitalYamanashi 400-0601Japan Department of Surgery Kofu National HospitalYamanashi 400-0006Japan Department of Surgery Fujiyoshida Municipal Medical CenterYamanashi 403-0005Japan Division of Gastroenterology and Hepatology Musashino Red Cross HospitalTokyo 180-0023Japan

AIM:To study how lymph node metastasis(LNM) risk is stratified in undifferentiated-type early gastric cancer(undiff-EGC) dependent on combinations of risk ***:Five hundred and sixty-seven cases with undiff-EGC undergoing gastrectomy with lymphadenectomy were examined *** clinicopathological factors of patient age,location,size,an endoscopic macroscopic tumor form,ulceration,depth,histology,lymphatic involvement(LI) and venous involvement(VI),LNM risk was examined and stratified by conventional statistical analysis and datamining ***:LNM was positive in 44 of 567 cases(7.8%).Univariate analysis revealed > 2 cm,protrusion,submucosal(sm),mixed type,LI and VI as significant prognostic factors and > 2 cm and LI-positive were independent factors by multivariate *** preoperatively evaluable factors excluding LVI,sm and > 2 cm were independent *** to the depth and size,cases were categorized into the low-risk group [m and ≤ 2 cm,0%(LNM incidence)],the moderaterisk group(m and > 2 cm,5.6%; and sm and ≤ 2 cm,6.0%),and the high-risk group(sm and > 2 cm,19.3%).On the other hand,LNM occurred in 1.4% in all LI-negative cases,greatly lower than 28.2% in all LI-positive cases,and LNM incidence was low in LInegative cases even in the moderate- and high-risk ***:LNM-related factors in undiff-EGC were depth and size preoperatively while those were LI and size *** these factors,LI was the most significantly correlated factor.

关键词： Undifferentiated-type early gastric cancer Lymph n

Optimal consumption–investment under partial information in conditionally log-Gaussian models

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Probability, Uncertainty and Quantitative Risk 2023年第1期8卷 95-120页

作者： hideo Nagai MMDS Osaka UniversityToyonaka 560-8531OsakaJapan

Certain Merton type consumption−investment problems under partial information are reduced to the ones of full information and within the framework of a complete market ***,specializing to conditionally log−Gaussian diffusion models,concrete analysis about the optimal values and optimal strategies is performed by using analytical tools like Feynman−Kac formula,or HJB *** explicit solutions to the related forward-backward equations are also given.

关键词： Optimal consumption-investment problem Conditionally log−Gaussian models HJB equations Feynman−Kac formula Forward-backward equations

Crystal structure,chemical bond characteristics,infrared reflection spectrum,and microwave dielectric properties of Nd_(2)(Zr_(1−x)Ti_(x))_(3)(MoO_(4))_(9) ceramics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2023年第1期12卷 82-92页

作者： Jian BAO Yuping ZHANG hideo KIMURA Haitao WU Zhenxing YUE School of Environmental and Material Engineering Yantai UniversityYantai 264005China State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

Microwave dielectric ceramics(MWDCs)with low dielectric constant and low dielectric loss are desired in contemporary society,where the communication frequency is developing to high frequency(sub-6G).Herein,Nd_(2)(Zr_(1−x)Ti_(x))_(3)(MoO_(4))_(9)(NZ_(1−x)T_(x)M,x=0.02-0.10)ceramics were prepared through a solid-phase *** to X-ray diffraction(XRD)patterns,the ceramics could form a pure crystal structure with the R3c(167)space *** internal parameters affecting the properties of the ceramics were calculated and analyzed by employing Clausius-Mossotti relationship,Shannon’s rule,and Phillips-van Vechten-Levine(P-V-L)***,theoretical dielectric loss of the ceramics was measured and analyzed by a Fourier transform infrared(IR)radiation ***,when x=0.08 and sintered at 700℃,optimal microwave dielectric properties of the ceramics were obtained,including a dielectric constant(ε_(r))=10.94,Q·f=82,525 GHz(at 9.62 GHz),and near-zero resonant frequency temperature coefficient(τ_(f))=−12.99 ppm/℃.This study not only obtained an MWDC with excellent properties but also deeply analyzed the effects of Ti^(4+)on the microwave dielectric properties and chemical bond characteristics of Nd_(2)Zr_(3)(MoO_(4))_(9)(NZM),which laid a solid foundation for the development of rare-earth molybdate MWDC system.

关键词： microwave dielectric ceramics(MWDCs) Nd_(2)(Zr_(1−x)Ti_(x))_(3)(MoO_(4))_(9)(NZ_(1−x)T_(x)M) Phillips-van Vechten-Levine(P-V-L)theory theoretical dielectric loss

Statin as a therapeutic agent in gastroenterological cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2022年第1期14卷 110-123页

作者： Norio Uemura Hiromitsu Hayashi hideo Baba Department of Gastroenterological Surgery Graduate School of Medical SciencesKumamoto UniversityKumamoto 860-8556Japan

Statins inhibit 3-hydroxy-3-methylglutaryl-CoA reductase,the rate-limiting enzyme of the mevalonate pathway,and are widely used as an effective and safe approach handle *** mevalonate pathway is a vital metabolic pathway that uses acetyl-CoA to generate isoprenoids and sterols that are crucial to tumor growth and *** studies have indicated that statins improve patient prognosis in various *** research on the mechanisms underlying the antitumor effects of statins is *** development of new anti-cancer drugs is progressing,but increasing medical costs from drug development have become a major *** available,inexpensive and well-tolerated drugs like statins have not yet been successfully repurposed for cancer *** the cancer patients that may benefit from statins is key to improved patient *** review summarizes recent advances in statin research in cancer and suggests important considerations for the clinical use of statins to improve outcomes for cancer patients.

关键词： Statin HMG CoA reductase inhibitor Mevalonate pathway Cancer

Insight into rare-earth-incorporated catalysts:The chance for a more efficient ammonia synthesis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2022年第10期11卷 1499-1529页

作者： Yutong GONG Hongchen LI Can LI Xiaobing BAO hideo HOSONO Junjie WANG State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China School of Materials Science and Engineering Northwestern Polytechnical UniversityXi’an 710072China Materials Research Center for Element Strategy Tokyo Institute of TechnologyYokohama 226-8503Japan

Recent studies have suggested that rare earth(RE)elements in catalysts significantly influence the performance of the ammonia *** REs appear in various forms in the ammonia synthesis catalysts including supports(oxides,hydrides,and nitrides),promotors,and *** the conventional RE oxide-supporting catalysts(mainly Ru/REO),some new RE-containing catalyst systems,such as electrode and nitride systems,could drive the ammonia synthesis via a benign Mars-van Krevelen mechanism or multi-active-site mode,affording high ammonia synthesis performance under mild *** works demonstrate the great potential of RE-containing catalysts for more efficient ammonia *** review summarizes the contributions of different kinds of RE-based catalysts and highlights the function mechanism of incorporated ***,an overview of this area and the challenges for further investigation are provided.

关键词： ammonia synthesis rare earth(RE) heterogeneous catalysis mild conditions mechanism

Structure characteristics and microwave dielectric properties of Pr_(2)(Zr_(1-x)Ti_(x))_(3)(MoO_(4))_(9) solid solution ceramic with a stable temperature coefficient

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2022年第21期116卷 121-129页

作者： Huanrong Tian Jinjie Zheng Lintao Liu Haitao Wu hideo Kimura Yizhong Lu Zhenxing Yue School of Environmental and Material Engineering Yantai UniversityYantai 264005China School of Materials Science and Engineering University of JinanJinan 250022China State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

Pr_(2)(Zr_(1−x)Ti_(x))_(3)(MoO_(4))_(9)(x=0.1-1.0)ceramics were prepared via a conventional solid-state method,the dependence of crystal structure and bond characteristics on microwave dielectric properties was investigated *** X-ray diffraction patterns indicated that the single-phase Pr_(2)Zr_(3)(MoO_(4))_(9)structure was formed in all the *** the Ti^(4+)content increased,the lattice volume gradually decreased,which was ascribed to the fact that the ionic radius of Ti^(4+)was smaller than that of Zr^(4+).Notably,outstanding microwave dielectric properties withεr of 10.73-16.35,Q·f values of 80,696-18,726 GHz and minorτ_(f) values−14.1-−2.6 ppm/℃were achieved in Pr_(2)(Zr_(1−x)Ti_(x))_(3)(MoO_(4))_(9)***ε_(r) increased with the rising x values,which was associated with the increase ofα/Vm *** decreasing Q·f was affected by the decline of lattice energy of[Zr/TiO_(6)]***τf value was dominated by[Zr/TiO_(6)]octahedral distortion,Mo-O bond energy,bond strength and B-site bond ***,infrared reflection spectra suggested that the properties were mainly caused by the absorption of phonon,and the dielectric loss could be further reduced by optimizing the experimental process.

关键词： Pr_(2)(Zr_(1-x)Ti_(x))_(3)(MoO_(4))_(9) Normalized bond length Bond characteristics Raman spectra

维普期刊数据库