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Journal of Chemistry and Chemical Engineering 2012年第4期6卷 363-367页

作者： Takahiro Aoki Yuko Wasada-Tsutsui Tomohiko Inomata Tomohiro Ozawa Yasuhiro Funahashi hideki masuda Department of Frontier Materials Graduate School of Engineering Nagoya Institute of Technology Nagoya 466-8555 Japan Precursory Research for Embryonic Science and Technology （PRESTO） Japan Science and Technology Agency （JST） Saitama 332-0012 Japan

A new ruthenium（II） complex with two different types oftridentate ligands was synthesized, 2,2′：6′,2″-terpyridine （tpy） and 2,6-Bis（（N-benzyl）aminomethyl）pyridine （bbap）： [Ru（tpy）（bbap）]2＋（1）. This compound was designed to form intramolecular π-π stacking interaction between tpy and substituted benzyl groups of bbap. The single-crystal X-ray diffraction analysis revealed that 1 crystallized with orthorhombic space group Aea2 and the ruthenium center has a distorted octahedral coordination geometry with fully chelated tpy and bbap ligands. Simultaneously, in the crystal structure of 1, the central part of ligating tpy was stacked and sandwiched with a pair of capped benzyl substituent groups of bbap, the nearest atomic distance being N...C = 3.28 A.

关键词： Ruthenium(II) complex 2 2′ :6′ 2″-terpyridine aromatic-stacking interaction.

Therapeutic potential of stem cells in subarachnoid hemorrhage

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Neural Regeneration Research 2025年第4期20卷 936-945页

作者： hideki Kanamaru Hidenori Suzuki Department of Neurosurgery Mie University Graduate School of MedicineTsuJapan

Aneurysm rupture can result in subarachnoid hemorrhage,a condition with potentially severe consequences,such as disability and *** the acute stage,early brain injury manifests as intracranial pressure elevation,global cerebral ischemia,acute hydrocephalus,and direct blood–brain contact due to aneurysm *** may subsequently cause delayed cerebral infarction,often with cerebral vasospasm,significantly affecting patient *** complications such as brain volume loss and chronic hydrocephalus can further impact *** the mechanisms of subarachnoid hemorrhage-induced brain injury is paramount for identifying effective *** cell therapy,with its multipotent differentiation capacity and anti-inflammatory effects,has emerged as a promising approach for treating previously deemed incurable *** review focuses on the potential application of stem cells in subarachnoid hemorrhage pathology and explores their role in neurogenesis and as a therapeutic intervention in preclinical and clinical subarachnoid hemorrhage studies.

关键词： delayed cerebral ischemia early brain injury matricellular protein neurogenesis stem cell therapy subarachnoid hemorrhage

On Descriptions of Products of Simplices

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Chinese Annals of Mathematics,Series B 2021年第5期42卷 777-790页

作者： Li YU Mikiya masuda Department of Mathematics Nanjing UniversityNanjing210093China Department of Mathematics Osaka City UniversitySugimotoSumiyoshi-kuOsaka 558-8585Japan

The authors give several new criteria to judge whether a simple convex polytope in a Euclidean space is combinatorially equivalent to a product of simplices. These criteria are mixtures of combinatorial, geometrical and topological conditions that are inspired by the ideas from toric topology. In addition, they give a shorter proof of a well known criterion on this subject.

关键词： Convex polytope Product of simplices Moment-angle complex

Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases

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Cellular & Molecular Immunology 2021年第3期18卷 523-527页

作者： Hiroyuki Yoshitomi hideki Ueno Department of Immunology Graduate School of MedicineKyoto UniversitySakyo-kuf Kyoto 606-8501Japan lnstitute for the Advanced Study of Human Biology Kyoto UniversitySakyo-kuKyoto 606-8501Japan Department of Microbiology Icahn School of Medicine at Mount SinaiNew York 10029 NYUSA Global Health and Emerging Pathogens Institute Icahn School of Medicine at Mount SinaiNew York 10029 NYUSA

The interactions of CD4^(+)T cells and B cells are fundamental for the generation of protective antibody responses,as well as for the development of harmful autoimmune *** studies of human tissues and blood samples have established a new subset of CD4^(+)B helper T cells named peripheral helper T(Tph)*** T follicular helper(Tfh)cells,which interact with B cells within lymphoid organs,Tph cells provide help to B cells within inflamed *** cells share many B helper-associated functions with Tfh cells and induce B cell differentiation toward antibody-producing *** differentiation mechanism is also partly shared between Tph and Tfh cells in humans,and both Tfh and Tph cells can be found within the same tissues,including cancer ***,Tph cells display features distinct from those of Tfh cells,such as the expression of chemokine receptors associated with Tph cell localization within inflamed tissues and a low Bd-6/Blimp1 *** that of Tfh cells,current evidence shows that the target of Tph cells is limited to memory B *** this review,we first summarize recent findings on human Tph cells and discuss how Tph and Tfh cells play shared and distinct roles in human diseases.

关键词： peripheral helper T cells T follicular helper cells CXCL13,Autoantibodies autoimmune diseases

Thermal Conductivity and Tensile Properties of Carbon Nanofiber-Reinforced Aluminum-Matrix Composites Fabricated via Powder Metallurgy: Effects of Ball Milling and Extrusion Conditions on Microstructures and Resultant Composite Properties

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Acta Metallurgica Sinica(English Letters) 2019年第5期32卷 573-584页

作者： Fumio Ogawa Shuji Yamamoto Chitoshi masuda Department of Mechanical Engineering College of Science and Engineering Ritsumeikan University Kanto Gakuin University Kagami Memorial Institute for Materials Science and Technology Waseda University

Carbon nanofiber(CNF)-reinforced aluminum-matrix composites were fabricated via ball milling and spark plasma sintering(SPS), SPS followed by hot extrusion and powder extrusion. Two mixing conditions of CNF and aluminum powder were adopted: milling at 90 rpm and milling at 200 rpm. After milling at 90 rpm, the mixed powder was sintered using SPS at 560 °C. The composite was then extruded at 500 °C at an extrusion ratio of 9. Composites were also fabricated via powder extrusion of powder milled at 200 rpm and 550 °C with an extrusion ratio of 9(R9) or 16(R16). The thermal conductivity and tensile properties of the resultant composites were evaluated. Anisotropic thermal conductivity was observed even in the sintered products. The anisotropy could be controlled via hot extrusion. The thermal conductivity of composites fabricated via powder extrusion was higher than those fabricated using other methods. However, in the case of specimens with a CNF volume fraction of 4.0%, the thermal conductivity of the composite fabricated via SPS and hot extrusion was the highest. The highest thermal conductivity of 4.0% CNF-reinforced composite is attributable to networking and percolation of CNFs. The effect of the fabrication route on the tensile strength and ductility was also investigated. Tensile strengths of the R9 composites were the highest. By contrast, the R16 composites prepared under long heating duration exhibited high ductility at CNF volume fractions of 2.0% and 5.0%. The microstructures of composites and fracture surfaces were observed in detail, and fracture process was elucidated. The results revealed that controlling the heating and plastic deformation during extrusion will yield strong and ductile composites.

关键词： Al composite Carbon nanofiber Ball milling Hot extrusion Microstructure and performance

Complex trace element effects of source mixing-fractional crystallization composite processes in Kalaan granodiorite pluton along Wulungu tectonic belt,northern Xinjiang

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Science China Chemistry 1995年第8期38卷 987-995页

作者：刘伟 A.masuda Changsha Institute of Geotectonics Chinese Academy of SciencesChangsha 410013China Chemistry Department Faculty of ScienceThe University of TokyoJapan

Mixing-fractional crystallization composite processes generate 6 complex patterns,which are synthesized into 3 models,on C^2_1/C^3_1-C^1_1/C^3_1 ratio correlation plots of trace eleroents E_1,E_2,E_3 according to their relative *** of the six effects are clearly displayed on ratio-ratio correlation plots of trace elements in the Kalaan granodiorite pluton,indicative of a source mixing-fractional crystallization composite *** overlying lithospheric mantle was modified by the subduction of oceanic plate during Palaeozoic. The incompatibility order of the 7 concerned trace elements is D_(Ta)

关键词： trace element effects geochemical behavior source mixing-fractional crystallization granodiorite Kalaan

A construction method of matroidal networks

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Science China(Information Sciences) 2012年第11期55卷 2445-2453页

作者： IMAI hideki Faculty of Science and Engineering Chuo University Tokyo 112-8551Japan

This paper discusses the question whether a network-matroid construction can be modified so that all matroid dependencies are re?ected in the *** propose a novel construction method for a matroidal network to address this ***,we investigate some properties of the matroidal network based on our construction *** relations between the matroidal network and its associated matroid are developed through various examples.

关键词： capacity matroid matroidal network network coding

Hunting hidden pieces of signaling pathways in hepatocellular carcinoma

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Hepatobiliary Surgery and Nutrition 2019年第1期8卷 74-76页

作者： Mari masuda Laboratory of Collaborative Research Division of Cellular SignalingNational Cancer Center Research InstituteTokyoJapan

Advanced hepatocellular carcinoma(HCC)has a poor prognosis with limited treatment *** the last decade,sorafenib,a multi-tyrosine kinase inhibitor(TKI),has been the only available systemic agent for first-line treatment of unresectable HCC(1).Recently,another multi-TKI,lenvatinib,was added to the list of first-line treatment alternatives based on the results of the phase III RREFLECT *** second-line treatment,two multi-TKIs,regorafenib and cabozantinib,were approved in 2016 and 2018,*** other targeted therapies,ramucirumab and an anti-PD-1 antibody,nivolumab,will soon be added in a second-line setting to the therapeutic *** agents,however,generally lead to disease stabilization rather than tumor *** of complete remission with available systemic treatments still remains rare,however,and therapeutic breakthroughs are still needed.

关键词： hepatocellular prognosis treatment

Torsion in the Cohomology of Torus Orbifolds

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Chinese Annals of Mathematics,Series B 2017年第6期38卷 1247-1268页

作者： Hideya KUWATA Mikiya masuda Haozhi ZENG Department of Mathematics Osaka City UniversitySumiyoshi-kuOsaka 558-8585Japan School ofMathematical Sciences Fudan UniversityShanghai 200433China.

The authors study torsion in the integral cohomology of a certain family of2 n-dimensional orbifolds X with actions of the n-dimensional compact torus. Compact simplicial toric varieties are in our family. For a prime number p, the authors find a necessary condition for the integral cohomology of X to have no p-torsion. Then it is proved that the necessary condition is sufficient in some cases. The authors also give an example of X which shows that the necessary condition is not sufficient in general.

关键词： Toric orbifold Cohomology Torsion

Estimating reflectance and shape of objects from a single cartoon-shaded image

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Computational Visual Media 2017年第1期3卷 21-31页

作者： hideki Todo Yasushi Yamaguchi Tokyo University of Technology The University of Tokyo

Although many photorealistic relighting methods provide a way to change the illumination of objects in a digital photograph, it is currently difficult to relight digital illustrations having a cartoon shading style. The main difference between photorealistic and cartoon shading styles is that cartoon shading is characterized by soft color quantization and nonlinear color variations that cause noticeable reconstruction errors under a physical reflectance assumption, such as Lambertian reflection. To handle this non-photorealistic shading property, we focus on shading analysis of the most fundamental cartoon shading technique. Based on the color map shading representation, we propose a simple method to determine the input shading as that of a smooth shape with a nonlinear reflectance property. We have conducted simple ground-truth evaluations to compare our results to those obtained by other approaches.

关键词： non-photorealistic rendering cartoon shading relighting quantization