检索结果-南通市图书馆

Autonomic Dysreflexia Severity between Urodynamics and Cystoscopy in Patients with Spinal Cord Injury above T6

International Journal of Clinical Medicine 2021年第8期12卷 351-356页

作者： heyi zhen Tianhai Huang Xiaoyi Yang Qiuling Liu Qingqing Li Maping Huang Hui Chen Department of Traumatic Brain Injury Rehabilitation Guangdong Province Work Injury Rehabilitation Hospital Guangzhou China Department of Urology Guangdong Provincial Work Injury Rehabilitation Hospital Guangzhou China

Objective: The objective is to evaluate autonomic dysreflexia (AD) severity between urodynamics and cystoscopy in patients with spinal cord injury (SCI) above thoracic 6 (T6). Design: It is a cross-sectional survey. Subject and methods: The study was carried out in 22 patients with SCI above T6 who underwent both procedures of urodynamics and cystoscopy;all patients developed episodes of AD. The systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured and recorded at the beginning and during the various stages of the two examinations. AD was defined as a rise in SBP above 20 mm Hg. Results: There was no significant difference in SBP and DBP at baseline before urodynamics and cystoscopy. Both urodynamics and cystoscopy triggered episodes of AD. The volume of water instilled during cystoscopy was typically standard and smaller (150 mL) in comparison with urodynamics, where volume varied depending on cystometric bladder capacity (the mean bladder volume in our study was 234.86 ± 139.06 mL). The SBP was significantly different between cystoscopy and urodynamics (49.23 ± 23.07 mm Hg and 35.14 ± 15.75 mm Hg, respectively;P = 0.023). Conclusions: Although bladder distension during cystoscopy was less than that in urodynamics, the severity of AD was more pronounced during cystoscopy. It is recommended that monitoring of cardiovascular parameters during these procedures should be routinely performed.

关键词： Autonomic Dysreflexi Spinal Cord Injury Urodynamics Cystoscopy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Combined Detrusor and External Urethral Sphincter BTX-A Injections for Detrusor Overactivity and Detrusor External Sphincter Dyssynergia Secondary to Spinal Cord Injury

引用

Open Journal of Urology 2021年第2期11卷 45-51页

作者： Maping Huang heyi zhen Tianhai Huang Xiaoyi Yang Qiuling Liu Qingqing Li Hui Chen Department of Urology Guangdong Provincial Work Injury Rehabilitation Hospital Guangzhou China Department of Traumatic Brain Injury Rehabilitation Guangdong Province Work Injury Rehabilitation Hospital Guangzhou China

Objective: To evaluate the efficacy and safety of Combined detrusor and external urethral sphincter BTX-A injections for detrusor overactivity (DO) and detrusor external sphincter dyssynergia (DESD) secondary to spinal cord injury. Study Design: Prospective study. Methods: The study was carried out in 18 SCI patients with detrusor overactivity (DO) and detrusor external sphincter dyssynergia (DESD) receiving Combined detrusor and external urethral sphincter BTX-A injections treatment. Contain 200 U botulinum toxin intradetrusor and 100 U external urethral sphincter injections. The effective outcomes included maximum detrusor pressure at first DO and DESD (PdetmaxDO-DESD), volume at first DO and DESD (VDO-DESD), maximum urethral closure pressure (MUCP), and Incontinence-Specific Quality-of-Life Instrument (I-QoL). Adverse events were recorded. Results: All patients experienced a significant mean reduction in PdetmaxDO-DESD (50.75%), maximum urethral closure pressure (26.34%) and a significant mean increase in VDO-DESD (63.00%) 12-weeks post-injection. Significant (p Conclusion: Combined detrusor and external urethral sphincter BTX-A injections is a good choice for patients with DO and DESD secondary to spinal cord injury. It could not only protect the upper urinary tract but also improve quality of life.

关键词： Detrusor Overactivity Detrusor External Sphincter Dyssynergia BTX-A Spinal Cord Injury

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Initial Experience with Mirabegron for the Treatment of Neurogenic Lower Urinary Tract Dysfunction

引用

Open Journal of Urology 2021年第8期11卷 305-311页

Background: Though anticholinergic drugs are considered the standard treatment for neurogenic detrusor overactivity, it is far from an ideal tool, because of their adverse effects such as Constipation or not respond sufficiently for a substantial proportion of patients. Recently mirabegron has become a commonly used overactive bladder medication in the general population, but few studies about mirabegron for the treatment of neurogenic detrusor overactivity. Objective: To evaluate the efficacy and safety of mirabegron for the treatment of neurogenic lower urinary tract dysfunction. Study Design: Prospective study. Methods: This prospective study included 13 adult patients with neurogenic lower urinary tract dysfunction as a result of spinal cord injury. All patients receiving mirabegron treatment (50 mg once daily) at least 6 weeks. The effective outcomes included the mean urine volume per catheterization, urinary incontinence episodes and Incontinence Specific Quality of Life Instrument. We monitored the blood pressure and heart rate to assess the cardiovascular safety, other adverse events were also recorded. Results: A total of 13 patients were included. After 6 weeks of treatment, all patients experienced a significant increase in the mean volume of per catheterization from 238.46 ± 65.43 ml to 327.69 ± 59.04 ml (p = 0.001). There is a significant reduction in the volume of urine leakage (463.85 ± 247.98 ml VS 180.00 ± 190.96 ml, p = 0.003) and incontinence episodes per 24 h (4.46 ± 2.03 VS 1.92 ± 1.50, p = 0.001). Significant improvement in mean Incontinence Specific Quality of Life Instrument was also found (p = 0.001). No patients reported dry mouth during the study, and the cardiovascular safety were acceptable. Conclusion: Mirabegron is safe and effective in the treatment of neurogenic lower urinary tract dysfunction. It might be a good choice for reducing

关键词： Neurogenic Lower Urinary Tract Mirabegron Detrusor Overactivity Spinal Cord Injury

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

膀胱内注射A型肉毒毒素治疗脊髓损伤伴自主神经反射亢进的疗效

引用

国际医药卫生导报 2021年第14期27卷 2088-2091页

作者：郑荷依黄马平黄天海杨晓毅刘秋玲李青青陈晖广东省工伤康复医院颅脑损伤康复科广州510440 广东省工伤康复医院泌尿外科广州510440

目的评价膀胱内注射A型肉毒毒素治疗脊髓损伤伴自主神经反射亢进(AD)的疗效。方法选取2018年6月至2019年12月本院接受膀胱内注射A型肉毒毒素治疗逼尿肌过度活动的15例T6及以上脊髓损伤患者,男11例,女4例,年龄(38.6±11.9)岁。AD是指患... 详细信息

目的评价膀胱内注射A型肉毒毒素治疗脊髓损伤伴自主神经反射亢进(AD)的疗效。方法选取2018年6月至2019年12月本院接受膀胱内注射A型肉毒毒素治疗逼尿肌过度活动的15例T6及以上脊髓损伤患者,男11例,女4例,年龄(38.6±11.9)岁。AD是指患者收缩压升高超过20 mmHg(1 mmHg=0.133 kPa)。治疗前和治疗后1个月对尿动力参数和AD进行比较分析。尿动力学主要参数包括最大逼尿肌压力、膀胱容量。在尿动力学期间记录心血管参数,如收缩压,以揭示AD的存在及其严重程度(即收缩压较基线的变化)。此外,进行尿失禁生活质量量表(I-QOL)评分。结果膀胱注射A型肉毒毒素治疗后患者最大逼尿肌压力为(32.00±9.464)cmH2O(1 cmH_(2)O=0.098 kPa),低于治疗前(50.00±16.737)cmH_(2)O,膀胱容量为(317.33±41.095)ml,高于治疗前(178.40±64.357)ml,差异均有统计学意义(均P<0.05);治疗前后患者尿动力检查进行膀胱灌注之前测得患者的血压差异无统计学意义(P=0.561);治疗后患者尿动力检查期间最大灌注量收缩压和收缩压较基线变化值分别为(131.73±6.497)mmHg、(31.07±7.851)mmHg,均低于治疗前(151.53±11.025)mmHg、(48.73±10.633)mmHg,差异均有统计学意义(均P<0.05)。治疗后每次导尿量和I-QOL评分分别为(343.33±37.161)ml、(77.60±2.694)分,均高于治疗前(196.67±44.186)ml、(48.60±1.642)分,差异均有统计学意义(均P<0.05)。结论膀胱内注射A型肉毒毒素不仅能降低膀胱压力,保护上尿路,而且是治疗脊髓损伤患者AD较好的选择,减少AD对机体的影响。

关键词：自主神经反射亢进 A型肉毒毒素脊髓损伤逼尿肌过度活动

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

ICU严重免疫失衡疾病——持续炎症-免疫抑制-分解代谢综合征

引用

中华危重病急救医学 2017年第8期29卷 760-764页

作者：苏和毅莫泽珣陈珍郭振辉广州军区广州总医院老年重症医学科广东广州510010 广东省老年感染与器官功能支持重点实验室广州市老年感染与脏器功能支持重点实验室

持续炎症-免疫抑制-分解代谢综合征（PICS）在多器官功能衰竭（MOF）的概念上进一步拓展,反映出机体促炎反应对抗炎反应的优势逐渐被逆转,形成了持续低水平的炎症状态和严重的免疫抑制状态.虽然重症抢救管理技术的发展使危重患者的早期... 详细信息

持续炎症-免疫抑制-分解代谢综合征（PICS）在多器官功能衰竭（MOF）的概念上进一步拓展,反映出机体促炎反应对抗炎反应的优势逐渐被逆转,形成了持续低水平的炎症状态和严重的免疫抑制状态.虽然重症抢救管理技术的发展使危重患者的早期存活率显著提高,但大部分患者的晚期预后仍不容乐观.PICS防治困难、晚期病死率高,且发病率逐年上升,是重症加强治疗病房（ICU）面临的重要挑战.通过梳理对PICS的认识、总结PICS各免疫环节的特征性变化,探索具备PICS早期识别和免疫状态判断潜力的指标,为PICS防治提供新的思路.

关键词：炎症,持续性免疫抑制分解代谢免疫失衡

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pretreatment with probiotics Enterococcus faecium NCIMB 11181 attenuated Salmonella Typhimurium-induced gut injury through modulating intestinal microbiome and immune responses with barrier function in broiler chickens

引用

Journal of Animal Science and Biotechnology 2023年第2期14卷 666-689页

作者： Yujing Shao Wenrui zhen Fangshen Guo Zeqiong Hu Kaichen Zhang Linhua Kong Yuming Guo Zhong Wang College of Biology China Agricultural UniversityBeijingChina State Key Laboratory of Animal Nutrition College of Animal Science and TechnologyChina Agricultural UniversityBeijingChina College of Animal Science and Technology Henan University of Science and TechnologyProvince of HenanLuoyangChina Tengzhou heyi Food Co.Ltd ZaozhuangShandong ProvinceChina.

Background:Preventing Salmonella infection and colonization in young birds is key to improving poultry gut health and reducing Salmonella contamination of poultry products and decreasing salmonellosis for human consumption(poultry meat and eggs).Probiotics can improve poultry *** present study was conducted to investigate the impact of a probiotics,Enterococcus faecium NCIMB 11181(*** NCIMB 11181)on the intestinal mucosal immune responses,microbiome and barrier function in the presence or absence of Salmonella Typhimurium(***-imurium,ST)***:Two hundred and forty 1-day-old Salmonella-free male broiler chickens(Arbor Acres AA+)were randomly allocated to four groups with 6 replicate cages of 10 birds *** four experimental groups were follows:(1)nega-tive control(NC),(2)***,challenged positive control(PC),(3)the *** NCIMB 11181-treated group(EF),(4)the *** NCIMB 11181-treated and ***-challenged group(PEF).Results:Results indicated that,although continuous feeding *** NCIMB 11181 did not obviously alleviate growth depression caused by *** challenge(P>0.05),*** NCIMB 11181 addition significantly blocked Salmonella intestinal colonization and translocation(P<0.05).Moreover,supplemental *** NCIMB 11181 to the infected chickens remarkably attenuated gut morphological structure damage and intestinal cell apoptosis induced by *** infection,as evidenced by increasing gut villous height and reducing intes-tinal TUNEL-positive cell numbers(P<0.05).Also,*** NCIMB 11181 administration notably promoting the production of anti-Salmonella antibodies in intestinal mucosa and serum of the infected birds(P<0.05).Addition-ally,16S rRNA sequencing analysis revealed that *** NCIMB 11181 supplementation ameliorated ***-rium infection-induced gut microbial dysbiosis by enriching Lachnospiracease and Alistipes levels,and suppressing Barnesiella *** function

关键词： Broiler chickens Enterococcus faecium Gut health Salmonella Typhimurium

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dietary coated essential oil and organic acid mixture supplementation improves health of broilers infected with avian pathogenic Escherichia coli

引用

Animal Nutrition 2023年第1期12卷 245-262页

作者： Van Hieu Pham Waseem Abbas Jinyu Huang Fangshen Guo Kaichen Zhang Linhua Kong Wenrui zhen Yuming Guo Zhong Wang State Key Laboratory of Animal Nutrition College of Animal Science and TechnologyChina Agricultural UniversityBeijing100193China Faculty of Animal Science and Veterinary Medicine Thai Nguyen University Agriculture and ForestryThai NguyenViet Nam Menon Animal Nutrition Technology Co.Ltd. Shanghai201807China Tengzhou heyi Food Co.Ltd. Zaozhuang277000China

Colibacillosis caused by avian pathogenic Escherichia coli(APEC)is a very prevalent disease in poultry farms in *** exploration of effective non-antibiotic substances is of great significance for the control of APEC *** experiment evaluated the efficacy of coated essential oil and organic acid(EOA)supplementation to prevent *** O78 infection in broiler chickens.A total of 288 one-day-old male broiler chicks were randomly distributed into 4 groups with 6 replicates per *** were fed a diet either supplemented with EOA(500 mg/kg feed)or not,and either uninfected or infected with *** O78 *** showed that *** O78 infection reduced body weight gain,increased mortality and the ratio of feed to gain along with cecal and liver *** load,damaged gut mucosa,induced local and systemic inflammation,and altered cecal microbial composition,diversity and function(P<0.05).Supplemental EOA improved feed conversion efficiency,lowered gross lesion scores and cecal *** population,enhanced intestinal goblet cells and serum IgG concentration,and tended to decrease serum IL-12 production(P<0.05).Essential oil and organic acid addition downregulated IFN-γmRNA,tended to decrease mucin-2 mRNA levels while upregulating IL-10 mRNA,and tended to increase ZO-1 gene expression in the jejuna of infected birds at 7 d after *** O78 challenge(P<0.05).The 16S rRNA gene sequencing indicated that both EOA addition and *** O78 challenge altered the diversity and composition of the cecal microbiota ***,infected birds fed EOA showed decreased Bacteroidetes and genus Lactobacillus abundance compared with the infected *** analysis showed that Firmicutes,Ruminococcaceae,Clostridiales,Clostridia,Lactobacillus,Lactobacilaceae,and cc-115 were enriched in the non-infected but EOA-treated group(P<0.05).Collectively,dietary EOA supplementation could mildly alleviate ***-induced gut injury and inflammation.

关键词： Encapsulated essential oil and organic acid mixture Avian pathogenic Escherichia coli Health Broiler chicken

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

计算机组装与维护实训工具盘的研制

引用

实验技术与管理 2020年第1期37卷 230-234页

作者：胡振谭鹤毅张晓琪周金容代霜春南充职业技术学院电子信息工程系四川南充637131

针对"计算机组装与维护"课程实训中软件的使用和管理问题,设计、制作了一种计算机系统安装维护工具盘。根据课程的教学内容和技能培养目标,按照计算机安装、维护工作要求设计其功能模块和目录结构,将所需软件全部集成于一个工具盘中,并... 详细信息

针对"计算机组装与维护"课程实训中软件的使用和管理问题,设计、制作了一种计算机系统安装维护工具盘。根据课程的教学内容和技能培养目标,按照计算机安装、维护工作要求设计其功能模块和目录结构,将所需软件全部集成于一个工具盘中,并通过直观、易用的选单系统实现各项功能调用。实训教学的实践说明该工具盘完全能够满足课程实训和实际应用要求。

关键词：计算机组装与维护工具盘实训教学

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

柱后衍生阳离子交换色谱法测定缤菲美肤养润抑菌凝胶中氨基酸的含量

引用

香料香精化妆品 2020年第1期 37-40页

作者：成臻成和颐成源西安北方光电科技防务有限公司检测计量中心陕西西安710043 西安高新第一中学陕西西安710075 西安祝康康健康管理咨询有限公司陕西西安710003

采用阳离子交换色谱柱分离氨基酸,通过柱后衍生化检测分析,梯度洗脱,其中溶液泵(A泵)流速为0.50 mL/min,茚三酮泵(M泵)流速为0.25 mL/min,检测波长为440 nm(脯氨酸)和570 nm(其余氨基酸),进样量为50μL,建立了缤菲美肤养润抑菌凝胶中氨... 详细信息

采用阳离子交换色谱柱分离氨基酸,通过柱后衍生化检测分析,梯度洗脱,其中溶液泵(A泵)流速为0.50 mL/min,茚三酮泵(M泵)流速为0.25 mL/min,检测波长为440 nm(脯氨酸)和570 nm(其余氨基酸),进样量为50μL,建立了缤菲美肤养润抑菌凝胶中氨基酸的含量测定方法。结果表明,各氨基酸检测的线性关系良好;精密度(相对标准偏差,RSD)范围0.77%~1.30%,重复性(RSD)范围0.87%~1.96%;平均回收率范围95.81%~102.45%。所建立的分析方法准确,具有良好的重复性和回收率,可作为氨基酸的定量分析方法。

关键词：柱后衍生阳离子交换色谱法缤菲美肤养润抑菌凝胶氨基酸

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

高效阴离子交换色谱–脉冲安培法测定生态养护抑菌凝胶中的褐藻寡糖

引用

化学分析计量 2019年第6期28卷 43-47页

作者：成臻成和颐成源西安北方光电科技防务有限公司检测计量中心西安710043 西安高新第一中学西安710075 西安祝康康健康管理咨询有限公司西安710003

建立高效阴离子交换色谱-脉冲安培检测法测定生态养护抑菌凝胶中褐藻寡糖含量的方法。采用阴离子交换柱CarboPac PA10(250 mm×2 mm,3.5μm),以氢氧化钠、乙酸钠和水为洗脱液进行梯度洗脱,柱温为35℃,流量为0.8 mL/min。α-L-古罗糖醛... 详细信息

建立高效阴离子交换色谱-脉冲安培检测法测定生态养护抑菌凝胶中褐藻寡糖含量的方法。采用阴离子交换柱CarboPac PA10(250 mm×2 mm,3.5μm),以氢氧化钠、乙酸钠和水为洗脱液进行梯度洗脱,柱温为35℃,流量为0.8 mL/min。α-L-古罗糖醛酸单糖(PG)和β-D-甘露糖醛酸单糖(PM)的质量浓度分别在0.25~9.0μg/mL和0.18~8.4μg/mL范围内与色谱峰面积线性关系良好,线性相关系数分别为0.9997和0.9998,检出限分别为0.06,0.03μg/mL,定量限分别为0.20,0.10μg/mL。测定结果的相对标准偏差分别为1.11%,1.25%(n=6),加标回收率分别为101.03%和95.22%。该方法简便易行,灵敏度高,重现性好,适用于生态养护抑菌凝胶中褐藻寡糖的分析。

关键词：褐藻寡糖 α-L-古罗糖醛酸单糖 β-D-甘露糖醛酸单糖生态养护抑菌凝胶高效阴离子交换色谱-脉冲安培检测法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：