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作者： henrique munhoz de almeida pinto street 上海交通大学

学位级别：硕士

In 2013,the president of the People's Republic of China announced that the Chinese government intended to create the most ambitious regional economic cooperation initiative of the 21 st century,the Belt and Road *** Belt and Road initiative is an initiative that aims to improve regional integration,increase trade and stimulate economic growth by way of mega infrastructure *** initiative is subdivided into two main components,with the Silk Road Economic Belt representing the initiative's land component,and the 21 st Century Maritime Silk Road representing the sea *** Silk Road Economic Belt focuses on improving regional cooperation through better connectivity among countries located along the ancient Silk *** countries belonging to the Silk Road Economic Belt initiative are the main focus of this *** first purpose of this thesis is to investigate the relationship between transportation infrastructure,more specifically railway and roadway infrastructure,and economic growth in Silk Road Economic Belt *** second purpose of this thesis is to evaluate the economic impact of participating in the *** research employs panel data analysis which includes 57 countries,36 of which belong to the Silk Road Economic Belt initiative,using the annual data from the period 2007 to *** regression model was formed by taking GDP per capita growth as the dependent variable,roadway infrastructure and railway infrastructure as explanatory variables,and a set of control variables was added to complement the *** fixed effects model was used to obtain the results,supported by the Hausman test and poolability *** findings reveal that there is a negative relationship between roadway infrastructure and economic growth,while railway infrastructure was statistically *** negative relationship between roadway infrastructure and economic growth diminishes once countries participate in the Silk Road Economic

关键词： Transport Infrastructure Economic Growth Granger

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Microstructure and mechanical behavior of similar butt-joints of ZK60 and ZK60-1.5RE magnesium alloys produced by linear friction stir welding

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Journal of Magnesium and Alloys 2021年第5期9卷 1802-1817页

作者： Erenilton Pereira da Silva Ricardo henrique Buzolin Ulises Alfaro Guillermo Requena Haroldo Calvalcanti pinto Institute of Engineering Science and Technology(IECT)Federal University of Vales do Jequitinhonha e Mucuri(UFVJM)JanaúbaMGBrazil department of Materials Engineering São Carlos School of Engineering(EESC)University of São Paulo(USP)São Carlos-SP CEP 13563-120Brazil Christian Doppler Laboratory for design of High-Performance Alloys by Thermomechanical Processing Kopernikusgasse 24Graz 8010Austria Institute of Materials Science Joining and Forming at Graz University of Technology opernikusgasse 24/IGraz 8010Austria German Aerospace Center(DLR)Institute of Materials Research Linder HöheCologne 51147Germany RWTH Aachen University Metallic Structures and Materials Systems for Aerospace EngineeringD-52062 AachenGermany.

The microstructure and mechanical properties of butt-joints produced by linear friction stir welding of similar plates of as-cast ZK60 and modified ZK60 with 1.5 wt.%RE(ZK60-1.5 RE)are *** thermomechanical affected zone is investigated in both advancing and retrieving sides,and the microstructure is compared to the base metal and the stirred *** backscattered diffraction measurements provide the average microstructural features of the transformed *** mechanical properties are assessed using hardness,tensile testing,and surface residual stress measured using X-ray *** torque and heat input are obtained for the ZK60-1.5 RE compared to the *** thermomechanical affected zone is notably larger for the ZK60 compared to the ZK60-1.5 RE.A gradient microstructure is formed in thermomechanical affected zones where deformed grains are progressively more recrystallised towards the stirred *** is no visible interface between the thermomechanical affected zone and the stirred zone.A fine and partially recrystallised microstructure is formed in the stirred *** retrieving side of the ZK60-1.5 RE has a slightly more refined microstructure compared to the other investigated *** measured with increment in the maximum intensity of the(0001)increases towards to stirred *** formed microstructure is correlated with the role of twinning,recovery,static,and dynamic recrystallisation that can occur during friction stir *** and grains with large misorientation spread are more pronounced in the thermomechanical affected zone and regions towards the base *** low angle grain boundaries are observed towards the stirred *** refined recrystallised grains decorating the grain in the thermomechanical affected zone,a mosaic-like of low and high angle grain boundaries are observed in the stirred *** joints have comparable surface residual *** friction stir welding improved th

关键词： ZK60 Mischmetal FSW Recrystallization Microstructure Thermomechanical

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Areas with evidence of equity and their progress on mortality from tuberculosis in an endemic municipality of southeast Brazil

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Infectious Diseases of Poverty 2017年第1期6卷 1185-1195页

作者： Mellina YAMAMURA Marcelino SANTOS NETO Francisco CHIARAVALLOTI NETO Luiz henrique ARROYO Antonio Carlos Vieira RAMOS Ana Angelica Rego de QUEIROZ Aylana de Souza BELCHIOR Danielle Talita dos SANTOS Juliane de almeida CRISPIM Ione Carvalho pinto Severina Alice da Costa UCHOA Regina Celia FIORATI Ricardo Alexandre ARCENCIO School of Nursing of the University of Sao Paulo Ribeirao Preto Campus(EERP/USP)Ribeirao retoSPBrazil Federal University of Maranhao(UFMA) Sao LuísMABrazil School of Public Health of the University of Sao Paulo(FSP/USP) Sao PauloSPBrazil Federal University of Rio Grande do Norte(UFRN) NatalRNBrazil School of Medicine of the University of Sao Paulo Ribeirao Preto Campus(FMRP/USP)Ribeirao PretoSPBrazil

Background:In Brazil,people still fall ill and die from tuberculosis(TB),and this can be explained by the significant impasse in the equity of distribution of therapeutic resources to the population as a *** aim was to identify geographical areas which have shown progress in terms of equity(of income,schooling and urban occupancy)and test its effect on mortality from TB in a municipality of southeast ***:It is an ecological study considering TB as the basic cause for deaths registered between 2006 and 2013 on the Mortality Information System and other variables obtained through the demographic Census of the Brazilian Institute of Geography and Statistics(2010).The geographical area for analysis comprised the areas of coverage of the health *** indicators have been constructed through the Principal Component Analysis(PCA).The cases were geocoded and the annual mortality rate from TB was calculated with smoothing using the local empirical Bayesian *** linear regression was then *** was confirmation of the existence of spatial dependence of residue through the application of the Global Moran I test,and application of the Models with Global Spatial Effects,to identify the best standard of spatial ***:The mortality rates ranged from 0.00 to 2.8 deaths per 100,000 people,per *** the PCA,three indicators were constructed,and designated as indicators of income,social inequality,and social *** multiple linear regression,the indicator of social equity was statistically significant(Pdependence(Moran I=0.21,P=0.003455).The best model to deal with existing spatial dependence was the Spatial Lag ***:The better social conditions have shown progress in reducing mortality from TB,thereby reinforcing the achievement of Sustainable development *** addition,cartography was also applied,which can be replicated

关键词： Tuberculosis Spatial analysis Mortality Cause of death

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Biochar influences the cane fields’microbiota and the development of pre-sprouted sugarcane seedlings

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Waste Disposal and Sustainable Energy 2023年第1期5卷 75-88页

作者： Bruna Cristina pinto Adriana Barboza Alves Osania Emerenciano Ferreira Gustavo henrique Gravatim Costa Magno Andréde Oliveira Augusto Cesar da Silva Bezerra Alan Rodrigues Teixeira Machado Postgraduate Program in Environmental Sciences State University of Minas GeraisFrutal UnityFrutalMinas Gerais38202-436Brazil department of Agricultural and Biological Sciences State University of Minas GeraisFrutal UnityFrutalMinas Gerais38208-436Brazil Postgraduate Program in Geotechnical Engineering Federal University of Ouro PretoOuro PretoMinas Gerais35400-000Brazil department of Transport Engineering Federal Center for Technological Education of Minas GeraisBelo HorizonteMinas Gerais30421-169Brazil department of Exact Sciences State University of Minas GeraisJoão Monlevade UnityJoão MonlevadeMinas Gerais35930-314Brazil

This research investigates the soil conditioning effect of sugar cane fields with biochar produced from sugarcane *** influence on the physicochemical and microbiological conditions of the soil and the agronomic performance of sugarcane seedlings was *** this end,the biochar from sugarcane bagasse was produced by pyrolysis in a double drum oven and mixed with soil at rates of 0,1%,3%,and 5%(in weight).The experiment was installed in a greenhouse with two evaluation periods(30 days and 60 days)and five *** pot received a pre-sprouted cane seedling,and the analysis of colony-forming units(bacteria and fungi),physicochemical characteristics of the soil,and growth and development of sugarcane were performed per *** biochar showed a high fixed carbon content(72%)and a specific surface area estimated by the adsorption of methylene blue of 50 m2 g−***,its structure is porous and contains important nutrients(e.g.,CaO,K2O,and P2O5).In the periods evaluated,the applications of the 3%and 5%(in weight)rates of biochar reduced most of the soil fertility ***,the chemical analyses indicated that the sugarcane field soil collected already possessed high *** microbiota was influenced,but only the application of the 3%(in weight)rate at 60 days after planting showed a significant positive effect on the number of bacteria forming units,with an increase of approximately 385%.On the other hand,no significant positive effect on sugarcane development was ***,biochar application in high-fertility sugarcane plantation soil did not result in gains for sugarcane development in the periods evaluated.

关键词： Soil Biometry Microbiology Double drum oven Biochar

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Photodynamic Therapy with Phthalomethyl D: Perspectives against SARS-CoV-2

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Journal of Biosciences and Medicines 2020年第10期8卷 104-116页

作者： Marcus Vinicius de Mello pinto Carlos henrique Machado Bittencourt Silva Aline Ronis Sampaio Miriam Viviane Baron Alexandre Gomes Sancho Esteban Fortuny Lizia Fabiola almeida Silva Felice Picariello Rogério Mendonça de Carvalho Instituto Celulare Rio de Janeiro RJ Brazil Orthopedics Universidade Federal Fluminense (UFF) Rio de Janeiro RJ Brazil Post-Graduate Program in Medicine and Health Sciences Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) Porto Alegre RS Brazil Universidade do Grande Rio (Unigranrio) Rio de Janeiro RJ Brazil Universidad Finis Terrae Clínica Diagnostra Santiago do Chile Chile Brazilian National Research Ethics Committee (Conep) Brasília DF Brazil Università degli Studi di Napoli Federico II Naples Italy Universidade Federal de Uberlandia MG Brazil

Background: Photodynamic therapy (PDT) is the generation of cytotoxic agents through the dynamic interaction between a photosensitizer excited by light at a specific wavelength. When associated with phthalocyanines, they are efficient in incorporating target cells and exhibiting high rates of triplet generation. This study aimed to characterize PDT associated with the phototherapeutic agent Phthalomethyl D, developed by the authors, in the process of repair, healing and immune improvement for possible application against SARS-CoV-2. Methods: Sixty-nine mice were used, divided into 2 groups: GI, treated with ILIB laser, without a phototherapeutic agent, and subjected to surgery for viral induction;GII, same as GI plus association of Phthalomethyl D. They were divided into subgroups and reevaluated at 7, 14, and 21 days, and then divided into 3 subgroups of 6 animals each, subjected to treatment at 24 h, 48 h, 72 h, 5 and 7 days. Results: Both groups had a high rate of partial incision closure and acute inflammatory control. Microscopically, there was a greater amount of amorphous fundamental substance, fibrocytes, fibroblasts, and giant cells and reduction in the number of keratinocytes, in the amount of keratin, and epidermal thickness in GII than in GI. Conclusions: PDT with Phthalomethyl D stimulates the processes of healing/repair and immunomodulation during viral infection, initially favoring the inflammatory response and, after 21 days, contributing to the anti-inflammatory response profile, making this approach possible in the treatment of individuals infected with SARS-CoV-2.

关键词： Photodynamic Therapy Coronavirus Phthalocyanines Methylene Blue Vitamin D Phthalomethyl D

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Effects of intragastric balloon placement in metabolic dysfunctionassociated fatty liver disease: A systematic review and metaanalysis

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World Journal of Hepatology 2021年第7期13卷 815-829页

作者： João Remíde Freitas Júnior Igor Braga Ribeiro Diogo Turiani Hourneaux de Moura Vitor Massaro Takamatsu Sagae Gabriel Mayo Vieira de Souza Guilherme henrique Peixoto de Oliveira Sergio A Sánchez-Luna Thiago Ferreira de Souza Eduardo Turiani Hourneaux de Moura Cláudia pinto Marques Souza de Oliveira Wanderley Marques Bernardo Eduardo Guimarães Hourneaux de Moura Serviço de Endoscopia Gastrointestinal do Hospital das Clínicas HCFMUSP Departamento de GastroenterologiaFaculdade de MedicinaUniversidade de Sao PauloSao PauloSPBR Division of Gastroenterology and Hepatology Department of Internal MedicineBasil I.Hirschowitz Endoscopic Center of ExcellenceThe University of Alabama at BirminghamBirminghamAL 35294United States department of Gastroenterology Hospital das Clínicas da Faculdade de Medicina da Universidade de São PauloSão Paulo 05403-010Brazil

BACKGROUND Metabolic dysfunction-associated fatty liver disease corresponds to a clinical entity that affects liver function triggered by the accumulation of fat in the liver and is linked with metabolic *** To evaluate the effects of the intragastric balloon(IGB)in patients with metabolic dysfunction-associated fatty liver disease through the assessment of liver enzymes,imaging and several metabolic *** A comprehensive search was done of multiple electronic databases(MEDLINE,EMBASE,LILACS,Cochrane and Google Scholar)and grey literature from their inception until February *** criteria involved patients with a body mass index>25 kg/m2 with evidence or previous diagnosis of hepatic *** analyzed before and after 6 mo of IGB removal were alanine aminotransferase(IU/L),gamma-glutamyltransferase(IU/L),glycated hemoglobin(%),triglycerides(mg/dL),systolic blood pressure(mmHg),homeostatic model assessment,abdominal circumference(cm),body mass index(kg/m2)and liver volume(cm3).RESULTS Ten retrospective cohort studies evaluating a total of 508 patients were *** 6 mo of IGB placement,this significantly reduced alanine aminotransferase[mean difference(MD):10.2,95%confidence interval(CI):8.12-12.3],gammaglutamyltransferase(MD:9.41,95%CI:6.94-11.88),glycated hemoglobin(MD:0.17%,95%CI:0.03-0.31),triglycerides(MD:38.58,95%CI:26.65-50.51),systolic pressure(MD:7.27,95%CI:4.79-9.76),homeostatic model assessment(MD:2.23%,95%CI:1.41-3.04),abdominal circumference(MD:12.12,95%CI:9.82-14.41)and body mass index(MD:5.07,95%CI:4.21-5.94).CONCLUSION IGB placement showed significant efficacy in improving alanine aminotransferase and gamma-glutamyltransferase levels in patients with metabolic dysfunctionassociated fatty liver disease as well as improving metabolic markers related to disease progression.

关键词： Intragastric balloon Metabolic dysfunction-associated fatty liver disease Homeostatic model assessment Abdominal circumference Body mass index

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Technical Evaluation of Hybrid Clones of Corymbia spp. to Produce Market Pulp

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Paper And Biomaterials 2022年第3期7卷 1-6页

作者： Marcelo Moreira da Costa Ricardo de Carvalho Bittencourt Thales Augusto pinto Coelho Nogueira Larissa Soares Silva Weslley henrique Martins da Silva Sebastião Renato Valverde Gleison Augusto Dos Santos Daniel Alexander Fernandes Coelho Claudilene Aparecida Alves Pena department of Forest Sciences Federal University of VicosaVicosaMinas Gerais36570900Brazil Aperam BioEnergia Co. CapelinhaMinas Gerais39680000Brazil

This study presents hybrid clones of Corymbia *** by Aperam BioEnergia as potential substitutes for Eucalyptus wood in the pulp *** biomass of Eucalyptus *** compared with that of Corymbia *** performing modified kraft pulping and basic density *** were made by analyzing their respective mean annual increments of cellulose(MAI_(cel))and specific wood consumption(SWC),estimated using a kappa number of(19±1).The results showed that one of the hybrid clones(Corymbia citriodora×Corymbia torelliana,ID 4)had higher basic wood density,higher screened yield,better MAI_(cel#k19),and lower SWC than the other samples,reaching values of 0.608 t/m^(3),54.1%,24.6 ADt/ha/year(i.e.,air dry ton/hectare/year),and 2.74 m^(3)/ADt,***,clone ID 4 had the highest MAI_(cel)/SWC ratio score(8.98).Given its high forest productivity and low industrial cost compared with other samples,as well as its advantages over Eucalyptus ***,we concluded that clone ID 4 has great potential as an alternative biomass for pulp production.

关键词： Corymbia hybrids modified kraft pulping mean annual increments of cellulose(MAIcel) specific wood consumption(SWC)

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Corrosion behaviour of as-cast ZK40 with CaO and Y additions

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Transactions of Nonferrous Metals Society of China 2018年第3期28卷 427-439页

作者： Ricardo henrique BUZOLIN Marta MOHEDANO Chamini Lakshi MENDIS Beatriz MINGO Domonkos TOLNAI Carsten BLAWERT Karl Ulrich KAINER Haroldo pinto Norbert HORT Magnesium Innovation Centre Helmholtz-Zentrum Geesthacht Institute of Materials Science Joining and Forming Graz University of Technology departamento de Ciencia de Materiales Facultad de Ciencias Químicas Universidad Complutense Brunel Centre for Advanced Solidification Technology Brunel University London department of Materials Engineering University of Sao Paulo

The microstructures of as-cast ZK40,ZK40 with 2%(mass fraction)CaO and ZK40 with 1%(mass fraction)Y were investigated,and the intermetallic phase morphology and the distribution were *** having discrete intermetallic particles at the grain boundaries for the ZK40,the microstructure was modified to a semi-continuous network of intermetallic compounds along the grain boundaries for the ZK40 with CaO or Y *** CaO was not found in the ***,Ca was present in Ca2Mg6Zn3 intermetallic compounds which were formed during *** evolution and electrochemical impedance spectroscopy tests revealed that the addition of CaO slightly enhanced the corrosion resistance whereas Y had a negative effect on the corrosion resistance of *** tests showed that severe localised corrosion as well as corrosion along the intermetallic compounds played an important role in the corrosion process of ZK40-Y whereas the localised corrosion was not pronounced for ZK40 or ZK40?CaO ***-segregation in theα-Mg matrix was notably higher for the ZK40 alloy compared with the modified *** combination of this effect with a possible formation of a more stable corrosion layer for the ZK40-CaO was attributed as the main reason for an improved corrosion resistance for the ZK40-CaO alloy.

关键词： Mg alloy ZK40 Y addition CaO addition corrosion behaviour

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Study of Behavioral Changes and Photosynthetic Activity of <i>Euglenas gracilis</i>in the Presence of Effluents from the Laboratory of Clinical Analysis

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Journal of Environmental Protection 2020年第12期11卷 1015-1029页

作者： Luciano henrique pinto Suellen Zucco Bez Julia Carolina Soares Bruna Bonfim Qushmua Alzahrani Assistant Professor at the department of Pharmacy/Nursing/Medicine in UNIVILLE Joinville SC Brazil Student at the Pharmacy Course in UNIVILLE Joinville SC Brazil Voluntary Researcher in UNIVILLE Joinville SC Brazil

Healthcare waste has now been increasingly studied in terms of the risks or dangers that can cause the environment and human health. Waste generated in clinical analysis laboratories (CALs) deserves attention, because, due to the advent of the concept of emergent pollution, it is doubtful if the materials or reagents are disposed in the sewage by CALs, which are currently considered non-contaminated or with low risk potential, under current legislation, may actually impact the environment with actions not yet understood. This study was experimental and conducted at the Environmental Laboratory of the University of the Region of Joinville. It was used Euglena gracilis (primary trophic level) algae exposed to effluents from five sectors of a CAL: Biochemistry, Hematology, Viral Load, Tuberculosis and Immunochemistry. Samples were collected from the siphons attached to the wash sinks of the CAL materials. To verify changes in algae that denote environmental danger, behavioral changes were analyzed via NGTOX, and chlorophyll concentration was calculated by chlorophyll extraction according to Mendel’s method. Viral Load (VL) and Hematology (HT) sectors were the ones that most affected algae (Tukey test). In both sectors, there was inhibition of algae mobility and gravitaxy: in VL, due to the presence of chaotropic agents that denature organic structures;and in HT, due to the change in membrane permeability attributed to methylene blue. Also in HT, there was a search for algae adaptation by increasing the rise to the surface in order to overcome the lower luminosity due to the coloration of the environment, which also affects photosynthesis. Regarding the concentration of a-chlorophyll, the VL and HT were the most affected as well, being the first one the one that had more concentration reduction because of the presence of chaotropic agents. Considering new parameters evaluated, the discarded compounds need to be better evaluated for risk, as they affect algal photosynthe

关键词： Ecotoxicity Emerging Pollutants Chaotropic Agent Methylene Blue Effluent from Clinical Analysis Laboratory Residues

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Regression of Barrett＇s Esophagus： Is There a Difference between Clinical and Surgical Treatment？

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Journal of Pharmacy and Pharmacology 2017年第12期5卷 928-933页

作者： Ramon Rawache Barbosa Moreira de Lima Fernando Antonio Siqueira Pinheiro Joao Odilo Goncalves pinto Marcos Andre Araujo Accioly Filho Mateus Alves de Araujo Paulo henrique Araujo Parente department of Digestive Surgery Walter Cantideo University Hospital Federal University of Ceara Fortaleza 60430-380 Brazil

Objective： To evaluate the response to clinical and surgical treatment of Walter Cantidio University Hospital patients who were diagnosed with Barrett＇s esophagus between 2012 and 2016. Methodology： From the database analysis of Walter Cantidio University Hospital＇s pathology service, we identified all patients with a diagnosis of Barrett＇s esophagus between 2012 and 2016. We analyzed the patients＇ medical records and collected epidemiological and clinical data. Results： 22 patients were included in the study, 13 of whom were surgically treated and 9 were clinically treated. The regression was 33.3% in the clinical group and 30.7% in the surgical group, with no statistical difference between these two groups. Conclusions： The results show synchrony with data from the medical literature regarding the response of Barrett＇s esophagus to clinical and surgical treatment.

关键词： Barrett's esophagus treatment regression.

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