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Non-coding RNAs in acute ischemic stroke:from brain to periphery

Neural Regeneration Research 2025年第1期20卷 116-129页

作者： Shuo Li Zhaohan Xu Shiyao Zhang Huiling Sun Xiaodan Qin Lin zhu Teng Jiang Junshan Zhou Fuling Yan Qiwen Deng Department of Neurology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina Department of Neurology Zhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsu ProvinceChina General Clinical Research Center Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina

Acute ischemic stroke is a clinical emergency and a condition with high morbidity,mortality,and *** predictive,diagnostic,and prognostic biomarkers and effective therapeutic targets for acute ischemic stroke remain *** innovations in high-throughput gene sequencing analysis,many aberrantly expressed non-coding RNAs(ncRNAs)in the brain and peripheral blood after acute ischemic stroke have been found in clinical samples and experimental *** expressed ncRNAs in the post-stroke brain were demonstrated to play vital roles in pathological processes,leading to neuroprotection or deterioration,thus ncRNAs can serve as therapeutic targets in acute ischemic ***,distinctly expressed ncRNAs in the peripheral blood can be used as biomarkers for acute ischemic stroke prediction,diagnosis,and *** particular,ncRNAs in peripheral immune cells were recently shown to be involved in the peripheral and brain immune response after acute ischemic *** this review,we consolidate the latest progress of research into the roles of ncRNAs(microRNAs,long ncRNAs,and circular RNAs)in the pathological processes of acute ischemic stroke–induced brain damage,as well as the potential of these ncRNAs to act as biomarkers for acute ischemic stroke prediction,diagnosis,and *** from this review will provide novel ideas for the clinical application of ncRNAs in acute ischemic stroke.

关键词： acute ischemic stroke apoptosis blood–brain barrier damage circular RNAs excitatory toxicity long non-coding RNAs microRNAs neuroinflammation non-coding RNAs oxidative stress

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Research progress in metal-organic frameworks and their derivatives in electrochemistry

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Science China Chemistry 2025年

作者： Lingling Chen Yuxin Liu Yichun Su Wenchen zhu Guangyu Du Huan Pang School of Chemistry and Chemical Engineering Yangzhou University Department of Applied Physics The Hong Kong Polytechnic University Interdisciplinary Materials Research Center Institute for Advanced Study Chengdu University State Key Laboratory of Coordination Chemistry Nanjing University

Metal-organic frameworks (MOFs) are distinguished by their unique porosity and meticulously ordered framework structures,setting them apart from conventional complexes. These materials are defined by their highly organized crystalline and pore structures, extensive surface areas, robust porosity, and superior adsorption capabilities. Owing to their exceptional structural and functional attributes, MOFs and their derivatives are leveraged across a broad spectrum of applications, demonstrating significant potential across diverse sectors. In recent times, the scientific community has increasingly focused on MOFs, underscoring their growing importance in research. Despite the promising array of applications for MOFs and their derivatives,challenges persist in practical deployments, and the pathway to research advancement remains daunting. This document delves into the synthesis and various applications of MOFs and their derivatives, particularly in the domains of energy storage, catalysis,sensing, and water treatment. It also highlights the ongoing research progress in the field of electrochemistry, including developments in lithium ion batteries (LIBs), lithium-sulfur batteries (LSBs), zinc-ion batteries (ZIBs), aqueous nickel-zinc batteries (NZBs), and supercapacitors. Finally, it provides an outlook on the future prospects and potential hurdles facing the development of MOF materials.

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RE-SEGNN:recurrent semantic evidence-aware graph neural network for temporal knowledge graph forecasting

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Science China(Information Sciences) 2025年

作者： Wenyu CAI Mengfan LI Xuanhua SHI Yuanxin FAN Quntao zhu Hai JIN National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and TechnologyHuazhong University of Science and Technology

Temporal knowledge graph(TKG) reasoning, has seen widespread use for modeling real-world events, particularly in extrapolation settings. Nevertheless, most previous studies are embedded models, which require both entity and relation embedding to make predictions, ignoring the semantic correlations among different entities and relations within the same timestamp. This can lead to random and nonsensical predictions when unseen entities or relations occur. Furthermore, many existing models exhibit limitations in handling highly correlated historical facts with extensive temporal depth. They often either overlook such facts or overly accentuate the relationships between recurring past occurrences and their current counterparts. Due to the dynamic nature of TKG, effectively capturing the evolving semantics between different timestamps can be *** address these shortcomings, we propose the recurrent semantic evidenceaware graph neural network(RE-SEGNN), a novel graph neural network that can learn the semantics of entities and relations simultaneously. For the former challenge, our model can predict a possible answer to missing quadruples based on semantics when facing unseen entities or relations. For the latter problem, based on an obvious established force, both the recency and frequency of semantic history tend to confer a higher reference value for the current. We use the Hawkes process to compute the semantic trend, which allows the semantics of recent facts to gain more attention than those of distant facts. Experimental results show that RE-SEGNN outperforms all SOTA models in entity prediction on 6 widely used datasets, and 5 datasets in relation prediction. Furthermore, the case study shows how our model can deal with unseen entities and relations.

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(1-uv)-CONSTACYCLIC CODES OVER F_p+uF_p+vF_p+uvF_p

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Journal of Systems Science & Complexity 2014年第4期27卷 811-816页

作者： YU Haifeng zhu Shixin kai Xiaoshan Department of Mathematics and Physics Hefei University School of Mathematics Hefei University of Technology

Constacyclic codes are an important class of linear codes in coding *** optimal linear codes are directly derived from constacyclic *** this paper,(1 — uv)-constacyclic codes over the local ring F_p + uF_p + vF_p + uvF_p are *** is proved that the image of a(1 — uv)-constacyclic code of length n over F_p + uF_p + vF_p + uvF_p under a Gray map is a distance invariant quasi-cyclic code of index p2 and length p^3n over F_*** examples of optimal linear codes over F_p from(1 — uv)-constacyclic codes over F_p + uF_p + vF_p + uvF_p are given.

关键词： Constacyclic code cyclic code gray map quasi-cyclic code.

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Effect of methane-hydrogen mixtures on flow and combustion of coherent jets

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Journal of Iron and Steel Research International 2017年第11期24卷 1143-1151页

作者： Ting Cheng Rong zhu kai Dong School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Beijing Key Laboratory of Research Center of Special Melting and Preparation of High-end Metal Materials University of Science and Technology BeijingBeijing 100083China

Coherent jets are widely used in electric are furnace （EAF） steelmaking to increase the oxygen utilization and chemical reaction rates. However, the influence of fuel gas combustion on jet behavior is not fully understood yet. The flow and combustion characteristics of a coherent jet were thus investigated at steelmaking temperature using Fluent software, and a detailed chemical kinetic reaction mecha- nism was used in the combustion reaction model. The axial velocity and total temperature of the supersonic jet were measured via hot state experiments. The simulation results were compared with the experimental data and the empirical jet model proposed by Ito and Muchi and good consistency was obtained. The research results indicated that the potential core length of the coherent jet can be prolonged by optimizing the combustion effect of the fuel gas. Besides, the behavior of the supersonic jet in the subsonic section was also investigated, as it is an important factor for controlling the position of the oxygen lance. The investigation indicated that the attenuation of the coherent jet is more notable than that of the conventional jet in the subsonic section.

关键词： Supersonic jet Numerical simulation Mixed fuel gas Flow field Combustion characteristic

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Aligning enhanced feature representation for generalized zero-shot learning

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Science China(Information Sciences) 2025年

作者： Zhiyu FANG Xiaobin zhu Chun YANG Hongyang ZHOU Jingyan QIN Xucheng YIN School of Computer&Communication Engineering University of Science and Technology Beijing

Abstract Constructing an effective common latent embedding by aligning the latent spaces of cross-modal variational autoencoders （VAEs） is a popular strategy for generalized zero-shot learning （GZSL）.However,due to the lack of fine-grained instance-wise annotations,existing VAE methods can easily suffer from the posterior collapse *** this paper,we propose an innovative asymmetric VAE network by aligning enhanced feature representation （AEFR） for *** from general VAE structures,we designed two asymmetric encoders for visual and semantic observations and one decoder for visual ***,we propose a simple yet effective gated attention mechanism （GAM） in the visual encoder for enhancing the information interaction between observations and latent variables,alleviating the possible posterior collapse problem *** addition,we propose a novel distributional decoupling-based contrastive learning （D2-CL） to guide learning classification-relevant information while aligning the representations at the taxonomy level in the latent representation *** experiments on publicly available datasets demonstrate the state-of-the-art performance of our *** source code is available at https://***/seeyourmind/AEFR.

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Effects on the mixing process of a coiled tube after a T-junction:Simulation and correlation

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Chinese Journal of Chemical Engineering 2018年第12期26卷 2441-2447页

作者： Shan zhu kai Wang Yangcheng Lü State Key Laboratory of Chemical Engineering Department of Chemical Engineering Tsinghua University

Simulations were performed to examine the effects of a coiled tube after a T-junction on the mixing and flow characteristics. A coiled tube was found to have two effects: inducing a radial flow and flattening the axial velocity distribution, which enhances and weakens the mixing, respectively. In the straight tube section connecting the Tjunction and coiled tube, the latter may dominate and cause the mixing to deteriorate. An experiment was performed with the Villermaux/Dushman method to verify the simulation results. Based on a mixing performance simulation with various fluid and geometric structure parameters, a dimensionless correlation was obtained that can be used to determine the mixing intensity along the coiled tube with a deviation of less than 1.5%.These results provide guidance for designing a coiled tube or optimizing the operating conditions to meet the mixing requirements of specific chemical processes.

关键词： Mixing T-junction Simulation Coiled tube Correlation Flow

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Fusion of Gaussian Mixture Models for Maneuvering Target Tracking in the Presence of Unknown Cross-correlation

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Chinese Journal of Electronics 2016年第2期25卷 270-276页

作者： zhu Hongyan GUO kai CHEN Shuo School of Electronic and Information Engineering Xi'an Jiaotong University China Electronics Technology Group Corporation No.28 Research Institute

The paper addresses the problem of estimation fusion for maneuvering target tracking in the presence of unknown cross-correlation. To improve the fusion accuracy, two major points are concerned. Firstly, the Interacting multiple model(IMM) estimator is performed for each sensor, and the local estimate is represented by a Gaussian mixture model instead of a Gaussian density to keep more details of the local tracker. Next, a close-formed solution of fusing two Gaussian mixtures in the Covariance intersection(CI) framework is derived to cope with the unknown cross-correlation of local estimation errors. Experimental results demonstrate that the proposed approach provides some improvements in the fusion accuracy over the competitive methods.

关键词： Gaussian mixture model(GMM) Estimation fusion Interacting multiple model(IMM) Covariance intersection(CI) Cross-correlation

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On the Gray Images of Some Constacyclic Codes over Fp ＋ uFp ＋ u^2Fp

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Journal of Systems Science & Complexity 2016年第3期29卷 842-849页

作者： YU Haifeng zhu Shixin kai Xiaoshan Department of Mathematics and Physics Hefei University Hefei 230601 China. School of Mathematics Hefei University of Technology Hefei 230009 China National Mobile Communications Research Laboratory Southeast University Nanjinq 210096 China.

Abstract Constacyclic codes are an important class of linear codes in coding theory. Many optimal linear codes are directly derived from constacyclic codes. In this paper, a new Gray map between codes over Fp ＋ uFp ＋ u^2Fp and codes over Fp is defined, where p is an odd prime. By means of this map, it is shown that the Gray image of a linear （1 ＋ u ＋ u2）-constacyclic code over Fp ＋ uFp ＋ u^2Fp of length n is a repeated-root cyclic code over Fp of length pn. Furthermore, some examples of optimal linear cyclic codes over F3 from （1 ＋ u ＋ u2）-constacyclic codes over F3 ＋ uF3 ＋ u^2F3 are given.

关键词： Constacyclic code cyclic code Gray map.

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Facile room-temperature coprecipitation of uniform barium chlorapatite nanoassemblies as a host photoluminescent material

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Particuology 2018年第2期16卷 37-42页

作者： Peiyan Zhai Xiuping Chen Zhaoqiang Zhang Lin zhu heng Zhang Wancheng zhu Department of Chemical Engineering Qufu Normal University Shandong 273165 China

As an emerging host phosphor material, barium chlorapatite （Bas（PO4）3CI）, is attracting growing attention. However, rare earth-doped Bas（PO4）3CI phosphors have mainly been obtained via high temperature-based, energy-consuming techniques. In this contribution, we developed a straight- forward, facile room-temperature coprecipitation method in the presence of a specific amount of ethylenediaminetetraacetic acid disodium salt that provided Bas（PO4）3CI nanoparticles self-assembled to construct uniform Bas（PO4）3CI nanoassemblies （diameter： 80-120 nm） as well as rare earth Tb3＋- doped Bas（PO4）3CI：xTb3＋ nanophosphors. The nanoassemblies were transparent within the ultraviolet and visible spectral range. The Bas（PO4）3CI：xTb3＋ nanophosphors exhibited four emission peaks under 228-nm excitation, and the optimal doping amount of Tb3＋ was 4.0%. In contrast to traditional energy-consuming, high-temperature techniques, the facile room-temperature coprecipitation method developed here represents an attractive alternative route to obtain uniform Ba5（PO4）3CI nanoassemblies and Bas（PO4）3CI：xTb3＋ nanopbosphors that are candidate luminescent hosts.

关键词： Barium chlorapatite Nanoassemblies Phosphors Luminescence Room-temperature coprecipitation

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