检索结果-南通市图书馆

Genetic diversity of food-medicinal Lycium *** China:Insights from chloroplast genome

Chinese Herbal Medicines 2024年第3期16卷 401-411页

作者： Ruyu Yao Bin Wang Michael heinrich Qiuling Wang Peigen Xiao Institute of Medicinal Plant Development Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100193China Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine Hainan Branch of the Institute of Medicinal Plant DevelopmentChinese Academy of Medical Sciences and Peking Union Medical CollegeHaikou 570311China Research Group‘Pharmacognosy and Phytotherapy’ UCL School of PharmacyUniversity of LondonLondon WC1N1AXUnited Kingdom Kunming Institute of Botany Chinese Academy of SciencesKunming 650201China

Objective:Goji(fruits of Lycium spp.)is commonly consumed as food and *** increasing market demand for goji has led to its wide cultivation and broad breeding,which might cause loss of genetic *** study aims to uncover the genetic diversity of the cultivated and wild ***:The chloroplast genome(CPG)of 34 accessions of Chinese food-medicinal Lycium spp.,including the popular cultivars and their wild relatives,was re-sequenced and assembled,based on which the genetic diversity was ***:Sequence structural comparison shows that CPG is comparatively conserved within *** analysis indicates that CPG is sufficient for the discrimination of Lycium species;combined with nuclear ribosomal internal transcribed spacer(nr ITS)sequences,materials with mixed genetic backgrounds can be *** diversity analysis reveals that the modern cultivars are probably with a common maternal parent,while the wild accessions are with higher level of genetic ***:For the first time this study reveals the intraspecies genetic diversity of Lycium *** CPG,highlighting the urgent conservation demand of wild genetic resources of *** study also demonstrates that CPG provides crucial evidence for identification of Lycium species with mixed genetic backgrounds and highlights the importance of the wild relatives in genetic diversity *** CPG-based technology will contribute to the sustainable development of medicinal plants broadly.

关键词： chloroplast genome cultivar food-medicine genetic diversity goji wild relative

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Remote sensing to detect deterioration of Flooding Pampa rangeland by the use of glyphosate

Remote sensing to detect deterioration of Flooding Pampa ran...

引用

ⅩⅪ International Grassland Congress and the Ⅷ International Rangeland Congress

作者： Jacobo,E Rodriguez,A heinrich,n Facultad,L Universidad de Buenos Aires.Av.San Martin 4453 Buenos Aires 1417 Argentina

Introduction A technique based on spraying glyphosate to Flooding Pampa’s rangelands in late summer has been widespread during the last *** technique eliminates green vegetation growing in late summer with the aim of improve germination and establishment of cool season(C) annual grasses,which,in turn,increases winter forage offer and allows increment of

关键词： temperate grasslands photosynthetically active radiation absorbed seasonal variation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Characterization of bright betatron radiation generated by direct laser acceleration of electrons in plasma of near critical density

引用

Matter and Radiation at Extremes 2024年第2期9卷 26-35页

作者： J.Cikhardt M.Gyrdymov S.Zähter P.Tavana M.M.Günther n.Bukharskii n.Borisenko J.Jacoby X.F.Shen A.Pukhov n.E.Andreev O.n.Rosmej Faculty of Electrical Engineering Czech Technical University in Prague16627 Prague 6Czech Republic Goethe University FrankfurtMax-von-Laue-Straße 160438 Frankfurt am MainGermany GSI Helmholtzzentrum für Schwerionenforschung GmbH Planckstraße 164291 DarmstadtGermany Focused Energy GmbH Im Tiefen See 4564293 DarmstadtGermany national Research nuclear University MEPhI Kashirskoe shosse 31115409 MoscowRussian Federation Lebedev Physical Institute RAS Leninskiy Prospekt 53119991 MoscowRussian Federation heinrich-Heine-University Düsseldorf Universitätsstrasse 1DüsseldorfGermany Joint Institute for High Temperatures RASIzhorskaya st.13Bldg.2125412 MoscowRussian Federation Moscow Institute of Physics and Technology Institutskiy Pereulok 9141700 DolgoprudnyRussia

Directed x-rays produced in the interaction of sub-picosecond laser pulses of moderate relativistic intensity with plasma of near-critical density are investigated. Synchrotron-like (betatron) radiation occurs in the process of direct laser acceleration (DLA) of electrons in a relativisticlaser channel when the electrons undergo transverse betatron oscillations in self-generated quasi-static electric and magnetic fields. In anexperiment at the PHELIX laser system, high-current directed beams of DLA electrons with a mean energy ten times higher than the ponderomotive potential and maximum energy up to 100 MeV were measured at 10^(19) W/cm^(2)laser intensity. The spectrum of directed x-raysin the range of 5–60 keV was evaluated using two sets of Ross filters placed at 0°and 10°to the laser pulse propagation axis. The differential x-ray absorption method allowed for absolute measurements of the angular-dependent photon fluence. We report 10^(13) photons/sr withenergies >5 keV measured at 0°to the laser axis and a brilliance of 10^(21) photons s^(−1) mm^(−2) mrad−2(0.1%BW)−1. The angular distributionof the emission has an FWHM of 14°–16°. Thanks to the ultra-high photon fluence, point-like radiation source, and ultra-short emissiontime, DLA-based keV backlighters are promising for various applications in high-energy-density research with kilojoule petawatt-class laserfacilities.

关键词： laser acceleration critical

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optimizing laser coupling,matter heating,and particle acceleration from solids using multiplexed ultraintense lasers

引用

Matter and Radiation at Extremes 2024年第4期9卷 16-28页

作者： Weipeng Yao Motoaki nakatsutsumi Sébastien Buffechoux Patrizio Antici Marco Borghesi Andrea Ciardi Sophia n.Chen Emmanuel d’Humières Laurent Gremillet Robert Heathcote Vojtech Horny Paul McKenna Mark n.Quinn Lorenzo Romagnani Ryan Royle Gianluca Sarri Yasuhiko Sentoku Hans-Peter Schlenvoigt Toma Toncian Olivier Tresca Laura Vassura Oswald Willi Julien Fuchs LULI-CnRS CEASorbonne UniversitéEcole PolytechniqueInstitut Polytechnique de ParisF-91128 Palaiseau CedexFrance Sorbonne Université Observatoire de ParisUniversité PSLCNRSLERMAF-75005 ParisFrance InRS-EMT 1650 BoulLionel-BouletVarennesQuebec J3X 1S2Canada Center for Plasma Physics School of Mathematics and PhysicsQueen’s University BelfastBelfast BT71NNUnited Kingdom “Horia Hulubei”national Institute for Physics and nuclear Engineering 30 Reactorului StreetRO-077125 Bucharest-MagureleRomania University of Bordeaux Centre Lasers Intenses et ApplicationsCNRSCEAUMR 5107F-33405 TalenceFrance CEA DAMDIFF-91297 ArpajonFrance Université Paris-Saclay CEALMCE91680 Bruyères-le-ChatelFrance Central Laser Facility STFC Rutherford Appleton LaboratoryDidcotUnited Kingdom SUPA Department of PhysicsUniversity of StrathclydeGlasgow G40NGUnited Kingdom Department of Physics University of NevadaRenoNevada 89557USA Institute of Laser Engineering Osaka University2-6 YamadaokaSuitaOsaka 565-0871Japan Institut fur Laser und Plasmaphysik Heinrich Heine Universitat DusseldorfDusseldorfGermany

Realizing the full potential of ultrahigh-intensity lasers for particle and radiation generation will require multi-beam arrangements due to technology ***,we investigate how to optimize their coupling with solid ***,we show that overlapping two intense lasers in a mirror-like configuration onto a solid with a large preplasma can greatly improve the generation of hot electrons at the target front and ion acceleration at the target *** underlying mechanisms are analyzed through multidimensional particle-in-cell simulations,revealing that the self-induced magnetic fields driven by the two laser beams at the target front are susceptible to reconnection,which is one possible mechanism to boost electron *** addition,the resistive magnetic field generated during the transport of the hot electrons in the target bulk tends to improve their *** simulations also indicate that such effects can be further enhanced by overlapping more than two laser beams.

关键词： laser acceleration particle

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Four-wheel-drive immune protection

引用

Signal Transduction and Targeted Therapy 2022年第10期7卷 3637-3638页

作者： Fabian heinrich Susanne Krasemann Institute of Legal Medicine University Medical Center Hamburg Eppendorf20251 HamburgGermany Institute of neuropathology University Medical Center Hamburg Eppendorf20251 HamburgGermany

In a recent study published in Cell,Zhang and colleagues provide the first longitudinal study comparing four different COVID-19 vaccines head-to-head for binding and neutralizing antibodies,spike-specific CD4+or CD8+T... 详细信息

关键词： antibodies immune vaccines

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Reinforcement Learning approach for the continuous electricity market ofGermany: Trading from the perspective of a wind park operator

引用

能源与人工智能(英文) 2022年第2期8卷 67-78页

作者： Malte Lehna Björn Hoppmann Christoph Scholz Renéheinrich Fraunhofer Institute for Energy Economics and Energy System Technology(IEE) Königstor 5934119 KasselGermany

With the rising extension of renewable energies, the intraday electricity markets have recorded a growingpopularity amongst traders as well as electric utilities to cope with the induced volatility of the energysupply. Through their short trading horizon and continuous nature, the intraday markets offer the abilityto adjust trading decisions from the day-ahead market or reduce trading risk in a short-term notice. Producersof renewable energies utilize the intraday market to lower their forecast risk, by modifying their providedcapacities based on current forecasts. However, the market dynamics are complex due to the fact that thepower grids have to remain stable and electricity is only partly storable. Consequently, robust and intelligenttrading strategies are required that are capable to operate in the intraday market. In this work, we proposea novel autonomous trading approach based on Deep Reinforcement Learning (DRL) algorithms as a possiblesolution. For this purpose, we model the intraday trade as a Markov Decision Process (MDP) and employ theProximal Policy Optimization (PPO) algorithm as our DRL approach. A simulation framework is introducedthat enables the trading of the continuous intraday price in a resolution of one minute steps. We test ourframework in a case study from the perspective of a wind park operator. We include next to general tradeinformation both price and wind forecasts. On a test scenario of German intraday trading results from 2018,we are able to outperform multiple baselines with at least 45.24% improvement, showing the advantage of theDRL algorithm. However, we also discuss limitations and enhancements of the DRL agent, in order to increasethe performance in future works.

关键词： Deep Reinforcement Learning German intraday electricity trading Deep neural networks Markov Decision Process Proximal Policy Optimization Electricity price forecast

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高剂量利福平、莫西沙星和SQ109治疗肺结核：一项多组别、多阶段的随机对照试验

引用

中国防痨杂志 2017年第7期39卷 756-756页

作者： Boeree MJ heinrich n Aarnoutse R 申晓娜孙勤不详同济大学附属上海市肺科医院结核病临床研究中心上海市结核(肺)重点实验室

背景结核病是世界传染病死亡的第一杀手,目前结核病治疗仍需要至少6个月的疗程,本临床试验旨在研究更短,更安全的敏感性结核病治疗方案.

关键词：治疗方案随机对照试验莫西沙星利福平高剂量肺结核结核病临床试验

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A small,polyphyletic group of Firmicutes synthesizes trimethylamine from L-carnitine

引用

mLife 2023年第3期2卷 267-271页

作者： Marius Vital Ylenia heinrich-Sanchez Hannover Medical School Institute for Medical Microbiology and Hospital EpidemiologyHannoverGermany

Impact statement Gut microbiota-derived trimethylamine(TMA)is associated with cardiometabolic disorders and exemplifies a microbial involvement in the etiology of emerging,noncommunicable diseases,the leading causes of death *** bio-chemical pathways taking dietary compounds as intake have been described with distinct taxa involved that are all present at low relative abundances.A recently discovered pathway is now considered to be the main route for TMA synthesis from L-carnitine involvingγ-butyrobetaine as an intermediate *** comprehensive(meta)genomic screening of publicly available data,namely,genomes of the UHGG catalog(n>200,000)and 10 metagenomic(transcriptomic)data sets,we revealed bacteria synthesizing TMA via this pathway and specified their *** will contribute to stratification of individuals based on their gut microbiota's potential to synthesize TMA and might aid in the development of strategies restricting TMA formation.

关键词： product. synthesize statement

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

大剂量利福平、莫西沙星和SQ109治疗结核病:一项多臂、多阶段随机对照试验

引用

结核病与肺部健康杂志 2017年第3期6卷 293-293页

作者： Boeree MJ heinrich n Aarnoutse R 常蕴青山西省太原市第四人民医院

背景结核病是目前世界上最主要的传染病杀手,抗结核药物治疗方案至少持续6个月.因此,制定更短、更安全、更有效的抗结核药物治疗方案是终止结核病的全球战略之一.既往的研究表明,大剂量利福平(35mg· kg 1·d1)是安全的,并且能够增加...

背景结核病是目前世界上最主要的传染病杀手,抗结核药物治疗方案至少持续6个月.因此,制定更短、更安全、更有效的抗结核药物治疗方案是终止结核病的全球战略之一.既往的研究表明,大剂量利福平(35mg· kg 1·d1)是安全的,并且能够增加痰菌阴转率,提高结核病的治愈率,是短程化疗的重要组成部分.该研究旨在进一步评估大剂量利福平治疗初治肺结核的有效性和安全性.

关键词：

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Retinal microvascular signs and recurrent vascular events in patients with TIA or minor stroke

引用

Stroke & Vascular neurology 2023年第5期8卷 379-386,I0001-I0007页

作者： Philipp Klyscz Thomas Ihl Inga Laumeier Maureen Steinicke Matthias Endres Georg Michelson heinrich J Audebert neurology Charité-Universitätsmedizin BerlinBerlinGermany Center for Stroke Research Berlin Charité-Universitätsmedizin BerlinBerlinGermany Berlin Institute of Health BerlinGermany Excellence Cluster neuroCure Charité-Universitätsmedizin BerlinBerlinGermany German Center for neurodegenerative Diseases partner site BerlinGermany German Center for Cardiovascular Research partner site BerlinGermany Ophthalmology Friedrich-Alexander-Universität Erlangen-Nürnberg Medizinische FakultätErlangenGermany Talkingeyes&More GmbH ErlangenGermany

Background and purpose Retinal pathologies are an independent risk factor for ischaemic stroke,but research on the predictive value of retinal abnormalities for recurrent vascular events in patients with prior stroke is *** investigated the association of retinal pathologies with subsequent vascular *** In a substudy of the Intensified secondary prevention intending a reduction of recurrent events in TIA and minor stroke patients(InSPiRE-TMS)trial,we enrolled patients with recent transient ischaemic attack(TIA)or minor stroke with at least one modifiable risk *** outcome was the composite of subsequent vascular *** photographs were taken at baseline and categorised into three different fundus groups by a telemedically linked *** 722 patients participated in the current study and 109 major vascular events *** multivariable adjustments,we did not find a significant association between fundus categories and risk for subsequent vascular events(HRs for moderate vascular retinopathy and vascular retinopathy with vessel rarefaction in comparison to no vascular retinopathy 1.03(95%CI 0.64 to 1.67),p=0.905 and 1.17(95%CI 0.62 to 2.20),p=0.626).In a selective post hoc analysis in patients with diabetes mellitus and hypertension,patients with vascular retinopathy with vessel rarefaction had a higher risk for recurrent stroke(HR 24.14(95%CI 2.74 to 212.50),p=0.004).Conclusions Retinal changes did not predict major subsequent vascular events in patients with recent TIA or minor *** studies are needed to examine the utility of fundus photography in assessing the risk of stroke recurrence in patients with diabetes mellitus and hypertension.

关键词： patients Retinal prevention

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：