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World Journal of Clinical Cases 2020年第21期8卷 5347-5352页

作者： hee jeong Lee Sang-Gon Park Department of Hemato-Oncology Chosun University HospitalGwang-ju 501-717South Korea Department of Internal Medicine Hemato-oncologyChosun University HospitalGwangju 61453South Korea

BACKGROUND Arsenic trioxide(ATO)is recommended for patients who do not achieve molecular remission or who have molecular or morphologic ***,there are no guidelines for adjusting ATO dosage in patients with severe renal failure or on ***,we report the successful treatment of relapsed acute promyelocytic leukemia(APL)in a patient on hemodialysis with ATO single agent and review the cases in *** SUMMARY A 46-year-old woman who has been on hemodialysis to chronic glomerulonephritis for 15 years visited our hospital for *** had been seen for pancytopenia 3 years ago and had been diagnosed with *** also received chemotherapy for APL but unfortunately was lost to follow-up after her second consolidation *** was noted to have pancytopenia by her nephrologist during hemodialysis 1 mo *** marrow biopsy and reverse transcriptase-polymerase chain reaction(RT-PCR)tests revealed a diagnosis of relapsed *** for relapsed APL with ATO single agent was started and she achieved molecular remission after administering 24 doses of *** far,four consolidation therapies have been performed with the ATO single agent,and,to date,the molecular remission has been maintained as negative promyelocytic leukemia/retinoic acid receptor-αfusion gene as confirmed by RTPCR testing for two *** This is a rare case of relapsed APL successfully treated with the single agent ATO in a patient on hemodialysis.

关键词： Arsenic trioxide Acute promyelocytic leukemia Pancytopenia Hemodialysis Promyelocytic leukemia/retinoic acid receptor-αfusion gene Case report

Attaching single carbon nanotube on tip's apex using dielectrophoresis of DC-pulse voltage

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中国有色金属学会会刊：英文版 2009年第B9期19卷 280-283页

作者： hee-Jin jeong Yoong-Ho JUNG Deug-Woo LEE Gyeongbuk Hybrid Technology Institute School of Mechanical Engineering Pusan National University Department of Nanosystem and Nanoprocess Engineering Pusan National University

Single carbon nanotubes (CNTs) are candidates for a number of electronics and sensing applications, provided that single CNTs can be separated from a bundle of CNTs in suspension. Dielectrophoresis has recently been demonstrated as one route for the extraction of desired CNTs. However, previous methods using dielectrophoresis have found it difficult to extract single nanotubes from bundles of CNTs in solution. Here, we show that this restriction can be overcome by using pulsed DC voltage of an electric field, instead of regular AC and DC voltages.

关键词：碳纳米管直流脉冲脉冲电压介电顶点消息电子号码 CNTs

Micro-accelerometer Based on Vertically Movable Gate Field Effect Transistor

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Nano-Micro Letters 2015年第3期7卷 282-290页

作者： Heung seok Kang Kang-hee Lee Dong-Youk Yang Byoung hee You In-Hyouk Song Korea Atomic Energy Research Institute LOGTECH Co. Ltd 914 Gumgang Hightech Valley 1st Department of Engineering Technology Texas State University601 University Dr. San Marcos TX 78666 USA

A vertically movable gate field effect transistor(VMGFET) is proposed and demonstrated for a microaccelerometer application. The VMGFET using air gap as an insulator layer allows the gate to move on the substrate vertically by external forces. Finite element analysis is used to simulate mechanical behaviors of the designed structure. For the simulation, the ground acceleration spectrum of the 1952 Kern County Earthquake is employed to investigate the structural integrity of the sensor in vibration. Based on the simulation, a prototype VMGFET accelerometer is fabricated from silicon on insulator wafer. According to current–voltage characteristics of the prototype VMGFET, the threshold voltage is measured to be 2.32 V, which determines the effective charge density and the mutual transconductance of1.545910-8C cm-2and 6.59 m A V-1, respectively. The device sensitivity is 9.36–9.42 m V g-1in the low frequency,and the first natural frequency is found to be 1230 Hz. The profile smoothness of the sensed signal is in 3 d B range up to1 k Hz.

关键词： MEMS Micro-accelerometer Suspended gate FET Vertically movable gate FET VMGFET

Effects of ozonation and coagulation on effluent organic matter characteristics and ultrafiltration membrane fouling

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Journal of Environmental Sciences 2014年第6期26卷 1325-1331页

作者： Kwon jeong Dae-Sung Lee Do-Gun Kim seok-Oh Ko Department of Civil Engineering Kyung Hee UniversityYongin 446-701 Korea Institute of Construction Technology KUMHO Engineering & ConstructionYongin 449-822 Korea

Effluent organic matter （EfOM） is the major cause of fouling in the low pressure membranes process for wastewater reuse. Coagulation and oxidation of biological wastewater treatment effluent have been applied for the fouling control of microfiltration membranes. However, the change in EfOM structure by pre-treatments has not been clearly identified. The changes of EfOM characteristics induced by coagulation and ozonation were investigated through size exclusion chromatography, UV/Vis spectrophotometry, fluorescence spectrophotometry and titrimetric analysis to identify the mechanisms in the reduction of ultrafiltration （UF） membrane fouling. The results indicated that reduction of flux decline by coagulation was due to modified characteristics of dissolved organic carbon （DOC） content. Total concentration of DOC was not reduced by ozonation. However, the mass fraction of the molecules with molecular weight larger than 5 kDa, fluorescence intensity, aromaticity, highly condensed chromophores, average molecular weight and soluble microbial byproducts decreased greatly after ozonation. These results indicated that EfOM was partially oxidized by ozonation to low molecular weight, highly charged compounds with abundant electron- withdrawing functional groups, which are favourable for alleviating UF membrane flux decline.

关键词： effluent organic matter fouling ultrafiltration oxidation molecular weight distribution acidity

Synthesis and Characterization of Fluoro- and Chloro-bimetallic Alkoxides as Precursors for Luminescent Metal Oxide Materials via Sol-Gel Technique

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Chinese Journal of Chemistry 2007年第7期25卷 998-1004页

作者： ATHAR.Taimur seok, Sang II KWON, jeong Oh Indian Institute of Chemical Technology Uppal Road Tarnaka Hyderabad (A.P.) 500007 India Advanced Materials Division Korea Research Institute of Chemical Technology 100 Jang-Dong Yuseong-Gu Daejon 305-343 Korea

Heterobimetallic alkoxides are broadly recognized as versatile precursors for luminescence materials, and efforts are being made to develop novel routes by applying the concept of geometrical molecular design, for their synthesis and to design a single source precursor suited to photoluminescent materials. Novel and new series of bimetallic alkoxides has been prepared by metathesis route. They exhibit a lower sensitivity towards hydrolysis and so they are easier to handle as compared to other alkoxides. All the compounds were characterized by elemental analysis, FT-IR and multinuclear NMR spectroscopies. FT-IR revealed that the molecular structure of these metal alkoxides was retained to a large extent in 4 ： 1 halogenated alcohol-benzene solution. The heteronuclear NMR spectroscopy provided useful information about chemical shifts for better understanding the likely structure based on interactions with their coordinate metals. The mass spectra show similar types of fragmentation pattern. SEM-EDS analyses showed consistency with the formulation. XRD patterns show an enhanced homogeneity at high temperature. TGA measurements show that thermal decomposition occured in steps that depended entirely on the chemical compositions and the synthesis routes. SEM observation reveals that the morphology and particle size strongly depend on synthesis routes for their precursors.

关键词： precursor chemistry fluoro- or chloro-bimetallic alkoxide geometric design luminescent material

Fuzzy logic controller design with unevenly-distributed membership function for high performance chamber cooling system

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Journal of Central South University 2014年第7期21卷 2684-2692页

作者：曹健鹏 seok-Kwon jeong Young-Mi Jung Graduate School of Refrigeration and Air-conditioning Engineering Pukyong National University Department of Refrigeration and Air-conditioning Engineering Pukyong National University

Fuzzy logic controller adopting unevenly-distributed membership function was presented with the purpose of enhancing performance of the temperature control precision and robustness for the chamber cooling *** equalization and noise detection were performed to modify the evenly-distributed membership functions of error and error change rate into unevenly-distributed membership ***,the experimental results with evenly and unevenly distributed membership functions were compared under the same outside environment *** experimental results show that the steady-state error is reduced around 40% and the noise disturbance is rejected successfully even though noise range is 60% of the control precision *** control precision is improved by reducing the steady-state error and the robustness is enhanced by rejecting noise disturbance through the fuzzy logic controller with unevenly-distributed membership ***,the system energy efficiency and lifetime of electronic expansion valve(EEV) installed in chamber cooling system are improved by adopting the unevenly-distributed membership function.

关键词： chamber cooling system fuzzy logic controller unevenly-distributed membership function steady-state error reduction robustness variable speed refrigeration system

Prevalence of coronavirus from diarrheic calves in the Republic of Korea

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Asian Pacific Journal of Tropical Biomedicine 2018年第1期8卷 1-6页

作者： Jinho Park Du-Gyeong Han Su hee Kim jeong-Byoung Chae Joon-seok Chae Do-Hyeon Yu Kyoung-Seong Choi College of Veterinary Medicine Chonbuk National University Department of Animal Science and Biotechnology College of Ecology and Environmental Science Kyungpook National University Animal Disease & Biosecurity Team National Institute of Animal Science Rural Development Administration Laboratory of Veterinary Internal Medicine BK21 PLUS Program for Creative Veterinary Science Research Research Institute for Veterinary Science and College of Veterinary Medicine Seoul National University College of Veterinary Medicine Gyeongsang National University

Objective: To investigate the prevalence of bovine coronavirus(BCo V), bovine rotavirus, and bovine viral diarrhea virus in the feces of normal and diarrheic Korean native calves aged 1-81 days between April and October of 2016 in the Republic of Korea. Methods: Samples were obtained from 50 normal and 93 diarrheic(56 semi-formed, 28 loose, and 9 watery feces) calves in six different regions of northern and southern Korea. These fecal samples were tested for BCo V, bovine rotavirus, and bovine viral diarrhea virus by RT-PCR. Results: Among the three pathogens examined, infection with BCo V was especially prominent in relation to diarrhea among calves aged 1-21 days [odds ratio(OR)=9.3, 95% confidence interval(CI): 1.1-78.9; P=0.02). Infection with BCo V alone(OR=2.9; 95% CI: 1.1-7.6; P=0.03) or coinfection of BCo V with bovine viral diarrhea virus(OR=3.6; 95% CI: 1.0-12.4; P=0.04) was significantly associated with the development of loose feces. Grazing and colostrum intake strongly reduced the occurrence of diarrhea as compared to housed calves(OR=0.2; 95% CI: 0.1-0.4; P=0.00) and calves that had not been fed colostrum(OR=0.2; 95% CI: 0.1-0.7; P=0.02), respectively. Conclusions: The present study suggests that BCo V is involved in calf diarrhea in the Republic of Korea. Therefore, grazing and colostrum intake is recommended for preventing and controlling calf diarrhea caused by BCoV.

关键词： Calf diarrhea Bovine coronavirus Bovine viral diarrhea virus Loose feces Grazing

Risk factors and therapeutic results of early local recurrence after transcatheter arterial chemoembolization

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World Journal of Gastroenterology 2014年第22期20卷 6995-7004页

作者： Woo Sun Rou Byung seok Lee hee seok Moon Eaum seok Lee seok Hyun Kim Heon Young Lee Division of Gastroenterology Department of Internal MedicineChungnam National University College of MedicineDaejeon 301-721South Korea Division of Gastroenterology Department of Internal MedicineChungnam National University College of MedicineDaejeon 301-721South Kore

AIM: To identify factors affecting early local recurrence after transcatheter arterial chemoembolization (TACE) and investigate treatments and outcomes for local recurrence.

关键词： Chemoembolization Hepatocellular carcinoma Recurrence Survival Lipiodol

Risk stratification for disease progression in pT3 prostate cancer after robot-assisted radical prostatectomy

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Asian Journal of Andrology 2017年第6期19卷 700-706页

作者： jeong hee Hong Young Suk Kwon Isaac Yi Kim Section of Urologic Oncology Rutgers Cancer Institute of New Jersey Division of Urology Rutgers Robert Wood Johnson Medical School Rutgers The State University of New Jersey New Brunswick NJ 08903 USA Department of Urology Dankook University College of Medicine Cheonan 31116 South Korea.

The aim of this study is to identify optimal patients for adjuvant radiation therapy （ART） in pT3 prostate cancer. The role of ART for patients with adverse pathologic features after radical prostatectomy （RP） has been demonstrated, but over- or under-treatment remains a significant concern. Two-hundred and five patients with pT3NOMO who underwent robot-assisted RP without ART were analyzed. Multivariate Cox proportional regression analyses were used to identify predictors of biochemical recurrence （BCR） and clinical progression （CP）. The estimated 5-year BCR-free survival （BCRFS） and CP-free survival （CPFS） were 52.8% and 85.6%, respectively. Preoperative prostate-specifc antigen （PSA）：〉10 ng m1-1 （hazard ratio [HR]： 3.288-6.027; P = 0.003）, pathologic Gleason score （pGS）：〉8 （HR： 4.146; P = 0.014）, and lymphovascular invasion （LVI）（HR： 2.167; P = 0.026） were associated with BCR. Based on these factors, a risk stratification tool was developed. Patients with no risk factors （PSA 〈10 ng m1-1, pGS 6, and absent LVI） showed excellent BCRFS and CPFS at 5 years （91.9% and 100.0%, respectively）, but those with two or more risk factors （PSA ：〉10 ng ml-1, pGS ≥8, or present LVI） had poor BCRFS and CPFS （12.1% and 54.6%, respectively）. In addition, the multivariate analysis revealed that pathologic stage pT3b （HR： 5.393; P = 0.025） was the only predictor of CP. Our study demonstrated the heterogeneity of oncologic outcomes in patients with pT3 prostate cancer. The proposed risk stratification can be used to identify patients who are at risk for disease progression and may aid in identifying the best patients for ART.

关键词： prostatectomy prostate-specific antigen recurrence survival

Incremental expectation maximization principal component analysis for missing value imputation for coevolving EEG data

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Journal of Zhejiang University-Science C(Computers and Electronics) 2011年第8期12卷 687-697页

作者： Sun hee KIM Hyung jeong YANG Kam Swee NG Department of Computer Science Chonnam National University

Missing values occur in bio-signal processing for various reasons,including technical problems or biological *** missing values are then either simply excluded or substituted with estimated values for further *** the missing signal values are estimated for electroencephalography (EEG) signals,an example where electrical signals arrive quickly and successively,rapid processing of high-speed data is required for immediate decision *** this study,we propose an incremental expectation maximization principal component analysis (iEMPCA) method that automatically estimates missing values from multivariable EEG time series data without requiring a whole and complete data *** proposed method solves the problem of a biased model,which inevitably results from simply removing incomplete data rather than estimating them,and thus reduces the loss of information by incorporating missing values in real *** using an incremental approach,the proposed method alsominimizes memory usage and processing time of continuously arriving *** results show that the proposed method assigns more accurate missing values than previous methods.

关键词： Electroencephalography (EEG) Missing value imputation Hidden pattern discovery Expectation maximization Principal component analysis