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Electron Paramagnetic Resonance of Gd3＋ in Cs 2Na Y0.75 H o0.25CI6

材料科学与工程（中英文B版） 2011年第3期1卷 352-357页

作者： Josefina Maldonado Jorge Barreto Jose Luis Boldu hector del castillo Eduardo Mufioz Picone Instituto de Fisica Universidad Nacional Autonoma de Mexico Circuito de la Investigacion Cientifica Ciudad Universitaria D.F. 04510 Mexico

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The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine

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Genes & Diseases 2019年第3期6卷 201-223页

作者： Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy hector castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid The University of Chicago Pritzker School of Medicine ChicagoIL 60637USA Laboratory of Craniofacial Biology and Development Section of Plastic and Reconstructive SurgeryDepartment of SurgeryThe University of Chicago MedicineChicagoIL 60637USA Molecular Oncology Laboratory Department of Orthopaedic Surgery and Rehabilitation MedicineThe University of Chicago Medical CenterChicagoIL 60637USA Rosalind Franklin University Chicago Medical SchoolNorth ChicagoIL 60064USA SIR Program Illinois Math and Science Academy(IMSA)AuroraIL 60506USA Department of Biomedical Engineering Northwestern UniversityEvanstonIL60208USA The Department of Surgery Feinberg School of MedicineNorthwestern UniversityChicagoIL60616USA

Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological *** roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ *** of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP *** it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other *** effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of ***,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and *** review aims to summarize our current understanding of BMP9 across biology and the body.

关键词： Adipogenesis Bone morphogenetic proteins(BMPs) BMP9/GDF2 Mesenchymal stem cells(MSCs) Metabolism Osteogenesis Regenerative medicine Tumorigenesis

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Locomotor recovery after spinal cord injury:intimate dependence between axonal regeneration and re-connection

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Neural Regeneration Research 2022年第3期17卷 553-554页

作者： hector Ramiro Quintá Consejo Nacional de Investigaciones Científicas y Técnicas CONICET Laboratorio de Medicina Experimental“Dr.Jorge E.Toblli” Hospital AlemánBuenos AiresArgentina

Traumatic spinal cord injuries(SCI) are characterized by damage in the integrity of the spinal cord,which results in either temporary or permanent alterations in the locomotor,sensory and/or autonomic functions(Yezierski,2009).The traumatic event leads to impairments in voluntary control of movement below the injury by affecting the connection between the brain and the neurons localized in the spinal cord.

关键词： injuries alterations damage

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Detection of presumed genes encoding beta-lactamases by sequence based screening of metagenomes derived from Antarctic microbial mats

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Frontiers of Environmental Science & Engineering 2019年第3期13卷 173-184页

作者： Gaston Azziz Matias Gimenez hector Romero Patricia M. Valdespino-castillo Luisa I. Falcon Lucas A. M. Ruberto Walter P. Mac Cormack Silvia Batista Molecular Microbiology Unit Clemente Estable Biological Research Insitute Montevideo 11600 Uruguay Microbiology Laboratory Faculty of Agronomy UdelaR Montevideo 12900 Uruguay Genome Organization and Evolution Laboratory Ecology and Evolution Department Faculty of Sciences UdelaR Montevideo 11400 Uruguay Molecular Biophysics and Integrated Bioimaging BSISB Imaging Program Lawrence Berkeley National Laboratory Berkeley CA 94720 USA Bacteial Ecology Laboratory Ecology Institute National Autonomous University of Mexico CDMX 04510 Mexico UN AM Yucatan Technology and Science Park Merida 97302 Mexico Argentine Antarctic Institute Buenos Aires 1650 Argentina Biotechnology Unit Faculty of Pharmacy and Biochemistry Nanobiotec Institute UBA-CONICET Buenos Aires 1113 Argentina

Analysis of environmental samples for bacterial antibiotic resistance genes may have different objectives and analysis strategies. In some cases, the purpose was to study diversity and evolution of genes that could be grouped within a mechanism of antibiotic resistance. Different protocols have been designed for detection and confirmation that a functional gene was found. In this study, we present a sequence-based screening of candidate genes encoding beta-lactamases in 14 metagenomes of Antarctic microbial mats. The samples were obtained from different sites, representing diverse biogeographic regions of maritime and continental Antarctica. A protocol was designed based on generation of Hidden Markov Models from the four beta-lactamase classes by Ambler classification, using sequences from the Comprehensive Antibiotic Resistance Database (CARD). The models were used as queries for metagenome analysis and recovered contigs were subsequently annotated using RAST. According to our analysis, 14 metagenomes analyzed contain A, B and C beta-lactamase genes. Class D genes, however, were identified in 11 metagenomes. The most abundant was class C (46.8%), followed by classes B (35.5%), A (14.2%) and D (3.5%). A considerable number of sequences formed clusters which included, in some cases, contigs from different metagenomes. These assemblies are clearly separated from reference clusters, previously identified using CARD beta-lactamase sequences. While bacterial antibiotic resistance is a major challenge of public health worldwide, our results suggest that environmental diversity of beta-lactamase genes is higher than that currently reported, although this should be complemented with gene function analysis.

关键词： Beta-lactamases Antibiotic resistance coding genes Metagenomes Antarctic microbial mats

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Beam design for voice coil motors used for energy harvesting purpose with low frequency vibrations:A finite element analysis

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International Journal of Modeling, Simulation, and Scientific Computing 2016年第3期7卷 1-17页

作者： hector A.Tinoco Department of Mechanics and Production Universidad Autonoma de Manizales(UAM)Grupo de Diseno Mecanico y Desarrollo Industrial Antigua Estaci´on del Ferrocarril Edificio Sacatin C.P.170001 Manizales-Caldas Colombia

In this study,a numerical approach is established to design a beam coupled to a Voice Coil Motor(VCM)with the aim to maximize the displacement in the inductive transducer.A finite element model is developed to simulate a VCM with different beams applying a harmonic *** VCM is extracted from a recycled hard disk drive(HDD)and a parametric modal analysis is performed to identify the material parameters of the HDD and the *** parameters are obtained comparing the real vibration modes and natural frequencies(VCM-beam)with those determined from the finite element model.A numerical-experimental case study is carried out to demonstrate that if a beam is designed for a specific low frequency vibration between 0 and 10 Hz,the displacements are maximized in the *** this purpose,real acceleration measurements taken from three individuals are used to provide the vibration signals in the numerical model.A beam is designed for one of the individuals using the natural frequency values determined from the measured *** show that the displacements are maximized in the model which coincides with the natural frequency of the chosen *** main purpose of this research is to establish a design tool for energy harvesting purposes with VCM based on low frequency vibration sources as for example gait motions.

关键词： Hard disk drive HDD energy harvesting finite element analysis Wiimote voice coil motor VCM modal analysis

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Inference for a truncated positive normal distribution

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Applied Mathematics(A Journal of Chinese Universities) 2018年第2期33卷 163-176页

作者： hector J.Gomez Neveka M.Olmos hector Varela Heleno Bolfarine Departamento de Ciencias Matematicas y Ffsicas Facultad de IngenierlaUniversidad Catolica de TemucoTemucoChile Departamento de Matematicas Facultad de Ciencias BasicasUniversidad de AntofagastaAntofagastaChile Departamento de Estatfstica IMEUniversidade de Sao PauloSao PauloBrazil

The main object of this paper is to study an extension of the half normal distribution defined by adding a positive truncation to it. The new model is more flexible than the half-normal distribution and contains the half normal distribution as a special case. Properties of this distribution, such as moments, hazard function and entropy are studied and parameters estimation is dealt with by using inoinents and inaxiinuin likelihood. A real data application indicates good fit performance of the new model when compared to other competitors in litera- tures.

关键词： half-normal distribution maximum likelihood truncation

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Molecular aspects of mammalian fertilization

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Asian Journal of Andrology 2001年第4期3卷 243-249页

作者： hector Serrano Dolores Garcia-Suarez Dept. Health Sciences Dept. Biology Universidad Autonoma Metropoliana-Iztapalapa Ave. Michoacan and Purisima Mexico City DF 09340 Mexico

Mammalian fertilization is a highly regulated process, much of which are not clearly understood. Here we presentsome information in order to elaborate a working hypothesis for this process, beginning with the sperm modifications inthe epidydimis up to sperm and egg plasmalemma interaction and fusion. We also discuss the still poorly understood ca-pacitation process, the phenomenon of sperm chemo-attraction that brings the capacitated sperm to interact with theoocyte vestments and certain aspects of the acrosome reaction. (Asian J Androl 2001 Dec; 3 : 243 - 249)

关键词： fertilization sperm maturation sperm capacitation sperm-ovum interactions membrane fusion

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The implementation and data analysis of an interferometer for intense short pulse laser experiments

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High Power Laser Science and Engineering 2016年第3期4卷 60-66页

作者： Jaebum Park hector A.Baldis Hui Chen Lawrence Livermore National Laboratory University of California

We present an interferometry setup and the detailed fringe analysis method for intense short pulse(SP) laser *** interferometry scheme was refined through multiple campaigns to investigate the effects of pre-plasmas on energetic electrons at the Jupiter Laser Facility at Lawrence Livermore National Laboratory. The interferometer used a frequency doubled(λ=0.527 μm) 0.5 ps long optical probe beam to measure the pre-plasma density, an invaluable parameter to better understand how varying pre-plasma conditions affect the characteristics of the energetic electrons. The hardware of the diagnostic, data analysis and example data are presented. The diagnostic setup and the analysis procedure can be employed for any other SP laser experiments and interferograms, respectively.

关键词： Mach-Zehnder interferometer optical interferometry picosecond probe plasma density short pulse laser

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Radicals and Kothe’s Conjecture for Skew PBW Extensions

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Communications in Mathematics and Statistics 2021年第2期9卷 119-138页

作者： Armando Reyes hector Suarez Departamento de Matematicas Universidad Nacional de ColombiaSede BogotaColombia Escuela de Matemáticas y Estadística Universidad Pedagogica y Tecnológica de ColombiaSede TunjaColombia

The aim of this paper is to investigate different radicals(Wedderburn radical,lower nil radical,Levitzky radical,upper nil radical,the set of all nilpotent elements,the sum of all nil left ideals)of the noncommutative rings known as skew Poincare–Birkhoff–Witt *** characterize minimal prime ideals of these rings and prove that the Kothe’s conjecture holds for these ***,we establish the transfer of several ring-theoretical properties(reduced,symmetric,reversible,2-primal)from the coefficients ring of a skew PBW extension to the extension itself.

关键词： Armendariz rings Kothe’s conjecture Skew PBW extensions

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A study of process-induced grain structures during steady state and non-steady state electron-beam welding of a titanium alloy

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Journal of Materials Science & Technology 2022年第18期113卷 117-127页

作者： Yu Lu Richard Turner Jeffery Brooks hector Basoalto School of Metallurgy and Materials University of BirminghamBirminghamB152TTUnited Kingdom Department of Materials Science and Engineering The University of SheffieldMappin StreetSheffieldS13JDUnited Kingdom

A detailed microstructural characterisation of the emerging weld-line grain structure,for bead-upon-plate welds in Ti-6Al-4V(Ti64)of differing plate thickness,was *** microstructure studied was formed during both steady state and non-steady state sections within the weld path,with the non-steady state portion being taken from the end of the plate as the weld bead and heat source overhang the edge of the *** allows for the effects of welding process conditions on the microstructural evolution to be *** weld pool geometry and 3D tomography of the weld-induced defects have been *** characterisation of microstructure and texture for different welding parameters and for steady and non-steady states have been used to identify physical parameters for the microstructure predictions that are difficult to obtain *** different states significantly affect the weld crown shape and formation,weld toe,weld bead depth and ***,the heat affected zone(HAZ)re-mains *** the microstructural evolution,both the steady and non-steady states have similar microstructure and *** defects were observed in the steady state section of welds,but sub-surface spherical pores have been observed in the non-steady state section of a *** element modelling to simulate the thermal-metallurgical-mechanical fields within the steady and non-steady state sections of the welds was considered,and the cooling rates predicted within steady state and non-steady sections were interrogated to improve the theoretical understanding of the microstructure and defect formation differences in these Ti64 EB weld regions.

关键词： Electron-beam fusion welding Processing Microstructure Ti-6Al-4V

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