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Genetic Variability and Phenotypic Correlations Study among Grain Quality Traits and Mineral Elements Concentrations in Colored and Non-Colored Rice (Oryza sativa L.)

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1733-1748页

作者： Adel A.Rezk Mohamed M.El-Malky heba I.Mohamed Hossam S.El-Beltagi Agricultural Biotechnology Department College of Agricultural and Food ScienceKing Faisal UniversityAl-Ahsa31982Saudi Arabia Plant Pathology Research Institute Agriculture Research CenterGiza12619Egypt Rice Research and Training Center Field Crop Research InstituteAgriculture Research Center33717Egypt Biological and Geological Sciences Department Faculty of EducationAin Shams UniversityCairo11511Egypt Biochemistry Department Faculty of AgricultureCairo UniversityGiza12613Egypt

Twenty-four rice genotypes were examined to assess genetic variability,heritability,and correlations for seven-grain quality traits,eight nutritional elements,and *** revealed signiﬁcant differences for the quality traits *** every trait under study,the phenotypic coefﬁcient of variation was higher than the correspon-dence genotypic coefﬁcient of *** in a broad sense varied from 29.75%for grain length to 98.31%for the elongation *** percentage recovery had a highly signiﬁcant positive correlation with milling and head rice ***,milling percentage had a highly positive correlation with head rice *** amylose percentage,all the genotypes belonged to low amylose except the Hassawi-1 variety,which had intermediate amylose *** nutrition contents of magnesium(Mg),sodium(Na),potas-sium(K),calcium(Ca),copper(Cu),manganese(Mn),zinc(Zn),iron(Fe),or protein percentage gave different variations for 24 rice genotypes under all the nutritional *** the 24 genotypes,ten rice genotypes–HighNutrient-1,HighNutrient-2,HighNutrient-9,HighNutrient-8,HighNutrient-3,Hassawi-2,HighNutrient-7,HighNutrient-6,Hassawi-1,and HighNutrient-4–had the highest heist value for all nutritional and protein con-tents,and could be used as a donor to improving new *** was a positive and signiﬁcant correlation between magnesium Mg,K,Zn and ***,K had a positive correlation with zinc Zn,Fe,and protein *** analysis was divided into two groups:theﬁrst group included all genotypes rich in nutri-ents,while the remaining genotypes with low nutritional content were included in the second group.

关键词： Amylose cluster analysis genotypes grain quality mineral nutrition rice

Impact of auditory stimulation nursing protocol on auditory response in cerebrovascular stroke patients

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Journal of Integrative Nursing 2024年第2期6卷 111-116页

作者： Mohammed ElSayed ZAKY Hanan Ahmed AL SEBAEE Nagat El Morsy IBRAHIEM heba Ahmed MOHAMMED Mohammad Edrees MOHAMMAD Department of Medical Surgical Nursing Faculty of NursingCairo UniversityCairoEgypt Department of Neurology Faculty of MedicineCairo UniversityCairoEgypt

Objectives:The objective of the study was to explore the impact of auditory stimulation protocol on auditory response in cerebrovascular stroke(CVS)*** and Methods:A pre-posttest nonequivalent control group quasi-experimental study was conducted at Al Mainal Hospital at Al Kars Einy Hospital,Cairo University,among 60 CVS patients,and the sample was randomly assigned through a coin to allocate subjects to study or control group(30 for each group).Auditory stimulation techniques were applied three times per week for the study group for two consecutive *** in the control group received only routine hospital care during the study *** Glasgow Coma Scale(GCS)score for assessing the neurological function and level of arousal and the auditory subscale score of Western Neuro Sensory Stimulation Profile(WNSSP)for assessing auditory response were recorded and compared between the two groups before and after the ***:There were statistically significant differences between the study group and the control group regarding third reading of GCS score(11.5±0.3 vs.10.6±0.9,t=4.676,P=0.000).The scores of all auditory subscales of WNSSP in the study groups increased after implementing the auditory stimulation protocol(P<0.05).Conclusion:Utilizing the auditory stimulation protocol by nurse proves to be an effective method for enhancing hearing responses in individuals with CVS.

关键词： Auditory stimulation techniques hearing response nursing management stroke

Dysfunction of the adhesion G protein-coupled receptor latrophilin 1(ADGRL1/LPHN1)increases the risk of obesity

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Signal Transduction and Targeted Therapy 2024年第5期9卷 2298-2311页

作者： heba ZabriTorsten Schöneberg AndréNguyen Dietzsch Hadi Al-Hasani Joachim Altschmied Katharina Bottermann Jana Brendler Judith Haendeler Susanne Horn Isabell Kaczmarek Antje Körner Kerstin Krause Kathrin Landgraf Diana Le Duc Laura Lehmann Stefan Lehr Stephanie Pick Albert Ricken Rene Schnorr Angela Schulz Martina Strnadová Akhil Velluva heba Zabri Torsten Schöneberg Doreen Thor Simone Prömel Rudolf Schönheimer Institute of Biochemistry Medical FacultyLeipzig UniversityLeipzigGermany Institute for Clinical Biochemistry and Pathobiochemistry Medical FacultyGerman Diabetes CenterLeibniz Center for Diabetes Research at Heinrich Heine University DüsseldorfDüsseldorfGermany German Center for Diabetes Research(DZD e.V.) Munich-NeuherbergGermany Cardiovascular Degeneration Clinical Chemistry and Laboratory DiagnosticsMedical FacultyUniversity Hospital and Heinrich Heine University DüsseldorfDüsseldorfGermany Cardiovascular Research Institute(CARID) Medical FacultyUniversity Hospital and Heinrich Heine University DüsseldorfDüsseldorfGermany Institute of Pharmacology Medical FacultyUniversity Hospital and Heinrich Heine University DüsseldorfDüsseldorfGermany Institute of Anatomy Medical FacultyLeipzig UniversityLeipzigGermany Center for Pediatric Research Hospital for Children and AdolescentsMedical FacultyLeipzig UniversityLeipzigGermany Helmholtz Institute for Metabolic Obesity and Vascular Research(HI-MAG)of the Helmholtz Zentrum München at the University of Leipzig and University Hospital LeipzigLeipzigGermany Department of Endocrinology NephrologyRheumatologyLeipzig University Medical CenterLeipzigGermany Institute of Human Genetics Leipzig University Medical CenterLeipzigGermany Institute of Cell Biology Department of BiologyHeinrich Heine University DüsseldorfDüsseldorfGermany School of Medicine University of Global Health EquityKigaliRwanda

Obesity is one of the diseases with severe health consequences and rapidly increasing worldwide *** the complex network of food intake and energy balance regulation is an essential prerequisite for pharmacological intervention with obesity.G protein-coupled receptors(GPCRs)are among the main modulators of metabolism and energy ***,for instance,regulate appetite and satiety in certain hypothalamic neurons,as well as glucose and lipid metabolism and hormone secretion from *** in some GPCRs,such as the melanocortin receptor type 4(MC4R),have been associated with early-onset ***,we identified the adhesion GPCR latrophilin 1(ADGRL1/LPHN1)as a member of the regulating network governing food intake and the maintenance of energy *** of the highly conserved receptor in mice results in increased food consumption and severe obesity,accompanied by dysregulation of glucose ***,we identified a partially inactivating mutation in human ADGRL1/LPHN1 in a patient suffering from ***,we propose that LPHN1 dysfunction is a risk factor for obesity development.

关键词： obesity metabolism intake

Optimization of Cooperative RelayingMolecular Communications for Nanomedical Applications

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1259-1275页

作者： Eman S.Attia Ashraf A.M.khalaf Fathi E.Abd El-Samie Saied M.Abd El-atty Konstantinos A.Lizos Osama Alfarraj heba M.El-Hoseny Department of Electrical Engineering Faculty of EngineeringMinia UniversityMinia61111Egypt Department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt Department of Informatics Faculty of Mathematics and Natural SciencesUniversity of Oslo(UiO)OsloNorway Computer Science Department Community CollegeKing Saud UniversityRiyadh11437Saudi Arabia Department of Computer science The Higher Future Institute for Specialized Technological StudiesEl ShoroukEgypt

Recently,nano-systems based on molecular communications via diffusion(MCvD)have been implemented in a variety of nanomedical applications,most notably in targeted drug delivery system(TDDS)***,because the MCvD is unreliable and there exists molecular noise and inter symbol interference(ISI),cooperative nano-relays can acquire the reliability for drug delivery to targeted diseased cells,especially if the separation distance between the nano transmitter and nano receiver is *** this work,we propose an approach for optimizing the performance of the nano system using cooperative molecular communications with a nano relay scheme,while accounting for blood flow effects in terms of drift *** fractions of the molecular drug that should be allocated to the nano transmitter and nano relay positioning are computed using a collaborative optimization problem solved by theModified Central Force Optimization(MCFO)*** the previous work,the probability of bit error is expressed in a closed-form *** is used as an objective function to determine the optimal velocity of the drug molecules and the detection threshold at the nano *** simulation results show that the probability of bit error can be dramatically reduced by optimizing the drift velocity,detection threshold,location of the nano-relay in the proposed nano system,and molecular drug budget.

关键词： Nanomedical system molecular communication cooperative relay optimization

Adherence to Advisory Committee on Immunization Practices in diabetes mellitus patients in Saudi Arabia:A multicenter retrospective study

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World Journal of Diabetes 2024年第3期15卷 440-454页

作者： Saleh Fahad Alqifari Aya K Esmail Dalal M Alarifi Ghalya Y Alsuliman Maram M Alhati May R Mutlaq Mohammed Aldhaeefi Shaden A Alshuaibi Palanisamy Amirthalingam Abrar Abdallah Afaf S Wasel heba R Hamad Shoroq Alamin Tasneem H Atia Tariq Alqahtani Department of Pharmacy Practice University of TabukTabuk 71491Saudi Arabia Department of Clinical Sciences Sulaiman Alrajhi UniversityQassim 52726Saudi Arabia Department of Family Medicine International Medical CenterJeddah 23214Saudi Arabia Clinical and Administrative Pharmacy Sciences College of PharmacyHoward UniversityWashingtonDC 20059United States Department of Pharmacology King Saud Bin Abdulaziz University for Health SciencesKing Abdullah International Medical Research CenterRiyadh 11481Saudi Arabia

BACKGROUND Patients with diabetes mellitus(DM)are predisposed to an increased risk of infection signifying the importance of vaccination to protect against its potentially severe *** Centers for Disease Control and Prevention/Advisory Committee on Immunization Practices(CDC/ACIP)issued immunization recommendations to protect this patient *** To assess the adherence of patients with DM to the CDC/ACIP immunization recommendations in Saudi Arabia and to identify the factors associated with the vaccine adherence *** An observational retrospective study conducted in 2023 was used to collect data on the vaccination records from 13 diabetes care centers in Saudi Arabia with 1000 eligible patients in phase I with data collected through chart review and 709 patients in phase II through online *** Among participants,10.01%(n=71)had never received any vaccine,while 85.89%(n=609)received at least one dose of the coronavirus disease 2019(COVID-19)vaccine,and 34.83%(n=247)had received the annual influenza *** 2.96%(n=21),2.11%(n=15),and 1.12%(n=8)received herpes zoster,tetanus,diphtheria,and pertussis(Tdap),and human papillomavirus(HPV)vaccines,*** patients with DM in Saudi Arabia,the rate of vaccination for annual influenza and COVID-19 vaccines was higher compared to other vaccinations such as herpes zoster,Tdap,pneumococcal,and *** such as vaccine recommendations provided by family physicians or specialists,site of care,income level,DM-related hospitalization history,residency site,hemoglobin A1c(HbA1c)level,and health sector type can significantly influence the vaccination rate in patients with *** non-vaccinated patients with DM,the most reported barriers were lack of knowledge and fear of side *** signifies the need for large-scale research in this area to identify additional factors that might facilitate adherence to CDC/ACIP vaccine recommendations in patients with *** In S

关键词： Diabetes mellitus Vaccine recommendation COVID-19 vaccine Influenza vaccine Pneumococcal vaccine Immunization Retrospective study

Chaotic Elephant Herd Optimization with Machine Learning for Arabic Hate Speech Detection

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Intelligent Automation & Soft Computing 2024年第3期39卷 567-583页

作者： Badriyya B.Al-onazi Jaber S.Alzahrani Najm Alotaibi Hussain Alshahrani Mohamed Ahmed Elfaki Radwa Marzouk heba Mohsen Abdelwahed Motwakel Department of Language Preparation Arabic Language Teaching InstitutePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Industrial Engineering College of Engineering at AlqunfudahUmm Al-Qura UniversityMecca24382Saudi Arabia Prince Saud AlFaisal Institute for Diplomatic Studies Riyadh12735Saudi Arabia Department of Computer Science College of Computing and Information TechnologyShaqra UniversityShaqra11911Saudi Arabia Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Computer Science Faculty of Computers and Information TechnologyFuture University in Egypt New CairoNew Cairo11835Egypt Department of Computer and Self Development Preparatory Year DeanshipAl-Kharj16278Saudi Arabia

In recent years,the usage of social networking sites has considerably increased in the Arab *** has empowered individuals to express their opinions,especially in ***,various organizations that operate in the Arab countries have embraced social media in their day-to-day business activities at different *** is attributed to business owners’understanding of social media’s importance for business ***,the Arabic morphology is too complicated to understand due to the availability of nearly 10,000 roots and more than 900 patterns that act as the basis for verbs and *** speech over online social networking sites turns out to be a worldwide issue that reduces the cohesion of civil *** this background,the current study develops a Chaotic Elephant Herd Optimization with Machine Learning for Hate Speech Detection(CEHOML-HSD)model in the context of the Arabic *** presented CEHOML-HSD model majorly concentrates on identifying and categorising the Arabic text into hate speech and *** attain this,the CEHOML-HSD model follows different sub-processes as discussed *** the initial stage,the CEHOML-HSD model undergoes data pre-processing with the help of the TF-IDF ***,the Support Vector Machine(SVM)model is utilized to detect and classify the hate speech texts made in the Arabic ***,the CEHO approach is employed for fine-tuning the parameters involved in *** CEHO approach is developed by combining the chaotic functions with the classical EHO *** design of the CEHO algorithm for parameter tuning shows the novelty of the work.A widespread experimental analysis was executed to validate the enhanced performance of the proposed CEHOML-HSD *** comparative study outcomes established the supremacy of the proposed CEHOML-HSD model over other approaches.

关键词： Arabic language machine learning elephant herd optimization TF-IDF vectorizer hate speech detection

Repurposing verapamil for prevention of cognitive decline in sporadic Alzheimer's disease

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Neural Regeneration Research 2022年第5期17卷 1018-1019页

作者： heba A.Ahmed Tauheed Ishrat Department of Anatomy and Neurobiology University of Tennessee Health Science CenterMemphisTNUSA Pharmaceutical Sciences Neuroscience InstituteUniversity of Tennessee Health Science CenterMemphisTNUSA

Dementia is currently the only leading cause of death that is still on the rise,with its overall costs already surpassing those of cancer and heart disease combined,it has developed into a worldwide *** response to its serious and far-reaching effects,the US government has established the"National Alzheimer's Project Act"(Public Law 111-375).

关键词： Alzheimer prevention death verapamil

An Efficient Ensemble Model for Various Scale Medical Data

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Computers, Materials & Continua 2022年第10期73卷 1283-1305页

作者： heba A.Elzeheiry Sherief Barakat Amira Rezk Information System Department Faculty of Computers and InformationMansoura UniversityMansoura35516Egypt

Electronic Health Records(EHRs)are the digital form of patients’medical reports or *** facilitate advanced analytics and aid in better decision-making for clinical *** data are very complicated and using one classification algorithm to reach good results is *** this reason,we use a combination of classification techniques to reach an efficient and accurate classification *** model combination is called the Ensemble *** need to predict new medical data with a high accuracy value in a small processing *** propose a new ensemble model MDRL which is efficient with different *** MDRL gives the highest accuracy *** saves the processing time instead of processing four different algorithms sequentially;it executes the four algorithms in *** implement five different algorithms on five variant datasets which are Heart Disease,Health General,Diabetes,Heart Attack,and Covid-19 *** four algorithms are Random Forest(RF),Decision Tree(DT),Logistic Regression(LR),and Multi-layer Perceptron(MLP).In addition to MDRL(our proposed ensemble model)which includes MLP,DT,RF,and LR *** our experiments,we conclude that our ensemble model has the best accuracy value for most *** reach that the combination of the Correlation Feature Selection(CFS)algorithm and our ensemble model is the best for giving the highest accuracy *** accuracy values for our ensemble model based on CFS are 98.86,97.96,100,99.33,and 99.37 for heart disease,health general,Covid-19,heart attack,and diabetes datasets respectively.

关键词： Electronic health records(EHRs) Random forest(RF) Decision tree(DT) linear model(LR) Multi-layer Perceptron(MLP) MDRL correlation feature selection(CFS)

Optimized Deep Learning Approach for Efficient Diabetic Retinopathy Classification Combining VGG16-CNN

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Computers, Materials & Continua 2023年第11期77卷 1855-1872页

作者： heba M.El-Hoseny heba F.Elsepae Wael A.Mohamed Ayman S.Selmy Department of Computer Science the Higher Future Institute for Specialized Technological StudiesObour11828Egypt Department of Electrical Engineering Benha Faculty of EngineeringBenha UniversityBenha13511Egypt

Diabetic retinopathy is a critical eye condition that,if not treated,can lead to vision *** methods of diagnosing and treating the disease are time-consuming and ***,machine learning and deep transfer learning(DTL)techniques have shown promise in medical applications,including detecting,classifying,and segmenting diabetic *** advanced techniques offer higher accuracy and *** Diagnosis(CAD)is crucial in speeding up classification and providing accurate disease ***,these technological advancements hold great potential for improving the management of diabetic *** study’s objective was to differentiate between different classes of diabetes and verify the model’s capability to distinguish between these *** robustness of the model was evaluated using other metrics such as accuracy(ACC),precision(PRE),recall(REC),and area under the curve(AUC).In this particular study,the researchers utilized data cleansing techniques,transfer learning(TL),and convolutional neural network(CNN)methods to effectively identify and categorize the various diseases associated with diabetic retinopathy(DR).They employed the VGG-16CNN model,incorporating intelligent parameters that enhanced its *** outcomes surpassed the results obtained by the auto enhancement(AE)filter,which had an ACC of over 98%.The manuscript provides visual aids such as graphs,tables,and techniques and frameworks to enhance *** study highlights the significance of optimized deep TL in improving the metrics of the classification of the four separate classes of *** manuscript emphasizes the importance of using the VGG16CNN classification technique in this context.

关键词： No diabetic retinopathy(NDR) convolution layers(CNV layers) transfer learning data cleansing convolutional neural networks a visual geometry group(VGG16)