检索结果-南通市图书馆

Saikosaponin D suppresses enterovirus A71 infection by inhibiting autophagy

Signal Transduction and Targeted Therapy 2019年第1期4卷 602-613页

作者： Chang Li Lihong Huang Wei Sun Ying Chen Ming-Liang He Jianbo Yue heather ballard School of Biomedical Sciences University of Hong KongHong KongChina City University of Hong Kong ShenZhen Research Institute ShenZhenChina Department of Biomedical Sciences City University of Hong KongHong KongChina

The dysregulation of autophagy,an evolutionarily conserved lysosomal degradation process,has been implicated in a wide variety of human diseases,and thus,small chemicals that modulate autophagy have therapeutic ***,we assessed the ability of active components isolated from Bupleurum falcatum,a popular Chinese herb,to modulate *** found that saikosaponin D(SsD)and A(SsA)but not C(SsC)potently and reversibly inhibited the fusion of autophagosomes and lysosomes,resulting in the accumulation of autophagosomes,an increased lysosomal pH,and TFEB nuclear ***5A knockdown or the expression of a dominant-negative RAB5 mutant significantly reduced the ability of SsD or SsA to block *** A71(EV-A71),the cause of hand-foot-mouth disease,has been shown to induce *** found that SsD potently inhibited EV-A71 RNA replication and subsequent viral protein synthesis,thereby preventing EV-A71-induced cell ***5 knockdown inhibited EV-A71 viral protein synthesis,whereas autophagy induction by rapamycin promoted *** together,our data indicate that SsD and SsA are potent late-stage autophagy inhibitors that can be used to prevent EV-A71 infection.

关键词： inhibited inhibiting assessed

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Lead Phytoremediation in Contaminated Soils Using Ornamental Landscape Plants

引用

Journal of Geoscience and Environment Protection 2021年第5期9卷 152-164页

作者： Danna Thompson Edward Bush heather Kirk-ballard Joseph’s Academy Baton Rouge LA USA LSU AgCenter Baton Rouge LA USA

Lead (Pb) in the urban environment can have a negative effect on human health, especially children’s health. Reducing elevated Pb exposure in the home landscape is essential. The purpose of this study was to determine which ornamental groundcover landscape plants uptake Pb from contaminated soil. Plants for both shade and sun were selected. Plants for shade [Brake fern (Pteris vittata), Asian Jasmine (Trachelospermum asiaticum), “Big Blue” Liriope (Liriope muscari), and St. Augustinegrass (Stenotaphrum secundatum)] and sun [Variegated Liriope (Liriope muscari “Variegata”), Asian Jasmine (Trachelospermum asiaticum), Asparagus Fern (Asparagus setaceus), and Bermudagrass (Cynodon dactylon)] adapted landscape groundcover plants successfully assimilated Pb grown in soil containing 250 ppm and 500 ppm Pb concentrations. Additionally, soil movement at both 25 mph and 50 mph wind speed was significantly different, with increased soil movement at 50 mph. Therefore, it was determined that landscape plants adapted to both sun and shade can help remove Pb from contaminated soils and stabilize soil particles reducing the movement of soil and be aesthetically pleasing.

关键词： Soil Heavy Metals Remediation Soil Health Urban Horticulture Phytoextraction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evaluation of Barriers to Prevent Lead Contamination of Produce Grown in Urban Gardens

引用

Journal of Environmental Protection 2020年第12期11卷 1064-1072页

作者： Celine Richard Kathryn Fontenot Edward Bush heather Kirk-ballard M. Taylor Bryant School of Plant Environmental & Soil Sciences Louisiana State University Agricultural Center Baton Rouge USA

High lead (Pb) contamination of soils is a threat to human health. Indirect ingestion occurs within the food chain through activities such as growing vegetables with an ability to accumulate lead in edible tissues. Many university extension systems recommend growing vegetables in raised beds to avoid lead contamination. However, there is limited scientific evidence of the efficacy of raised beds in reducing lead uptake in vegetable crops. To address the soil-lead exposure pathway from garden to consumption, this study supplements gaps in the literature pertaining to raised-bed garden practices by evaluating lining materials. Simulated raised beds were constructed to evaluate barriers (neoprene rubber sheeting, landscape fabric and a no barrier control) placed between contaminated (500 ppm) and uncontaminated garden media. The resulting data suggests that neoprene rubber sheeting is not an effective barrier to prevent lead uptake in vegetable crops. In fact, the neoprene barrier contained elevated amounts of lead contributing to higher levels of lead (p ≤ 0.05) within the plant tissue as compared to a no barrier treatment.

关键词： Raised Bed Chinese Cabbage Heavy Metal Soilless Media

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of Irrigation and Drought on Growth and Essential Oil Production in O. vulgare and R. officinalis

引用

American Journal of Plant Sciences 2022年第5期13卷 659-667页

作者： David C. Baudoin Edward Bush Ted Gauthier Amy B. Hernandez heather Kirk-ballard LSU AgCenter School of Plant Environmental & Soil Sciences Miller Hall USA

The essential oil industry has led a rapidly growing market in American herbal medicine. The global essential oil industry was valued at an estimated 18.6 billion USD in 2020 and is expected to have a compound annual growth rate of 7.6% from 2020 to 2027. “Essential oil” is a broad term used to describe volatile organic compounds (VOCs) that are often associated with a plant’s essence or aroma. These molecules are commonly extracted from a variety of different plant structures by steam distillation and cold pressing. Essential oils function as a defense against insects, bacteria, fungi, and other stressors, such as drought and cold. The most industrially important of this class of compounds are monoterpenes, steam-volatile constituents which are the most abundant terpenes throughout plants. Essential oils may include monoterpenes (two isoprene units), sesquiterpenes (three isoprene units), ketones, and phenolics. Phenolics include flavonoids, anthocyanins, and tannins.

关键词： Water Relations Essential Oil Extraction Terpenes Plant Environmental Stress Mass Spectroscopy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：