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Prognostic value of hemodynamic indices in patients with sepsis after fluid resuscitation

World Journal of Clinical Cases 2021年第13期9卷 3008-3013页

作者： he-ping xu Xiao-An Zhuo Jin-Jian Yao Duo-Yi Wu Xiang Wang ping he Yan-Hong Ouyang Department of Emergency Medicine Hainan General Hospital/Hainan Affiliated Hospital of Hainan Medical UniversityHaikou 570311Hainan ProvinceChina

BACKGROUND Sepsis usually causes hemodynamic *** index is one of the factors to identify the severity of sepsis and an important parameter to guide the procedure of fluid *** present study investigated whether the assessment of hemodynamic indices can predict the outcomes of septic patients undergoing resuscitation *** To evaluate the prognostic value of hemodynamic indices in patients with sepsis after fluid *** A retrospective study was conducted in 120 patients with sepsis at Hainan General Hospital/Hainan Affiliated Hospital of Hainan Medical University between October 2016 and October *** patients were treated with sodium chloride combined with dextran glucose injection for fluid ***’hemodynamic parameters were monitored,including heart rate(HR),cardiac index(CI),systemic vascular resistance index(SVRI),mean arterial pressure(MAP),central venous pressure(CVP),and central venous oxygen *** prognostic value of hemodynamic indices was determined based on the prognosis *** During fluid resuscitation,86 patients developed septic shock and 34 did ***-nine patients survived and 21 patients died at 28 d after the *** rate,CI,mean arterial pressure,SVRI,and CVP were higher in patients with septic shock and patients who died from septic shock than in non-shock patients and patients who survived,and central venous oxygen saturation was lower in patients with shock and patients who died than in non-shock patients and thesurvivors (P hen prognosis was considered as a dependent variable andhemodynamic parameters was considered as independent variables, the results ofa logistic regression analysis showed that CI, SVRI, and CVP were independentrisk factors for septic shock, and CI was an independent risk factor for 28-dmortality (P hemodynamic indices can be used to evaluate the prognosis of septic patientsafter fluid resusc

关键词： Sepsis Fluid resuscitation Cardiac index Systemic vascular resistance index Mean arterial pressure

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Gametic selection in a doubled haploid population derived from anther culture of indica/japonica hybrid of Oryza Sativa L.

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Chinese Rice Research Newsletter 1998年第4期6卷 2-3页

作者： CheN Ying LU Chaofu he ping SheN Lishuang xu Jichen ZHU Lihuang,Inst of Genetics,Academia Sinica,Beijing 100101 xu Yunbi Dept of Agro,Zhejiang Agri Univ,Hangzhou 310029,China

It is one of the key problems for application ofanther culture in hybrid breeding, geneticanalysis, and molecular mapping whether thedoubled haploid (DH) population derived fromanther culture of rice crosses represents a ran-dom array of the microspore population, *** gametic selection occurs in androgene-sis. A DH population including 132 lines de-

关键词： Gametic selection in a doubled haploid population derived from anther culture of indica/japonica hybrid of Oryza Sativa L

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分数阶阻尼裂纹转子的小波尺度谱分析方法研究

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兵工学报 2014年第8期35卷 1281-1287页

作者：李志农王海峰何旭平肖尧先南昌航空大学无损检测技术教育部重点实验室江西南昌330063

结合在分数阶微积分的基础上建立的裂纹转子系统模型和小波尺度谱,提出基于小波尺度谱的分数阶阻尼的转子裂纹故障诊断方法,并讨论了不同的裂纹深度下分数阶阻尼的裂纹转子系统的小波尺度谱和重分配尺度谱特性。仿真结果表明,分数阶阶... 详细信息

结合在分数阶微积分的基础上建立的裂纹转子系统模型和小波尺度谱,提出基于小波尺度谱的分数阶阻尼的转子裂纹故障诊断方法,并讨论了不同的裂纹深度下分数阶阻尼的裂纹转子系统的小波尺度谱和重分配尺度谱特性。仿真结果表明,分数阶阶次的改变对系统运动特性有很大的影响,在建立动力学模型时可以灵活调节分数阶阶次来改变转子系统的振动特性以达到诊断转子裂纹的最佳效果。提出的方法对裂纹故障敏感,能有效地提取裂纹转子系统中的故障信息。最后用实验进行了验证,实验结果与理论数值分析的结果相吻合,验证了文中建立的分数阶阻尼的裂纹转子系统模型的正确性。

关键词：动力机械工程小波尺度谱分数阶微积分裂纹转子故障诊断

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Comment on “A photometric investigation of ultra-efficient LEDs with high color rendering index and high luminous efficacy employing nanocrystal quantum dot luminophores”

Comment on “A photometric investigation of ultra-efficient ...

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中国光学学会2011年学术大会

作者： Guoxing he, ping Zhong and Jing xu Department of Applied Physics,Dong Hua University,1882 Yan’an Road(W),Shanghai 200051,China

This is a comment on "A photometric investigation of ultraefficient LEDs with high color rendering index and high luminous efficacy employing nanocrystal quantum dot luminophores"（Optics Express 18（1）,340-347,2010）.The results simulated by using a 1 nm step size of both wavelength and FWHM intervals show that all previous conclusions need to *** highest possible CRI value is above 99 at CCT ＞ 2200 K for CRI ＞ 80 and LER ＞300 lm/*** FWHM of each color NC luminophore should be 30 nm to obtain high optical performance in designing NC based *** ultra-efficient and extrahigh color rendering LEDs CRI ≥ 90 and LER ＞ 400 lm/W,with CRI ≥ 95 and LER ＞ 380 lm/W,with CRI ≥ 96 and LER ＞ 370 lm/W,with CRI ≥ 98 and LER ＞ 360 lm/W,as well as with CRI ≥ 99 and LER ＞ 340 lm/W at a CCT of 3000 K are shown to be achieved using nanocrystal *** peak emission wavelength for each NC luminophore has a strong restriction to satisfy the conditions of CRI ＞ 80 and LER ＞ 420 lm/W,CRI ＞ 90 and LER ＞ 400 lm/W,as well as CRI ＞ 95 and LER ＞ 380 lm/*** average and standard deviation are presented.

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我国农业环境司法保护若干问题探析

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科技与法律 2008年第4期 23-26页

作者：徐和平安徽广播电视大学文法部

农业环境的法治建设既是构建和谐农村社会的应有之义,也是社会主义新农村建设的重要内容。针对我国农业环境法治建设中立法体系较为完备、执法机制较为健全而司法制度则相对滞后的现实,有必要加强农业环境司法保护的制度建设,创新符合... 详细信息

农业环境的法治建设既是构建和谐农村社会的应有之义,也是社会主义新农村建设的重要内容。针对我国农业环境法治建设中立法体系较为完备、执法机制较为健全而司法制度则相对滞后的现实,有必要加强农业环境司法保护的制度建设,创新符合农业环境案件审判和执行要求的司法机制,从而整体推进我国农业环境保护的法治建设。

关键词：农业环境司法保护探析

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Multifunctional Nacre-Like Nanocomposite Papers for Electromagnetic Interference Shielding via heterocyclic Aramid/MXene Template-Assisted In-Situ Polypyrrole Assembly

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NANO-MICRO LETTERS 2025年第1期17卷 1-18页

作者： Xiong, Jinhua Zhao, xu Liu, Zonglin Chen, he Yan, Qian Lian, Huanxin Chen, Yunxiang Peng, Qingyu he, Xiaodong Harbin Inst Technol Ctr Composite Mat & Struct Natl Key Lab Sci & Technol Adv Composites Special Harbin 150080 Peoples R China

The large-scale, high-strength, super-tough, and multifunctional nacre-like heterocyclic aramid (HA)/MXene@polypyrrole (PPy) (HMP) nanocomposite papers were fabricated using the in-situ assembly of PPy onto the HA/MXene hydrogel *** "brick-and-mortar" layered structure and abundant hydrogen-bonding interactions among MXene, PPy, and HA respond cooperatively to external stress and effectively increase the mechanical properties of HMP nanocomposite *** templating effect from HA/MXene was utilized to guide the assembly of conducting polymers, leading to high electrical conductivity and outstanding electromagnetic interference shielding performance. Robust, ultra-flexible, and multifunctional MXene-based electromagnetic interference (EMI) shielding nanocomposite films exhibit enormous potential for applications in artificial intelligence, wireless telecommunication, and portable/wearable electronic equipment. In this work, a nacre-inspired multifunctional heterocyclic aramid (HA)/MXene@polypyrrole (PPy) (HMP) nanocomposite paper with large-scale, high strength, super toughness, and excellent tolerance to complex conditions is fabricated through the strategy of HA/MXene hydrogel template-assisted in-situ assembly of PPy. Benefiting from the "brick-and-mortar" layered structure and the strong hydrogen-bonding interactions among MXene, HA, and PPy, the paper exhibits remarkable mechanical performances, including high tensile strength (309.7 MPa), outstanding toughness (57.6 MJ m-3), exceptional foldability, and structural stability against ultrasonication. By using the template effect of HA/MXene to guide the assembly of conductive polymers, the synthesized paper obtains excellent electronic conductivity. More importantly, the highly continuous conductive path enables the nanocomposite paper to achieve a splendid EMI shielding effectiveness (EMI SE) of 54.1 dB at an ultra-thin thickness (25.4 mu m) and a high specific EMI SE of 17,204.7 dB cm2 g-1. In addit

关键词： MXene Remarkable mechanical properties heterocyclic aramid Electromagnetic interference shielding Polypyrrole Multifunctionality

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Fe-Mn合金层错能的嵌入原子法计算

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上海交通大学学报 2003年第2期37卷 171-174页

作者：戎咏华孟庆平何刚徐祖耀上海交通大学材料科学与工程学院上海200030

运用嵌入原子法 (EAM)计算了 Fe- Mn合金层错能 (SFE) .采用 Johnson截断修正模型计算的结果表明 ,Fe- Mn合金的层错能随 Mn含量的增加而线性增大 .该趋势与本文实验结果一致 ,而且 Fe- 2 0 Mn(原子分数 ,% )合金中的层错能计算结果 (2 ... 详细信息

运用嵌入原子法 (EAM)计算了 Fe- Mn合金层错能 (SFE) .采用 Johnson截断修正模型计算的结果表明 ,Fe- Mn合金的层错能随 Mn含量的增加而线性增大 .该趋势与本文实验结果一致 ,而且 Fe- 2 0 Mn(原子分数 ,% )合金中的层错能计算结果 (2 8m J/m2 )与 Kato等的热力学计算结果(2 6m J/m2 )较为吻合 .当 a(Mn) =2 0 %～ 55%时 ,γ相的层错能可表达为 :SFE(m J/m2 ) =2 3.3+0 .2 69×a(Mn) % .

关键词：嵌入原子法层错能 Fe-Mn合金

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Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2

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Neural Regeneration Research 2025年第6期20卷 1801-1815页

作者： Qing he Zhen Wang Yuchen Wang Mengjie Zhu Zhile Liang Kanghong Zhang Yuge xu Gong Chen GHM Institute of CNS Regeneration Jinan UniversityGuangzhouGuangdong ProvinceChina

Direct in vivo conversion of astrocytes into functional new neurons induced by neural transcription factors has been recognized as a potential new therapeutic intervention for neural injury and degenerative disorders. However, a few recent studies have claimed that neural transcription factors cannot convert astrocytes into neurons, attributing the converted neurons to pre-existing neurons mis-expressing transgenes. In this study, we overexpressed three distinct neural transcription factors––NeuroD1, Ascl1, and Dlx2––in reactive astrocytes in mouse cortices subjected to stab injury, resulting in a series of significant changes in astrocyte properties. Initially, the three neural transcription factors were exclusively expressed in the nuclei of astrocytes. Over time, however, these astrocytes gradually adopted neuronal morphology, and the neural transcription factors was gradually observed in the nuclei of neuron-like cells instead of astrocytes. Furthermore,we noted that transcription factor-infected astrocytes showed a progressive decrease in the expression of astrocytic markers AQP4(astrocyte endfeet signal), CX43(gap junction signal), and S100β. Importantly, none of these changes could be attributed to transgene leakage into preexisting neurons. Therefore, our findings suggest that neural transcription factors such as NeuroD1, Ascl1, and Dlx2 can effectively convert reactive astrocytes into neurons in the adult mammalian brain.

关键词： aquaporin-4 Ascl1 astrocyte cortex Dlx2 gap junction glia-to-neuron conversion neural regeneration NeuroD1 reprogramming

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Resting-state brain network remodeling after different nerve reconstruction surgeries:a functional magnetic resonance imaging study in brachial plexus injury rats

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Neural Regeneration Research 2025年第5期20卷 1495-1504页

作者： Yunting Xiang Xiangxin Xing xuyun Hua Yuwen Zhang Xin xue Jiajia Wu Mouxiong Zheng he Wang Jianguang xu School of Rehabilitation Science Shanghai University of Traditional Chinese MedicineShanghaiChina Engineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation Ministry of EducationShanghaiChina Department of Rehabilitation Medicine Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Department of Traumatology and Orthopedics Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Institute of Science and Technology for Brain-Inspired Intelligence Fudan UniversityShanghaiChina Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence(Fudan University) Ministry of EducationShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected ***,differences among reconstruction strategies at the brain network level have not been *** study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve ***–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper ***-state brain functional magnetic resonance imaging was obtained 7 months after *** independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the *** in intra-network resting-state functional connectivity were compared among the *** muscle reinnervation was assessed by behavioral observation(elbow flexion)and *** results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural *** repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor *** thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve *** areas related to cognition and emotion were enhanced after end-to-side nerve *** study revealed important brain networks related to different nerve *** networks may be potential targets for enhancing motor recovery.

关键词： brain functional networks end-to-end nerve transfer end-to-side nerve transfer independent component analysis nerve repair peripheral plexus injury resting-state functional connectivity

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口服营养补充依从性的影响因素

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肿瘤代谢与营养电子杂志 2017年第2期4卷 232-241页

作者：何平许可敏刘江南石汉平纽迪希亚制药(无锡)有限公司研发部江苏无锡214111 中国科学院北京转化医学研究院/航空总医院肿瘤医学中心/普外科北京100012

ONS能增加患者营养素摄入,改善其营养不良状态,然而目前研究发现ONS的依从性较低。本项研究旨在探索影响ONS适口性的相关因素,对营养不良患者ONS的依从性的影响,采用关键词:适口性、口感、口味、香味、风味、接受度、依从性、ONS、肠内... 详细信息

ONS能增加患者营养素摄入,改善其营养不良状态,然而目前研究发现ONS的依从性较低。本项研究旨在探索影响ONS适口性的相关因素,对营养不良患者ONS的依从性的影响,采用关键词:适口性、口感、口味、香味、风味、接受度、依从性、ONS、肠内营养、营养补充剂等,检索MEDLINE、Sci Search、AGRICOLA、BIOSIS Previews、CAB ABSTRACTS、Embase、Foodline、中国生物医学文献数据库、中国知网数据库,按照纳入和排除标准对搜索的文献进行分析和总结。根据文献检索结果,最终将影响因素归纳为三大类,包括ONS产品本身、患者个人情况和患者环境因素;进一步细分为:营养素、口味、能量密度、ONS容量、黏度、个体消化机制、年龄、患者病情、摄入时间、社会疏离感、鼓励措施。研究发现,小剂量、高能量密度的ONS能够促进营养摄入。患者营养状况越来越受到医疗工作者的重视,需要尽早通过营养筛查等方法确定患者营养不良状态,借鉴ONS依从性的影响因素,根据不同患者对营养的需求,设计不同营养处方、以个性化的方式提高营养摄入,增强依从性是今后增强人群营养摄入的关键方向。

关键词：营养不良口服营养补充影响因素依从性

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