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莪术油葡萄糖注射液与7种抗菌药物的配伍稳定性

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中国临床药学杂志 2005年第4期14卷 252-254页

作者：贺小青浙江省台州市中医院药剂科台州318000

目的观察莪术油葡萄糖注射液与7种常用抗菌药物配伍后的稳定性。方法用紫外分光光度法测定莪术油葡萄糖注射液中主成分莪术醇6 h内含量的变化,同时观察配伍溶液的外观并测定其pH值、微粒数以及细菌内毒素。结果莪术油葡萄糖注射液与7种... 详细信息

目的观察莪术油葡萄糖注射液与7种常用抗菌药物配伍后的稳定性。方法用紫外分光光度法测定莪术油葡萄糖注射液中主成分莪术醇6 h内含量的变化,同时观察配伍溶液的外观并测定其pH值、微粒数以及细菌内毒素。结果莪术油葡萄糖注射液与7种抗菌药物配伍后,样品液均无气体或沉淀产生;pH值、微粒数、色泽在6 h内均无明显改变,室温下放置的配伍液6 h时细菌内毒素检查也符合规定。与左氧氟沙星、哌拉西林钠、头孢唑啉钠、克林霉素、阿昔洛韦、氨苄西林钠配伍后6h内相对百分含量均>90%;与头孢哌酮钠配伍含量下降最大,样品液由浅黄色变成深黄色;结论莪术油葡萄糖注射液与左氧氟沙星、哌拉西林钠、克林霉素、阿昔洛韦、头孢唑啉钠、氨苄西林钠可配伍使用,不宜与头孢哌酮钠配伍。

关键词：莪术油葡萄糖注射液莪术醇配伍稳定性抗菌药物

Exploring the relationship between red blood cell levels and emotional regulation through the miR191-Riok3-Mxi1 pathway

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Journal of Traditional Chinese Medical Sciences 2024年第1期11卷 101-110页

作者： Da Zhang xiaoqing Zhang Li Yang Yan Zhao Xingang Hu School of Life Sciences Beijing University of Chinese MedicineBeijing 102488China School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing 102488China Dongfang Hospital Beijing University of Chinese MedicineBeijing 100078China

Objective:To assess emotional fluctuations,physical and mental health status,and indicators closely related to red blood cells,such as RIO kinase 3(Riok3),MAX interactor 1(Mxi1),and microRNA 191(miR191),in participants with different levels of red blood ***:Participants who underwent physical examinations at Dongfang Hospital between April and October 2019 were divided into healthy,blood deficiency,and anemia groups(30 individuals in the healthy and blood deficiency group respectively,and 13 in the anemia group).The physical and mental conditions of the participants were evaluated through questionnaires,and emotional fluctuations were assessed through an emotion-inducing experiment,in which participants watched video segments designed to induce specific *** expression levels of miR191,Riok3,and Mxi1 from venous blood samples were also ***:The main psychological factors identified in the anemia and blood deficiency groups were obsessive-compulsive symptoms,depression,anxiety,and other negative *** gene expression levels indicated that miR191 was upregulated and Riok3 and Mxi1 were downregulated in both the blood deficiency and anemia *** the emotional score of disgust on video stage,the main effect was significant(F=335.58,Phe three videos caused participants to have a dominant emotion,and there is a difference on group(F=5.35,P=.01),with higher disgust scores in the anemia and blood deficiency *** symptoms of blood deficiency and anemia,such as weakness in limbs were significantly negatively correlated with Riok3 and Mxi1 expression(r=-0.38 and-0.31 respectively),but was significantly positively correlated with miR191 expression(r=0.29).Conclusion:We determined that a close relationship exists between red blood cell levels and emotional *** findings suggest that individuals with anemia and blood deficiency are more likely to experience psychological pro

关键词： Anemia Blood deficiency Emotional regulation miR191-Riok3-Mxi1 pathway Emotion-inducing experiments

延伸信息化管理在食管胃底静脉破裂出血患者内镜套扎术联合组织胶栓塞术后的应用

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智慧健康 2023年第5期9卷 250-254页

作者：何小青信宜市人民医院广东信宜525300

目的探究延伸信息化管理在食管胃底静脉破裂出血患者内镜套扎术联合组织胶栓塞术后的应用价值。方法收集2020年6月-2022年1月在信宜市人民医院经内镜套扎术联合组织胶栓塞术治疗的肝硬化食管胃底静脉曲张破裂出血患者64例,随机划分为... 详细信息

目的探究延伸信息化管理在食管胃底静脉破裂出血患者内镜套扎术联合组织胶栓塞术后的应用价值。方法收集2020年6月-2022年1月在信宜市人民医院经内镜套扎术联合组织胶栓塞术治疗的肝硬化食管胃底静脉曲张破裂出血患者64例,随机划分为两组,研究组与参照组,各32例。参照组实施综合围术期管理,研究组则基于参照组方案实施延伸信息化管理。比较两组术后不同时间点疼痛VAS评分、管理前后心理状态评分与自我管理能力评分、术后并发症发生率。结果研究组术后24h、48h、72h的VAS评分均低于参照组(P<0.05);管理后研究组HAMA评分及HAMD评分均低于参照组,自我管理能力评分高于参照组(P<0.05);研究组术后并发症发生率低于参照组(P<0.05)。结论在食管胃底静脉破裂出血患者经内镜套扎术联合组织胶栓塞术治疗期间实施延伸信息化管理,可缓解患者疼痛,改善情绪,促患者自我管理能力提升,规避术后并发症,值得推广。

关键词：延伸信息化管理食管胃底静脉破裂出血内镜套扎术联合组织胶栓塞术

Analysis of faulting destruction and water supply pipeline damage from the first mainshock of the February 6,2023 Türkiye earthquake doublet

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Earthquake Science 2024年第1期37卷 78-90页

作者： xiaoqing Fan Libao Zhang Juke Wang Yefei Ren Aiwen Liu Institute of Geophysics China Earthquake AdministrationBeijing 100081China Institute of Engineering Mechanics China Earthquake AdministrationHarbin 150080China

In 2023,two consecutive earthquakes exceeding a magnitude of 7 occurred in Türkiye,causing severe casualties and economic *** damage to critical urban infrastructure and building structures,including highways,railroads,and water supply pipelines,was particularly severe in areas where these structures intersected the seismogenic *** infrastructure projects that traverse active faults are susceptible to the influence of fault movement,pulse velocity,and ground *** this study,we used a unique approach to analyze the acceleration records obtained from the seismic station array(9 strong ground motion stations)located along the East Anatolian Fault(the seismogenic fault of the MW7.8 mainshock of the 2023 Türkiye earthquake doublet).The acceleration records were filtered and integrated to obtain the velocity and displacement time *** used the results of an on-site investigation,jointly conducted by China Earthquake Administration and Türkiye’s AFAD,to analyze the distribution of PGA,PGV,and PGD recorded by the strong motion array of the East Anatolian *** found that the maximum horizontal PGA in this earthquake was 3.0 g,and the maximum co-seismic surface displacement caused by the East Anatolian Fault rupture was 6.50 *** the fault rupture propagated southwest,the velocity pulse caused by the directional effect of the rupture increased gradually,with the maximum PGA reaching 162.3 cm/*** also discussed the seismic safety of critical infrastructure projects traversing active faults,using two case studies of water supply pipelines in Türkiye that were damaged by *** used a three-dimensional finite element model of the PE(polyethylene)water pipeline at the Islahiye State Hospital and fault displacement observations obtained through on-site investigation to analyze pipeline failure *** further investigated the effect of the fault-crossing angle on seismic safety of a pipeline,based on our analysis and the failure p

关键词： Türkiye earthquake fault displacement near-fault ground motion velocity pulse water supply pipeline

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培养英语阅读能力初探

南平师专学报 2002年第3期21卷 107-109页

作者：何小青福建农林大学人文社科学院南平校区福建南平353001

本文从分析学生阅读中常出现的错误出发 ,提出以意群为单位进行阅读 ,以及根据所学知识和上下文猜测单词 ,综合运用浏览、查阅、研读等来提高阅读水平的方法。

关键词：意群预览略读转化派生合成阅读

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大学生思想政治教育创新发展路径探究

泉州师范学院学报 2016年第3期34卷 100-104页

作者：何小青漳州职业技术学院福建漳州363000

当前高校大学生思想政治教育存在对理论武装工作重视不够,无法适应"互联网+"发展新常态,学校、家庭、社会尚未完全形成三位一体统筹推进等问题,导致部分学生思想政治立场不够坚定、改革创新意识不强、责任担当精神不足。因此,要旗帜鲜... 详细信息

当前高校大学生思想政治教育存在对理论武装工作重视不够,无法适应"互联网+"发展新常态,学校、家庭、社会尚未完全形成三位一体统筹推进等问题,导致部分学生思想政治立场不够坚定、改革创新意识不强、责任担当精神不足。因此,要旗帜鲜明地用马克思主义中国化及其最新理论成果来引领大学生思想政治教育发展方向,与时俱进地创新"互联网+"时代的最优教育模式改进大学生思想政治教育,举高校、家庭、社会的最大教育合力推进大学生思想政治教育创新发展。

关键词：高等教育改革大学生思想政治教育

糖尿病合并脑梗死偏瘫患者应用早期康复健康管理与护理的临床效果

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糖尿病新世界 2022年第8期25卷 120-123页

作者：何小青福建省立医院福建福州350100

目的分析将早期康复健康管理及护理运用在糖尿病合并脑梗死偏瘫患者临床干预中的效果。方法选择该院2019年8月—2021年9月收治的100例糖尿病合并脑梗死偏瘫患者,给予患者护理干预,将其随机分为两组,对照组采用常规护理方法,观察组在... 详细信息

目的分析将早期康复健康管理及护理运用在糖尿病合并脑梗死偏瘫患者临床干预中的效果。方法选择该院2019年8月—2021年9月收治的100例糖尿病合并脑梗死偏瘫患者,给予患者护理干预,将其随机分为两组,对照组采用常规护理方法,观察组在对照组基础上采用早期康复管理与护理干预,对比两组的护理效果。结果干预后,观察组患者的空腹血糖为(6.72±2.13)mmol/L,餐后2 h血糖为(10.04±2.10)mmol/L,运动功能评分为(50.45±3.22)分、上肢体功能评分为(65.45±1.24)分、下肢体功能评分为(28.93±1.23)分、日常生活能力评分为(3.76±2.22)分,组间对比差异有统计学意义(t=2.404、2.420、15.104、48.623、36.322、6.621,P<0.05)。观察组患者的护理满意度为96.00%,优于对照组,组间对比差异有统计学意义(P<0.05)。结论在糖尿病合并脑梗死偏瘫患者临床干预中运用早期康复健康管理及护理,患者血糖、肢体功能、日常生活能力等指标均明显改善,临床应用效果好,值得广泛推荐应用。

关键词：糖尿病脑梗死偏瘫早期康复健康管理护理效果

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MICP技术在工程应用中的研究进展

山西建筑 2021年第22期47卷 155-156,161页

作者：贺小青西安交通工程学院土木工程学院陕西西安710300

微生物诱导碳酸钙沉积技术(Microbial Induced Carbonate Precipitation,简称MICP技术)在土木工程,特别是岩土工程应用中具有广阔的发展潜力,其施工过程中具有良好的流动性,具有较好的可注入性。反应生成的具有胶结性的碳酸钙,结构致密... 详细信息

微生物诱导碳酸钙沉积技术(Microbial Induced Carbonate Precipitation,简称MICP技术)在土木工程,特别是岩土工程应用中具有广阔的发展潜力,其施工过程中具有良好的流动性,具有较好的可注入性。反应生成的具有胶结性的碳酸钙,结构致密,强度较高,可用来固化松散的土体、修复混凝土裂缝、抗渗建筑材料、治理重金属或放射性金属等。该技术能够克服传统施工技术带来的环境问题,是一种绿色环保新型技术。MICP技术的应用范围、存在的问题及对未来研究方向值得探讨。

关键词：微生物矿化砂土固化防水防渗污染土治理

Mixed-decomposed convolutional network:A lightweight yet efficient convolutional neural network for ocular disease recognition

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CAAI Transactions on Intelligence Technology 2024年第2期9卷 319-332页

作者： xiaoqing Zhang Xiao Wu Zunjie Xiao Lingxi Hu Zhongxi Qiu Qingyang Sun Risa Higashita Jiang Liu Research Institute of Trustworthy Autonomous Systems and Department of Computer Science and Engineering Southern University of Science and TechnologyShenzhenChina Tomey Corporation NagoyaJapan Guangdong Provincial Key Laboratory of Brain‐inspired Intelligent Computation Department of Computer Science and EngineeringSouthern University of Science and TechnologyShenzhenChina Singapore Eye Research Institute SingaporeSingapore

Eye health has become a global health concern and attracted broad *** the years,researchers have proposed many state-of-the-art convolutional neural networks(CNNs)to assist ophthalmologists in diagnosing ocular diseases efficiently and ***,most existing methods were dedicated to constructing sophisticated CNNs,inevitably ignoring the trade-off between performance and model *** alleviate this paradox,this paper proposes a lightweight yet efficient network architecture,mixeddecomposed convolutional network(MDNet),to recognise ocular *** MDNet,we introduce a novel mixed-decomposed depthwise convolution method,which takes advantage of depthwise convolution and depthwise dilated convolution operations to capture low-resolution and high-resolution patterns by using fewer computations and fewer *** conduct extensive experiments on the clinical anterior segment optical coherence tomography(AS-OCT),LAG,University of California San Diego,and CIFAR-100 *** results show our MDNet achieves a better trade-off between the performance and model complexity than efficient CNNs including MobileNets and ***,our MDNet outperforms MobileNets by 2.5%of accuracy by using 22%fewer parameters and 30%fewer computations on the AS-OCT dataset.

关键词： artificial intelligence deep learning deep neural networks image analysis image classification medical applications medical image processing